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Search Results for " pip "

Targets Recommended: Others

377

抑制剂 & 化合物

53

天然产物

4

重组蛋白

7

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T40711	H-D-Phe-Pip-Arg-pNA dihydrochloride S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride	Others	Others
	H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thrombin detection, H-D-Phe-Pip-Arg-pNA dihydrochloride is employed for the quantification of antithrombin-heparin cofactor (AT-III). The AT-III assay utilizing this substrate is characterized by its sensitivity, accuracy, and ease of implementation.
T9126	PIP-199	Others	Others
	PIP-199 是一种 RecQ 介导的基因组不稳定蛋白 RMI 核心复合物/MM2 相互作用 (RMI core complex/MM2 interaction) 的选择性抑制剂，其 IC50值为 36 μM。PIP-199 可用于研究 DNA 交联修复的潜在机制，并可用作增敏化疗耐药肿瘤。
T39066	H-D-Phe-Pip-Arg-pNA hydrochloride S-2238 hydrochloride,H-D-Phe-Pip-Arg-pNA hydrochloride
	H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, mimics the N-terminal segment of the A alpha chain of fibrinogen, the native substrate of thrombin. It displays specificity towards thrombin and is employed for quantifying antithrombin-heparin cofactor (AT-III). The utilization of H-D-Phe-Pip-Arg-pNA hydrochloride in the AT-III assay enables a sensitive, accurate, and straightforward measurement process.
T38542	H-D-Phe-Pip-Arg-pNA acetate H-D-Phe-Pip-Arg-pNA acetate,S-2238 acetate
	H-D-Phe-Pip-Arg-pNA (S-2238) acetate is a chromogenic substrate designed based on the N-terminal fragment of the A alpha chain of fibrinogen, which is the physiological target of thrombin. As a specific indicator of thrombin activity, H-D-Phe-Pip-Arg-pNA acetate is utilized to quantify. This assay, utilizing H-D-Phe-Pip-Arg-pNA acetate, ensures high sensitivity, accuracy, and ease of execution.
T39494	(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH,(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH	Others	Others
	(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, also known as VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, is a conjugate compound comprising a ligand-linker that targets E3 ligase and, on one end, features a VHL ligand. It is employed in PROTAC technology applications.
T18545	Pip-alkyne-Ph-COOCH3	Others	Others
	Pip-alkyne-Ph-COOCH3 is an alkyl-chain based PROTAC linker utilized for the synthesis of PROTAC ARD-266[1].
T84768	Lipid 10 EA-PIP	Others	Others
	Lipid 10，一种具有可电离性的氨基脂质，适用于脂质纳米颗粒的合成。
T17689	Boc-Pip-alkyne-Ph-COOH	Others	Others
	Boc-Pip-alkyne-Ph-COOH, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in synthesizing PROTACs including ARD-266. This compound demonstrates significant efficacy in promoting the degradation of androgen receptor (AR) protein across AR-positive prostate cancer cell lines such as LNCaP, VCaP, and 22Rv1, showcasing DC50 values ranging from 0.2-1 nM[1].
T38795	Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride
	Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate.
T34462	H-D-Phe-Pip-Arg-pNA S2238,S 2238,S-2238
	S 2238 is a chromogenic substrate for thrombin that is used in amidolytic assay.
TMAZ-0234A	Anti-PIP Monoclonal Antibody-APC
	Anti-PIP Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting PIP. Anti-PIP Monoclonal Antibody-APC can be used ELISA, FACS.
TMAZ-0234A5	Anti-PIP Monoclonal Antibody-AF555
	Anti-PIP Monoclonal Antibody-AF555 is a biotin-conjugated humanized rabbit antibody targeting PIP. Anti-PIP Monoclonal Antibody-AF555 can be used ELISA, FACS.
TMAZ-0234P	Anti-PIP Monoclonal Antibody-PE
	Anti-PIP Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting PIP. Anti-PIP Monoclonal Antibody-PE can be used ELISA, FACS.
