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Cat. No. | Product Name | Target | Signaling Pathways |
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T82485 |
ELAAWCRWGFLLALLPPGIAG
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ELAAWCRWGFLLALLPPGIAG (P5) 是源自大鼠HER2/neu蛋白的21个氨基酸长肽(氨基酸5-25)。此肽可诱导携带HER2阳性肿瘤小鼠中的细胞毒性T淋巴细胞(CTL)反应。 | |||
T82484 |
ELAAWCRWGFLLALLPPGIAG TFA
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ELAAWCRWGFLLALLPPGIAG TFA (P5) 是由大鼠HER2/neu蛋白衍生的21个氨基酸长的肽段(氨基酸序号5至25)。该化合物在携带HER2阳性肿瘤的小鼠模型中,能够诱发细胞毒性T淋巴细胞(CTL)的反应。 | |||
T36546 |
Prostaglandin I3 (sodium salt)
Prostaglandin I3 (sodium salt) |
Others | Others |
PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2. | |||
T76152 |
Glucose 6-phosphate isomerase
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Others | Others |
Glucose 6-phosphate isomeras (GPI) 葡萄糖 6-磷酸异构酶,即磷酸葡萄糖异构酶/磷酸葡萄糖异构酶 (PGI) 或磷酸己糖异构酶 (PHI),常用于生化研究。Glucose 6-phosphate isomeras 是一种高度保守的糖酵解酶和二聚酶。Glucose 6-phosphate isomeras 催化葡萄糖-6-磷酸异构成果糖-6-磷酸。 | |||
T84575 |
U-51605
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Others | Others |
U-51605, a stable analog of the endoperoxide prostaglandin H2 (PGH2), functions as an inhibitor with greater selectivity towards prostacyclin (PGI) synthase over thromboxane (TX) synthase. It also acts as a partial agonist at TP receptors. Studies show that at a concentration of 2.8 µM, U-51605 effectively inhibits PGI synthase in human foreskin fibroblasts, while a concentration of 5.6 µM is required to inhibit human platelet TX synthase. Furthermore, U-51605, at up to 1 µM, decreases the relea... | |||
T78780 |
Anticancer agent 139
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Others | Others |
Anticanceragent 139(Compound 6h)展现了针对多种癌细胞株的抗癌效能。该化合物能够与Tubulin的Lys352残基发生π-阳离子相互作用。在对SNB-19、OVCAR-8和NCI-H460细胞株的测试中,Anticanceragent 139展现出较高的生长抑制率(PGI),数值分别为86.61、85.26和75.99。同时,该化合物对于HOP-62、SNB-75、ACHN、NCI/ADR-RES、786-O、A549/ATCC、HCT-116以及MDA-MB-231细胞株亦表现出中等的生长抑制作用,其PGI值分别为67.55、65.46、59.09、59.02、57.88、56.88、56.53和56.4、51.88。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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T10185 |
6-Phosphogluconic acid
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Others; Endogenous Metabolite | Metabolism; Others |
6-Phosphogluconic acid 是竞争性的磷酸葡萄糖异构酶抑制剂,对6-磷酸果糖和6-磷酸葡萄糖和的 Ki 分别为 42 μM 和 48 μM。它属于人内源性代谢物。 |