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Cat. No. Product Name Target Signaling Pathways
T81546 PARG-IN-4

Others Others
PARG-IN-4(公式 (A))是一款具备口服活性与细胞渗透能力的PARG抑制剂,能在小鼠模型中有效地抑止肿瘤生长,适用于癌症研究。
T83799 6-alkyne NAD+ sodium

β-Nicotinamide-N6-propargyladenine dinucleotide,6-Parg NAD,6-alkyne Nicotinamide adenine dinucleotide,Click Tag™ 6-alkyne NAD

6-炔基NAD+是一种可点击的信号分子及酶辅因子NAD+形式。它与荧光标签联用,用于检测聚(ADP-核糖)聚合酶(PARP)蛋白质底物。
T1440 Ethacridine lactate monohydrate

乳酸依沙吖啶一水物,利凡诺

Antibacterial; Antibiotic Microbiology/Virology
Ethacridine lactate monohydrate 是一种聚 (ADP-核糖) 糖基水解酶 (PARG) 抑制剂,有抗金黄色葡萄球菌和其他革兰氏阳性球菌的活性。它也是抗菌剂和流产剂。
T5967 Ethacridine lactate

乳酸依沙吖啶,Acrinol,6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE

Others; Antibacterial Microbiology/Virology; Others
Ethacridine lactate (Acrinol) 是一种聚 (ADP-核糖) 糖水解酶 (PARG) 抑制剂,也是一种抗菌剂和流产剂。它有抗金黄色葡萄球菌和其他革兰氏阳性球菌的活性。
T12284 O-Propargyl-Puromycin

OP-puro,O-Propargylpuromycin

Others Others
O-Propargyl-Puromycin (OP-puro) 是一种高效的蛋白质合成抑制剂,是一种嘌呤霉素炔类似物。
T38173 Propargylcholine

Propargylcholine (bromide)

Antibacterial Microbiology/Virology
Propargylcholine (Propargylcholine (bromide)) 是一种炔烃修饰的胆碱类似物,在铜绿假单胞菌中 Dgc 酶催化的二甲基甘氨酸去甲基化水平上抑制胆碱分解代谢。
T1578 Pargyline hydrochloride

优降宁盐酸盐,Pargylamine hydrochloride

MAO; Monoamine Oxidase Metabolism; Neuroscience
Pargyline hydrochloride (Pargylamine hydrochloride) 是不可逆的单胺氧化酶抑制剂,可作用于 MAO-A (Ki=13 μM) 和 MAO-B (Ki=0.5 μM) ,具有降压和抗癌作用。
T18566 Propargyl-PEG12-bromide

Others; PROTAC Linker Others; PROTAC
Propargyl-PEG12-bromide 是 PEG 类PROTAC linker,可用于合成 PROTAC 分子。
T18831 Thalidomide-propargyl

Others; Ligand for E3 Ligase Others; PROTAC
Thalidomide-propargyl 是一种基于 Thalidomide 的 Cereblon 配体,可用于募集 CRBN 蛋白。它能够利用 linker 与靶蛋白配体连接,得到含 IMiD 的 PROTAC。
T38079 DL-Propargylglycine HCl

DL-Propargyl Glycine HCl,DL-Propargyl Glycine hydrochloride

Others Others
DL-Propargylglycine HCl (DL-Propargyl Glycine HCl)是一种有效的胱硫氨酸 γ-裂解酶的不可逆抑制剂,可用于研究心力衰竭。
T39849 Propargite

Parasite Microbiology/Virology
Propropgite 通过诱导 DNA 损伤来诱导 β 细胞坏死。它诱导 MIN6 细胞死亡的 IC50为 1 μM.。它可用于杀死螨虫。
T20129 L-Propargylglycine

(S)-Propargylglycine,(S)-alpha.Propargylglycine,Propargylglycine,L-炔丙基甘氨酸

Others Others
L-Propargylglycine ((S)-Propargylglycine) 是一种脯氨酸酶抑制剂。
T9389 Thalidomide-PEG4-Propargyl

Thalidomide-O-PEG4-Propargyl

E3 Ligase Ligand-Linker Conjugate PROTAC
Thalidomide-PEG4-Propargyl (Thalidomide-O-PEG4-Propargyl) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物,。
T16605 Propargyl-PEG3-acid

