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Search Results for " nsaid "

Targets Recommended: Apoptosis BCL

92

抑制剂 & 化合物

2

天然产物

1

化合物库

3

重组蛋白

9

同位素标记化合物

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Cat. No.	Product Name
L4700	免疫/炎症分子化合物库		4720 compounds
	4720 种具有抗炎症活性的化合物的特有集合，可用于高通量筛选和高内涵筛选；

化合物库

免疫/炎症分子化合物库

Cat.No: L4700

Compounds: 4720

Cat. No.	Product Name	Target	Signaling Pathways
T21823	Se-Aspirin Se-NSAID-8	Apoptosis; BCL	Apoptosis
	Se-Aspirin (Se-NSAID-8) 具有抗癌活性和胃保护作用，抑制促炎和促生存NF-ĸB通路的激活，抑制NF-ĸB下游抗凋亡靶标（如Bcl-xL、Mcl-1和存活素）的表达。Se-Aspirin 诱导细胞周期停滞和细胞凋亡的激活，可加速溃疡愈合，可用于研究胰腺癌和结直肠癌。
T2553	Etofenamate	COX	Immunology/Inflammation; Neuroscience
	Etofenamate 是非甾体类抗炎小分子，也是非选择性的 COX 抑制剂，具有抗风湿和解热抗炎作用，可用于缓解疼痛、关节炎等炎症相关疾病的研究。
T2550	Tolmetin Tolectin,托麦汀	COX	Immunology/Inflammation; Neuroscience
	Tolmetin (Tolectin) 是非甾体类抗炎药，是可口服的 COX 抑制剂，对人 COX-1 和 COX-2 的 IC50值分别为 0.35 和 0.82 µM。
T10152	4-Methylamino antipyrine	COX; Drug Metabolite	Immunology/Inflammation; Metabolism; Neuroscience
	4-Methylamino antipyrine 是 Metamizole 的活性代谢产物，可用于疼痛和发烧的研究。Metamizole 是吡唑啉酮类非甾体抗炎药，可抑制COX。
T0291	Flurbiprofen 氟比洛芬,dl-Flurbiprofen	Apoptosis; COX; MRP	Apoptosis; Immunology/Inflammation; Neuroscience
	Flurbiprofen (dl-Flurbiprofen) 是一种高效的，具有口服活性的非甾体抗炎化合物，有退热止痛活性, 常用于炎症性疾病的研究。它是一种非选择性的环氧合酶抑制剂，可研究结肠癌。
T1432	Phenylbutazone Butazolidine,保泰松	COX	Immunology/Inflammation; Neuroscience
	Phenylbutazone (Butazolidine) 是是非甾体类抗炎药，前列腺素 H 合酶过氧化物酶的还原辅助因子，可诱导肌肉盲样蛋白 1 表达，有用于强直性脊柱炎的研究潜力。
T5460	Mofezolac 莫苯唑酸,莫非佐酸	COX	Immunology/Inflammation; Neuroscience
	Mofezolac 是一种非甾体类抗炎药，可缓解疼痛并具有抗炎活性，抑制 COX-1和COX-2的IC50为 1.44 和 447 nM。
T8550	NDMC101	Others; NF-κB; Proteasome	NF-κB; Others; Proteases/Proteasome; Ubiquitination
	NDMC101 是有效的破骨细胞形成抑制剂，通过下调 NFATc1 调控基因表达抑制破骨细胞分化。它与 DPP4底物相似，通过抑制DPP4抑制早期 T 细胞激活。它能够用于骨疾病的研究，如类风湿关节炎、滑膜炎等。
T6737	Zaltoprofen CN100,扎托布洛芬,Soleton	COX	Immunology/Inflammation; Neuroscience
	Zaltoprofen (Soleton) 是一种非甾体类抗炎剂，具有强大的抗炎作用和对炎性疼痛的止痛作用。它是可口服的COX-2抑制剂，对COX-1和COX-2的IC50值分别为 1.3 和 0.34 μM。
T21294	Polmacoxib CG-100649,帕马考昔,CG100649,CG 100649	COX; Carbonic Anhydrase	Immunology/Inflammation; Metabolism; Neuroscience
	Polmacoxib (CG 100649) 是一流的 NSAID 候选药物，是碳酸酐酶 (CA) 和 COX-2 的双重抑制剂。它在小鼠模型中抑制大肠腺瘤和肿瘤生长。
T0463	Loxoprofen Loxoprofene,洛索洛芬,Loxoprofeno,Koloxo	COX	Immunology/Inflammation; Neuroscience
	Loxoprofen (Koloxo) 是一种非甾体类抗炎药，具有解热作用，可用于缓解疼痛的研究。它是非选择性COX 抑制剂，对 COX-1 和 COX-2 的IC50分别为 6.5 和 13.5 μM。
T0159	Pranoprofen 普拉洛芬,Pyranoprofen	Apoptosis; COX; PGE Synthase; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Pranoprofen (Pyranoprofen) 可抑制COX1/2酶，阻断花生四烯酸转化为二十烷醇，减少前列腺素的合成。它是一种用于眼科的非甾体抗炎试剂。