TMAZ-0234B	Anti-PIP Monoclonal Antibody-Biotin
	Anti-PIP Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting PIP. Anti-PIP Monoclonal Antibody-Biotin can be used ELISA, FACS.
TMAZ-0234A6	Anti-PIP Monoclonal Antibody-AF647
	Anti-PIP Monoclonal Antibody-AF647 is a biotin-conjugated humanized rabbit antibody targeting PIP. Anti-PIP Monoclonal Antibody-AF647 can be used ELISA, FACS.
T39452	PIP4K-IN-a131 PIP4K-IN-a131	Others	Others
	PIP4K-IN-a131 is PIP4K lipid kinases inhibitor, with IC 50 s of 1.9 μM and 0.6 μM for purified PIP4K2A and PIP4Ks, respectively. PIP4K-IN-a131 exhibits cancer-selective lethality via dual blockade of the lipid kinase PIP4Ks and mitotic pathways.
TMAZ-0234A4	Anti-PIP Monoclonal Antibody-AF488
	Anti-PIP Monoclonal Antibody-AF488 is a biotin-conjugated humanized rabbit antibody targeting PIP. Anti-PIP Monoclonal Antibody-AF488 can be used ELISA, FACS.
TP2409	SP-346 nonapeptide H-Val-Ser-Gln-Asn-Tyr-Pip-Ile-Val-Gln-NH2
	SP-346 nonapeptide is a pipecolic acid substituted nonapeptide.
TQ0292	Grapiprant AAT-007,RQ-00000007,CJ-023423	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Grapiprant (AAT-007) 是一种选择性EP4 受体拮抗剂，生理配体为前列腺素 E2(PGE2)，有用于骨关节炎疼痛和炎症的研究潜力。它取代 [3H]-PGE2(1 nM) 与狗的重组EP4 受体结合，IC50为 35 nM，Ki 为 24 nM。
T12482	Pipendoxifene hydrochloride	Estrogen Receptor/ERR	Endocrinology/Hormones
	Pipendoxifene hydrochloride 是雌激素受体的选择性调节剂。
T50034	1-{1H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine 2HCl	Others	Others
	1-{1H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine dihydrochloride （1-PPZ-DHC）是一种用作分子结构单元的化合物。它是天然产物哌嗪的类似物，具有广泛的生物活性，包括抗炎、抗肿瘤和抗菌活性，同时还被研究用于治疗神经系统疾病，如阿尔茨海默氏症和帕金森氏症。
T7405	Piperidolate 二苯哌酯,哌立度酯	AChR	Neuroscience
	Piperidolate 是一种抗毒蕈碱药，可抑制乙酰胆碱引起的异常活性，能抑制大鼠和狗的肠痉挛。
T0396	Pipemidic acid 吡哌酸,Acido pipemidico	Antibacterial; Antibiotic	Microbiology/Virology
	Pipemidic acid (Acido pipemidico) 是一种新型抗菌剂，对革兰氏阴性菌和某些革兰氏阳性细菌具有活性，可研究肠道、泌尿和胆道感染。
T66256	Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate	Factor Xa	Metabolism
	Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 对凝血因子Xa具有抑制作用，可用于研究血栓性静脉炎、动脉粥样硬化、脑栓塞、中风、肺栓塞。
T3965	Fevipiprant QAW039,NVP-QAW039,非维匹仑	GPR; Prostaglandin Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
	Fevipiprant (NVP-QAW039) 是一种选择性、强效、可逆的竞争性 CRTh2 拮抗剂，KD 值为1.1 nM，IC50为0.44 nM，能够引发人体嗜酸性粒细胞的形状变化。
T14319	Aripiprazole Lauroxil	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Aripiprazole lauroxil 是一种长效注射剂 (LAI) 的抗精神病药物，是阿立哌唑的 N-酰氧基甲基前药形式。它能够被体内酯酶裂解为 N-羟甲基阿立哌唑(月桂酸)，再裂解为阿立哌唑，无毒性。
T4570	Pipobroman Vercyte,A-8103,Amedel,哌泊溴烷	Others; DNA Alkylator/Crosslinker	DNA Damage/DNA Repair; Others
	Pipobroman (Vercyte) 是一种烷基化剂，是哌嗪的溴化衍生物。它通过抑制 DNA 和 RNA 聚合酶或减少嘧啶核苷酸掺入 DNA 发挥其作用。它在真性红细胞增多症和原发性血小板增多症中具有良好的临床活性，可用于癌症研究。
T8501	3-Phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-tricyclo[3.3.1.13,7]decane-1-carboxamide	Influenza Virus	Microbiology/Virology
	3-Phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-tricyclo[3.3.1.13,7]decane-1-carboxamide 具有抗埃博拉病毒的抗病毒活性靶向表面暴露的糖蛋白并抑制病毒进入宿主细胞。 Vero 细胞的体外研究表明，该化合物抑制病毒复制，EC50 为 0.38 μM。
T10389L	Aspartyl-alanyl-diketopiperazine acetate DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base)	Others	Others
	Aspartyl-alanyl-diketopiperazine acetate (DA-DKP) 可以通过与 T 淋巴细胞无反应有关的分子途径调节炎症免疫反应。
Fr13199	4-(4-chlorophenyl)piperidin-4-ol	Others	Others
	Compound Fr13199 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 Fr13199，CAS号为 39512-49-7。
Fr13734	Piperonylonitrile 1,3-Benzodioxole-5-carbonitrile	Others	Others
	Compound Fr13734 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 Fr13734，CAS号为 4421-09-4。