丙炔基-二聚乙二醇-羧酸

PROTAC Linker; ADC Linker Antibody-drug Conjugate/ADC Related; PROTAC
Propargyl-PEG3-acid 是一种不可切割的,含 3 个单元 PEG 的 ADC 接头,也是一种基于 PEG 的 PROTAC 接头,可用于合成 6-OHDA-PEG3-yne。 6-OHDA-PEG3-yne 包含 6-OHDA 和炔丙基-PEG3-酸。
T18574 Propargyl-PEG17-methane

MPEG16-Propyne

Others; PROTAC Linker Others; PROTAC
Propargyl-PEG17-methane (MPEG16-Propyne) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
T0300 Pargyline

Pargylamine,Paragyline,优降宁

MAO; Monoamine Oxidase Metabolism; Neuroscience
Pargyline (Pargylamine) 是不可逆的单胺氧化酶抑制剂,对MAO-A 和MAO-B 的Ki 分别为 13 μM 和 0.5 μM,具有降压和抗癌作用。
T15694 L-Homopropargylglycine

Others Others
L-Homopropargylglycine 是一种蛋氨酸类似物,常用于生物正交非经典氨基酸标记中来检测细菌活性和检测蛋白合成。
T18568 Propargyl-PEG11-methane

Others; PROTAC Linker Others; PROTAC
Propargyl-PEG11-methane 是 PEG 类 PROTAC linker。可用于合成 PROTAC 分子。
T16326 Cipargamin

KAE609,NITD609

Parasite Microbiology/Virology
Cipargamin (NITD609) 是一种有效的抗疟药物,对恶性疟原虫的IC50值约为 1 nM。
T18588 Propargyl-PEG5-Ms

Propargyl-PEG6-Ms

Others; PROTAC Linker Others; PROTAC
Propargyl-PEG5-Ms (Propargyl-PEG6-Ms) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
T18560 Propargyl-C1-NHS ester

4-戊炔酸琥珀亚胺酯,4-Pentynoic Acid Succinimidyl Ester

Others; ADC Linker Antibody-drug Conjugate/ADC Related; Others
Propargyl-C1-NHS ester (4-Pentynoic Acid Succinimidyl Ester) 是一种不可切割的 ADC 接头,可用于合成抗体偶联药物。
T18823 Thalidomide-O-amido-PEG4-propargyl

Others Others
Thalidomide-O-amido-PEG4-propargyl is a polyethylene glycol (PEG)-based linker employed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T14020 (2-Pyridyldithio)-PEG4-propargyl

Others Others
(2-Pyridyldithio)-PEG4-propargyl is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].
T15884 m-PEG4-propargyl

Others Others
m-PEG4-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18591 Propargyl-PEG8-SH

Others Others
Propargyl-PEG8-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T14758 Boc-NH-PEG8-propargyl

Others Others
Boc-NH-PEG8-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16300 NH-bis(PEG2-propargyl)

Others Others
NH-bis(PEG2-propargyl) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T14740 Boc-aminooxy-PEG2-propargyl

Boc-NH-PEG2-propargyl

Others Others
Boc-NH-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
T16249 N-(Propargyl-PEG4)-N-bis(PEG4-acid)

Others Others
N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker extensively utilized in the synthesis of PROTACs (proteolysis targeting chimeras)[1].
T16612 Propargyl-PEG3-phosphonic acid

Others Others
Propargyl-PEG3-phosphonic acid, a PEG-based PROTAC linker, is utilized for PROTAC synthesis[1].
T16610 Propargyl-PEG3-OCH2-Boc

Others Others
Propargyl-PEG3-OCH2-Boc is a polyethylene glycol (PEG)-derived linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
T16631 Propargyl-PEG4-sulfonic acid

Others Others
Propargyl-PEG4-sulfonic acid is a PEG4-based linker compound utilized in PROTAC synthesis[1].
T16246 N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester

Others Others
N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a polyethylene glycol (PEG)-based linker employed for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].
T17633 Bis-propargyl-PEG11

Others Others
Bis-propargyl-PEG11 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T14660 Bis-propargyl-PEG7

Others Others
Bis-propargyl-PEG7 is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs). It is particularly employed for the synthesis of polymer-linked multimers of guanosine-3',5'-cyclic monophosphates[1].
T16603 Propargyl-PEG2-OH

