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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T16713 R121919

NBI30775

Others Others
R121919 (NBI30775) 是一种高效的促肾上腺皮质激素释放因子受体 1 (CRF1)小分子受体拮抗剂,具有抗抑郁和抗焦虑活性,抑制 CRF1 受体、 CRF2 受体和 CRF 结合蛋白。
T38228 R 121919 hydrochloride

Others Others
High affinity corticotropin releasing factor receptor1 (CRF1) antagonist (Ki = 3.5 nM). Reduces stress-induced elevations of plasma ACTH. Anxiolytic and antidepressant in vivo. Orally bioavailable. Chen and Grigoriadis (2005) NBI 30775 (R121919), an orally active antagonist of the corticotropin-releasing factor (CRF) type-1 receptor for the treatment of anxiety and depression. Drug Dev.Res. 65 216 |Jutkiewicz et al (2005) The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919...

化合物

R121919
Cat.No: T16713
Synonym: NBI30775
Target: Others
R 121919 hydrochloride
Cat.No: T38228
Synonym:
Target: Others
TargetMol Loading
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