T27635	Isoxepac 伊索克酸,Olopatadine USP Related Compound C	Others	Others
	Isoxepac (Olopatadine USP Related Compound C) 是非甾体抗炎剂，显示出抗炎、镇痛和解热活性，已在多种动物模型中进行了相关研究。
T9042	Teriflunomide impurity 3 4-Amino-N-(4-trifluoromethylphenyl)benzamide	COX	Immunology/Inflammation; Neuroscience
	Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) 是一种选择性COX-1抑制剂，IC50为 30 µM。
T36683	Vedaprofen Quadrisol,PM 150,维达洛芬,CERM 10202	COX; Antibacterial; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Vedaprofen (PM 150) 抑制 COX-1 并通过抗炎活性减少前列腺素 H2 的合成。 Vedaprofen 是一种大肠杆菌滑动钳抑制剂，IC50 为 222 μM，Ki 为 131 μM。
T0708	Oxaprozin 奥沙普秦,Oxaprozinum,Wy21743	NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	Oxaprozin (Oxaprozinum) 是 COX-1和 COX-2的抑制剂，还能抑制 NF-κB 的活化，对人类血小板 COX-1 和 IL-1 刺激的人类滑膜细胞 COX-2 的 IC50值分别为 2.2 和 36 μM。
T21412	Ketorolac Toradol,Sprix,Acuvail,Macril,酮咯酸,Acular	COX	Immunology/Inflammation; Neuroscience
	Ketorolac (Acuvail) 是非甾体抗炎剂，是非选择性的COX 抑制剂，对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
T0459	Sulindac Arthrocine,MK-231,舒林酸,Clinoril,Sulindac sulfoxide	COX; Autophagy	Autophagy; Immunology/Inflammation; Neuroscience
	Sulindac (Sulindac sulfoxide) 是一种非甾体类抗炎剂，可抑制COX-2的活性，也可抑制 COX-2 的过表达。它是一种亚磺酰基茚衍生物前药，具有潜在的抗肿瘤活性。
T22307	Diclofenac Epolamine diclofenac hydroxyethylpyrrolidine,DHEP,2-((2,6-二氯苯基)氨基)苯乙酸 1-吡咯烷乙醇盐,DIEP	Others	Others
	Diclofenac Epolamine (DHEP) 是一种非甾体抗炎药 (NSAID)，具有镇痛和解热作用。
T19672	Amtolmetin guacil MED 15,MED15,ST679,呱氨托美丁,ST-679,ST 679,MED-15	COX	Immunology/Inflammation; Neuroscience
	Amtolmetin guacil (ST-679) 抑制前列腺素合成和环氧合酶。 Amtolmetin guacil 具有与托美汀类似的 NSAID 特性，具有额外的镇痛、解热和胃保护特性。
T6498	Fenoprofen calcium hydrate Feprona dihydrate,Fenoprofen calcium salt dihydrate,Progesic dihydrate,非诺洛芬钙二水合物	Apoptosis; Others; COX	Apoptosis; Immunology/Inflammation; Neuroscience; Others
	Fenoprofen calcium hydrate (Progesic dihydrate) 是一非甾体类抗炎症化合物。
T10355	Apyramide	COX	Immunology/Inflammation; Neuroscience
	Apyramide 是一种抗炎试剂 (NSAID)，是吲哚美辛的前药。Indomethacin 是一种强效的、血脑通透的、非选择性的 COX1 和 COX2 抑制剂。
T1421	Aceclofenac 醋氯芬酸,Preservex,Airtal	COX	Immunology/Inflammation; Neuroscience
	Aceclofenac (Preservex) 是一种可口服的非甾体抗炎药，可用于缓解疼痛、骨关节炎、强直性脊柱炎、类风湿性关节炎的研究。
T22437	Tazofelone LY-213829	Others	Others
	Tazofelone (LY-213829) 是环氧合酶-II (COX-II) 抑制剂。在 CYP3A 介导下，Tazofelone 可转化为亚砜和喹啉代谢物，可用于研究炎症性肠病。
T7207	FK 3311 N-[4-乙酰基-2-(2,4-二氟苯氧基)苯基]-甲烷磺酰胺,FK-3311,COX-2 Inhibitor V	COX	Immunology/Inflammation; Neuroscience
	FK 3311 (COX-2 Inhibitor V) 是一种细胞渗透性和口服磺胺类药物，可作为 COX-2 抑制剂和非甾体抗炎药。