T40111L	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 是一种基于间苯二酚二Ph醚支架的程序性细胞死亡-1（PD-1）/程序性细胞死亡配体1（PD-L1）抑制剂, 抑制 PD-1/PD-L1 相互作用，IC50 值为 39.2 nM.BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 包含靶蛋白 PD-1/PD-L1 配体和 PROTAC linker。BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 可用于合成 PROTAC PD-1/PD-L1 degrader-1。BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 具有抗癌活性。BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 可作为稀释剂，用于用于直接压缩制备片剂。
T50061	[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methanamine	Others	Others
	[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methanamine 是一种哌嗪衍生物，它是血清素和多巴胺受体的部分激动剂，使其成为治疗抑郁症和精神分裂症等精神疾病的候选药物。
T60231	N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine	Others	Others
	N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine 是一种生物活性化合物，属于哌嗪类。它是一种重要的合成中间体，用于制备多种药物、农用化学品和其他化学品。它被认为是参与药物代谢的某些酶的抑制剂，例如细胞色素P450酶，也已被证明具有抗炎和抗肿瘤作用。
T77598	Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine (4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone	Others	Others
	Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine ((4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone) 是一种生物合成的原材料，可用于合成多种化合物。
T9361	5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	Others	Others
	5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione (5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) 是一种合成化合物。它已被用作催化剂以及酶动力学研究中的工具；还被用于酶抑制的研究，以及药物受体相互作用的研究。
T2664	Timapiprant OC000459	GPR; Prostaglandin Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
	Timapiprant (OC000459) 是一种有效的选择性 D 前列腺素受体 2(DP2) 拮抗剂，IC50为 13 nM。它抑制肥大细胞激活 Th2 淋巴细胞和嗜酸性粒细胞，有效地置换来自人重组 DP2、大鼠重组 DP2 和人天然 DP2 的 [3H] PGD2。
T77687	3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one	Others	Others
	3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one 在人结肠癌细胞系中显示出抗肿瘤活性，可能用于防治血栓。
T9385	2-(2,6-dioxopiperidin-3-yl)-4-((7-hydroxyheptyl)oxy)isoindoline-1,3-dione	Others	Others
	2-(2,6-dioxopiperidin-3-yl)-4-((7-hydroxyheptyl)oxy)isoindoline-1,3-dione 是 protac。
T9435	1-(4-Carbethoxyphenyl)-piperazin	Others	Others
	1-(4-Carbethoxyphenyl)-piperazin 可作为酶和化学合成的试剂，作为酶研究的模型底物，以及作为受体结合测定的配体。
T0727	Piperonyl butoxide Pyrenone 606,ENT-14250,Ethanol butoxide,Butacide,增效醚	Others; Parasite	Microbiology/Virology; Others
	Piperonyl butoxide (Pyrenone 606) 是黄樟素的半合成衍生物, 用作农药制剂的一个组成部分, 它是杀虫剂增效剂。
T12285	Ebopiprant OBE022,OBE-022	Others	Others
	Ebopiprant (OBE022) 是一个可口服且具有选择性和高效性的前列腺素 F2α (PGF2α) 受体拮抗剂，干扰 PGF0126α 与 FPR 的结合，可用于研究肥胖。
T12481	Pipecuronium bromide RGH-1106	AChR	Neuroscience
	Pipecuronium bromide (RGH-1106)是一种具有选择性和有效性的 nAChR 拮抗剂，也可当作一种非去极化甾体神经肌肉阻滞剂，可使肌肉松弛，常与抗生素一起使用。
T64319	4-benzyloxycarbonylamino-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester	Others	Others
	4-benzyloxycarbonylamino-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester 是一种生物活性化合物，可作为中间体用于多种化合物的合成。
T7555	Piperidolate hydrochloride	AChR	Neuroscience
	Piperidolate hydrochloride 是一种抗毒蕈碱药，可抑制乙酰胆碱引起的异常活性，能抑制大鼠和狗的肠痉挛。
T0280	Spiperone 螺哌隆,Spiroperidol,Spiropitan	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Spiperone (Spiropitan) 是多巴胺 D2、血清素5-HT1A 和血清素5-HT2A 拮抗剂。它是广泛使用的药理学工具。它具有研究神经系统疾病的潜力。
T20460	Piperonyl acetone 胡椒基丙酮,NSC405365,NSC 405365,NSC-405365	Others	Others
	Piperonyl acetone (NSC-405365) 是一种食品添加剂，用于食用调味料。
T12533	Piperylone PR66	Others	Others
	Piperylone (PR66) 具有具有抗痉挛、镇痛、抗炎和解热活性。
T1566	Aripiprazole 阿立哌唑,OPC-14597	5-HT Receptor	GPCR/G Protein; Neuroscience
	Aripiprazole (OPC-14597) 是血清素受体 5-HT1A 和多巴胺 D2 受体的部分激动剂，还用作突触后拮抗剂和血清素受体 5-HT2A 的拮抗剂。
T67957	Pipoxizine	Others	Others
	Pipoxizine 对组胺所致的支气管收缩具有拮抗作用，可用于研究哮喘疾病。

