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Search Results for " pkc 9 "

Targets Recommended: Others

7

抑制剂 & 化合物

6

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T71993	PKC-9	Others	Others
	PKC-9 is a PKC-zeta inhibitor 9.
T16104	ML-9	Myosin; Akt	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	ML-9 是 Akt 激酶的一种选择性强效抑制剂，可抑制肌球蛋白轻链激酶 (MLCK) 和基质相互作用分子1(STIM1) 活性。它通过刺激自噬小体的形成并抑制其降解来诱导自噬。它抑制 MLCK，PKA 和 PKC 活性，Ki 值分别为 4、32 和 54 μM。
T6285	GSK-690693 GSK690693	Serine Protease; Akt; PKC; AMPK; Autophagy	Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	GSK-690693 是一种泛 Akt 抑制剂，对 Akt1、Akt2和 Akt3的 IC50分别为 2 nM、13 nM 和9 nM。它也是一种 AMPK 的抑制剂，影响 ULK1 的活性，并能显著抑制 STING 依赖的 IRF3 的激活。
T6458	CYC-116 噻氯匹定	VEGFR; FLT; CDK; S6 Kinase; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	CYC116是一种有效的极光激酶 A 和 B 的抑制剂，Ki 值分别为8和9 nM。
T16103	ML-9 Free Base	Others	Others
	ML-9 (free base) suppresses MLCK, PKA, and PKC activity (Ki: 4, 32, and 54 μM, respectively). ML-9 (free base) is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) acti
T36228	Bisindolylmaleimide XI hydrochloride	Others	Others
	Bisindolylmaleimide XI hydrochloride 是一种具有口服活性的 PKC 抑制剂，对 PKCα、PKCβI、PKCβII、PKCγ 具有抑制作用（IC50s 分别为 9 nM、28 nM、31 nM、37 nM 和 108 nM）。
T35423	7-oxo Staurosporine	Others	Others
	7-oxo Staurosporine is an antibiotic originally isolated from S. platensis with diverse biological activites. It inhibits PKC, PKA, phosphorylase kinase, EGFR, and c-Src in vitro (IC50s = 9, 26, 5, 200, and 800 nM, respectively). 7-oxo Staurosporine induces cell cycle arrest in the G2/M phase in human leukemia K562 cells with a minimal effective dose (MED) of 30 ng/ml. It is cytotoxic to P388 mouse leukemia cells that are resistant and susceptible to doxorubicin . 7-oxo Staurosporine inhibits gr...

化合物

Cat.No: T71993

Target: Others

Cat.No: T16104

Target: Myosin, Akt

Cat.No: T6285

Synonym: GSK690693

Target: Serine Protease, Akt, PKC, AMPK, Autophagy

Cat.No: T6458

Synonym: 噻氯匹定

Target: VEGFR, FLT, CDK, S6 Kinase, Aurora Kinase

Cat.No: T16103

Target: Others

Bisindolylmaleimide XI hydrochloride

Cat.No: T36228

Target: Others

7-oxo Staurosporine

Cat.No: T35423

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His) VEGFA,VEGF-A,Vascular permeability factor,VPF,血管内皮生长因子,Vascu...	Human	HEK293 Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessel...
TMPY-03698	VEGF121b Protein, Human, Recombinant MVCD1,VEGF,VPF,vascular endothelial growth factor A	Human	HEK293 Cells
	VEGF121b Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 34.10 kDa and the accession number is P15692-9.
TMPH-00005	YAP1 Protein, Human, Recombinant (Isoform 9, His) Protein yorkie homolog,YAP1,Yes-associated protein YAP65 hom...	Human	P. pastoris (Yeast)
	YAP1 Protein, Human, Recombinant (Isoform 9, His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 56.4 kDa; 80 kDa, reducing conditions and the accession number is P46937-9.
TMPK-00825	VEGF121 Protein, Human, Recombinant (His & Avi) VPF,VEGF,VEGFA,VEGFMGC70609,血管内皮生长因子,MGC70609	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9.
TMPK-00826	VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated VAS,VEGFMGC70609,RP1-261G23.1,血管内皮生长因子,VEGFA,VPF,MV...	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9.
TMPY-05268	Neurofascin Protein, Human, Recombinant (hFc), Biotinylated NRCAML,neurofascin,NF	Human	HEK293 Cells
	Neurofascin Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 130 kDa and the accession number is O94856-9.

重组蛋白

VEGF121 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00865

Species: Human

Expression System: HEK293 Cells

VEGF121b Protein, Human, Recombinant

Cat.No: TMPY-03698

Species: Human

Expression System: HEK293 Cells

YAP1 Protein, Human, Recombinant (Isoform 9, His)

Cat.No: TMPH-00005

Species: Human

Expression System: P. pastoris (Yeast)

VEGF121 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00825

Species: Human

Expression System: HEK293 Cells

VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00826

Species: Human

Expression System: HEK293 Cells

Neurofascin Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05268

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T71401	Oxaliplatin-d10
	Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2....

同位素标记化合物

Oxaliplatin-d10

Cat.No: T71401

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