T37482	Diclofenac methyl ester	Others	Others
	Diclofenac methyl ester 是双氯芬酸(diclofenac)的疏水性前药形式，它是一种非甾体抗炎药 (NSAID)。它比双氯芬酸更易溶于肉豆蔻酸异丙酯，但毒性更高。
T0448	(S)-(+)-Ibuprofen 左旋布洛芬,Dexibuprofen,(S)-Ibuprofen,(S)-(+)-布洛芬	BCL; Thrombin; Cysteine Protease; COX; PPAR	Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; Proteases/Proteasome
	(S)-(+)-Ibuprofen (Dexibuprofen) 是 Ibuprofen 的 S(+)-对映异构体，能够有效的抑制COX-1(IC50:2.1 μM)和COX-2(IC50:1.6 μM)，。它具有抗癌、退热、止痛，抗炎的效果。
T4542	Clonixin Clonixic acid,氯尼辛	Others	Others
	Clonixin (Clonixic acid) 是一种非甾体抗炎药，具有口服活性。
T0055	Glafenine Glafenin,格拉非宁	COX	Immunology/Inflammation; Neuroscience
	Glafenine (Glafenin) 是一种可用于缓解疼痛研究的非甾体抗炎药。
T1325	Carprofen 卡洛芬,Ridamyl,Imadyl,Rimadyl	FAAH; COX; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; Neuroscience
	Carprofen (Ridamyl) 是多靶点FAAH/COX 抑制剂，能够抑制 COX-2，COX-1 和 FAAH 的活性，IC50值分别为 3.9 μM，22.3 μM 和 78.6 μM。它是一种丙酸衍生物和非甾体抗炎药，具有抗炎、镇痛和解热活性。
T7363	Ibuprofen Piconol U75630,匹美诺芬,布洛芬吡啶甲醇	Others	Others
	Ibuprofen Piconol (U75630) 是非甾体抗炎药物，局部使用可缓解原发性热灼伤和晒伤。
T1394	Ibuprofen Brufen,(±)-Ibuprofe,布洛芬,Motrin,Advil	COX	Immunology/Inflammation; Neuroscience
	Ibuprofen (Advil) 是一种丙酸衍生物和非甾体抗炎药 (NSAID)，具有抗炎、镇痛和解热作用。它是COX-1和COX-2的抑制剂，IC50值分别为 13 和 370 μM，导致前列腺素和血栓素前体的形成减少。
T0432	Diclofenac diethylamine	Apoptosis; COX	Apoptosis; Immunology/Inflammation; Neuroscience
	Diclofenac diethylamine 是非选择性抗炎剂，通过活化 caspase 级联反应来诱导神经干细胞凋亡。它是一种COX 抑制剂，在 CHO 细胞中，对人COX-1和COX-2的IC50值分别为 4 和 1.3 nM。它对绵羊COX-1和COX-2的IC50值分别为 5.1 μM 和0.84 μM。
T1582	Naproxen 萘普生,(S)-Naproxen	COX; Autophagy	Autophagy; Immunology/Inflammation; Neuroscience
	Naproxen ((S)-Naproxen) 是COX-1和COX-2的抑制剂，在细胞试验中IC50值分别为8.72 和5.15 μM。它是丙酸衍生物和非甾体抗炎药，具有抗炎、解热和镇痛活性。
T1574	Etoricoxib Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine,依托考昔	COX	Immunology/Inflammation; Neuroscience
	Etoricoxib (MK-663) 是一种合成的非甾体抗炎药 (NSAID)，具有解热、镇痛和潜在的抗肿瘤特性。它是可口服的选择性 COX-2抑制剂，对人全血 COX-2 和 COX-1 的 IC50值分别为 1.1 和 116 μM。
T7882	Indomethacin farnesil 吲哚美辛法呢酯,Infree	Others; COX; Autophagy	Autophagy; Immunology/Inflammation; Neuroscience; Others
	Indomethacin farnesil (Infree) 是具有口服活性的 Indomethacin 前药，可通过干扰溶酶体的正常功能来破坏自噬流，有抗炎和抗风湿作用。它是一种可透过血脑屏障的，非选择性的 COX1和 COX2抑制剂，在 CHO 细胞中，对人 COX-1 和 COX-2 的IC50值分别为 18 nM 和 26 nM。
T0498	Salsalate Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171,双水杨酸酯	Reactive Oxygen Species; COX	Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Salsalate (Sasapyrine) 是一种有效的抗风湿药物，是一种非乙酰化水杨酸盐，可以绕过胃的吸收，也可以避免环氧合酶的抑制。它具有抗炎活性，降低血糖水平、胰岛素抵抗和细胞因子表达，可用于研究 2 型糖尿病。
T4545	Propacetamol Hydrochloride 盐酸丙帕他莫,Propacetamol HCL	Others	Others