化合物

H-D-Phe-Pip-Arg-pNA dihydrochloride

Cat.No: T40711

Synonym: S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride

Target: Others

Cat.No: T9126

Target: Others

H-D-Phe-Pip-Arg-pNA hydrochloride

Cat.No: T39066

Synonym: S-2238 hydrochloride,H-D-Phe-Pip-Arg-pNA hydrochloride

H-D-Phe-Pip-Arg-pNA acetate

Cat.No: T38542

Synonym: H-D-Phe-Pip-Arg-pNA acetate,S-2238 acetate

(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH

Cat.No: T39494

Synonym: VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH,(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH

Target: Others

Pip-alkyne-Ph-COOCH3

Cat.No: T18545

Target: Others

Cat.No: T84768

Synonym: EA-PIP

Target: Others

Boc-Pip-alkyne-Ph-COOH

Cat.No: T17689

Target: Others

Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride

Cat.No: T38795

H-D-Phe-Pip-Arg-pNA

Cat.No: T34462

Synonym: S2238,S 2238,S-2238

Anti-PIP Monoclonal Antibody-APC

Cat.No: TMAZ-0234A

Anti-PIP Monoclonal Antibody-AF555

Cat.No: TMAZ-0234A5

Anti-PIP Monoclonal Antibody-PE

Cat.No: TMAZ-0234P

Anti-PIP Monoclonal Antibody-Biotin

Cat.No: TMAZ-0234B

Anti-PIP Monoclonal Antibody-AF647

Cat.No: TMAZ-0234A6

PIP4K-IN-a131

Cat.No: T39452

Synonym: PIP4K-IN-a131

Target: Others

Anti-PIP Monoclonal Antibody-AF488

Cat.No: TMAZ-0234A4

SP-346 nonapeptide

Cat.No: TP2409

Synonym: H-Val-Ser-Gln-Asn-Tyr-Pip-Ile-Val-Gln-NH2

Cat.No: TQ0292

Synonym: AAT-007,RQ-00000007,CJ-023423

Target: Prostaglandin Receptor

Pipendoxifene hydrochloride

Cat.No: T12482

Target: Estrogen Receptor/ERR

1-{1H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine 2HCl

Cat.No: T50034

Target: Others

Cat.No: T7405

Synonym: 二苯哌酯,哌立度酯

Target: AChR

Pipemidic acid

Cat.No: T0396

Synonym: 吡哌酸,Acido pipemidico

Target: Antibacterial, Antibiotic

Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Cat.No: T66256

Target: Factor Xa

Cat.No: T3965

Synonym: QAW039,NVP-QAW039,非维匹仑

Target: GPR, Prostaglandin Receptor

Aripiprazole Lauroxil

Cat.No: T14319

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T4570

Synonym: Vercyte,A-8103,Amedel,哌泊溴烷

Target: Others, DNA Alkylator/Crosslinker

3-Phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-tricyclo[3.3.1.13,7]decane-1-carboxamide

Cat.No: T8501

Target: Influenza Virus

Aspartyl-alanyl-diketopiperazine acetate

Cat.No: T10389L

Synonym: DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base)

Target: Others

4-(4-chlorophenyl)piperidin-4-ol

Cat.No: Fr13199

Target: Others

Piperonylonitrile

Cat.No: Fr13734

Synonym: 1,3-Benzodioxole-5-carbonitrile

Target: Others

BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride

Cat.No: T40111L

Target: PD-1/PD-L1

[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methanamine

Cat.No: T50061

Target: Others

N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine

Cat.No: T60231

Target: Others

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine

Cat.No: T77598

Synonym: (4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone

Target: Others

5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

Cat.No: T9361

Synonym: 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

Target: Others

Cat.No: T2664

Synonym: OC000459

Target: GPR, Prostaglandin Receptor

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one

Cat.No: T77687

Target: Others

2-(2,6-dioxopiperidin-3-yl)-4-((7-hydroxyheptyl)oxy)isoindoline-1,3-dione

Cat.No: T9385

Target: Others

1-(4-Carbethoxyphenyl)-piperazin

Cat.No: T9435

Target: Others

Piperonyl butoxide

Cat.No: T0727

Synonym: Pyrenone 606,ENT-14250,Ethanol butoxide,Butacide,增效醚

Target: Others, Parasite

Cat.No: T12285

Synonym: OBE022,OBE-022

Target: Others

Pipecuronium bromide

Cat.No: T12481

Synonym: RGH-1106

Target: AChR

4-benzyloxycarbonylamino-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester

Cat.No: T64319

Target: Others

Piperidolate hydrochloride

Cat.No: T7555

Target: AChR

Cat.No: T0280

Synonym: 螺哌隆,Spiroperidol,Spiropitan

Target: Dopamine Receptor

Piperonyl acetone

Cat.No: T20460

Synonym: 胡椒基丙酮,NSC405365,NSC 405365,NSC-405365

Target: Others

Cat.No: T12533

Synonym: PR66

Target: Others

Cat.No: T1566

Synonym: 阿立哌唑,OPC-14597

Target: 5-HT Receptor

Cat.No: T67957

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T19458	N-Hydroxypipecolic acid 1-Hydroxy-2-piperidinecarboxylic acid,NHP	Others	Others
	N-Hydroxypipecolic acid (NHP) 是植物代谢产物和系统性获得性抗性调节剂，可与免疫信号水杨酸协调建立系统性获得性抗性，诱导系统获得性耐药对细菌和卵菌感染。它在植物叶片中系统地积累，以应对病原菌的侵袭。
T6947	Piperlongumine PPLGM,荜茇酰胺,Piplartine	Apoptosis; ERK; Ferroptosis; Reactive Oxygen Species; ROS; Antibacterial; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology; NF-κB
	Piperlongumine (Piplartine) 属于生物碱类天然产物，具有抗肿瘤、抗炎、抗氧化、抗血管生成等生物活性。Piperlongumine 可以增强 ROS 水平，诱导肿瘤细胞凋亡。
T29756	1-piperoylpiperidine AI3 01439,胡椒碱,AI3-01439,AI 3-01439,piperine	Others	Others
	1-piperoylpiperidine (AI3-01439) 是一种生化物质。
TN6110	4,5-Dihydropiperlonguminine 二氢荜茇明宁碱,Dihydropiperlonguminine	Parasite	Microbiology/Virology
	4,5-Dihydropiperlonguminine (Dihydropiperlonguminine) 是一种从 Piper tuberculatum Jacq 的种子中分离出来的小分子化合物，具有杀虫和潜在的镇痛活性。
T3002	Piperine 胡椒碱,1-Piperoylpiperidine,Bioperine	P450; Endogenous Metabolite; P-gp; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Piperine (Bioperine) 是从胡椒中分离的一种生物碱，可以抑制P-糖蛋白和 CYP3A4 的活性，在HeLa 细胞中的IC50值为61.94±0.054 μg/mL。它已用于研究治疗多发性骨髓瘤和吞咽障碍的试验。
T4819	Pipecolic acid DL-哌啶甲酸,(±)-Piperidine-2-carboxylic acid,呢可酸,2-Piperidinecarboxylic acid,Pipecolinic acid,Homoproline	Others; Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology; Others
	Pipecolic acid (2-Piperidinecarboxylic acid) 是一种赖氨酸代谢物，是许多微生物次级代谢物的重要前体，可用作吡哆醇依赖性癫痫的诊断标记。
T13495	3-Amino-2-piperidinone Cyclo-ornithine	Endogenous Metabolite	Metabolism
	3-Amino-2-piperidinone 是来自生物体的代谢物，可用作环状鸟氨酸类似物。
T2937	4'-Demethylepipodophyllotoxin 4'-DMEP,4-Demethylepipodophyllotoxin,4'-脱甲基表鬼臼毒素,4'-去甲基表鬼臼毒素,DMEP,4'-O-demethylepipodophyllotoxin	Microtubule Associated	Cytoskeletal Signaling
	4'-Demethylepipodophyllotoxin (DMEP) 是一种有效的微管组装抑制剂。
TN7041	(-)-Epipodophyllotoxin	Apoptosis	Apoptosis
	(-)-Epipodophyllotoxin 是一种从八角莲中分离的癌细胞抗增殖剂，在 HeLa 细胞和 MCF-7 细胞中的GI50值分别为 0.36 和 0.24 μM。它可在体外抑制有丝分裂纺锤体组装。
T0345	Estropipate 雌酮硫酸酯哌嗪,Piperazine estrone sulfate,Pipestrone,Estrone sulfate piperazine salt	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Estropipate (Piperazine estrone sulfate) 是一种由硫酸雌酮和哌嗪组成的天然雌激素物质。
TN2085	Piperlonguminine	Anti-infection; Antibacterial; Antifungal	Microbiology/Virology
	Piperlonguminine 是一种从 Piper 中分离出的生物碱酰胺。它具有多种生物活性，如神经保护、抗炎、抗肿瘤、抗血小板、抗黑素生成、抗真菌和抗菌活性。
T13634	D-Pipecolinic acid (R)-Piperidine-2-carboxylic acid	Endogenous Metabolite	Metabolism
	D-Pipecolinic acid ((R)-Piperidine-2-carboxylic acid) 是一种存在于人体生物液体中的正常人体代谢物。
T9425	Epipinoresinol-4'-O-β-D-glucoside	Others	Others
	Simplocosin 是一种葡萄糖苷类化合物。
T5786	TETRAHYDROPIPERINE 四氢胡椒碱,Cosmoperine	P450; TRP/TRPV Channel	Membrane transporter/Ion channel; Metabolism
	Tetrahydropiperine (Cosmoperine) 是胡椒碱的环己基类似物，也是一种天然芳基戊酰胺，从Piper longum 分离得到。它对细胞色素 P450 (CYP) 同工型 CYP1A1/芳基烃羟化酶 (AHH；IC50=23 µM)具有抑制作用。
T4762	L-Pipecolic acid L-哌啶酸,L-Homoproline,H-HoPro-OH	Endogenous Metabolite	Metabolism
	L-Pipecolic acid (L-Homoproline) 是赖氨酸的分解产物，它能在患有常染色体遗传性疾病的婴儿体液中积累，比如新生儿肾上腺机能障碍， Zellweger 综合征等。
T8256	piperitone 胡椒酮,3甲基-6-(1-甲基乙基)-2-环己烯-1-酮	Others	Others
	Piperitone 是强大的驱虫剂和抗食欲剂。它对 Cymbopogon schoenanthus(C. schoenanthus) 成虫、新产卵和新生幼虫有很大的毒性。
TN6848	Piperonylic acid 胡椒酸,2H-1,3-benzodioxole-5-carboxylic acid	P450	Metabolism
	Piperonylic acid (2H-1,3-benzodioxole-5-carboxylic acid) 是一种具有亚甲二氧基活性的天然分子，与反式肉桂酸结构相似，可作为选择性反式肉桂酸 4-羟化酶的灭活剂。
T7646	Alloepipregnanolone	Endogenous Metabolite	Metabolism
	Alloepipregnanolone 是具有促进安定和睡眠的孕酮，可干扰乙醇抗焦虑作用的快速耐受。
TN2086	Piperlotine A	Antibacterial	Microbiology/Virology
	Piperlotine A 是一种可从罗洛胡椒中提取得到的生物碱，具有抗血小板聚集活性。Piperlotine A 在体外试验中显示出对结核分枝杆菌的抑制作用，MIC 值为 50 ug/mL。
TN1164	1-(3,4-Dimethoxycinnamoyl)piperidine	Others	Others
	1-(3,4-Dimethoxycinnamoyl)piperidine is a natural product
TN6804	Piperolein A
	Piperolein A is a natural product.
