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Search Results for " ntpdase "

Targets Recommended: Phosphatase

13

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T77661	h-NTPDase-IN-4	Phosphatase	Metabolism
	h-NTPDase-IN-4 是 NTPDase 的泛抑制剂，对 h-NTPDase1, 1h-NTPDase2, h-NTPDase3, h-NTPDase8具有抑制作用，IC50 分别为 3.58 μM , 10.21 μM , 0.13 μM , 13.57 μM 。
T79607	h-NTPDase-IN-2 hNTPDase-IN-2	Phosphatase	Metabolism
	h-NTPDase-IN-2 是一种广谱 NTPDase 抑制剂，对多种 h-NTPDas 亚型都具有抑制作用。
T79622	h-NTPDase-IN-3	Phosphatase	Metabolism
	h-NTPDase-IN-3 是一种 h-NTPDase 抑制剂，抑制 h-NTPDase1，h-NTPDase2，h-NTPDase3 和 h-NTPDase8。
T61377	NTPDase-IN-1	Others	Others
	NTPDase-IN-1 (compound 5a) is a selective inhibitor of NTPDase enzymes. It shows inhibitory activity against h-NTPDase-1, h-NTPDase-2, and h-NTPDase-8 with IC50 values of 0.05 μM, 0.23 μM, and 0.54 μM, respectively. NTPDase-IN-1 exerts non-competitive inhibition on h-NTPDase-1 and h-NTPDase-2, with a K m value of 21 μM for h-NTPDase-1. This compound is useful for investigating various conditions like cancer, immunologic disorders, and bacterial infections [1].
T62703	NTPDase-IN-2	Others	Others
	NTPDase-IN-2 (化合物 5g) 是一种具有选择性的NTPDase 抑制剂，其对h-NTPDase-2/-8的IC50值分别为 0.04 和 2.27 µM。NTPDase-IN-2 可非竞争性地抑制h-NTPDase-1/-2，其对h-NTPDase-2的Km 值为 74 µM。NTPDase-IN-2 可用于癌症、免疫学疾病以及细菌感染的研究。
T62633	NTPDase-IN-3	Others	Others
	NTPDase-IN-3 (Compound 5e) 是一种 NTPDase 抑制剂，IC50值分别为 0.38 μM (NTPDase3), 0.05 μM (NTPDase8), 0.21 μM (NTPDase1), 1.07 μM (NTPDase2)。NTPDase-IN-3 可用于癌症和血栓形成的研究。
T79491	h-NTPDase-IN-1	Phosphatase	Metabolism
	h-NTPDase-IN-1 (Compound 3i) 是一种针对 h-NTPDase 的抑制剂，对 h-NTPDase1 和 h-NTPDase3 的抑制作用表现在 IC50 值分别为 2.88 μM 和 0.72 μM。该化合物在血栓、炎症、糖尿病及癌症研究领域有潜在应用。
T79623	h-NTPDase-IN-5	Phosphatase	Metabolism
	h-NTPDase-IN-5（化合物3b）是一种NTPDase的泛抑制剂，其IC50s对于h-NTPDase1为1.10 μM，h-NTPDase2为44.73 μM，h-NTPDase3为26.14 μM，h-NTPDase8为0.32 μM。
T79492	h-NTPDase8-IN-1	Phosphatase	Metabolism
	h-NTPDase8-IN-1 是一种特异性氨磺酰苯甲酰胺类 h-NTPDases8 抑制剂（IC 50 = 0.28 ± 0.07 μM）。h-NTPDase8-IN-1 可用于研究 h -NTPDase 表达异常带来的疾病。
T4190	Ticlopidine PCR 5332,Ticlid,噻氯匹定	ATPase; Adiponectin receptor	GPCR/G Protein; Membrane transporter/Ion channel
	Ticlopidine (PCR 5332) 是抗血栓前药。它是CYP2C19人肝细胞色素的抑制剂，抑制 CYP2C9 及 CYP3A4。他是变构CD39的非竞争性抑制剂，能够阻断 NTPDase 同工酶，对NTPDase2和NTPDase3的IC50分别为 170 µM 和 149 µM。
T12519	Sodium metatungstate POM-1,聚钨酸钠,Sodium polyoxotungstate	Phosphatase	Metabolism
	Sodium metatungstate (Sodium polyoxotungstate) 是一种外核苷三磷酸二磷酸水解酶抑制剂，能够抑制 ATP 的分解，并阻断中枢突触传递，这是独立于抑制 NTPDase 而发挥作用的。
T23194	PSB069 PSB 069	Others	Others
	NTPDase inhibitor
T23193	PSB 06126	Others	Others
	NTPDase 3 inhibitor