Others Others
Propargyl-PEG2-OH is a polyethylene glycol (PEG)-based PROTAC linker, specifically designed for efficient synthesis of Thalidomide-O-PEG2-propargyl.
T16604 Propargyl-PEG2-Tos

Others Others
Propargyl-PEG2-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16248 N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester)

n-propargyl-peg4-carbonyl-n-bis-peg1-methyl-ester

Others Others
N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a polyethylene glycol (PEG) based linker, employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
T18589 Propargyl-PEG6-SH

Others Others
Propargyl-PEG6-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18189 m-PEG3-Sulfone-PEG4-propargyl

Others Others
m-PEG3-Sulfone-PEG4-propargyl is a polyethylene glycol (PEG)-based prodrug-induced degradation (PROTAC) linker. It is utilized in the efficient synthesis of PROTACs, a class of heterobifunctional molecules designed to selectively target and degrade specific protein targets[1].
T18452 N-methyl-N'-(propargyl-PEG4)-Cy5

Others Others
N-methyl-N'-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker suitable for PROTAC synthesis[1].
T18176 m-PEG25-Propargyl

Others Others
m-PEG25-Propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17634 Bis-propargyl-PEG13

Others Others
Bis-propargyl-PEG13 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18567 Propargyl-PEG12-methane

Others Others
Propargyl-PEG12-methane is a polyethylene glycol (PEG)-based linker utilized in PROTAC synthesis, specifically for PEG-based proteolysis-targeting chimeras (PROTACs)[1].
T18070 Lenalidomide-propargyl-C2-NH2 hydrochloride

Others Others
Lenalidomide-propargyl-C2-NH2 hydrochloride is a compound that features a cereblon (CRBN) ligand for the E3 ubiquitin ligase, as well as a linker. It is utilized in the development of the PROTAC MD-224[1] system.
T39398 Propargyl-PEG6-Br

Propargyl-PEG6-Br

Others Others
Propargyl-PEG6-Br is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T69217 Pargolol

Others Others
Pargolol is a beta adrenergic receptor antagonist.
T38580 Azido-PEG4-propargyl

Azido-PEG4-propargyl

Others Others
Azido-PEG4-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T24666 Propargyl-PEG14-alcohol

Others Others
Propargyl-PEG14-alcohol is a PEG derivative containing a hydroxyl group and a propargyl group. PEG Linkers are useful in the development of antibody drug conjugates. The hydroxyl group enables further derivatization or replacement with other reactive func
T38689 Propargyl-PEG5-Br

Propargyl-PEG5-Br

Others Others
Propargyl-PEG5-Br is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