TN2758	2-Ethyl-2,6,6-trimethylpiperidin-4-one	Others	Others
	2-Ethyl-2,6,6-trimethylpiperidin-4-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2758，CAS号为 133568-79-3。
TN3045	4'-Hydroxypiptocarphin A	Others	Others
	4'-Hydroxypiptocarphin A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3045，CAS号为 103994-39-4。
T79951	Piperkadsin A	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Piperkadsin A作为一种ROS抑制剂，能够有效地抑制PMA诱导的人多形核中性粒细胞中ROS的生成，其IC50值为4.3 μM。
TN2922	3'-Demethoxypiplartine	Others	Others
	3'-Demethoxypiplartine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2922，CAS号为 130263-10-4。
TN2413	Diacetylpiptocarphol	Others	Others
	Diacetylpiptocarphol has antiplasmodial activity
TN2617	13-O-Ethylpiptocarphol	Others	Others
	13-O-Ethylpiptocarphol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2617，CAS号为 202522-40-5。
T19457	N-Hydroxypipecolic acid potassium NHP potassium,1-Hydroxy-2-piperidinecarboxylic acid potassium	Others	Others
	N-Hydroxypipecolic acid potassium is a metabolite of plant and a systemic acquired resistance (SAR) regulator.
TN2084	Piperitol	Others	Others
	Piperitol has in vitro antioxidant potential, it also exhibits a stronger CNS depressant effect than that of M. rotundifolia.
TN4798	Piptocarphin A	Others	Others
	Piptocarphin A shows strong cytotoxic activity against mouse lymphoid tumor cell line P388 with the IC(50) value of 0.77 microM.
T81456	Piperlactam S
	Piperlactam S, 分离自Piper kadsura，是一种用于慢性炎症研究的活性化合物。
TN7551	Piperitenone NSC 667470	Others	Others
	Piperitenone, a monoterpene identified in various plants, exhibits antioxidant activity and inhibits the peroxidation of linoleic acid.
TN2087	Piperlotine C	PAFR	GPCR/G Protein
	Piperlotine C shows potent antiplatelet aggregation activity.
TN1612	(+)-Epipinoresinol	Others	Others
	(+)-Epipinoresinol is a natural product
TN6799	Epiprogoitrin 表原告依春,epi-Progoitrin	Others	Others
	Epiprogoitrin (epi-Progoitrin) 是一种硫代葡萄糖苷，来自于Crambe abyssinica 种子。
TN3975	Epipterosin L 2'-O-glucoside	Others	Others
	Epipterosin L 2'-O-glucoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3975，CAS号为 61117-89-3。
TN1613	(-)-Epipinoresinol	Others	Others
	(-)-Epipinoresinol is a natural product
T66133	2-Piperidone	Others	Others
	2-Piperidone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T66133，CAS号为 675-20-7。
TN6126	Pipoxide chlorohydrin
	Pipoxide chlorohydrin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6126，CAS号为 29228-15-7。
TN4825	Prenylpiperitol	Others	Others
	Prenylpiperitol是一种天然产物，属于芸香科石南芸木属，其产品编号为 TN4825，CAS号为 157659-20-6。Prenylpiperitol可用作对照参考。
TN4797	Piperolactam C	PAFR; Antifection	GPCR/G Protein; Microbiology/Virology
	Piperolactam C possesses anti-platelet aggregation activity in vitro. It can inhibit the growth of the fungi Cladosporium sphaerospermum and C. cladosporioides.
TN4796	Piperlotine D	PAFR	GPCR/G Protein
	Piperlotine D shows potent antiplatelet aggregation activity.
TN3011	4,5-Diepipsidial A	Others	Others
	4,5-Diepipsidial A 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3011，CAS号为 1219603-97-0。
TN4799	Piptocarphin F	Others	Others
	Piptocarphin F shows strong cytotoxic activities against mouse lymphoid tumor cell line P388. It also shows cytotoxic activity (IC50 3.87-12.5 umol/L) against the human leukemic cell line HL-60.
T83445	16-Epipyromesaconitine
	16-Epipyromesaconitine为通过Mesaconitine热解产生的天然产物。
TN1357	Acetylepipodophyllotoxin	Others	Others
	Acetylepipodophyllotoxin has insecticidal activity.
TMA0098	3-Chloro-4-hydroxypiperidin-2-one	Others	Others
	3-Chloro-4-hydroxypiperidin-2-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TMA0098，CAS号为 174204-83-2。
TN4795	Piperenone	PAFR	GPCR/G Protein
	Piperenone is an insect antifeeding substance. It has anti-platelet-activating factor(PAF) activities, is a PAF-acether antagonist.
T79979	Methyl piperate	Monoamine Oxidase	Neuroscience
	Methylpiperate，一种胡椒碱类生物碱，展现出显著的MAO抑制活性(IC50 3.6 μM)。该化合物对MAO-B的选择性抑制作用(IC50 1.6 μM)优于对MAO-A(IC50 27.1 μM)，因此可用于治疗精神障碍。
TN3022	4'-Demethoxypiperlotine C	Others	Others
	4'-Demethoxypiperlotine C 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3022，CAS号为 807372-38-9。
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天然产物

