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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T70782 PF-05139962

Others Others
PF-05139962 is a novel potent mTOR inhibitor with excellent mTOR biochemical inhibition, cellular potency, kinase selectivity and in vitro ADME properties. PF-05139962 has pS473 and pS6 cellular IC50 = 48 and 6 nM respectively. PF-05139962 has great selectivity against other receptors and kinases. No genotoxicity was observed on this compound and no more than 25% inhibiton was observed for major CYP enzymes (3A4, 1A2, 2C9, 2D6) at 3 uM. This compound has LE = 0.35 and LipE up to 6.8 which is in ...
T70780 BW 737C89

Others Others
BW 737C89 is a highly potent dopamine D1 receptor antagonist; BW-737C is the (S)-isomer; BW-736C is the (R)-isomer.

化合物

PF-05139962
Cat.No: T70782
Synonym:
Target: Others
BW 737C89
Cat.No: T70780
Synonym:
Target: Others
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