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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37486 |
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC
|
Others | Others |
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is toxic to human umbilical vein endothelial cells (HUVECs) when used at a concentration of 100 μM. | |||
T38218 |
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC
|
Others | Others |
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC 是一种在生物膜中的磷脂,在 sn-1 和 sn-2 位置分别含有硬脂酸和二十二碳六烯酸。它已被用于研究脂膜的组织和动力学。在超氧化物歧化酶 1 突变体转基因小鼠肌萎缩性脊髓侧索硬化症(ALS)模型中1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC 的水平在疾病晚期会在 L5 前角下降。1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC 可用于研究生物膜。 | |||
T85064 |
1-1(Z)-Hexadecenyl-2-Palmitoyl-sn-glycero-3-PC
1-1(Z)-Hexadecenyl-2-Hexadecanoyl-sn-glycero-3-Phosphocholine,PC(P-16:0/16:0),C16(plasm)-16:0-PC,16:0p/16:0-PC,1-1(Z)-Hexadecenyl-2-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine |
Others | Others |
1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PC, a plasmalogen, appears in various rat tissues including the liver, heart, kidney, and both gluteus and soleus muscles, as well as visceral and subcutaneous adipose tissues. It serves in lipid bilayer synthesis to investigate how amphiphilic compounds, like lysophosphatidylcholine (1-palmitoyl-2-hydroxy-sn-glycero-3-PC) and lysoplasmenylcholine, influence membrane dynamics. | |||
T37485 |
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC
|
Others | Others |
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO). | |||
T84375 |
1-Palmitoyl-2-Linoleoyl-sn-glycero-3-PC
16:0-18:2 PC,1-Palmitoyl-2-Linoleoyl-sn-glycero-3-Phosphatidylcholine,PLPC |
Others | Others |
1-Palmitoyl-2-Linoleoyl-sn-glycero-3-phosphatidylcholine (PC) is a phospholipid characterized by the incorporation of palmitic (16:0) and linoleic (18:2) acids at the sn-1 and sn-2 positions, respectively. It is utilized in the creation of micelles, liposomes, and various artificial membranes, playing a significant role in research on lipid peroxidation. | |||
T85255 |
1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC
1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-Phosphocholine,PC(16:0/20:4),PAPC |
Others | Others |
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid found in biological membranes, featuring palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively. PAPC undergoes oxidation in vivo, producing derivatives that play roles in chronic inflammation and vascular disease. Additionally, PAPC has been utilized in the investigation of oxidized phospholipid signaling mechanisms. Notably, PAPC levels are diminished in isolated human multiple myeloma ce... | |||
T16961 |
Supinoxin
RX-5902 |
Apoptosis; DNA/RNA Synthesis | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Supinoxin (RX-5902) 是磷酸化 p68 RNA 解旋酶的强效口服活性抑制剂,是一种抗肿瘤试剂。它与 Y593 磷酸化的 p68 相互作用并减弱 β-catenin 的核穿梭性。它诱导细胞凋亡并抑制 TNBC 癌细胞系的生长,IC50的范围为 10 nM 至 20 nM。 | |||
T16996 |
TAS6417
|
Apoptosis; EGFR | Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
TAS6417 是一种高效的、具有口服活性的 EGFR 突变型抑制剂,可独特的结合到 EGFR 铰链区的 ATP 结合位点,其 IC50值为 1.1-8.0 nM。 | |||
T2490 |
Osimertinib
AZD-9291,Mereletinib,奥希替尼 |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Osimertinib (AZD-9291) 是一种 EGFR 三代抑制剂,抑制二代 EGFR 抑制剂产生的 T790M 耐药突变,具有不可逆性和口服活性。Osimertinib 具有抗肿瘤活性,用于治疗 EGFR 突变的非小细胞肺癌。 | |||
