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Search Results for " ofloxacin "

Targets Recommended: Topoisomerase Antibacterial Antibiotic

39

抑制剂 & 化合物

3

天然产物

8

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T0902	Ofloxacin DL8280,菲宁达,Hoe-280,氧氟沙星,Floxin,Tarivid,Oxaldin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Ofloxacin (Oxaldin) 是可抑制细菌DNA 旋转酶的一种氟喹诺酮类抗生素。
T17307	(R)-Ofloxacin DR3354,D-Ofloxacin,DR-3354,DR 3354,(R)-氧氟沙星,(R)-(+)-Ofloxacin,(+)-Ofloxacin	Others	Others
	(R)-Ofloxacin is a R-isomer of Ofloxacin, an antibiotic used to treat a number of bacterial infections.
T36031	Desmethyl Ofloxacin (hydrochloride)	Others	Others
	Desmethyl ofloxacin is a metabolite of the fluoroquinolone antibiotic ofloxacin .1 1.Sudo, K., Okazaki, O., Tsumura, M., et al.Isolation and identification of metabolites of ofloxacin in rats, dogs and monkeysXenobiotica16(8)725-732(1986)
T71982	Ofloxacin HCl	Others	Others
	Ofloxacin HCl is a synthetic fluoroquinolone ( FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
T64502	(S)-Decarboxyl ofloxacin	Others	Others
	(S)-Decarboxyl ofloxacin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64502。
T71310	DS 4574	Others	Others
	DS 4574 is a peptidoleukotriene receptor antagonist used in treatment of hypersensitivity.
T1451	Levofloxacin hydrate 左氧氟沙星半水合物,Levaquin hydrate,Cravit hydrate,Quixin hydrate,Levofloxacin Hemihydrate,Tavanic hydrate,Iquix hydrate	DNA gyrase; Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Levofloxacin hydrate (Cravit hydrate) 是抗生素化合物，抑制细菌DNA 旋转酶活性。
T8747	Levofloxacin hydrochloride	DNA gyrase; Topoisomerase	DNA Damage/DNA Repair
	Levofloxacin hydrochloride 是一种广谱的第三代氟喹诺酮类抗生素，是氧氟沙星的光学活性 L-异构体，具有抗菌活性。左氧氟沙星通过细菌细胞壁扩散并通过抑制 DNA 促旋酶（细菌拓扑异构酶 II）起作用，这是一种 DNA 复制、RNA 转录和细菌 DNA 修复所需的酶。 DNA 促旋酶活性的抑制导致细菌细胞生长受阻。
T1617	Enrofloxacin 恩诺沙星,BAY-Vp2674,PD160788	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Enrofloxacin (BAY-Vp2674) 是一种作用于支原体的抗生素，MIC90为 0.312 μg/mL。
T7865	Danofloxacin 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine	Others; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Danofloxacin (Danofloxacin free base) free base 是一种具有口服活性第三代氟喹诺酮抗菌剂，对大多数革兰氏阴性和革兰氏阳性细菌，支原体和衣原体物种具有广谱的活性，并通过抑制细菌的 DNA 回转酶发挥抗菌作用。它可用于牛，猪和鸡呼吸道疾病的研究。
T3117	Marbofloxacin 马波沙星,Marbofloxacine,Zeniquin,Marbocyl	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Marbofloxacin (Zeniquin) 是一种具有口服活性的氟喹诺酮类广谱抗菌剂。它可研究革兰氏阳性和革兰氏阴性细菌以及支原体引起的感染。
T1733	Ciprofloxacin EP IMpurity A Q-Acid,Fluoroquinolonic Acid,环丙羧酸,Ciprofloxacin Impurity A	Antibiotic	Microbiology/Virology
