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Search Results for " nf1 "

Targets Recommended: Parasite

17

抑制剂 & 化合物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T15409	GNF179	Parasite	Microbiology/Virology
	GNF179 是8,8-二甲基 IP 类似物。它表现出对多药耐药菌株 W2 的效力，具有良好的体外代谢稳定性和体内口服生物相容性。
TMAZ-0207B	Anti-SERPINF1 Monoclonal Antibody-Biotin
	Anti-SERPINF1 Monoclonal Antibody-Biotin is a Biotin-conjugated humanized rabbit antibody targeting SERPINF1. Anti-SERPINF1 Monoclonal Antibody-Biotin can be used in ELISA, FACS, IF.
TMAZ-0218A6	Anti-C1QTNF1 Monoclonal Antibody-AF647
	Anti-C1QTNF1 Monoclonal Antibody-AF647 is a Biotin-conjugated humanized rabbit antibody targeting C1QTNF1. Anti-C1QTNF1 Monoclonal Antibody-AF647 can be used in ELISA, FACS.
TMAZ-0218A5	Anti-C1QTNF1 Monoclonal Antibody-AF555
	Anti-C1QTNF1 Monoclonal Antibody-AF555 is a Biotin-conjugated humanized rabbit antibody targeting C1QTNF1. Anti-C1QTNF1 Monoclonal Antibody-AF555 can be used in ELISA, FACS.
TMAZ-0218A4	Anti-C1QTNF1 Monoclonal Antibody-AF488
	Anti-C1QTNF1 Monoclonal Antibody-AF488 is a Biotin-conjugated humanized rabbit antibody targeting C1QTNF1. Anti-C1QTNF1 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
TMAZ-0218A	Anti-C1QTNF1 Monoclonal Antibody-APC
	Anti-C1QTNF1 Monoclonal Antibody-APC is a Biotin-conjugated humanized rabbit antibody targeting C1QTNF1. Anti-C1QTNF1 Monoclonal Antibody-APC can be used in ELISA, FACS.
TMAZ-0207A6	Anti-SERPINF1 Monoclonal Antibody-AF647
	Anti-SERPINF1 Monoclonal Antibody-AF647 is a Biotin-conjugated humanized rabbit antibody targeting SERPINF1. Anti-SERPINF1 Monoclonal Antibody-AF647 can be used in ELISA, FACS, IF.
TMAZ-0218B	Anti-C1QTNF1 Monoclonal Antibody-Biotin
	Anti-C1QTNF1 Monoclonal Antibody-Biotin is a Biotin-conjugated humanized rabbit antibody targeting C1QTNF1. Anti-C1QTNF1 Monoclonal Antibody-Biotin can be used in ELISA, FACS.
TMAZ-0207A5	Anti-SERPINF1 Monoclonal Antibody-AF555
	Anti-SERPINF1 Monoclonal Antibody-AF555 is a Biotin-conjugated humanized rabbit antibody targeting SERPINF1. Anti-SERPINF1 Monoclonal Antibody-AF555 can be used in ELISA, FACS, IF.
T11445	GNF179 (Metabolite) GNF179 Metabolite	Others	Others
	GNF179 Metabolite, the derivative of GNF179—an optimized 8,8-dimethyl IP analog—demonstrates significant potency (4.8 nM against the multidrug-resistant W2 strain) alongside in vitro metabolic stability and in vivo oral bioavailability.
T16291	NF157	COX	Immunology/Inflammation; Neuroscience
	NF157 significantly decreases the expression of metalloproteinase (MMP)-3, MMP-13, which can be used in the treatment of osteoarthritis (OA). NF157 is a highly selective nanomolar P2Y11 antagonist (pKi: 7.35). The IC50s are 463 nM, 1811 µM, 170 µM for P2Y
TMAZ-0207A	Anti-SERPINF1 Monoclonal Antibody-APC
	Anti-SERPINF1 Monoclonal Antibody-APC is a Biotin-conjugated humanized rabbit antibody targeting SERPINF1. Anti-SERPINF1 Monoclonal Antibody-APC can be used in ELISA, FACS, IF.
TMAZ-0218P	Anti-C1QTNF1 Monoclonal Antibody-PE
	Anti-C1QTNF1 Monoclonal Antibody-PE is a Biotin-conjugated humanized rabbit antibody targeting C1QTNF1. Anti-C1QTNF1 Monoclonal Antibody-PE can be used in ELISA, FACS.
TP2273	NF110 NF 110	Others	Others
	P2X3 antagonist
TMAZ-0207A4	Anti-SERPINF1 Monoclonal Antibody-AF488
	Anti-SERPINF1 Monoclonal Antibody-AF488 is a Biotin-conjugated humanized rabbit antibody targeting SERPINF1. Anti-SERPINF1 Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
TMAZ-0207P	Anti-SERPINF1 Monoclonal Antibody-PE
	Anti-SERPINF1 Monoclonal Antibody-PE is a Biotin-conjugated humanized rabbit antibody targeting SERPINF1. Anti-SERPINF1 Monoclonal Antibody-PE can be used in ELISA, FACS, IF.
T70287	BMS-186511	Others	Others
	BMS-186511 is a Farnesyltransferase (FT) inhibitor with potential anticancer activity. BMS-186511 is a bisubstrate analogue inhibitor of FT, would inhibit the malignant growth properties of a cell line established from malignant schwannoma of an NF1 patient. Following treatment with BMS-186511 , ST88-14 cells became flat, nonrefractile, were contact-inhibited, and lost their ability to grow in soft agar. BMS-186511 was found to specifically inhibit FT, but not geranylgeranyltransferase I, a clos...