T3634 |
Osimertinib mesylate
甲磺酸奥希替尼,Mereletinib mesylate,奥希替尼甲磺酸盐,AZD-9291 mesylate |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Osimertinib mesylate (Mereletinib mesylate) 是一种不可逆的突变选择性 EGFR 抑制剂,对EGFRL858R 和EGFRL858R/T790M 的IC50值分别为 12 和 1 nM。 | |||
T64546 |
1-Stearoyl-2-myristoyl-sn-glycero-3-PC
|
Others | Others |
1-Stearoyl-2-myristoyl-sn-glycero-3-PC 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64546,CAS号为 20664-02-2。 | |||
T85003 |
1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC
PC(18:0/22:4) |
Others | Others |
1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC (PC(18:0/22:4)) 是一种抑制细胞周期蛋白依赖性激酶 (CDKs) 的化合物,能够诱导细胞凋亡 (apoptosis) 并阻止多种癌终细胞系的增殖。 | |||
T84612 |
1-O-hexadecyl-2-Eicosapentaenoyl-sn-glycero-3-PC
1-O-hexadecyl-2-Eicosapenaenoyl-sn-glycero-3-phosphocholine |
Others | Others |
"1-O-Hexadecyl-2-eicosapentaenoyl-sn-glycero-3-PC is a compound that results from the incorporation of eicosapentaenoic acid (EPA) into lyso-PAF C-16, a process demonstrated in neutrophils from monkeys and humans consuming a diet rich in fish oils. Furthermore, it functions as a precursor for PAF C-16 synthesis via the remodeling pathway." | |||
T84971 |
1-Stearoyl-2-Eicosapentaenoyl-sn-glycero-3-PC
1-Octadecanoyl-1-Eiocosapentaenoyl-sn-glycero-3-Phosphatidylcholine |
Others | Others |
1-Stearoyl-2-eicosapentaenoyl-sn-glycero-3-PC is a phospholipid comprising stearic acid and eicosapentaenoic acid at the sn-1 and sn-2 positions, respectively, identified in human red blood cells (RBCs). | |||
T84453 |
1-Palmitoyl-2-Lauroyl-sn-glycero-3-PC
1-Palmitoyl-2-Lauroyl-sn-glycero-3-Phosphatidylcholine |
Others | Others |
1-Palmitoyl-2-lauroyl-sn-glycero-3-PC (1,2-PLPC) is a phospholipid with palmitoyl (16:0) and lauryl (12:0) acyl chains at the sn-1 and sn-2 positions, respectively. This mixed-chain phosphatidylcholine aids in researching the role of chain-chain contact interactions in maintaining the structural stability of lipid membrane bilayers. | |||
T84611 |
1-O-hexadecyl-2-Arachidonoyl-sn-glycero-3-PC
Arachidonoyl PAF C-16 |
Others | Others |
1-O-Hexadecyl-2-arachidonoyl-sn-glycero-3-PC undergoes acylation through the action of CoA-independent transacylase, transforming lyso-PAF C-16 into this compound. It serves as the predominant precursor in the biosynthesis of PAF C-16 via the remodeling pathway. | |||
T85004 |
1-Palmitoyl-2-13(S)-HpODE-sn-glycero-3-PC
1-Palmitoyl-2-13(S)-HpODE-sn-glycerol-3-Phosphatidylcholine |
Others | Others |
1-Palmitoyl-2-13(S)-HpODE-sn-glycero-3-PC is a phospholipid featuring palmitic acid at the sn-1 position and 13(S)-HpODE at the sn-2 position. | |||
T130784 |
6-(1-Hydroxypentyl)-4-methoxy-2H-pyran-2-one. PC
|
Others | Others |
6-(1-Hydroxypentyl)-4-methoxy-2H-pyran-2-one. PC 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T130784。 | |||
T60812 |
Cathepsin X-IN-1
|
Cysteine Protease | Proteases/Proteasome |
Cathepsin X-IN-1 (compound 25) 降低人前列腺癌细胞 PC-3 的迁移且具有较低的细胞毒性,它是组织蛋白酶 X 的有效抑制剂 (IC50 = 7.13 μM)。 | |||
T77526 |
Pim-1 kinase inhibitor 4
|
Apoptosis; Pim | Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling |
Pim-1 kinase inhibitor 4 是一种高效的 Pim-1 激酶 抑制剂,IC50 值为 17.01 nM。Pim-1 kinase inhibitor 4 还具有抗氧化活性和潜在的抗癌活性,对 DPPH 有抑制作用。Pim-1 kinase inhibitor 4 促进 PC-3 细胞凋亡 (apoptosis),对 PC-3 细胞生长有抑制作用,IC50 为 16 nM。Pim-1 kinase inhibitor 4 可用于研究前列腺癌。 | |||
