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抑制剂 & 化合物

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天然产物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T35604 Osteocalcin (1-49) (human) (trifluoroacetate salt)

Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget's disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in w...

化合物

Osteocalcin (1-49) (human) (trifluoroacetate salt)
Cat.No: T35604
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T19603 Vitamin K

Kephton,维生素K,Vitamin K1(20)

Endogenous Metabolite Metabolism
Vitamin K (Kephton) 具有凝血作用,对凝血因子、基质-Gla 蛋白和骨钙素很重要。
TN7362 Hederagenin 3-O-(2-O-acetyl-alpha-L-arabinopyranoside)

Others Others
Hederagenin 3-O-(2-O-acetyl-α-L-arabinopyranoside) significantly elevated alkaline phosphatase (ALP) activity and enhanced the protein expression levels of bone sialoprotein (BSP) and osteocalcin (OC).

天然产物

Vitamin K
Cat.No: T19603
Synonym: Kephton,维生素K,Vitamin K1(20)
Target: Endogenous Metabolite
Hederagenin 3-O-(2-O-acetyl-alpha-L-arabinopyranoside)
Cat.No: TN7362
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-03346 Osteocalcin Protein, Rat, Recombinant (GST)

Bone Gla protein,Osteocalcin,Bglap,Gamma-carboxyglu...

Rat E. coli
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Osteocalcin Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 32.6 kDa and the accession number is P04640.
TMPH-02818 Osteocalcin Protein, Mouse, Recombinant (His & SUMO)

Bone Gla protein,Gamma-carboxyglutamic acid-containing prote...

Mouse E. coli
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
TMPH-00380 Osteocalcin Protein, Chicken, Recombinant (His & KSI)

Bone Gla protein,BGLAP,Osteocalcin,Gamma-carboxyglu...

Chicken E. coli
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Osteocalcin Protein, Chicken, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 20.7 kDa and the accession number is P02822.
TMPH-00496 Osteocalcin Protein, Canine, Recombinant (His & KSI)

BGLAP,Gamma-carboxyglutamic acid-containing protein,Oste...

Canine E. coli
Osteocalcin Protein, Canine, Recombinant (His & KSI) is expressed in E. coli.
TMPH-02569 WISP2/CCN5 Protein, Mouse, Recombinant (His)

Ccn5,Connective tissue growth factor-like protein,CCN family...

Mouse P. pastoris (Yeast)
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
TMPY-02287 Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His)

KARP1,XRCC5 & XRCC6,KUB2,KU80,KARP-1,Ku86,NFIV

Human Baculovirus Insect Cells
X-ray repair cross-complementing protein 5, also known as 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 8 kDa subunit, CTC box-binding factor 85 kDa subunit, DNA repair protein XRCC5, Lupus Ku autoantigen protein p86, TLAA and XRCC5, is a nucleus and chromosome which belongs to the ku8 family. XRCC5 is a single-stranded DNA-dependent ATP-dependent helicase. XRCC5 has a role in chromosome translocation. X-ray repair cross-complementing protein...
TMPH-02570 WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO)

CCN family member 5,Connective tissue growth factor-like pro...

Mouse E. coli
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
TMPH-02314 XRCC5 Protein, Human, Recombinant (His & MBP)

Nuclear factor IV,Lupus Ku autoantigen protein p86,ATP-depen...

Human Baculovirus Insect Cells
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind...
TMPH-02315 XRCC5 Protein, Human, Recombinant (His & Myc)

ATP-dependent DNA helicase 2 subunit 2,XRCC5,Ku86,Nuclear fa...

Human E. coli
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind...
TMPY-02010 DMP1 Protein, Human, Recombinant (His)

ARHR,dentin matrix acidic phosphoprotein 1,ARHP,DMP-1

Human HEK293 Cells
Dentin matrix acidic phosphoprotein (DMP1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. DMP1 contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nu...

重组蛋白

Osteocalcin Protein, Rat, Recombinant (GST)
Cat.No: TMPH-03346
Species: Rat
Expression System: E. coli
Osteocalcin Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02818
Species: Mouse
Expression System: E. coli
Osteocalcin Protein, Chicken, Recombinant (His & KSI)
Cat.No: TMPH-00380
Species: Chicken
Expression System: E. coli
Osteocalcin Protein, Canine, Recombinant (His & KSI)
Cat.No: TMPH-00496
Species: Canine
Expression System: E. coli
WISP2/CCN5 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02569
Species: Mouse
Expression System: P. pastoris (Yeast)
Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His)
Cat.No: TMPY-02287
Species: Human
Expression System: Baculovirus Insect Cells
WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02570
Species: Mouse
Expression System: E. coli
XRCC5 Protein, Human, Recombinant (His & MBP)
Cat.No: TMPH-02314
Species: Human
Expression System: Baculovirus Insect Cells
XRCC5 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02315
Species: Human
Expression System: E. coli
DMP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02010
Species: Human
Expression System: HEK293 Cells
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