2820
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9098 |
DMG-PEG 2000
DMG-PEG2000 |
Others | Others |
DMG-PEG 2000 (DMG-PEG2000) 可用于脂质纳米颗粒制备,用于口服质粒 DNA 的体内传递途径,提高纳米颗粒的黏液渗透性和传递效率。它也可用于 siRNA 转染的脂质体的制备,能够提高转染效率。 | |||
T17854 |
DSPE-PEG-OH (MW 2000)
|
Others; PROTAC Linker | Others; PROTAC |
DSPE-PEG-OH (MW 2000) 是一种基于 PEG 的 PROTAC 接头,可用于 PROTAC 的合成。 | |||
T17397 |
Amine-PEG-CH2COOH (MW 2000)
|
Others; PROTAC Linker | Others; PROTAC |
Amine-PEG-CH2COOH (MW 2000) 是一种基于 PEG 的 PROTAC 接头,可用于合成 PROTAC。 | |||
T17850 |
DSPE-PEG-Biotin (MW 2000)
|
PROTAC Linker | PROTAC |
DSPE-PEG-Biotin (MW 2000) 是一种基于 PEG 的 PROTAC 接头,可用于 PROTAC 的合成。 | |||
T24610 |
Pegamotecan
Prothecan,PEG-camptothecin,PEG-beta-CPT |
Topoisomerase | DNA Damage/DNA Repair |
Pegamotecan (PEG-camptothecin)是一种拓扑异构酶I(TOP1)抑制剂,具有抗癌活性,它可用于治疗食管癌、非小细胞肺癌和胰腺癌。 | |||
T74229 |
DSPE-PEG 2000
|
Others | Others |
DSPE-PEG 2000 是一种 PEG 脂质体,可用于形成胶束作为药物递送的纳米颗粒。 | |||
T18818 |
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
|
Others; E3 Ligase Ligand-Linker Conjugate | Others; PROTAC |
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物。它可用于 PROTAC 的合成分子。 | |||
T39427 |
Thalidomide-O-amido-PEG-C2-NH2
Thalidomide-O-amido-PEG-C2-NH2 |
Others | Others |
Thalidomide-O-amido-PEG-C2-NH2 is a synthesized conjugate formulation designed as an E3 ligase ligand-linker conjugate. It incorporates a cereblon ligand based on Thalidomide and a linker component commonly utilized in PROTAC technology. | |||
T13012 |
Stearyldiethanolamine
PEG-2 Stearamine,2,2'-(Octadecylazanediyl)diethanol,2,2'-(Octadecylimino)diethanol |
Others | Others |
Stearyldiethanolamine (2,2'-(Octadecylazanediyl)diethanol) 可用于抗菌无纺布和抗菌保鲜膜的研究。 | |||
T19506 |
PEG400
|
Others | Others |
PEG400 是一种强亲水性聚乙二醇,可作为多种物质的优良溶剂,广泛用于多种药物制剂中。 | |||
T17831 |
Dioxoisoindolin-O-PEG-OMe (MW 2000)
(1,3-dioxoisoindolin-2-yl)-O-PEG-OMe (MW 2000) |
Others | Others |
Dioxoisoindolin-O-PEG-OMe (MW 2000) is a polyethylene glycol (PEG) based PROTAC linker, which finds application in the synthesis of PROTACs[1]. | |||
T17830 |
Dioxoisoindolin-O-PEG-OH (MW 2000)
(1,3-dioxoisoindolin-2-yl)-O-PEG-OH (MW 2000) |
Others | Others |
Dioxoisoindolin-O-PEG-OH (MW 2000) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of PROTACs (proteolysis targeting chimeras)[1]. | |||
T40438 |
PEG-8 laurate
|
Others | Others |
PEG-8 laurate is a monofunctional surfactant and skin penetration enhancer. It disrupts the skin barrier and facilitates the formation of elastic vesicles when synthesized. | |||
T40094 |
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2,Cereblon Ligand-Linker Conjugates 12,E3LigaseLigand-LinkerConjugates23 |
Others | Others |
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate compound that combines a Thalidomide-based cereblon ligand and a linker, which is commonly utilized in PROTAC technology. This compound acts as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation. | |||
T16457 |
PEG3-methylamine
|
PROTAC Linker | PROTAC |
PEG3-methylamine 是一种属于 PEG 类的 PROTAC linker,可用于合成 PROTAC 分子。 | |||
T14250 |
Amino-PEG8-amine
|
Others | Others |