T4306 |
CCG-203971
CCG203971 |
Rho; Ras | Cell Cycle/Checkpoint; GPCR/G Protein; MAPK |
CCG-203971 是一种Rho/MRTF/SRF 通路抑制剂,具有潜在的抗转移作用。它有效靶向 RhoA/C 激活的 SRE 荧光素酶,IC50为 6.4 μM。它抑制 PC-3 细胞迁移,IC50为 4.2 μM。 | |||
T60341 |
Pyruvate Carboxylase-IN-1
|
Others | Others |
Pyruvate Carboxylase-IN-1 (compound 37) 是一种有效的丙酮酸羧化酶(PC) 抑制剂,对于基于细胞裂解物和基于细胞的 PC 活性,IC50s 分别为 0.204 和 0.104 μM。Pyruvate Carboxylase-IN-1 是毛兰素的天然类似物。Pyruvate Carboxylase-IN-1 抑制 PC 的酶活性,介导人肝细胞癌 (HCC) 的抗癌作用。 | |||
T18517 |
PC Azido-PEG11-NHS carbonate ester
|
Others | Others |
PC Azido-PEG11-NHS carbonate ester is a PEG-based PROTAC linker utilized in PROTAC synthesis[1]. | |||
T81479 |
Phytochelatin 3
PC 3 |
||
Phytochelatin 3 (PC 3)是一种具有金属螯合能力的小型肽,主要用途为螯合重金属离子。 | |||
T18525 |
PC SPDP-NHS carbonate ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
PC SPDP-NHS carbonate ester is a cleavable linker compound utilized in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T18519 |
PC-Biotin-PEG4-NHS carbonate
|
Others | Others |
PC-Biotin-PEG4-NHS carbonate is a polyethylene glycol (PEG) derived linker employed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T84377 |
1,2-Dilinoleoyl-sn-glycero-3-PC
Dilinoleoyllecithin |
Others | Others |
1,2-Dilinoleoyl-sn-glycero-3-PC(Dilinoleoyllecithin)为一种磷脂,主要应用于人造膜的制造。 | |||
T18523 |
PC Methyltetrazine-PEG4-NHS carbonate ester
|
Others | Others |
PC Methyltetrazine-PEG4-NHS carbonate ester is a polyethylene glycol (PEG) derived linker specifically designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1]. | |||
T16438 |
PC Biotin-PEG3-azide
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
PC Biotin-PEG3-azide is a cleavable three-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker, employed in the synthesis of ADCs[1]. | |||
T81476 |
Phytochelatin 4 TFA
PC 4 TFA |
||
Phytochelatin 4 (PC 4) TFA,一种在植物中发现的短肽,富含 Cys,且具有 γ-Glu-Cys 基序。 | |||
T18520 |
PC-Biotin-PEG4-PEG3-azide
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
PC-Biotin-PEG4-PEG3-azide is a cleavable 7-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker employed for the synthesis of ADCs [1]. | |||
T83476 |
1,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine
DHPC |
Others | Others |
1,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine (DHPC) 是生物活性磷脂化合物,属于磷脂酰胆碱 (PC) 的衍生物。 | |||
T81477 |
Phytochelatin 4
PC 4 |
||
Phytochelatin 4 (PC 4)为植物体内富含Cys的小分子短肽,其结构特征为含有γ-Glu-Cys基序。 | |||
T37123 |
1,2-Dioctanoyl PC
|
Others | Others |
Phosphatidylcholine (PC) species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Dioctanoyl PC is a synthetic analog of natural phosphatidylcholine species containing saturated C8:O fatty acids in the sn-1 and sn-2 positions of the glycerol backbone. It exhibits a critical micelle concentration (CMC) value of 0.25 mM at 27°C. 1,2-Dioctanoyl PC serves as an efficient substrate for phospholipase D (PLD) as well as sPLA2 isozymes from bovine pancreas and bee venom... | |||
T18518 |
PC Biotin-PEG3-NHS ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
PC Biotin-PEG3-NHS ester is a cleavable ADC linker comprising three PEG units. This linker is specifically designed for use in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T35580 |
POV-PC
|
Others | Others |
Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. 1-(Palmitoyl)-2-(5-oxovaleroyl)-phosphatidylcholine, or POV-PC, is one of the oxLDL species derived from 2-arachidonoyl or eicosapentanoyl phospholipids. POV-PC conf... | |||
