Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T71921 |
cis-Epoxysuccinic acid
|
Others | Others |
cis-Epoxysuccinic acid 是succinate receptor(SUCNR1/GPR91)的激动剂,能够降低cAMP水平,其EC50值为2.7 µM。它适用于心血管系统的研究。 | |||
T70308 |
PLX7683
|
Others | Others |
PLX7683 is a paradox breaker. Paradox breakers overcame several known mechanisms of resistance to first-generation RAF inhibitors. Dissociating MAPK pathway inhibition from paradoxical activation might yield both improved safety and more durable efficacy than first-generation RAF inhibitors |