Amino-PEG8-amine 是一种以聚乙二醇为基础的 PROTAC 连接剂,可用于PROTACs 的合成,是一种含有两个氨基(NH2)基团的共轭PEG 衍生物。 | |||
T18137 |
m-PEG12-DBCO
|
PROTACs | PROTAC |
m-PEG12-DBCO 是一种属于 PEG 类的 PROTAC linker。 | |||
T17859 |
DSPE-PEG4-DBCO
|
PROTACs | PROTAC |
DSPE-PEG4-DBCO 是一种属于 PEG 类的 PROTAC linker。DSPE-PEG4-DBCO 可细胞成像和生物医学研究中用作生物材料。 | |||
T17595 |
Biotin-PEG8-amine
|
PROTACs | PROTAC |
Biotin-PEG8-amine 是一种属于 PEG 类的 PROTAC linker,可用于合成 PROTAC 分子。 | |||
T14264 |
Aminooxy-PEG3-azide
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
Aminooxy-PEG3-azide 是一种属于 PEG 类的 ADC linker,有三单元的 PEG,可用于合成抗体偶联活性分子 (ADC)。 | |||
T17791 |
DBCO-PEG3-NHS ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
DBCO-PEG3-NHS ester是一种可降解的 ADC linker,可用于合成抗体偶联活性分子 。 | |||
T16982 |
TAMRA-PEG3-Azide
|
PROTAC Linker | PROTAC |
TAMRA-PEG3-Azide 是一种 TAMRA 红色荧光染料连接剂,最大激发/发射波长为 553/575 nm。 | |||
T14450 |
Azido-PEG4-hydrazide
|
PROTACs | PROTAC |
Azido-PEG4-hydrazide 是一种属于 PEG 类的 PROTAC linker,可用于合成 PROTAC 分子。 | |||
T14271 |
Aminooxy-PEG4-alcohol
|
Others; PROTAC Linker; ADC Linker | Antibody-drug Conjugate/ADC Related; Others; PROTAC |
Aminooxy-PEG4-alcohol 既是不可裂解的 4 单元 PEG ADC linker,也是基于 PEG 的 PROTAC linker。 | |||
T15839 |
m-PEG12-amine
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
m-PEG12-amine是一种基于PEG的PROTAC连接器,同时也是一种在PROTACs[1]和抗体药物偶联物(ADCs)[2]的合成中使用的不可切割的12单位PEG ADC连接器。 | |||
T18996 |
GNF-2-PEG-acid
|
Others | Others |
GNF-2-PEG-acid is usually used as a fluorescent probe. | |||
T17395 |
Amine-PEG-CH2COOH (MW 5000)
|
Others | Others |
Amine-PEG-CH2COOH (MW 5000) is a polyethylene glycol (PEG) derivative employed as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1]. | |||
T38948 |
MS-PEG4-THP
|
PROTAC Linker | PROTAC |
MS-PEG4-THP 是PEG 类PROTAC linker,可用于合成 PROTAC 分子。 | |||
T18568 |
Propargyl-PEG11-methane
|
Others; PROTAC Linker | Others; PROTAC |
Propargyl-PEG11-methane 是 PEG 类 PROTAC linker。可用于合成 PROTAC 分子。 | |||
T17464 |
Azide-PEG12-alcohol
|
Others; PROTAC Linker | Others; PROTAC |
Azide-PEG12-alcohol 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17405 |
Amino-PEG12-acid
|
Others; PROTAC Linker | Others; PROTAC |
Amino-PEG12-acid 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T18106 |
m-PEG-OH (MW5000)
|
Others | Others |
m-PEG-OH (MW5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | |||
T14220 |
Amine-PEG3-Biotin
|
Others | Others |
Amine-PEG3-Biotin 可用作信号放大标记。 | |||
T15114 |
Diazo Biotin-PEG3-alkyne
Diazo Biotin-Alkyne |
PROTACs | PROTAC |
Diazo Biotin-PEG3-alkyne 是一种属于 PEG 类的 PROTAC linker,可用于合成 PROTAC 分子。 | |||
T17522 |
Azido-PEG9-azide
|
Others; PROTAC Linker | Others; PROTAC |
Azido-PEG9-azide 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17402 |
Amino-PEG10-acid
|
Others; PROTAC Linker | Others; PROTAC |
Amino-PEG10-acid 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17484 |
Azido-PEG12-acid
|
Others; PROTAC Linker | Others; PROTAC |
Azido-PEG12-acid 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T38888 |
Azide-PEG3-Desthiobiotin
Azide-PEG3-Desthiobiotin |
Others | Others |
Azide-PEG3-Desthiobiotin 是一种 属于 PEG 类的PROTAC linker,可用于合成 PROTAC 分子。 | |||
T74245 |
DSPE-PEG
|
Others | Others |