T18516 |
PC Alkyne-PEG4-NHS ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
PC Alkyne-PEG4-NHS ester is a cleavable 4-unit PEG linker employed for the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T17586 |
Biotin-PEG4-PC-PEG4-alkyne
|
Others | Others |
Biotin-PEG4-PC-PEG4-alkyne is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker utilized in the synthesis of PROTACs[1]. | |||
T81478 |
Phytochelatin 3 TFA
PC 3 TFA |
||
Phytochelatin 3 (PC 3) TFA,一小分子螯合肽,专用于重金属离子螯合。 | |||
T84981 |
1,2-Dipropionyl-sn-glycero-3-PC
1,2-Dipropionyl-sn-glycero-3-Phosphatidylcholine |
Others | Others |
1,2-Dipropionyl-sn-glycero-3-phosphocholine (PC) is a phospholipid characterized by the presence of propionic acid at its sn-1 and sn-2 positions. This compound has applications in the investigation of interactions between water and the phosphocholine headgroup in aqueous solutions. | |||
T78306 |
Ulenistamab
PBP1510 |
||
Ulenistamab (PBP1510)为首创人源化IgG1单克隆抗体,专一靶向胰腺癌上调因子(PAUF),适用于胰腺癌(PC)的研究。 | |||
T75000 | Mal-Pc | Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Mal-Pc为基于酞菁和马来酰亚胺设计的多功能分子光敏剂。它能在癌细胞内与GSH反应,耗减GSH并抑制其聚集,进而增强ROS介导的PDT效果。 | |||
T37623 |
1,2-Dierucoyl-sn-glycero-3-PC
|
Others | Others |
1,2-Dierucoyl-sn-glycero-3-PC is a phospholipid containing erucic acid at the sn-1 and sn-2 positions. It has been used in the study of lipid membranes and to determine the effect of long-chain phospholipids on the secondary structure of human islet amyloid polypeptide (hIAPP). | |||
T36172 |
KOdiA-PC
|
Others | Others |
Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl) phosphatidylcholine, or KOdiA-PC, is one of the most potent CD36 ligands among the oxLDL species. KOdiA-PC confers CD36 scave... | |||
T79495 |
VEGFR-2-IN-32
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
VEGFR-2-IN-32(Comp 3a)作为一种VEGFR-2的抑制剂,其IC50值为8.93 nM。该化合物对PC-3细胞表现出细胞毒性,IC50为1.22 μM,适用于前列腺癌研究。 | |||
T60727 |
B-Raf IN 8
|
Others | Others |
B-Raf IN 8 (compound 7g) 是 B-Raf 的有效抑制剂 (IC50 = 70.65 nM)。B-Raf IN 8 显示出抗肿瘤活性,其对肝细胞癌 (HEPG-2)、结肠癌 (HCT-116),乳腺癌 (MCF-7) 和人前列腺癌 (PC-3) 细胞的 IC50值分别为9.78、13.78、18.52 和 29.85 μM。 | |||
T18521 |
PC DBCO-PEG3-biotin
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
PC DBCO-PEG3-biotin is a trimeric polyethylene glycol (PEG) linker, specifically designed for antibody-drug conjugate (ADC) synthesis, with a cleavable moiety consisting of a dibenzocyclooctyne (DBCO) group and a biotin molecule. This linker provides a platform for the efficient attachment of drugs to antibodies, facilitating the targeted delivery and controlled release of therapeutic agents in ADCs[1]. | |||
T85301 |
ABO hydrochloride
|
Others | Others |
ABO acts as an annexin A7 modulator, specifically binding to Thr286 to inhibit its phosphorylation on threonine (not on serine or tyrosine) residues within human umbilical vein endothelial cells (HUVECs). This compound furthers the annexin A7 interaction with the EF-hand protein GCA, leading to reduced GCA phosphorylation, lowered intracellular calcium levels, and enhanced autophagy in COS-7 cells. Moreover, ABO lessens phosphorylation of the microtubule-associated protein 1 light chain (LC3) in... | |||
T79558 |
fac-[Re(CO)3(L3)(H2O)][NO3]
|
Others | Others |