化合物

h-NTPDase-IN-4

Cat.No: T77661

Target: Phosphatase

h-NTPDase-IN-2

Cat.No: T79607

Synonym: hNTPDase-IN-2

Target: Phosphatase

h-NTPDase-IN-3

Cat.No: T79622

Target: Phosphatase

Cat.No: T61377

Target: Others

Cat.No: T62703

Target: Others

Cat.No: T62633

Target: Others

h-NTPDase-IN-1

Cat.No: T79491

Target: Phosphatase

h-NTPDase-IN-5

Cat.No: T79623

Target: Phosphatase

h-NTPDase8-IN-1

Cat.No: T79492

Target: Phosphatase

Cat.No: T4190

Synonym: PCR 5332,Ticlid,噻氯匹定

Target: ATPase, Adiponectin receptor

Sodium metatungstate

Cat.No: T12519

Synonym: POM-1,聚钨酸钠,Sodium polyoxotungstate

Target: Phosphatase

Cat.No: T23194

Synonym: PSB 069

Target: Others

Cat.No: T23193

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02808	CD39 Protein, Mouse, Recombinant (His) NTPDase-1,AA408691,ectonucleoside triphosphate diph...	Mouse	Baculovirus Insect Cells
	CD39 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51 kDa and the accession number is P55772.
TMPY-02639	ENTPD3 Protein, Human, Recombinant (His) ectonucleoside triphosphate diphosphohydrolase 3,HB6,NTP...	Human	Baculovirus Insect Cells
	ENTPD3 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51 kDa and the accession number is O75355.
TMPY-02929	ENTPD2 Protein, Human, Recombinant (aa 29-460, His) ectonucleoside triphosphate diphosphohydrolase 2,NTPDase...	Human	Baculovirus Insect Cells
	NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii in...
TMPY-01126	CD39 Protein, Human, Recombinant (His) SPG64,CD39,ectonucleoside triphosphate diphosphohydrolase 1,...	Human	Baculovirus Insect Cells
	CD39 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51.8 kDa and the accession number is P49961-1.
TMPY-02758	ENTPD5 Protein, Human, Recombinant (His) NTPDase-5,ectonucleoside triphosphate diphosphohydr...	Human	Baculovirus Insect Cells
	ENTPD5 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 47 kDa and the accession number is O75356.
TMPY-06110	ENTPD3 Protein, Mouse, Recombinant (His) HB6,ectonucleoside triphosphate diphosphohydrolase 3,Cd39l3,...	Mouse	Baculovirus Insect Cells
	ENTPD3 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.9 kDa and the accession number is NP_848791.3.
TMPY-04276	ENTPD5 Protein, Mouse, Recombinant (His) NTPDase-5,AI196558,ER-UDPase,ectonucleoside triphos...	Mouse	Baculovirus Insect Cells
	ENTPD5 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q9WUZ9.

重组蛋白

CD39 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02808

Species: Mouse

Expression System: Baculovirus Insect Cells

ENTPD3 Protein, Human, Recombinant (His)

Cat.No: TMPY-02639

Species: Human

Expression System: Baculovirus Insect Cells

ENTPD2 Protein, Human, Recombinant (aa 29-460, His)

Cat.No: TMPY-02929

Species: Human

Expression System: Baculovirus Insect Cells

CD39 Protein, Human, Recombinant (His)

Cat.No: TMPY-01126

Species: Human

Expression System: Baculovirus Insect Cells

ENTPD5 Protein, Human, Recombinant (His)

Cat.No: TMPY-02758

Species: Human

Expression System: Baculovirus Insect Cells

ENTPD3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06110

Species: Mouse

Expression System: Baculovirus Insect Cells

ENTPD5 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04276

Species: Mouse

Expression System: Baculovirus Insect Cells

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