化合物

PARG-IN-4
Cat.No: T81546
Synonym:
Target: Others
6-alkyne NAD+ sodium
Cat.No: T83799
Synonym: β-Nicotinamide-N6-propargyladenine dinucleotide,6-Parg NAD,6-alkyne Nicotinamide adenine dinucleotide,Click Tag™ 6-alkyne NAD
Target:
Ethacridine lactate monohydrate
Cat.No: T1440
Synonym: 乳酸依沙吖啶一水物,利凡诺
Target: Antibacterial, Antibiotic
Ethacridine lactate
Cat.No: T5967
Synonym: 乳酸依沙吖啶,Acrinol,6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE
Target: Others, Antibacterial
O-Propargyl-Puromycin
Cat.No: T12284
Synonym: OP-puro,O-Propargylpuromycin
Target: Others
Propargylcholine
Cat.No: T38173
Synonym: Propargylcholine (bromide)
Target: Antibacterial
Pargyline hydrochloride
Cat.No: T1578
Synonym: 优降宁盐酸盐,Pargylamine hydrochloride
Target: MAO, Monoamine Oxidase
Propargyl-PEG12-bromide
Cat.No: T18566
Synonym:
Target: Others, PROTAC Linker
Thalidomide-propargyl
Cat.No: T18831
Synonym:
Target: Others, Ligand for E3 Ligase
DL-Propargylglycine HCl
Cat.No: T38079
Synonym: DL-Propargyl Glycine HCl,DL-Propargyl Glycine hydrochloride
Target: Others
Propargite
Cat.No: T39849
Synonym:
Target: Parasite
L-Propargylglycine
Cat.No: T20129
Synonym: (S)-Propargylglycine,(S)-alpha.Propargylglycine,Propargylglycine,L-炔丙基甘氨酸
Target: Others
Thalidomide-PEG4-Propargyl
Cat.No: T9389
Synonym: Thalidomide-O-PEG4-Propargyl
Target: E3 Ligase Ligand-Linker Conjugate
Propargyl-PEG3-acid
Cat.No: T16605
Synonym: 丙炔基-二聚乙二醇-羧酸
Target: PROTAC Linker, ADC Linker
Propargyl-PEG17-methane
Cat.No: T18574
Synonym: MPEG16-Propyne
Target: Others, PROTAC Linker
Pargyline
Cat.No: T0300
Synonym: Pargylamine,Paragyline,优降宁
Target: MAO, Monoamine Oxidase
L-Homopropargylglycine
Cat.No: T15694
Synonym:
Target: Others
Propargyl-PEG11-methane
Cat.No: T18568
Synonym:
Target: Others, PROTAC Linker
Cipargamin
Cat.No: T16326
Synonym: KAE609,NITD609
Target: Parasite
Propargyl-PEG5-Ms
Cat.No: T18588
Synonym: Propargyl-PEG6-Ms
Target: Others, PROTAC Linker
Propargyl-C1-NHS ester
Cat.No: T18560
Synonym: 4-戊炔酸琥珀亚胺酯,4-Pentynoic Acid Succinimidyl Ester
Target: Others, ADC Linker
Thalidomide-O-amido-PEG4-propargyl
Cat.No: T18823
Synonym:
Target: Others
(2-Pyridyldithio)-PEG4-propargyl
Cat.No: T14020
Synonym:
Target: Others
m-PEG4-propargyl
Cat.No: T15884
Synonym:
Target: Others
Propargyl-PEG8-SH
Cat.No: T18591
Synonym:
Target: Others
Boc-NH-PEG8-propargyl
Cat.No: T14758
Synonym:
Target: Others
NH-bis(PEG2-propargyl)
Cat.No: T16300
Synonym:
Target: Others
Boc-aminooxy-PEG2-propargyl
Cat.No: T14740
Synonym: Boc-NH-PEG2-propargyl
Target: Others
N-(Propargyl-PEG4)-N-bis(PEG4-acid)
Cat.No: T16249
Synonym:
Target: Others
Propargyl-PEG3-phosphonic acid
Cat.No: T16612
Synonym:
Target: Others
Propargyl-PEG3-OCH2-Boc
Cat.No: T16610
Synonym:
Target: Others
Propargyl-PEG4-sulfonic acid
Cat.No: T16631
Synonym:
Target: Others
N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester
Cat.No: T16246
Synonym:
Target: Others
Bis-propargyl-PEG11
Cat.No: T17633
Synonym:
Target: Others
Bis-propargyl-PEG7
Cat.No: T14660
Synonym:
Target: Others
Propargyl-PEG2-OH
Cat.No: T16603
Synonym:
Target: Others
Propargyl-PEG2-Tos
Cat.No: T16604
Synonym:
Target: Others
N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester)
Cat.No: T16248
Synonym: n-propargyl-peg4-carbonyl-n-bis-peg1-methyl-ester
Target: Others
Propargyl-PEG6-SH
Cat.No: T18589
Synonym:
Target: Others
m-PEG3-Sulfone-PEG4-propargyl
Cat.No: T18189
Synonym:
Target: Others
N-methyl-N'-(propargyl-PEG4)-Cy5
Cat.No: T18452
Synonym:
Target: Others
m-PEG25-Propargyl
Cat.No: T18176
Synonym:
Target: Others
Bis-propargyl-PEG13
Cat.No: T17634
Synonym:
Target: Others
Propargyl-PEG12-methane
Cat.No: T18567
Synonym:
Target: Others
Lenalidomide-propargyl-C2-NH2 hydrochloride
Cat.No: T18070
Synonym:
Target: Others
Propargyl-PEG6-Br
Cat.No: T39398
Synonym: Propargyl-PEG6-Br
Target: Others
Pargolol
Cat.No: T69217
Synonym:
Target: Others
Azido-PEG4-propargyl
Cat.No: T38580
Synonym: Azido-PEG4-propargyl
Target: Others
Propargyl-PEG14-alcohol
Cat.No: T24666
Synonym:
Target: Others
Propargyl-PEG5-Br
Cat.No: T38689
Synonym: Propargyl-PEG5-Br
Target: Others
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