fac-[Re(CO)3(L3)(H2O)][NO3](简称compound 3),是一种与线粒体功能障碍相关的抗前列腺癌剂。这种铼(I)三羰基水配合物对前列腺癌细胞系(PC-3)表现出显著的细胞毒性,其IC50值为0.32 μM。研究表明,fac-[Re(CO)3(L3)(H2O)][NO3]主要在线粒体中积聚,能够降低PC-3细胞的ATP生成,进而触发细胞副凋亡(paraptosis)机制,而不通过引发坏死、凋亡或自噬途径作用。 | |||
T79152 |
PROTAC EGFR degrader 8
|
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
PROTACEGFRdegrader 8 (T-184) 是一种能够定向降解EGFR的PROTACEGFR降解剂,其在HCC827细胞中的DC50为15.56 nM。该化合物有效抑制多种肺癌细胞系,包括H1975、PC-9和HCC827,其IC50分别为7.72 nM、121.9 nM和14.21 nM。PROTACEGFRdegrader 8 主要用于研究非小细胞肺癌(NSCLC)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19085 |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
POPC,2-油酰-1-棕榈锡甘油-3-磷酸胆碱,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine |
Others | Others |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) 是生物膜的主要成分,是一种磷脂。它用于脂质体的制备以及脂质双层的特性的研究。 | |||
T74236 |
1-Oleoyl-2-palmitoyl-sn-glycero-3-PC
|
Others | Others |
1-Oleoyl-2-palmitoyl-sn-glycero-3-PC,由油酸衍生,用于脂质体合成。 | |||
T4S2126 |
Ginkgetin
银杏双黄酮,银杏素 |
Apoptosis; Wnt/beta-catenin; COX; STAT; Autophagy | Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; Stem Cells |
Ginkgetin 是从银杏叶中分离得到的一种双黄酮,具有抗肿瘤、抗炎、神经保护、抗真菌的作用。它也是 Wnt 信号抑制剂,IC50值为 5.92 μM。 | |||
T81529 |
Peganumine A
|
Others | Others |
Peganumine A,一种天然产物,源自Peganum harmala,具备对HL-60、MCF-7、PC-3、HepG2细胞线显示出细胞毒性作用,其IC50值依次为5.8、38.5、40.2、55.4 µM[1]< /sup>。 | |||
T83471 |
10-Deacetyl-13-oxobaccatin III
|
||
10-Deacetyl-13-oxobaccatin III是一款从Taxus sumatrana分离的紫杉烷。在30 μg/mL的浓度下,对A498、NCI-H226、A549、PC-3细胞系展现细胞毒性作用,其抑制率分别达到29.7%、49.2%、43.9%、65.3%。 | |||
T36791 |
Lysophosphatidylcholine 18:2
|
Others | Others |
1-Linoleoyl-2-hydroxy-sn-glycero-3-PC (LGPC) is a lysophospholipid containing linoleic acid at thesn-1 position that has been found in mouse heart, lung, liver, spleen, kidney, plasma, and serum.1Serum levels of LGPC decrease with increasing insulin resistance and dysglycemia in humans.2 1.Okudaira, M., Inoue, A., Shuto, A., et al.Separation and quantification of 2-acyl-1-lysophospholipids and 1-acyl-2-lysophospholipids in biological samples by LC-MS/MSJ. Lipid Res.55(10)2178-2192(2014) 2.Gall, ... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04966 |
PCSK9 Protein, Human, Recombinant (D374Y, His)
LDLCQ1,NARC-1,PC9,NARC1,... |
Human | HEK293 Cells |
PCSK9 Protein, Human, Recombinant (D374Y, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.5 kDa and the accession number is Q8NBP7-1. | |||
TMPY-00408 |
PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His)
FH3,proprotein convertase subtilisin/kexin type 9,LDLCQ1... |
Human | HEK293 Cells |
PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.6 kDa and the accession number is AAV67948.1. | |||
TMPY-05131 |
PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated
NARC-1,PC9,LDLCQ1,NARC1,... |
Human | HEK293 Cells |
PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 74.3 kDa and the accession number is Q8NBP7-1. | |||
TMPY-01635 |
PCSK1 Protein, Human, Recombinant (His)
proprotein convertase subtilisin/kexin type 1,S... |
Human | HEK293 Cells |
Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the proteolytic cleavage of prohormones to their intermediate (or sometimes completely cleaved) forms. It is present only in neuroendocrine cells such as brain, pituitary and adrenal, and most often cleaves after a pair of basic residues within prohormones but can occasionally cleav... | |||
TMPJ-01088 |
