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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T36934 PK7242 (maleate)

PK7242 (maleate)

Others Others
The protein p53, often called the 'guardian of the genome,' is a transcription factor that is activated in response to cellular stress (low oxygen levels, heat shock, DNA damage, etc.) and acts to prevent further proliferation of the stressed cell by promoting cell cycle arrest or apoptosis. Its role as a tumor suppressor is evident by the observation that approximately 50% of human tumors have mutated or non-functional p53. PK7242 is an inducer of reactivation of mutant p53 in cancer cells. In ...

化合物

PK7242 (maleate)
Cat.No: T36934
Synonym: PK7242 (maleate)
Target: Others
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