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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1432 |
Phenylbutazone
Butazolidine,保泰松 |
COX | Immunology/Inflammation; Neuroscience |
Phenylbutazone (Butazolidine) 是是非甾体类抗炎药,前列腺素 H 合酶过氧化物酶的还原辅助因子,可诱导肌肉盲样蛋白 1 表达,有用于强直性脊柱炎的研究潜力。 | |||
T69926 |
APHS
|
Others | Others |
APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1. | |||
T39152 |
4-Hydroxyphenylbutazone
|
Others | Others |
4-Hydroxyphenylbutazone, a metabolite of Phenylbutazone, functions as an effective reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) known for its efficiency in this role. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01736 |
COX-2 Protein, Human, Recombinant (His)
GRIPGHS,PHS-2,hCox-2,COX-2,PGHS-2,prostaglandin-end... |
Human | Baculovirus Insect Cells |
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS2 is overexpressed in many cancers. The overexpression of PTGS2 along with increased angiogenesis and GLUT-1 expression ... | |||
TMPJ-01043 |
PHS Protein, Human, Recombinant (His)
4-Alpha-Hydroxy-Tetrahydropterin Dehydratase,Pterin-4-α-Carb... |
Human | E. coli |
Pterin-4-α-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-α-Carbinolamine Dehydratase Family. PCBD1 is involved in Tetrahydrobiopterin biosynthesis. It seems to prevent the formation of 7-Pterins and accelerate the formation of Quinonoid-BH2. Furthermore, PCBD1 regulates the homodimerization of the transcription factor Hepatocyte Nuclear Factor 1 (HNF1) and enhances its transcriptional activity. Defects in PCBD1 are the cause of BH4-Deficient Hyperphenylalaninemia Type ... | |||
TMPH-02072 |
SEPHS2 Protein, Human, Recombinant (His & Myc)
Selenide, water dikinase 2,Selenophosphate synthase 2,SE... |
Human | E. coli |
SEPHS2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPJ-00988 |
SEPHS1 Protein, Human, Recombinant (His)
water dikinase 1,SELD,Selenophosphate synthase 1,SEPHS |
Human | HEK293 Cells |
Selenophosphate synthetase 1 (SEPHS1) belongs to the selenophosphate synthase 1 family, Class II subfamily. It has four different isoforms by alternative splicing. Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased, which Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. SEPHS1 can be activated by phosphate ions and by potassium ions. It can synthesize synthesizes selenophosphate from selenide and ATP.... | |||
TMPH-01751 |
Nephrin/NPHS1 Protein, Human, Recombinant (His)
Nephrin,Renal glomerulus-specific cell adhesion receptor,N |
Human | E. coli |
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion. Nephrin/NPHS1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.1 kDa and the accession number is O60500. |