DSPE-PEG为磷脂-聚合物偶联物,在药物递送应用中有重要用途。该材料能作为纳米载体的基础,用以增强血液循环时间、稳定性及封装效率。 | |||
T39806 |
Pomalidomide 4'-PEG3-azide
Pomalidomide 4'-PEG3-azide |
Others | Others |
Pomalidomide 4'-PEG3-azide is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker conjugate that incorporates the cereblon ligand derived from Pomalidomide, along with a linker. This compound, Pomalidomide 4'-PEG3-azide, is utilized in the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3, developed through the PROTAC strategy, is an effective degrader of PARP1, derived from Rucaparib. | |||
T15976 |
Mal-PEG1-NHS ester
|
Others; PROTAC Linker; ADC Linker | Antibody-drug Conjugate/ADC Related; Others; PROTAC |
Mal-PEG1-NHS ester 是一种可裂解的基于 PEG 的 ADC 接头,用于合成抗体-药物偶联物。它也是基于 PEG 的 PROTAC 接头,可用于 PROTAC 的合成。 | |||
T17636 |
Bis-Tos-PEG7
|
Others; PROTAC Linker | Others; PROTAC |
Bis-Tos-PEG7 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T18153 |
m-PEG16-Br
|
Others; PROTAC Linker | Others; PROTAC |
m-PEG16-Br 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T16981 |
TAMRA-Azide-PEG-biotin
|
Others | Others |
TAMRA-Azide-PEG-biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T18566 |
Propargyl-PEG12-bromide
|
Others; PROTAC Linker | Others; PROTAC |
Propargyl-PEG12-bromide 是 PEG 类PROTAC linker,可用于合成 PROTAC 分子。 | |||
T18229 |
m-PEG9-SH
|
Others; PROTAC Linker | Others; PROTAC |
m-PEG9-SH 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T16437 |
PC Biotin-PEG3-alkyne
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
PC Biotin-PEG3-alkyne 是一种 ADC 连接剂,可裂解的 3 单元 PEG,还可以用于合成抗体药物共轭物 (ADC)。 | |||
T17492 |
Azido-PEG2-azide
|
Others; PROTAC Linker | Others; PROTAC |
Azido-PEG2-azide 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17408 |
Amino-PEG12-Boc
|
Others; PROTAC Linker | Others; PROTAC |
Amino-PEG12-Boc 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17406 |
Amino-PEG12-alcohol
|
Others; PROTAC Linker | Others; PROTAC |
Amino-PEG12-alcohol 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TC0022 |
Desoxypeganine
Deoxypeganine |
AChE | Neuroscience |
Desoxypeganine (Deoxypeganine) 是胆碱酯酶的抑制剂。它优先作用于丁酰胆碱酯酶,作为单胺氧化酶 A 而不是单胺氧化酶 B 的选择性抑制剂。它在酒精滥用的药理学治疗中的潜在用途,以减少酒精滥用者的渴望和抑郁,并且也可能有用作为戒烟辅助。 | |||
TN7232 |
Pegamine
|
||
pegamine 是一种在Peganum harmala 和Peganum nigellastrum 中发现的天然产品,是一种新型的生物碱。 | |||
TN6045 |
Spegatrine
|
||
Spegatrine is a natural product from Rauvolfia verticillata. | |||
T81529 |
Peganumine A
|
Others | Others |
Peganumine A,一种天然产物,源自Peganum harmala,具备对HL-60、MCF-7、PC-3、HepG2细胞线显示出细胞毒性作用,其IC50值依次为5.8、38.5、40.2、55.4 µM[1]< /sup>。 | |||
TN5881 |
4′-O-Isobutyroylpeguangxienin
|
||
4′-O-Isobutyroylpeguangxienin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5881,CAS号为 2188162-95-8。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04471 |
APEG1 Protein, Human, Recombinant (His)
SPEG complex locus,BPEG,SPEGalpha... |
Human | E. coli |
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. SPEG / APEG-1 contains two fibronectin type-III domains, nine Ig-like (immunoglobulin-like) domains, two protein kinase domains. Isoform 1 of SPEG is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 of SPEG is predominantly expre... |