Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T28960 |
Thaspine HCl
Thaspine,Thaspine HCl, NSC 135784,NSC-135784,NSC135784 |
Others | Others |
Thaspine is a potent topoisomerase IB inhibitor. Taspine downregulates VEGF expression and inhibits proliferation of vascular endothelial cells through PI3 kinase and MAP kinase signaling pathways. | |||
T20656 |
Verapamil
NSC 135784,维拉帕米,NSC-135784,CP-16533-1,(±)-Verapamil |
P450; Calcium Channel; P-gp | Membrane transporter/Ion channel; Metabolism; Neuroscience |
Verapamil (CP-16533-1) 是一种非二氢吡啶类钙通道阻滞剂,一种 P-gp 抑制剂,也是一种 CYP3A4 抑制剂,具有口服活性。Verapamil 可以用于治疗高血压、心绞痛、心肌梗塞等。 |