	Propacetamol Hydrochloride (Propacetamol HCL) 是 paracetamol(acetaminophen) 的前药，具有改善的水溶性。当口服非甾体抗炎药不合适或矛盾时，丙帕西莫是一种静脉给药的镇痛药。
T1555	Diclofenac sodium GP 45840,双氯芬酸钠	Apoptosis; COX	Apoptosis; Immunology/Inflammation; Neuroscience
	Diclofenac sodium (GP 45840) 是一种非选择性抗炎剂，是 COX 抑制剂，在 CHO 细胞中，对人 COX-1 和 COX-2 的 IC50值分别为 4 和 1.3 nM。它对绵羊 COX-1 和 COX-2 的 IC50值分别为 5.1 μM，0.84 μM。它通过活化 caspase 级联反应来诱导神经干细胞凋亡。
T6424	Bromfenac Sodium AHR 10282B,Bronuck,AHR 10282R,溴芬酸钠	COX	Immunology/Inflammation; Neuroscience
	Bromfenac Sodium (AHR 10282R) 是可口服的COX 抑制剂，抑制COX-1和COX-2的IC50值分别为 5.56 和 7.45 nM。它是溴化非甾体类抗炎药，通常用于白内障的术后炎症和疼痛以及假晶状体囊状黄斑水肿的研究。
T68155	Tebufelone	Prostaglandin Receptor; LTR	GPCR/G Protein; Immunology/Inflammation
	Tebufelone 是一种体外高效的CO 抑制剂，是一种新型的非甾体抗炎药（NSAID），属于二叔丁基苯酚（DTBP）类，在各种动物模型中显示出强大的抗炎、镇痛和抗网膜炎特性。Tebufelone 能有效地抑制前列腺素（PGE2）的形成，阻止大鼠巨噬细胞（IC50 = 20 microM）和人类全血（IC50 = 22 microM）中脂氧酶途径的产物[白三烯（LTB4）]的体外形成。
T0219	Valdecoxib 伐地考昔,代他考昔,SC 65872	COX	Immunology/Inflammation; Neuroscience
	Valdecoxib (SC 65872) 是可口服的高选择性 COX-2抑制剂，对 COX-2 和 COX-1 的 IC50值分别为 5 nM 和 140 μM，可用于治疗骨关节炎、类风湿性关节炎以及痛经和经期症状。
T1002	Etodolac Ultradol,AY-24236,依托度酸,Etodolic acid,Lodine	Retinoid Receptor; COX	Immunology/Inflammation; Metabolism; Neuroscience
	Etodolac (AY-24236) 是一种吡喃羧酸和非甾体抗炎药，具有解热和镇痛活性，对 COX 的 IC50为53.5 nM。
T0839	Ketoprofen 酮基布洛芬,RP-19583,酮洛芬	Apoptosis; COX; MRP	Apoptosis; Immunology/Inflammation; Neuroscience
	Ketoprofen (RP-19583) 是一种非甾体抗炎剂，能够有效地抑制COX 的活性，在人血单核细胞中，对 COX-1 和 COX-2 的IC50值分别为 2 nM 和 26 nM。
T2403	Bromfenac sodium hydrate Bromfenac sodium,Bromfenac monosodium salt sesquihydrate,溴芬酸钠	COX	Immunology/Inflammation; Neuroscience
	Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) 是一种可口服的 COX 抑制剂，抑制 COX-1和COX-2的IC50值分别为 5.56 和 7.45 nM。它是一种溴化非甾体类抗炎药，有用于白内障的术后炎症和疼痛以及假晶状体囊状黄斑水肿的研究。
T70843	Orazipone	Others	Others
	Orazipone inhibits cytokine production and histamine release; an NSAID.
T40453	Bumadizone	Others	Others
	Bumadizone is a non-steroidal anti-inflammatory drug (NSAID) and can relieve pain.
T26618	Aminoprofen AU-7801,Mabuprofen	Others	Others
	Aminoprofen is a non selective COX inhibitor and used as a NSAID (non-steroidal anti-inflammatory drug).
T27844	Lonazolac Calcium Floxan,Irritren	Others	Others
	Lonazolac Calcium, a nonsteroidal anti-inflammatory drug (NSAID), is used to treat inflammation and pain.
T31817	Flumizole CP-22665,Flumizol,UNII-Y4YQF944N9,Flumizole (USAN/INN),Flumizolum	Others	Others
	Flumizole is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzyme cyclocxygenase (COX).

