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Targets Recommended: COX

3

抑制剂 & 化合物

5

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T1432 Phenylbutazone

Butazolidine,保泰松

COX Immunology/Inflammation; Neuroscience
Phenylbutazone (Butazolidine) 是是非甾体类抗炎药,前列腺素 H 合酶过氧化物酶的还原辅助因子,可诱导肌肉盲样蛋白 1 表达,有用于强直性脊柱炎的研究潜力。
T69926 APHS

Others Others
APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.
T39152 4-Hydroxyphenylbutazone

Others Others
4-Hydroxyphenylbutazone, a metabolite of Phenylbutazone, functions as an effective reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) known for its efficiency in this role.

化合物

Phenylbutazone
Cat.No: T1432
Synonym: Butazolidine,保泰松
Target: COX
APHS
Cat.No: T69926
Synonym:
Target: Others
4-Hydroxyphenylbutazone
Cat.No: T39152
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-01736 COX-2 Protein, Human, Recombinant (His)

GRIPGHS,PHS-2,hCox-2,COX-2,PGHS-2,prostaglandin-end...

Human Baculovirus Insect Cells
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS2 is overexpressed in many cancers. The overexpression of PTGS2 along with increased angiogenesis and GLUT-1 expression ...
TMPJ-01043 PHS Protein, Human, Recombinant (His)

4-Alpha-Hydroxy-Tetrahydropterin Dehydratase,Pterin-4-α-Carb...

Human E. coli
Pterin-4-α-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-α-Carbinolamine Dehydratase Family. PCBD1 is involved in Tetrahydrobiopterin biosynthesis. It seems to prevent the formation of 7-Pterins and accelerate the formation of Quinonoid-BH2. Furthermore, PCBD1 regulates the homodimerization of the transcription factor Hepatocyte Nuclear Factor 1 (HNF1) and enhances its transcriptional activity. Defects in PCBD1 are the cause of BH4-Deficient Hyperphenylalaninemia Type ...
TMPH-02072 SEPHS2 Protein, Human, Recombinant (His & Myc)

Selenide, water dikinase 2,Selenophosphate synthase 2,SE...

Human E. coli
SEPHS2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPJ-00988 SEPHS1 Protein, Human, Recombinant (His)

water dikinase 1,SELD,Selenophosphate synthase 1,SEPHS

Human HEK293 Cells
Selenophosphate synthetase 1 (SEPHS1) belongs to the selenophosphate synthase 1 family, Class II subfamily. It has four different isoforms by alternative splicing. Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased, which Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. SEPHS1 can be activated by phosphate ions and by potassium ions. It can synthesize synthesizes selenophosphate from selenide and ATP....
TMPH-01751 Nephrin/NPHS1 Protein, Human, Recombinant (His)

Nephrin,Renal glomerulus-specific cell adhesion receptor,N

Human E. coli
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion. Nephrin/NPHS1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.1 kDa and the accession number is O60500.

重组蛋白

COX-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01736
Species: Human
Expression System: Baculovirus Insect Cells
PHS Protein, Human, Recombinant (His)
Cat.No: TMPJ-01043
Species: Human
Expression System: E. coli
SEPHS2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02072
Species: Human
Expression System: E. coli
SEPHS1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00988
Species: Human
Expression System: HEK293 Cells
Nephrin/NPHS1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01751
Species: Human
Expression System: E. coli
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