N-Hydroxypipecolic acid

Cat.No: T19458

Synonym: 1-Hydroxy-2-piperidinecarboxylic acid,NHP

Target: Others

Piperlongumine

Cat.No: T6947

Synonym: PPLGM,荜茇酰胺,Piplartine

Target: Apoptosis, ERK, Ferroptosis, Reactive Oxygen Species, ROS, Antibacterial, Autophagy

1-piperoylpiperidine

Cat.No: T29756

Synonym: AI3 01439,胡椒碱,AI3-01439,AI 3-01439,piperine

Target: Others

4,5-Dihydropiperlonguminine

Cat.No: TN6110

Synonym: 二氢荜茇明宁碱,Dihydropiperlonguminine

Target: Parasite

Cat.No: T3002

Synonym: 胡椒碱,1-Piperoylpiperidine,Bioperine

Target: P450, Endogenous Metabolite, P-gp, Autophagy

Pipecolic acid

Cat.No: T4819

Synonym: DL-哌啶甲酸,(±)-Piperidine-2-carboxylic acid,呢可酸,2-Piperidinecarboxylic acid,Pipecolinic acid,Homoproline

Target: Others, Endogenous Metabolite, Antibacterial

3-Amino-2-piperidinone

Cat.No: T13495

Synonym: Cyclo-ornithine

Target: Endogenous Metabolite

4'-Demethylepipodophyllotoxin

Cat.No: T2937

Synonym: 4'-DMEP,4-Demethylepipodophyllotoxin,4'-脱甲基表鬼臼毒素,4'-去甲基表鬼臼毒素,DMEP,4'-O-demethylepipodophyllotoxin

Target: Microtubule Associated

(-)-Epipodophyllotoxin

Cat.No: TN7041

Target: Apoptosis

Cat.No: T0345

Synonym: 雌酮硫酸酯哌嗪,Piperazine estrone sulfate,Pipestrone,Estrone sulfate piperazine salt