PCDH1 Protein, Human, Recombinant (His)
PC42,PCDH1,Protocadherin-1 |
Human | HEK293 Cells |
Protocadherin-1, also known as Cadherin-like protein 1, Protocadherin-42 and PCDH1, belongs to the protocadherin subfamily within the cadherin superfamily. PCDH1 contains seven cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. PCDH1 can be detected as early as embryonic day 9.5. In early embryogenesis, expression is especially prominent in blood vessels. The tight spatial and temporal regulation of Pcdh1 expression suggests that this protocadherin plays multiple ... | |||
TMPY-05218 |
PCSK9 Protein, Human, Recombinant (mFc)
HCHOLA3,PC9,proprotein convertase subtilisin/kexin ... |
Human | HEK293 Cells |
PCSK9 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 97.4 kDa and the accession number is Q8NBP7-1. | |||
TMPY-05199 |
PCSK9 Protein, Human, Recombinant (D374Y, mFc)
PC9,proprotein convertase subtilisin/kexin type 9,F... |
Human | HEK293 Cells |
PCSK9 Protein, Human, Recombinant (D374Y, mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 97.5 kDa and the accession number is Q8NBP7-1. | |||
TMPY-03880 |
Protein C Protein, Human, Recombinant (His)
PROC,APC,THPH4,protein C, inactivator of coagulatio... |
Human | HEK293 Cells |
Protein C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P04070. | |||
TMPK-00852 |
ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated
E-NPP 1,NPPase,PC1,NPP1,... |
Human | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 98.29 kDa and the accession number is P22413. | |||
TMPY-03395 |
PC4/SUB1 Protein, Human, Recombinant (His)
PC4,RPO2TC1,SUB1 homolog, transcr... |
Human | E. coli |
SUB1 belongs to the transcriptional coactivator PC4 family. It is a general coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. SUB1 binds single-stranded DNA. Single-stranded DNA-binding proteins play many roles in nucleic acid metabolism, but their importance during transcription remains unclear. SUB1 exhibits strong genetic interactions with factors necessary for promoter melting. It loc... | |||
TMPY-05114 |
PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His), Biotinylated
LDLCQ1,NARC-1,PC9,FH3,NARC1 |
Human | HEK293 Cells |
PCSK9 Protein, Human, Recombinant (D374Y & V474I & G670E, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.6 kDa and the accession number is Q8NBP7-1. | |||
TMPK-00781 |
ENPP1 Protein, Mouse, Recombinant (His)
ENPP1,PC1,PCA1A... |
Mouse | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 95.99 kDa and the accession number is P06802-1. | |||
TMPK-00853 |
ENPP1 Protein, Human, Recombinant (N-His)
PDNP1,NPP1,NPPase,PCA1AR... |
Human | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (N-His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 96.5 kDa and the accession number is P22413. | |||
TMPK-00854 |
ENPP1 Protein, Human, Recombinant (C-His)
M6S1,E-NPP 1,PCA1,PDNP |
Human | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 96.5 kDa and the accession number is P22413. | |||
TMPY-05270 |
PCSK9 Protein, Human, Recombinant (D374Y, mFc), Biotinylated
FH3,NARC-1,PC9,LDLCQ1,proprotein ... |
Human | HEK293 Cells |
PCSK9 Protein, Human, Recombinant (D374Y, mFc), Biotinylated is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 97.5 kDa and the accession number is Q8NBP7-1. | |||
TMPJ-00369 |
PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated
Subtilisin/Kexin-Like Protease PC9,PCSK9,N... |
Human | HEK293 Cells |
PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-8xHis-HA-Avi tag. The predicted molecular weight is 18 and 58-70 and 90-150 KDa and the accession number is Q8NBP7. | |||
TMPJ-00368 |
PCSK9 Protein, Human, Recombinant (Avi), Biotinylated
Subtilisin/Kexin-Like Protease PC9,PC9,NAR... |
Human | HEK293 Cells |
PCSK9 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 19&65 KDa and the accession number is Q8NBP7. | |||
TMPY-04722 |
DcR1/TRAILR3 Protein, Human, Recombinant (His)
TRAILR3,TRID,DCR1,TRAIL-R3,CD263,DCR1-TNFR... |
Human | HEK293 Cells |
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC. | |||
TMPK-00357 |
CD229 Protein, Human, Recombinant (His & Avi)
LY9,T100,AI893573,SLAMF3,Lgp100,CD229 |
Human | HEK293 Cells |
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. CD229 Protein, Human, Recombinant (His & Avi) is... | |||
TMPK-00358 |
CD229 Protein, Human, Recombinant (His & Avi), Biotinylated
T100,Lgp100,LY9,AI893573,CD229,SLAMF3 |
Human | HEK293 Cells |
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. CD229 Protein, Human, Recombinant (His & Avi), B... | |||
TMPY-04451 |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
AMPK, AMPK(α1, β1, γ1) |
Human | Baculovirus Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1. | |||
TMPY-03878 |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone... |
Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-02501 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant
CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-02030 |
CD82 Protein, Human, Recombinant (His)
CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T... |
Human | HEK293 Cells |
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud... | |||
TMPY-01894 |
SIGIRR Protein, Human, Recombinant (His)
TIR8,single immunoglobulin and toll-interleukin 1 r... |
Human | HEK293 Cells |
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1. | |||
TMPY-01247 |
FLT3 Protein, Human, Recombinant (T227M, His)
FLK2,FLK-2,CD135,STK1,fms-related tyrosine... |
Human | HEK293 Cells |
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1. | |||
TMPY-02779 |
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
thyroid peroxidase,MSA,TPX,TDH2A |
Human | Baculovirus Insect Cells |
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i... | |||
TMPY-03290 |
HGF Protein, Mouse, Recombinant
hepatocyte growth factor (hepapoietin A,NK1,scatter... |
Mouse | HEK293 Cells |
HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1. | |||
TMPY-04970 |
TIGIT Protein, Human, Recombinant (hFc)
WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom... |
Human | HEK293 Cells |
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1. | |||
TMPY-01147 |
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
RSPO,CRISTIN3,R-spondin 1 |
Human | HEK293 Cells |
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1. | |||
TMPY-04346 |
PD-L2 Protein, Human, Recombinant (His)
PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed... |
Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1. | |||
TMPY-00947 |
VCAM-1 Protein, Human, Recombinant (hFc)
INCAM-100,CD106,VCAM-1,vascular c... |
Human | HEK293 Cells |
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1. | |||
TMPY-01949 |
CD19 Protein, Human, Recombinant (His)
CD19 molecule,B4,CVID3 |
