Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3195 |
CVT-313
CVT 313,Cdk2 Inhibitor III,CVT313,NG26 |
CDK | Cell Cycle/Checkpoint |
CVT-313 (NG26) 是一种有效的、选择性的、可逆的和 ATP 竞争性抑制剂,可抑制 CDC5L 磷酸化,对 CDK2的 IC50为 0.5 μM。 | |||
T35423 |
7-oxo Staurosporine
|
Others | Others |
7-oxo Staurosporine is an antibiotic originally isolated from S. platensis with diverse biological activites. It inhibits PKC, PKA, phosphorylase kinase, EGFR, and c-Src in vitro (IC50s = 9, 26, 5, 200, and 800 nM, respectively). 7-oxo Staurosporine induces cell cycle arrest in the G2/M phase in human leukemia K562 cells with a minimal effective dose (MED) of 30 ng/ml. It is cytotoxic to P388 mouse leukemia cells that are resistant and susceptible to doxorubicin . 7-oxo Staurosporine inhibits gr... |