	Ciprofloxacin EP IMpurity A (Fluoroquinolonic Acid) 是一种抗生素和抗菌剂。
T8606	n-acetylciprofloxacin N-乙酰基环丙沙星,3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1	Others	Others
	n-acetylciprofloxacin (3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1) 是 H37Rv 的抑制剂。
T0250	Ciprofloxacin monohydrochloride Bay-09867 (hydrochloride),Ciprofloxacin HCl,盐酸环丙沙星,环丙沙星盐酸盐,Ciprofloxacin hydrochloride	DNA gyrase; Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) 是一种高抗菌活性的氟喹诺酮类抗生素。
T1640	Ciprofloxacin Ciproxan,环丙沙星,Ciprobay,Bay o 9867,Bay-09867	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Ciprofloxacin (Bay-09867) 是一种有高抗菌活性的氟喹诺酮类抗生素。
T0116	Balofloxacin	DNA gyrase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Balofloxacin 是一种具有口服活性的氟喹诺酮类抗生素，可通过干扰 DNA 促旋酶来抑制细菌 DNA 的合成，对革兰氏阴性，革兰氏阳性和厌氧菌具有广谱抗菌活性。它可研究呼吸道，肠道和泌尿道感染。
T38003	Levofloxacin N-oxide	Others	Others
	Levofloxacin N-oxide 是从左氧氟沙星中分离出来的杂质。
T11007L	Levofloxacin Hydrochloride Impurity A Levofloxacin Hydrochloride Impurity A(117707-40-1 Free base),左氧氟沙星杂质A(盐酸盐)	Antibacterial	Microbiology/Virology
	Levofloxacin Hydrochloride Impurity A 是一种喹诺酮类药物，具有广谱抗菌作用。
T10420	Avarofloxacin JNJ-Q2	Others	Others
	Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and community-acquired pneumonia and skin structure infections.
T22265	Balofloxacin Dihydrate Neuroquinoron,巴洛沙星/1-环丙基-7-(3-甲氨基-1-哌啶基)-8-甲氧基-6-氟-1,4-二氢-4-氧代-3-喹啉羧酸	Others	Others
	Balofloxacin is a fluoroquinolone antibiotic with oral activity.
T81412	Pradofloxacin	Others	Others
	Pradofloxacin是一种第三代的氟喹诺酮类抗菌化合物。
T1451L	Levofloxacin sodium	Others	Others
	Levofloxacin sodium is a synthetic fluoroquinolones antibacterial. It inhibits the supercoiling activity of bacterial DNA gyrase, so that halting DNA replication.
T66299	Ciprofloxacin lactate	Others	Others
	Ciprofloxacin lactate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66299，CAS号为 97867-33-9。
T13406	Zabofloxacin DW-224a Free base	Others	Others
	Zabofloxacin is a potent and seletive bacterial type II and IV topoisomerases inhibitor, and has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.
T36030	Desethylene Ciprofloxacin (hydrochloride)	Others	Others
	Desethylene ciprofloxacin is a major metabolite of ciprofloxacin . It is also a degradation product of ciprofloxacin that can be created through advanced oxygenation processes as a potential way to remove ciprofloxacin from wastewater. It is also created during degradation of ciprofloxacin by chlorination.
T75290	Enrofloxacin monohydrochloride	Others	Others
	Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) 为一种针对Mycoplasma bovis具有高效抗菌作用的抗生素，MIC90值为0.312 μg/mL。此外，Enrofloxacin monohydrochloride 亦展现出对牛痘病毒的抗病毒活性。
T13406L	Zabofloxacin hydrochloride DW-224a	Raf	MAPK
	Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.
T23703	Alatrofloxacin	Others	Others
	Alatrofloxacin is a prodrug of trovafloxacin.
T29829	Alatrofloxacin Mesylate UNII-2IXX802851,CP 116517,Alatrofloxacin mesylate (USAN),CP 116,517	Others	Others
	Alatrofloxacin Mesylate is the parental prodrug of broad-spectrum antibiotic trovafloxacin.
T38581	Antofloxacin	Others	Others
	Antofloxacin is a well-tolerated, orally active, and broad-spectrum 8-amino-fluoroquinolone compound that exhibits potent antibacterial properties. It demonstrates superior activity against gyrA mutation-positive Helicobacter pylori strains, particularly in strains with mutations in the Asn87 position, when compared to levofloxacin. Additionally, Antofloxacin acts as a weak but reversible inhibitor of CYP1A2 and is clinically used to treat infections caused by various bacterial species.
T72175	Marbofloxacin hydrochloride 盐酸马波沙星	Others	Others
	Marbofloxacin hydrochloride，一种第三代具口服活性的氟喹诺酮类抗菌剂，展现广谱杀菌效能及优良疗效。适用于探究由革兰氏阳性与革兰氏阴性细菌及支原体所引发的感染。
T67345	Enrofloxacin hcl	Others	Others
	Enrofloxacin hydrochloride is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis.
T26638	Antofloxacin Hydrochloride (S)-Antofloxacin hydrochloride,Antofloxacin HCl	Others	Others
	Antofloxacin Hydrochloride, a fluoroquinolone antimicrobial, is used to treat acute exacerbation of chronic bronchitis (AECB), acute pyelonephritis(AP), acute cystitis and multiple folliculitis.
T11007	Desmethyl Levofloxacin	Others	Others
	Desmethyl Levofloxacin is a metabolite of levofloxacin. Levofloxacin is a synthetic fluoroquinolone drug, an antibacterial agent that can inhibit the super-coiling activity of bacterial DNA gyrase and prevent DNA replication.
T67987	ecenofloxacin	Others	Others
	Ecenofloxacin 是一种氟喹诺酮类抗菌药物，对革兰氏阳性、革兰氏阴性和厌氧生物具有有效的抗菌活性。
T30684	Cadrofloxacin CS-940,CS 940,Cadrofloxacin hydrochloride,Caderofloxacin,CS940	Others	Others
	Cadrofloxacin (Caderofloxacin, CS-940) is a novel fluoroquinolone antimicrobial agent.
T27792	L-Alaninol 2-Aminopropanol	Others	Others
	L-Alaninol (2-Aminopropanol)是一种医药中间体，用于制造氧氟沙星。
T13346L	WQ3810 TFA WQ3810 TFA(888032-58-4 Free base),KPI-10 TFA	Antifungal	Microbiology/Virology
	WQ3810 TFA 是一种可口服的氟喹诺酮，具有抗菌活性，对结核分枝杆菌有抑制作用，抑制氧氟沙星耐药麻风分枝杆菌的 DNA 旋转酶活性。
T75296	Pazufloxacin	Others	Others
	Pazufloxacin (T-3761)是氟喹诺酮类广谱抗生素。