化合物

Cat.No: T21823

Synonym: Se-NSAID-8

Target: Apoptosis, BCL

Cat.No: T2553

Target: COX

Cat.No: T2550

Synonym: Tolectin,托麦汀

Target: COX

4-Methylamino antipyrine

Cat.No: T10152

Target: COX, Drug Metabolite

Cat.No: T0291

Synonym: 氟比洛芬,dl-Flurbiprofen

Target: Apoptosis, COX, MRP

Cat.No: T1432

Synonym: Butazolidine,保泰松

Target: COX

Cat.No: T5460

Synonym: 莫苯唑酸,莫非佐酸

Target: COX

Cat.No: T8550

Target: Others, NF-κB, Proteasome

Cat.No: T6737

Synonym: CN100,扎托布洛芬,Soleton

Target: COX

Cat.No: T21294

Synonym: CG-100649,帕马考昔,CG100649,CG 100649

Target: COX, Carbonic Anhydrase

Cat.No: T0463

Synonym: Loxoprofene,洛索洛芬,Loxoprofeno,Koloxo

Target: COX

Cat.No: T0159

Synonym: 普拉洛芬,Pyranoprofen

Target: Apoptosis, COX, PGE Synthase, Prostaglandin Receptor

Cat.No: T27635

Synonym: 伊索克酸,Olopatadine USP Related Compound C

Target: Others

Teriflunomide impurity 3

Cat.No: T9042

Synonym: 4-Amino-N-(4-trifluoromethylphenyl)benzamide

Target: COX

Cat.No: T36683

Synonym: Quadrisol,PM 150,维达洛芬,CERM 10202

Target: COX, Antibacterial, Prostaglandin Receptor

Cat.No: T0708

Synonym: 奥沙普秦,Oxaprozinum,Wy21743

Target: NF-κB, COX

Cat.No: T21412

Synonym: Toradol,Sprix,Acuvail,Macril,酮咯酸,Acular

Target: COX

Cat.No: T0459

Synonym: Arthrocine,MK-231,舒林酸,Clinoril,Sulindac sulfoxide

Target: COX, Autophagy

Diclofenac Epolamine

Cat.No: T22307

Synonym: diclofenac hydroxyethylpyrrolidine,DHEP,2-((2,6-二氯苯基)氨基)苯乙酸 1-吡咯烷乙醇盐,DIEP

Target: Others

Amtolmetin guacil

Cat.No: T19672

Synonym: MED 15,MED15,ST679,呱氨托美丁,ST-679,ST 679,MED-15

Target: COX

Fenoprofen calcium hydrate

Cat.No: T6498

Synonym: Feprona dihydrate,Fenoprofen calcium salt dihydrate,Progesic dihydrate,非诺洛芬钙二水合物

