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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37801 |
rac-Desethyl Oxybutynin (hydrochloride)
|
Others | Others |
rac-Desethyl oxybutynin is an active metabolite of the muscarinic acetylcholine receptor (mAChR) antagonist oxybutynin .1,2,3rac-Desethyl oxybutynin is formed from oxybutynin by the cytochrome P450 (CYP) isoform CYP3A4.2It binds to mAChRs in isolated rat bladder, submaxillary gland, heart, and colon with Kivalues of 5.38, 3.12, 16, and 5.59 nM, respectively.rac-Desethyl oxybutynin (0.4 and 0.8 mg/kg) reduces micturition pressure in rats.3 | |||
T1049 |
Oxybutynin chloride
Oxybutynin hydrochloride,盐酸奥昔布宁,Oxybutynin HCl |
Potassium Channel; AChR | Membrane transporter/Ion channel; Neuroscience |
Oxybutynin chloride (Oxybutynin HCl) 是一种抗胆碱能药物,用于缓解泌尿和膀胱困难。它抑制血管 Kv 通道,IC50为 11.51 μM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12144 |
N-Desethyl Oxybutynin-d5 hydrochloride
N-Desethyl Oxybutynin D5 hydrochloride |
Others | Others |
N-Desethyl Oxybutynin D5 hydrochloride is the the active metabolite Oxybutynin, is deuterium labeled N-Desethyl Oxybutynin hydrochloride. |