化合物

Cat.No: T0902

Synonym: DL8280,菲宁达,Hoe-280,氧氟沙星,Floxin,Tarivid,Oxaldin

Target: Topoisomerase, Antibacterial, Antibiotic

(R)-Ofloxacin

Cat.No: T17307

Synonym: DR3354,D-Ofloxacin,DR-3354,DR 3354,(R)-氧氟沙星,(R)-(+)-Ofloxacin,(+)-Ofloxacin

Target: Others

Desmethyl Ofloxacin (hydrochloride)

Cat.No: T36031

Target: Others

Ofloxacin HCl

Cat.No: T71982

Target: Others

(S)-Decarboxyl ofloxacin

Cat.No: T64502

Target: Others

Cat.No: T71310

Target: Others

Levofloxacin hydrate

Cat.No: T1451

Synonym: 左氧氟沙星半水合物,Levaquin hydrate,Cravit hydrate,Quixin hydrate,Levofloxacin Hemihydrate,Tavanic hydrate,Iquix hydrate

Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic

Levofloxacin hydrochloride

Cat.No: T8747

Target: DNA gyrase, Topoisomerase

Cat.No: T1617

Synonym: 恩诺沙星,BAY-Vp2674,PD160788

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T7865

Synonym: 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine

Target: Others, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T3117

Synonym: 马波沙星,Marbofloxacine,Zeniquin,Marbocyl

Target: Topoisomerase, Antibacterial, Antibiotic

Ciprofloxacin EP IMpurity A

Cat.No: T1733

Synonym: Q-Acid,Fluoroquinolonic Acid,环丙羧酸,Ciprofloxacin Impurity A

Target: Antibiotic

n-acetylciprofloxacin

Cat.No: T8606

Synonym: N-乙酰基环丙沙星,3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1

Target: Others

Ciprofloxacin monohydrochloride

Cat.No: T0250

Synonym: Bay-09867 (hydrochloride),Ciprofloxacin HCl,盐酸环丙沙星,环丙沙星盐酸盐,Ciprofloxacin hydrochloride

Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic

Cat.No: T1640

Synonym: Ciproxan,环丙沙星,Ciprobay,Bay o 9867,Bay-09867

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T0116

Target: DNA gyrase, Antibacterial, Antibiotic

Levofloxacin N-oxide

Cat.No: T38003

Target: Others

Levofloxacin Hydrochloride Impurity A

Cat.No: T11007L

Synonym: Levofloxacin Hydrochloride Impurity A(117707-40-1 Free base),左氧氟沙星杂质A(盐酸盐)

Target: Antibacterial

Cat.No: T10420

Synonym: JNJ-Q2

Target: Others

Balofloxacin Dihydrate

Cat.No: T22265

Synonym: Neuroquinoron,巴洛沙星/1-环丙基-7-(3-甲氨基-1-哌啶基)-8-甲氧基-6-氟-1,4-二氢-4-氧代-3-喹啉羧酸

Target: Others

Cat.No: T81412

Target: Others

Levofloxacin sodium

Cat.No: T1451L

Target: Others

Ciprofloxacin lactate

Cat.No: T66299

Target: Others

Cat.No: T13406

Synonym: DW-224a Free base

Target: Others

Desethylene Ciprofloxacin (hydrochloride)

Cat.No: T36030

Target: Others

Enrofloxacin monohydrochloride

Cat.No: T75290

Target: Others

Zabofloxacin hydrochloride

Cat.No: T13406L

Synonym: DW-224a

Target: Raf

Cat.No: T23703

Target: Others

Alatrofloxacin Mesylate

Cat.No: T29829

Synonym: UNII-2IXX802851,CP 116517,Alatrofloxacin mesylate (USAN),CP 116,517

Target: Others

Cat.No: T38581

Target: Others

Marbofloxacin hydrochloride

Cat.No: T72175

Synonym: 盐酸马波沙星

Target: Others

Enrofloxacin hcl

Cat.No: T67345

Target: Others

Antofloxacin Hydrochloride

Cat.No: T26638

Synonym: (S)-Antofloxacin hydrochloride,Antofloxacin HCl

Target: Others

Desmethyl Levofloxacin

Cat.No: T11007

Target: Others

Cat.No: T67987

Target: Others

Cat.No: T30684

Synonym: CS-940,CS 940,Cadrofloxacin hydrochloride,Caderofloxacin,CS940

Target: Others

Cat.No: T27792

Synonym: 2-Aminopropanol

Target: Others

Cat.No: T13346L

Synonym: WQ3810 TFA(888032-58-4 Free base),KPI-10 TFA

Target: Antifungal

Cat.No: T75296

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T6567	Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Levofloxacin (Fluoroquinolone) 是合成的氟喹诺酮类抗生素，有抑制细菌DNA 旋转酶的超螺旋活性的作用，能阻止DNA 复制。
T8130	Ciprofloxacin hydrochloride monohydrate Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,环丙沙星盐酸盐一水合物,Ceprimax,盐酸环丙沙星(一水物),Ciloxan	Antibacterial; Antibiotic	Microbiology/Virology
	Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) 是一种具有高效抗菌活性的氟喹诺酮类抗生素。
T1276	Danofloxacin mesylate 甲磺酸达氟沙星,CP 76136-27	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Danofloxacin mesylate (CP 76136-27) 是一种兽医用氟喹诺酮类抗菌素。