Target: Apoptosis, Others, COX

Cat.No: T10355

Target: COX

Cat.No: T1421

Synonym: 醋氯芬酸,Preservex,Airtal

Target: COX

Cat.No: T22437

Synonym: LY-213829

Target: Others

Cat.No: T7207

Synonym: N-[4-乙酰基-2-(2,4-二氟苯氧基)苯基]-甲烷磺酰胺,FK-3311,COX-2 Inhibitor V

Target: COX

Diclofenac methyl ester

Cat.No: T37482

Target: Others

(S)-(+)-Ibuprofen

Cat.No: T0448

Synonym: 左旋布洛芬,Dexibuprofen,(S)-Ibuprofen,(S)-(+)-布洛芬

Target: BCL, Thrombin, Cysteine Protease, COX, PPAR

Cat.No: T4542

Synonym: Clonixic acid,氯尼辛

Target: Others

Cat.No: T0055

Synonym: Glafenin,格拉非宁

Target: COX

Cat.No: T1325

Synonym: 卡洛芬,Ridamyl,Imadyl,Rimadyl

Target: FAAH, COX, Autophagy

Ibuprofen Piconol

Cat.No: T7363

Synonym: U75630,匹美诺芬,布洛芬吡啶甲醇

Target: Others

Cat.No: T1394

Synonym: Brufen,(±)-Ibuprofe,布洛芬,Motrin,Advil

Target: COX

Diclofenac diethylamine

Cat.No: T0432

Target: Apoptosis, COX

Cat.No: T1582

Synonym: 萘普生,(S)-Naproxen

Target: COX, Autophagy

Cat.No: T1574

Synonym: Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine,依托考昔

Target: COX

Indomethacin farnesil

Cat.No: T7882

Synonym: 吲哚美辛法呢酯,Infree

Target: Others, COX, Autophagy

Cat.No: T0498

Synonym: Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171,双水杨酸酯

Target: Reactive Oxygen Species, COX

Propacetamol Hydrochloride

Cat.No: T4545

Synonym: 盐酸丙帕他莫,Propacetamol HCL

Target: Others

Diclofenac sodium

Cat.No: T1555

Synonym: GP 45840,双氯芬酸钠

Target: Apoptosis, COX

Bromfenac Sodium

Cat.No: T6424

Synonym: AHR 10282B,Bronuck,AHR 10282R,溴芬酸钠

Target: COX

Cat.No: T68155

Target: Prostaglandin Receptor, LTR

Cat.No: T0219

Synonym: 伐地考昔,代他考昔,SC 65872

Target: COX

Cat.No: T1002

Synonym: Ultradol,AY-24236,依托度酸,Etodolic acid,Lodine

Target: Retinoid Receptor, COX

Cat.No: T0839

Synonym: 酮基布洛芬,RP-19583,酮洛芬

Target: Apoptosis, COX, MRP

Bromfenac sodium hydrate

Cat.No: T2403

Synonym: Bromfenac sodium,Bromfenac monosodium salt sesquihydrate,溴芬酸钠

Target: COX

Cat.No: T70843

Target: Others

Cat.No: T40453

Target: Others

Cat.No: T26618

Synonym: AU-7801,Mabuprofen

Target: Others

Lonazolac Calcium

Cat.No: T27844

Synonym: Floxan,Irritren

Target: Others

Cat.No: T31817

Synonym: CP-22665,Flumizol,UNII-Y4YQF944N9,Flumizole (USAN/INN),Flumizolum

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3S0509	Gaultherin	COX	Immunology/Inflammation; Neuroscience
	Gaultherin 是一种分离自 Gaultheria yunnanensis 中的天然水杨酸酯衍生物。它是一种非甾体类抗炎药，具有止痛和抗炎作用，与 Aspirin 相比没有胃溃疡作用。
T1468	Lornoxicam Ro 13-9297,Chlortenoxicam,TS110,氯诺昔康	COX; Endogenous Metabolite	Immunology/Inflammation; Metabolism; Neuroscience
	Lornoxicam (Chlortenoxicam) 是一种新型非甾体抗炎药，是高活性 COX-1 和 COX-2 抑制剂，IC50 分别为 5 和 8 nM。

天然产物

Cat.No: T3S0509

Target: COX

Cat.No: T1468

Synonym: Ro 13-9297,Chlortenoxicam,TS110,氯诺昔康

Target: COX, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01243	GDF-15 Protein, Rat, Recombinant (His) GDF-15,PDF,PTGF-beta,MIC-1,MIC1,GDF15,PTGFBPTGF-beta,NAG-1,P...	Rat	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6.
TMPK-00569	GDF-15 Protein, Canine, Recombinant (His) GDF15,MIC1,MIC-1,PLAB,GDF-15,PDF,PTGFB,PTGF-beta,RG-1,Placen...	Canine	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.12 kDa and the accession number is A0A8C0TNP6.
TMPK-00196	GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated NAG-1,Placental TGF-beta,PTGFBPTGF-β,PDF,Placental TGF-β,PTG...	Human	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 15.19 kDa and the accession nu...