化合物

Cat.No: T15409

Target: Parasite

Anti-SERPINF1 Monoclonal Antibody-Biotin

Cat.No: TMAZ-0207B

Anti-C1QTNF1 Monoclonal Antibody-AF647

Cat.No: TMAZ-0218A6

Anti-C1QTNF1 Monoclonal Antibody-AF555

Cat.No: TMAZ-0218A5

Anti-C1QTNF1 Monoclonal Antibody-AF488

Cat.No: TMAZ-0218A4

Anti-C1QTNF1 Monoclonal Antibody-APC

Cat.No: TMAZ-0218A

Anti-SERPINF1 Monoclonal Antibody-AF647

Cat.No: TMAZ-0207A6

Anti-C1QTNF1 Monoclonal Antibody-Biotin

Cat.No: TMAZ-0218B

Anti-SERPINF1 Monoclonal Antibody-AF555

Cat.No: TMAZ-0207A5

GNF179 (Metabolite)

Cat.No: T11445

Synonym: GNF179 Metabolite

Target: Others

Cat.No: T16291

Target: COX

Anti-SERPINF1 Monoclonal Antibody-APC

Cat.No: TMAZ-0207A

Anti-C1QTNF1 Monoclonal Antibody-PE

Cat.No: TMAZ-0218P

Cat.No: TP2273

Synonym: NF 110

Target: Others

Anti-SERPINF1 Monoclonal Antibody-AF488

Cat.No: TMAZ-0207A4

Anti-SERPINF1 Monoclonal Antibody-PE

Cat.No: TMAZ-0207P

Cat.No: T70287

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01756	Neurofibromin/NF1 Protein, Human, Recombinant (His & Myc) Neurofibromin,Neurofibromatosis-related protein NF-...	Human	E. coli
	Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity. Neurofibromin/NF1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.7 kDa and the accession number is P21359.
TMPH-01267	RNF13 Protein, Human, Recombinant (His & Myc) RING finger protein 8,RNF8,E3 ubiquitin-protein lig...	Human	E. coli
	E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of hist...
TMPJ-01304	C1QTNF1 Protein, Human, Recombinant (His) C1QTNF1,G Protein-Coupled Recepto...	Human	HEK293 Cells
	C1QTNF1 is a secreted protein，contains 1 C1q domain and 1 collagen-like domain. C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a C-terminal globular domain. C1qTNF proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms. C1QTNF1 is a novel adipokine, providing a significant framew...
TMPJ-01214	ZNF100 Protein, Human, Recombinant (His) Zinc Finger Protein 100,ZNF100	Human	E. coli
	Zinc Finger Protein 100 (ZNF100) is part of the krueppel C2H2-type zinc-finger protein family. ZNF100 contains 12 C2H2-type zinc fingers and 1 KRAB domain. ZNF100 is a DNA-binding protein domain consisting of zinc fingers. Zinc finger protein 100 occurs in nature as the part of transcription factors conferring DNA sequence specificity as the DNA-binding domain. Zinc finger proteins have also found use in protein engineering due to their modularity and have prospects as components of tools for us...
TMPH-01266	RNF13 Protein, Human, Recombinant (His) RING finger protein 13,E3 ubiquitin-protein ligase ...	Human	E. coli
	RNF13 Protein, Human, Recombinant (His) is expressed in E. coli with N-terminal 10xHis tag. The predicted molecular weight is 26.2 kDa. Accession number: O43567
TMPH-02050	RNF114 Protein, Human, Recombinant (GST) Zinc finger protein 313,RING finger protein 1	Human	E. coli
	RNF114 Protein, Human, Recombinant (GST) is expressed in E. coli.

重组蛋白

Neurofibromin/NF1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01756

Species: Human

Expression System: E. coli

RNF13 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01267

Species: Human

Expression System: E. coli

C1QTNF1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01304

Species: Human

Expression System: HEK293 Cells

ZNF100 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01214

Species: Human

Expression System: E. coli

RNF13 Protein, Human, Recombinant (His)

Cat.No: TMPH-01266

Species: Human

Expression System: E. coli

RNF114 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02050

Species: Human

Expression System: E. coli

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