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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T24646 |
PK-3
CID-20959075,CID 20959075,CID20959075 |
Others | Others |
PK-3 is a cancer cell growth inhibitor. It also has microtubule-binding activity. | |||
T63544 |
RIPK3-IN-1
|
Apoptosis; c-Met/HGFR; RIP kinase | Apoptosis; NF-κB; Tyrosine Kinase/Adaptors |
RIPK3-IN-1 是一种具有选择性和高效性的 RIPK3 抑制剂(IC50为 9.1 nM),抑制 c-Met 激酶、RIPK1 和 RIPK2 的活性。RIPK3-IN-1 具有潜在的看肿瘤活性,可用于研究细胞凋亡。 | |||
T62569 |
RIPK3-IN-2
|
Others | Others |
RIPK3-IN-2 是一种 RIP3 抑制剂,能够用于由激活的坏死途径引起或与之相关的疾病研究。 | |||
T81267 |
RIPK3-IN-4
|
RIP kinase | Apoptosis; NF-κB |
RIPK3-IN-4(Compound 42)是一种抑制RIPK3活性的化合物。它能有效减轻HK-2细胞的损伤和凋亡(necroptosis),同时降低急性肾损伤中(Cisplatin)以及缺血/再灌注(I/R)引起的肾脏损伤、炎症及坏死性凋亡现象。 | |||
T78784 |
RIPK3-IN-3
|
Others | Others |
RIPK3-IN-3(化合物20)是一种针对受体相互作用蛋白激酶RIPK3的选择性抑制剂,其IC50为10 nM。它通过抑制p-MLKL的寡聚化作用来阻止RIPK3介导的MLKL磷酸化以及随后的坏死性凋亡。此外,RIPK3-IN-3还能降低CXCL5的分泌,并抑制AsPC-1细胞的迁移和侵袭。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04766 |
PKM2 Protein, Mouse, Recombinant (His)
AL024424,AA414905,Pk3,Pk-3 |
Mouse | Baculovirus Insect Cells |
PKM2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60 kDa and the accession number is P52480-2. | |||
TMPY-04465 |
PKM2 Protein, Human, Recombinant (His)
pyruvate kinase, muscle,OIP3,CTHBP,PK3... |
Human | E. coli |
PKM2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 59 kDa and the accession number is P14618-1. | |||
TMPY-04385 |
ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST)
death-associated protein kinase 3,DLK,ZIP,ZIPK<... |
Human | Baculovirus Insect Cells |
Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP kinase subfamily. DAPK3 / ZIPK contains oneprotein kinase domain. It is a serine/threonine kinase which acts as a positive regulator of apoptosis. It phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. DAPK3 / ZIPK is a homodimer or forms heterodimers with AT... | |||
TMPH-01692 |
MAPK3 Protein, Human, Recombinant (His)
MAP kinase isoform p44,p44-ERK1,MAPK3,Extr... |
Human | E. coli |
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, c... | |||
TMPY-04378 |
MAPKAPK3 Protein, Human, Recombinant (GST)
mitogen-activated protein kinase-activated protein kinase |
Human | Baculovirus Insect Cells |
The MAPKAP kinases are a group of MAP kinase substrates that are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identified and serve as substrates for the ERK and p38 MAP kinases. Mitogen-activated protein (MAP) kinase-activated protein kinase 3, also known as MAPKAPK-3 and 3pK, is a member of the Ser/Thr protein kinase family. It is widely expressed in hu... | |||
TMPH-00839 |
RIPK3 Protein, Human, Recombinant (His & SUMO)
Receptor-interacting protein 3,RIPK3 |
Human | E. coli |
RIPK3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 72.9 kDa and the accession number is Q9Y572. | |||
TMPH-02877 |
RIPK3 Protein, Mouse, Recombinant (His)
Receptor-interacting protein 3,Ripk3 |
Mouse | P. pastoris (Yeast) |
RIPK3 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 54.8 kDa and the accession number is Q9QZL0. | |||
TMPH-02375 |
OmpK36 Protein, Klebsiella pneumoniae, Recombinant
ompK36 |
Klebsiella pneumoniae | E. coli |
OmpK36 Protein, Klebsiella pneumoniae, Recombinant is expressed in E. coli. | |||
TMPH-02374 |
OmpK36 Protein, Klebsiella pneumoniae, Recombinant (His)
ompK36 |
Klebsiella pneumoniae | E. coli |
OmpK36 Protein, Klebsiella pneumoniae, Recombinant (His) is expressed in E. coli. | |||
TMPH-02967 |
UPK3A Protein, Mouse, Recombinant (His & Myc)
Uroplakin-3a,Upk3a,Uroplakin III |
Mouse | E. coli |
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence. UPK3A Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The pre... | |||
TMPY-04565 |
SRPK3 Protein, Human, Recombinant (His & GST)
MSSK1,MGC102944,STK23,MSSK-1,SRSF protein kinase |
Human | Baculovirus Insect Cells |
Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine / threonine-protein kinase 23, MSSK-1, SRPK3 and MSSK1, is a member of the protein kinase superfamily and CMGC Ser / Thr protein kinase family. SRPK3 is a protein kinase belonging to serine/arginine protein kinases (SRPK) family, which phosphorylates serine / arginine repeat-containing proteins, and is controlled by a muscle-... | |||
TMPH-02009 |
RIPK3 Protein, Human, Recombinant (His)
RIPK3,RIP-like protein kinase 3,R... |
Human | P. pastoris (Yeast) |
RIPK3 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 58.9 kDa and the accession number is Q9Y572. |