重组蛋白

GDF-15 Protein, Rat, Recombinant (His)

Cat.No: TMPK-01243

Species: Rat

Expression System: E. coli

GDF-15 Protein, Canine, Recombinant (His)

Cat.No: TMPK-00569

Species: Canine

Expression System: E. coli

GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00196

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T12336	Oxaprozin D4 Wy-21743 D4	Others	Others
	Oxaprozin D4 is the deuterium labeled Oxaprozin, is a non-steroidal anti-inflammatory drug (NSAID).
TMIJ-0298	Flunixin-d3 (methyl-d3)
	Flunixin-d3 (methyl-d3) 是 Flunixin 的氘代化合物。Flunixin 的 CAS 号为 38677-85-9。
TMID-0276	MAA-d3
	MAA-d3 是 MAA 的氘代化合物。MAA 的 CAS 号为 519-98-2。4-Methylamino antipyrine 是 Metamizole 的活性代谢产物，可用于疼痛和发烧的研究。Metamizole 是吡唑啉酮类非甾体抗炎药，可抑制COX。
TMIH-0290	Ketorolac-d5-P1
	Ketorolac-d5-P1 是 Ketorolac 的氘代化合物。Ketorolac 的 CAS 号为 74103-06-3。Ketorolac 是非甾体抗炎剂，是非选择性的COX抑制剂，对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
TMIH-0291	Ketorolac-d5-P2
	Ketorolac-d5-P2 是 Ketorolac 的氘代化合物。Ketorolac 的 CAS 号为 74103-06-3。Ketorolac 是非甾体抗炎剂，是非选择性的COX抑制剂，对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
TMIJ-0274	Sulindac-d3
	Sulindac-d3 是 Sulindac 的氘代化合物。Sulindac 的 CAS 号为 38194-50-2。Sulindac 是一种非甾体类抗炎剂，可抑制COX-2的活性，也可抑制 COX-2 的过表达。它是一种亚磺酰基茚衍生物前药，具有潜在的抗肿瘤活性。
T71212	Lornoxicam-d4
	Lornoxicam-d4 is intended for use as an internal standard for the quantification of lornoxicam by GC- or LC-MS. Lornoxicam is a COX inhibitor and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties. It inhibits production of thromboxane B2 from arachidonic acid in HEL human erythroleukemic cells, which endogenously express COX-1, as well as inhibits LPS-induced formation of prostaglandin F1α from arachidonic acid in Mono-Mac-6 cells, which endogenously e...
T71303	Flufenamic Acid-d4
	Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 µM for human COX-1 and COX-2, respectively). Flufenamic acid inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner. It inhibits calcium influx induced by fMLP or A23187 in human polymorphonuclear...
T71141	Fenspiride-d5
	Fenspiride-d5 is intended for use as an internal standard for the quantification of fenspiride by GC- or LC-MS. Fenspiride is an antagonist of histamine H1 receptors and a non-steroidal anti-inflammatory drug (NSAID). It inhibits histamine-induced contraction of isolated guinea pig trachea but not histamine-induced inotropy of isolated guinea pig heart. It also inhibits phosphodiesterase 4 (PDE4), PDE5, and PDE3 (IC50s = 69, ~158, and 363 µM, respectively, in isolated human bronchi derived from ...

同位素标记化合物

Cat.No: T12336

Synonym: Wy-21743 D4

Target: Others

Flunixin-d3 (methyl-d3)

Cat.No: TMIJ-0298

Cat.No: TMID-0276

Ketorolac-d5-P1

Cat.No: TMIH-0290

Ketorolac-d5-P2

Cat.No: TMIH-0291

Cat.No: TMIJ-0274

Cat.No: T71212

Flufenamic Acid-d4

Cat.No: T71303

Cat.No: T71141

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