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Search Results for " organophosphorus "

Targets Recommended: AChE

21

抑制剂 & 化合物

1

天然产物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T1111	Pralidoxime Chloride 2-PAM chloride,吡啶醛肟甲氯,2-Pyridinealdoxime methochloride,2-PAM (chloride)	AChE	Neuroscience
	Pralidoxime Chloride (2-PAM chloride) 是一种肟类化合物，对中毒乙酰胆碱酯酶具有恢复作用，可用于有机磷中毒的研究。
T20539	Pirimiphos-methyl R 33986,甲基嘧啶磷,AI3-27699,Caswell No. 334B,PP511,Actelic	AChE; Parasite	Microbiology/Virology; Neuroscience
	Pirimiphos-methyl (AI3-27699) 是一种速效有机磷杀虫剂和杀螨剂，对目标生物的乙酰胆碱酯酶有抑制作用。甲基嘧啶磷常用于农粮贮藏过程中甲虫、鼻甲虫、飞蛾和蝽蛄的防治。
T1250	Thio-TEPA Tiofosyl,Triethylenethiophosphoramide,三亚乙基硫代磷酰胺,Tiofosfamid	DNA Alkylator/Crosslinker; DNA Alkylation; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Thio-TEPA (Tiofosyl) 是一种具有抗肿瘤作用的 DNA 烷化剂。
T5844	Tolclofos-methyl	Antibacterial	Microbiology/Virology
	Tolclofos-methyl 是一种有机磷杀菌剂，广泛用于防治土传病害。
T19084	1-Naphthyl acetate	AChE	Neuroscience
	1-Naphthyl acetate 是一种有吸引力的生色底物，用于检测红细胞乙酰胆碱酯酶的活性。它具有检测有机磷农药中毒的潜力。
T40226	FP-Biotin	Others	Others
	FP-biotin is a potent organophosphorus toxicant, ideal for identifying novel biomarkers of organophosphorus toxicant exposure. It measures FAAH, ABHD6, and MAG-lipase activity, specifically in plasma studies, due to the efficient purification of biotinylated peptides through binding to immobilized avidin beads.
T32074	Hgg 12 Hgg-12,Hgg12	Others	Others
	Hgg 12 is used to treat organophosphorus poisoning.
T20729	Vamidothion RP9895,Kilval,Trucidor,RP-9895,RP 10465,RP 9895	Others	Others
	Vamidothion is a polar organophosphorus insecticide and acaricide
T38288	Profenofos	Others	Others
	Profenofos is an acetylcholinesterase-inhibiting organophosphorus pesticide on field crops, vegetables, and fruit crops [1]. [1]. Madhulika Kushwaha, et al. Kushwaha, M., et al.. Profenofos, an Acetylcholinesterase-Inhibiting Organophosphorus Pesticide: A Short Review of Its Usage, Toxicity, and Biodegradation. J Environ Qual.2016 Sep;45(5):1478-1489.
T25539	Iprobenfos Ricid P,Kitazin P,Kitazin L,异稻瘟净,Ricid II	Others	Others
	Iprobenfos (IBP) is used as an organophosphorus pesticide.
T25964	Pirimiphos-ethyl Primicid,Fernex,PP 211,PP-211,PP211	Others	Others
	Pirimiphos-ethyl is used as an organophosphorus pesticide.
T20831	Etrimfos Ekamet,San197,San 197,Satisfar,San-197	Others	Others
	Etrimfos is an organophosphorus insecticide with high efficiency and low toxicity.
T26051	RE 11775 RE-11775,RE11775	Others	Others
	RE 11775 is used as a carbamate insecticide with promising activity against organophosphorus-resistant mosquitoes.
T24664	Propaphos Kayaphos,丙虫磷,Kayphosnac	Others	Others
	Propaphos (Kayaphos) 是一种有机磷类杀虫剂。
T20674	Kitazine Ritacin-P,Ricide,EBP,Ritacin P	Others	Others
	Kitazine is an organophosphorus chemical fungicide. It is mainly used to control rice blast and has a certain effect on rice Sclerotinia sclerotiorum, sheath blight, corn leaf spot, and spot disease.
T15462	Haloxon	Others	Others
	Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants.
T62857	K203	Others	Others
	K203 是一种有效的 tabun 抑制的 AChE 再激活剂，是一种重要的有机磷中毒解毒剂。
T69556	Cyanophos	Others	Others
	Cyanophos is a cholinesterase inhibitor used as an insecticide and avicide; for example, against rice stem borers and house flies. It is part of the chemical class of organophosphorus compounds, and is a yellow to reddish-yellow transparent liquid.
T36058	Dibutyl-3-Hydroxybutyl Phosphate	Others	Others
	Dibutyl 3-hydroxybutyl phosphate is a compound produced from the metabolism of the organophosphorus solvent, tributyl phosphate (TBP). Incubation of goldfish liver microsomes in the presence of NADPH has been shown to convert TBP into dibutyl-3-hydroxybutyl phosphate and dibutyl phosphate. Dibutyl-3-hydroxybutyl phosphate has also been produced during radiolysis of TBP.
T78674	Isopropyl dodec-11-enylfluorophosphonate IDEFP	FAAH	Metabolism; Neuroscience
	Isopropyl dodec-11-enylfluorophosphonate (IDEFP) 为有机磷酯类化合物，能抑制中枢大麻素受体 (cannabinoid receptor) (CB1) 并具有相似的效力抑制FAAH（IC50s = 2 nM）。
T37629	IDFP	Others	Others
	The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). Monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH) hydrolyze 2-AG and AEA, respectively, thus terminating their biological function. IDFP is an organophosphorus compound that dually inhibits MAGL and F...