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Piperlonguminine

Cat.No: TN2085

Target: Anti-infection, Antibacterial, Antifungal

D-Pipecolinic acid

Cat.No: T13634

Synonym: (R)-Piperidine-2-carboxylic acid

Target: Endogenous Metabolite

Epipinoresinol-4'-O-β-D-glucoside

Cat.No: T9425

Target: Others

TETRAHYDROPIPERINE

Cat.No: T5786

Synonym: 四氢胡椒碱,Cosmoperine

Target: P450, TRP/TRPV Channel

L-Pipecolic acid

Cat.No: T4762

Synonym: L-哌啶酸,L-Homoproline,H-HoPro-OH

Target: Endogenous Metabolite

Cat.No: T8256

Synonym: 胡椒酮,3甲基-6-(1-甲基乙基)-2-环己烯-1-酮

Target: Others

Piperonylic acid

Cat.No: TN6848

Synonym: 胡椒酸,2H-1,3-benzodioxole-5-carboxylic acid

Target: P450

Alloepipregnanolone

Cat.No: T7646

Target: Endogenous Metabolite

Piperlotine A

Cat.No: TN2086

Target: Antibacterial

1-(3,4-Dimethoxycinnamoyl)piperidine

Cat.No: TN1164

Target: Others

Cat.No: TN6804

2-Ethyl-2,6,6-trimethylpiperidin-4-one

Cat.No: TN2758

Target: Others

4'-Hydroxypiptocarphin A

Cat.No: TN3045

Target: Others

Piperkadsin A

Cat.No: T79951

Target: Reactive Oxygen Species

3'-Demethoxypiplartine

Cat.No: TN2922

Target: Others

Diacetylpiptocarphol

Cat.No: TN2413

Target: Others

13-O-Ethylpiptocarphol

Cat.No: TN2617

Target: Others

N-Hydroxypipecolic acid potassium

Cat.No: T19457

Synonym: NHP potassium,1-Hydroxy-2-piperidinecarboxylic acid potassium

Target: Others

Cat.No: TN2084

Target: Others

Piptocarphin A

Cat.No: TN4798

Target: Others

Piperlactam S

Cat.No: T81456

Cat.No: TN7551

Synonym: NSC 667470

Target: Others

Piperlotine C

Cat.No: TN2087

Target: PAFR

(+)-Epipinoresinol

Cat.No: TN1612

Target: Others

Cat.No: TN6799

Synonym: 表原告依春,epi-Progoitrin

Target: Others

Epipterosin L 2'-O-glucoside

Cat.No: TN3975

Target: Others

(-)-Epipinoresinol

Cat.No: TN1613

Target: Others

Cat.No: T66133

Target: Others

Pipoxide chlorohydrin

Cat.No: TN6126

Prenylpiperitol

Cat.No: TN4825

Target: Others

Piperolactam C

Cat.No: TN4797

Target: PAFR, Antifection

Piperlotine D

Cat.No: TN4796

Target: PAFR

4,5-Diepipsidial A

Cat.No: TN3011

Target: Others

Piptocarphin F

Cat.No: TN4799

Target: Others

16-Epipyromesaconitine

Cat.No: T83445

Acetylepipodophyllotoxin

Cat.No: TN1357

Target: Others

3-Chloro-4-hydroxypiperidin-2-one

Cat.No: TMA0098

Target: Others

Cat.No: TN4795

Target: PAFR

Methyl piperate

Cat.No: T79979

Target: Monoamine Oxidase

4'-Demethoxypiperlotine C

Cat.No: TN3022

Target: Others

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01916	PIP Protein, Human, Recombinant (His) gp17,Secretory actin-binding protein,Gross cystic disease fl...	Human	E. coli
	PIP Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00978	PIP4K2A Protein, Human, Recombinant (His) Diphosphoinositide kinase 2-α,PtdIns(5)P-4-kinase isoform 2-...	Human	HEK293 Cells
	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PIP4K2A) is a member of the phosphatidylinositol-4-phosphate 5-kinase family. It contains 1 PIPK domain and is expressed ubiquitously, with high levels in the brain. It catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). It may exert its function by regulating the levels of PtdIns5P, which functions in the...
TMPH-01858	PIP4K2B Protein, Human, Recombinant (His) Diphosphoinositide kinase 2-beta,Phosphatidylinositol 5-phos...	Human	E. coli
	PIP4K2B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 53.3 kDa and the accession number is P78356.
TMPY-00023	Epiphycan Protein, Human, Recombinant (His) epiphycan,DSPG3,Pg-Lb,PGLB,SLRR3B	Human	HEK293 Cells
	Epiphycan Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.1 kDa and the accession number is AAH30958.1.

重组蛋白

PIP Protein, Human, Recombinant (His)

Cat.No: TMPH-01916

Species: Human

Expression System: E. coli

PIP4K2A Protein, Human, Recombinant (His)

Cat.No: TMPJ-00978

Species: Human

Expression System: HEK293 Cells

PIP4K2B Protein, Human, Recombinant (His)

Cat.No: TMPH-01858

Species: Human

Expression System: E. coli

Epiphycan Protein, Human, Recombinant (His)

Cat.No: TMPY-00023

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0232	Piperacillin-d5 (N-ethyl-d5)
	Piperacillin-d5 (N-ethyl-d5) 是 Piperacillin 的氘代化合物。Piperacillin 的 CAS 号为 61477-96-1。Piperacillin 是半合成青霉素，可以作用于革兰氏阳性和革兰氏阴性需氧和厌氧菌。与其他青霉素相比，它对产生 β-内酰胺酶的菌类表现出更强的活性。
T10611	Brexpiprazole S-oxide D8 DM-3411 D8	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole. Brexpiprazole is a partial agonist of human 5-HT1A and dopamine receptors (Kis: 0.12 nM and 0.3 nM).
T10368	Aripiprazole (D8) OPC-14597 D8	Others	Others
	Aripiprazole D8 (OPC-14597 D8) is the deuterium-labeled Aripiprazole. Aripiprazole is a human 5-HT1A receptor partial agonist (Ki: 4.2 nM).
T10610	Brexpiprazole-d8 OPC-34712 D8	Others	Others
	Brexpiprazole D8 (OPC-34712 D8) is a deuterium-labeled Brexpiprazole. Brexpiprazole is a partial agonist of human 5-HT1A and dopamine receptors (Ki: 0.12 nM and 0.3 nM).
TMIH-0438	Piperacillin-d5
	Piperacillin-d5 是 Piperacillin 的氘代化合物。Piperacillin 的 CAS 号为 61477-96-1。Piperacillin 是半合成青霉素，可以作用于革兰氏阳性和革兰氏阴性需氧和厌氧菌。与其他青霉素相比，它对产生 β-内酰胺酶的菌类表现出更强的活性。
TMIJ-0112	Aripiprazole-d8
	Aripiprazole-d8 是 Aripiprazole 的氘代化合物。Aripiprazole 的 CAS 号为 129722-12-9。Aripiprazole 是血清素受体 5-HT1A 和多巴胺 D2 受体的部分激动剂，还用作突触后拮抗剂和血清素受体 5-HT2A 的拮抗剂。
TMIJ-0335	Dehydro aripiprazole-d8
	Dehydro aripiprazole-d8 是 Dehydro aripiprazole 的氘代化合物。Dehydro aripiprazole 的 CAS 号为 129722-25-4。Dehydroaripiprazole 是 Aripiprazole 的活性代谢产物，具有抗精神病活性。Aripiprazole 是也一种抗精神病药。

同位素标记化合物

Piperacillin-d5 (N-ethyl-d5)

Cat.No: TMIJ-0232

Brexpiprazole S-oxide D8

Cat.No: T10611

Synonym: DM-3411 D8

Target: Dopamine Receptor, 5-HT Receptor

Aripiprazole (D8)

Cat.No: T10368

Synonym: OPC-14597 D8

Target: Others

Brexpiprazole-d8

Cat.No: T10610

Synonym: OPC-34712 D8

Target: Others

Piperacillin-d5

Cat.No: TMIH-0438

Aripiprazole-d8

Cat.No: TMIJ-0112

Dehydro aripiprazole-d8

Cat.No: TMIJ-0335

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