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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T68192 OK-1035

Others Others
OK-1035 is a potent and selective DNA-PK inhibitor. When a synthetic peptide was used as a substrate, OK-1035 caused 50% inhibition of DNA-PK activity at 8 microM. OK-1035 inhibited the phosphorylation by DNA-PK of consensus peptide as well as that of recombinant human wild type-p53. Kinetic studies indicated that OK-1035 inhibited DNA-PK activity in an ATP-competitive manner.

化合物

OK-1035
Cat.No: T68192
Synonym:
Target: Others
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