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Search Results for " nci-c-04671 "

Targets Recommended: Apoptosis Dehydrogenase DNA/RNA Synthesis Antifolate ADC Cytotoxin

4

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T1485	Methotrexate NCI-C04671,WR19039,Amethopterin,甲氨蝶呤,CL14377	Apoptosis; Dehydrogenase; DNA/RNA Synthesis; Antifolate; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Methotrexate (WR19039) 是一种叶酸类似物，一种二氢叶酸还原酶 DHFR 的抑制剂。Methotrexate 具有抗代谢、抗肿瘤和免疫抑制等活性，常用于类风湿关节炎和多种肿瘤的研究。
T65289	Methotrexate (hydrate)	Others	Others
	Methotrexate (hydrate) 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65289，CAS号为 133073-73-1。
T28027	Methotrexate monohydrate Methotrexate hydrate	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	Methotrexate monohydrate is a DHhF reductase inhibitor. Methotrexate monohydrate increases T cell apoptosis, decreases T cell activation and suppresses cytokine production.
T29965	Amethopterin DL-Amethopterin	Others	Others
	Amethopterin is a chemotherapy drug and immune system inhibitor used to treat cancers of the blood, bone, lung, breast, head, and neck. In addition, it can treat rheumatoid arthritis and psoriasis.

化合物

Cat.No: T1485

Synonym: NCI-C04671,WR19039,Amethopterin,甲氨蝶呤,CL14377

Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate, ADC Cytotoxin

Methotrexate (hydrate)

Cat.No: T65289

Target: Others

Methotrexate monohydrate

Cat.No: T28027

Synonym: Methotrexate hydrate

Target: Others, ADC Cytotoxin

Cat.No: T29965

Synonym: DL-Amethopterin

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01450	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi) KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01451	HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi) NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC,KI-RAS,KRAS,...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

重组蛋白

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01450

Species: Human

Expression System: HEK293 Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01456

Species: Human

Expression System: HEK293 Cells

HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01451

Species: Human

Expression System: HEK293 Cells

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