5
6
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T23142 |
PF9 tetrasodium salt
|
Others | Others |
GPR17 agonist | |||
T16491 |
PF-06446846 hydrochloride
|
Others | Others |
PF-06446846 hydrochloride 是一种口服活性高、高选择性PCSK9(前蛋白转化酶枯草杆菌蛋白酶/kexin 9 型)翻译抑制剂。它通过在密码子34附近诱导核糖体暂停来抑制PCSK9。 | |||
T67694 |
ZY-19489
|
Parasite | Microbiology/Virology |
ZY-19489是一种具有抗疟作用的化合物, 是一种潜在的单剂量根治性恶性疟原虫和间日疟原虫疟疾的药物,已获得美国 FDA 的孤儿药认定。 | |||
T72221 |
PF-06815345 hydrochloride
|
Others | Others |
PF-06815345 hydrochloride 是一款口服有效的PCSK9抑制剂,其IC50值为13.4 μM。在小鼠体内,能显著降低PCSK9水平。 | |||
T37800 |
PF-04449613
|
Others | Others |
PF-04449613 is a phosphodiesterase 9A (PDE9A) inhibitor (IC50= 22 nM).1It is selective for PDE9A over PDE1C (IC50= >1,000 nM), as well as over a variety of other PDEs, inhibiting PDE2-8, -10, and -11 activity by less than 30% in a panel of enzymes, ion channels, and transporters at 1 μM but does inhibit the human dopamine transporter (DAT; Ki= 293 nM). PF-04449613 (0.1-100 mg/kg, s.c.) increases cerebrospinal fluid (CSF) levels of cyclic GMP (cGMP) in rats. Subcutaneous administration of PF-0444... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00865 |
VEGF121 Protein, Human, Recombinant (His)
VEGFA,VEGF-A,Vascular permeability factor,VPF,血管内皮生... |
Human | HEK293 Cells |
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessel... | |||
TMPY-03698 |
VEGF121b Protein, Human, Recombinant
MVCD1,VEGF,VPF,vascular endothelial growth factor A |
Human | HEK293 Cells |
VEGF121b Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 34.10 kDa and the accession number is P15692-9. | |||
TMPH-00005 |
YAP1 Protein, Human, Recombinant (Isoform 9, His)
Protein yorkie homolog,YAP1,Yes-associated protein YAP65 hom... |
Human | P. pastoris (Yeast) |
YAP1 Protein, Human, Recombinant (Isoform 9, His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 56.4 kDa; 80 kDa, reducing conditions and the accession number is P46937-9. | |||
TMPK-00825 |
VEGF121 Protein, Human, Recombinant (His & Avi)
VPF,VEGF,VEGFA,VEGFMGC70609,血管内皮生长因子,MGC70... |
Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9. | |||
TMPK-00826 |
VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated
VAS,VEGFMGC70609,RP1-261G23.1,血管内皮生长因子,VEGFA,VP... |
Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9. | |||
TMPY-05268 |
Neurofascin Protein, Human, Recombinant (hFc), Biotinylated
NRCAML,neurofascin,NF |
Human | HEK293 Cells |
Neurofascin Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 130 kDa and the accession number is O94856-9. |