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Targets Recommended: Melanocortin Receptor

1

抑制剂 & 化合物

1

天然产物

9

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Cat. No. Product Name Target Signaling Pathways
T5464 JNJ-10229570

JNJ10229570,UNII-N9IX402L35,JNJ 10229570

Melanocortin Receptor GPCR/G Protein; Neuroscience
JNJ-10229570 (UNII-N9IX402L35) 是肾上腺皮质受体 1 和肾上腺皮质受体 5 的拮抗剂,可抑制皮脂腺分化和皮质特异性脂质的产生,其抑制125I-NDP-α-MSH 和人类细胞中 MC1R 和 MC5R 结合的IC50值分别为 270 nM 和 200 nM。

化合物

JNJ-10229570
Cat.No: T5464
Synonym: JNJ10229570,UNII-N9IX402L35,JNJ 10229570
Target: Melanocortin Receptor
Cat. No. Product Name Target Signaling Pathways
T19268 D-Sedoheptulose 7-phosphate

Others Others
D-Sedoheptulose 7-phosphate is a common precursor of heptaic acid (group III) and hygromycin B (group IV) heptasaccharide. D-heptadecane 7-phosphate can be converted to NDP-heptose by similar biosynthetic pathways in these compounds.

天然产物

D-Sedoheptulose 7-phosphate
Cat.No: T19268
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-01782 Norrin Protein, Human, Recombinant (GST & His & Myc)

Norrie disease protein,NDP,X-linked exudative vitre...

Human E. coli
Norrin Protein, Human, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular weight is 47.6 kDa and the accession number is Q00604.
TMPH-03452 NDPK Protein, S. cerevisiae, Recombinant (His)

Nucleoside diphosphate kinase,YNK1

Saccharomyces cerevisiae P. pastoris (Yeast)
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.2 kDa and the accession number is P36010.
TMPH-03451 NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)

YNK1,Nucleoside diphosphate kinase

Saccharomyces cerevisiae E. coli
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.2 kDa and the accession number is P36010.
TMPY-01773 CNDP2 Protein, Human, Recombinant (His)

CNDP dipeptidase 2 (metallopeptidase M20 family),CP...

Human Baculovirus Insect Cells
CNDP2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.2 kDa and the accession number is CAC69883.1.
TMPY-02733 CNDP1 Protein, Mouse, Recombinant (His)

AI746433,carnosine dipeptidase 1 (metallopeptidase M20 famil...

Mouse HEK293 Cells
CNDP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.5 kDa and the accession number is Q8BUG2.
TMPY-00719 CNDP1 Protein, Human, Recombinant (His)

HsT2308,CN1,carnosine dipeptidase 1 (metallopeptidase M20 fa...

Human HEK293 Cells
CNDP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.3 kDa and the accession number is Q96KN2.
TMPY-01739 CNDP2 Protein, Mouse, Recombinant (His)

C76600,Dip-2,Pep-1,Cn2,0610010E05Rik,Pep1,CNDP dipe...

Mouse Baculovirus Insect Cells
CNDP2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.22 kDa and the accession number is Q9D1A2.
TMPH-01199 CNDP2 Protein, Human, Recombinant (E. coli, His)

HEL-S-13,CPGL,Threonyl dipeptidase,PEPA,CNDP dipept...

Human E. coli
CNDP2 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-00099 NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

Nucleoside diphosphate kinase 1,NDK1,Nucleoside diphosphate ...

Arabidopsis thaliana P. pastoris (Yeast)
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a role in response to reactive oxygen species (ROS) stress. NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 20.5 kDa and the accession number is P39207.

重组蛋白

Norrin Protein, Human, Recombinant (GST & His & Myc)
Cat.No: TMPH-01782
Species: Human
Expression System: E. coli
NDPK Protein, S. cerevisiae, Recombinant (His)
Cat.No: TMPH-03452
Species: Saccharomyces cerevisiae
Expression System: P. pastoris (Yeast)
NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)
Cat.No: TMPH-03451
Species: Saccharomyces cerevisiae
Expression System: E. coli
CNDP2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01773
Species: Human
Expression System: Baculovirus Insect Cells
CNDP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02733
Species: Mouse
Expression System: HEK293 Cells
CNDP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00719
Species: Human
Expression System: HEK293 Cells
CNDP2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01739
Species: Mouse
Expression System: Baculovirus Insect Cells
CNDP2 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01199
Species: Human
Expression System: E. coli
NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
Cat.No: TMPH-00099
Species: Arabidopsis thaliana
Expression System: P. pastoris (Yeast)
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