化合物

Pralidoxime Chloride

Cat.No: T1111

Synonym: 2-PAM chloride,吡啶醛肟甲氯,2-Pyridinealdoxime methochloride,2-PAM (chloride)

Target: AChE

Pirimiphos-methyl

Cat.No: T20539

Synonym: R 33986,甲基嘧啶磷,AI3-27699,Caswell No. 334B,PP511,Actelic

Target: AChE, Parasite

Cat.No: T1250

Synonym: Tiofosyl,Triethylenethiophosphoramide,三亚乙基硫代磷酰胺,Tiofosfamid

Target: DNA Alkylator/Crosslinker, DNA Alkylation, Antibacterial, Antibiotic

Tolclofos-methyl

Cat.No: T5844

Target: Antibacterial

1-Naphthyl acetate

Cat.No: T19084

Target: AChE

Cat.No: T40226

Target: Others

Cat.No: T32074

Synonym: Hgg-12,Hgg12

Target: Others

Cat.No: T20729

Synonym: RP9895,Kilval,Trucidor,RP-9895,RP 10465,RP 9895

Target: Others

Cat.No: T38288

Target: Others

Cat.No: T25539

Synonym: Ricid P,Kitazin P,Kitazin L,异稻瘟净,Ricid II

Target: Others

Pirimiphos-ethyl

Cat.No: T25964

Synonym: Primicid,Fernex,PP 211,PP-211,PP211

Target: Others

Cat.No: T20831

Synonym: Ekamet,San197,San 197,Satisfar,San-197

Target: Others

Cat.No: T26051

Synonym: RE-11775,RE11775

Target: Others

Cat.No: T24664

Synonym: Kayaphos,丙虫磷,Kayphosnac

Target: Others

Cat.No: T20674

Synonym: Ritacin-P,Ricide,EBP,Ritacin P

Target: Others

Cat.No: T15462

Target: Others

Cat.No: T62857

Target: Others

Cat.No: T69556

Target: Others

Dibutyl-3-Hydroxybutyl Phosphate

Cat.No: T36058

Target: Others

Isopropyl dodec-11-enylfluorophosphonate

Cat.No: T78674

Synonym: IDEFP

Target: FAAH

Cat.No: T37629

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T7192	Diethyl phosphate Diethyl phosphoric acid,磷酸二乙酯	Others; Endogenous Metabolite	Metabolism; Others
	Diethyl phosphate (Diethyl phosphoric acid) 是一种常用杀虫剂Chlorpyrifos 的代谢或天然降解产物。

天然产物

Diethyl phosphate

Cat.No: T7192

Synonym: Diethyl phosphoric acid,磷酸二乙酯

Target: Others, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02903	PON1 Protein, Mouse, Recombinant Pon1,Aromatic esterase 1,Serum aryldialkylphosphatase 1,Seru...	Mouse	E. coli
	Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification. PON1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 39.4 kDa and the accession number is P52430.
TMPH-02102	PON1 Protein, Human, Recombinant (GST) Serum paraoxonase/arylesterase 1,K-45,Aromatic esterase 1,PO...	Human	E. coli
	Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.

重组蛋白

PON1 Protein, Mouse, Recombinant

Cat.No: TMPH-02903

Species: Mouse

Expression System: E. coli

PON1 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02102

Species: Human

Expression System: E. coli

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