Human | HEK293 Cells |
CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1. | |||
TMPY-04165 |
FGFR3 Protein, Human, Recombinant (His)
JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33... |
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1. | |||
TMPY-00820 |
IgG1 Fc Protein, Human, Recombinant (C103S)
Ighg1,IgG1 Fc |
Human | HEK293 Cells |
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1. | |||
TMPY-01146 |
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
HHF5,CD220,insulin receptor |
Human | HEK293 Cells |
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1. | |||
TMPY-04348 |
CTLA-4 Protein, Human, Recombinant (His)
ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ... |
Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1. | |||
TMPY-02813 |
ErbB4 Protein, Human, Rhesus, Recombinant (His)
erb-b2 receptor tyrosine kinase 4 |
Human,Rhesus | HEK293 Cells |
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1. | |||
TMPY-05220 |
TSLP Protein, Human, Recombinant (R127A & R130S, His)
thymic stromal lymphopoietin |
Human | HEK293 Cells |
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1. | |||
TMPY-01827 |
CD30/TNFRSF8 Protein, Human, Recombinant (His)
D1S166E,tumor necrosis factor receptor sup... |
Human | HEK293 Cells |
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1. | |||
TMPY-00853 |
IL-1RA Protein, Human, Recombinant
DIRA,IL1RA,interleukin 1 receptor antagoni... |
Human | E. coli |
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1. | |||
TMPY-01850 |
CEACAM3 Protein, Human, Recombinant (His)
W282,W264,CEA,CD66D,CGM1,MGC11987... |
Human | HEK293 Cells |
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp... | |||
TMPY-02245 |
SNAP-25 Protein, Human, Recombinant (His)
synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ |
Human | E. coli |
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp... | |||
TMPY-00203 |
LOXL2 Protein, Mouse, Recombinant (His)
1110004B06Rik,4930526G1<... |
Mouse | HEK293 Cells |
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act... | |||
TMPY-01281 |
ACVR2B Protein, Mouse, Recombinant (His)
ActRIIB,activin A receptor, type IIB,4930516B21... |
Mouse | HEK293 Cells |
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1. | |||
TMPY-01851 |
CD73 Protein, Human, Recombinant (His)
eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD... |
Human | HEK293 Cells |
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1. | |||
TMPY-02525 |
RGMA Protein, Human, Recombinant (His)
repulsive guidance molecule family member a,RGM |
Human | HEK293 Cells |
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form... | |||
TMPY-03967 |
BTN3A3 Protein, Human, Recombinant (His)
BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3 |
Human | HEK293 Cells |
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1. | |||
TMPY-05208 |
PD-L1 Protein, Human, Recombinant
CD274 molecule,PDCD1L1,PD-L1,PDL<... |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-00978 |
Progranulin Protein, Human, Recombinant (His)
PGRN,PCDGF,CLN11,Granulin,GP88,GE... |
Human | HEK293 Cells |
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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T38356 |
1,2-Dipalmitoyl-13C-sn-glycero-3-PC
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1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation... |