天然产物

Cat.No: T6567

Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin

Target: Topoisomerase, Antibacterial, Antibiotic

Ciprofloxacin hydrochloride monohydrate

Cat.No: T8130

Synonym: Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,环丙沙星盐酸盐一水合物,Ceprimax,盐酸环丙沙星(一水物),Ciloxan

Target: Antibacterial, Antibiotic

Danofloxacin mesylate

Cat.No: T1276

Synonym: 甲磺酸达氟沙星,CP 76136-27

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0194	Ofloxacin-d8
	Ofloxacin-d8 是 Ofloxacin 的氘代化合物。Ofloxacin 的 CAS 号为 82419-36-1。Ofloxacin是可抑制细菌DNA旋转酶的一种氟喹诺酮类抗生素。
TMIH-0406	Ofloxacin-d3
	Ofloxacin-d3 是 Ofloxacin 的氘代化合物。
TMIJ-0015	Ciprofloxacin-d8 Hydrochloride
	Ciprofloxacin-d8 Hydrochloride 是 Ciprofloxacin Hydrochloride 的氘代化合物。Ciprofloxacin Hydrochloride 的 CAS 号为 93107-08-5。Ciprofloxacin hydrochloride是一种高抗菌活性的氟喹诺酮类抗生素。
TMIJ-0288	Danofloxacin-d3
	Danofloxacin-d3 是 Danofloxacin 的氘代化合物。Danofloxacin 的 CAS 号为 112398-08-0。Danofloxacin free base 是一种具有口服活性第三代氟喹诺酮抗菌剂，对大多数革兰氏阴性和革兰氏阳性细菌，支原体和衣原体物种具有广谱的活性，并通过抑制细菌的 DNA 回转酶发挥抗菌作用。它可用于牛，猪和鸡呼吸道疾病的研究。
TMIH-0154	Ciprofloxacin-d8
	Ciprofloxacin-d8 是 Ciprofloxacin 的氘代化合物。Ciprofloxacin 的 CAS 号为 85721-33-1。Ciprofloxacin是一种有高抗菌活性的氟喹诺酮类抗生素。
T71984	Enrofloxacin-d5
	Enrofloxacin-d5 is intended for use as an internal standard for the quantification of enrofloxacin by GC- or LC-MS. Enrofloxacin is a fluoroquinolone antibiotic. It is active against panels of Campylobacter, E. coli, and Salmonella isolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates of L. intracellularis (MICs = 0.125-0.5 µg/ml). Enrofloxacin inhibits bacterial DNA gyrase. In vivo, enrofloxacin (10 mg/kg) increases survival in a mouse model...
TMID-0195	Levofloxacin-d8
	Levofloxacin-d8 是 Levofloxacin 的氘代化合物。Levofloxacin 的 CAS 号为 100986-85-4。Levofloxacin是合成的氟喹诺酮类抗生素，有抑制细菌DNA旋转酶的超螺旋活性的作用，能阻止DNA复制。
TMIH-0300	Levofloxacin-d3
	Levofloxacin-d3 是 Levofloxacin 的氘代化合物。Levofloxacin 的 CAS 号为 100986-85-4。Levofloxacin是合成的氟喹诺酮类抗生素，有抑制细菌DNA旋转酶的超螺旋活性的作用，能阻止DNA复制。

同位素标记化合物

Cat.No: TMID-0194

Cat.No: TMIH-0406

Ciprofloxacin-d8 Hydrochloride

Cat.No: TMIJ-0015

Danofloxacin-d3

Cat.No: TMIJ-0288

Ciprofloxacin-d8

Cat.No: TMIH-0154

Enrofloxacin-d5

Cat.No: T71984

Levofloxacin-d8

Cat.No: TMID-0195

Levofloxacin-d3

Cat.No: TMIH-0300

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