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Cat. No. | Product Name | ||
---|---|---|---|
L2200 | 酪氨酸激酶分子库 | 1016 compounds | |
1016 种酪氨酸激酶抑制剂的独特集合,可用于高通量筛选和高内涵筛选; | |||
L1600 | 激酶抑制剂库 | 2720 compounds | |
2720 种激酶抑制剂/调节剂的独特集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L1610 | FDA 上市激酶抑制剂库 | 263 compounds | |
263种靶向激酶的上市药物集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7856 |
Naphthol AS-E
色酚 AS-E,nAS-E |
Epigenetic Reader Domain; Histone Acetyltransferase | Chromatin/Epigenetic |
Naphthol AS-E (nAS-E) 是一种具有细胞渗透性的KIX-KID 相互作用的抑制剂,可用于癌症研究。它直接结合 CBP 的 KIX 域,Kd 为 8.6 µM,阻断 KIX 域和 KID 域的相互作用,IC50为 2.26 µM。 | |||
T69959 |
NAS-181 free base
|
Others | Others |
NAS-181 free base is a 5-HT(1B) receptor antagonist. | |||
T23055 |
NAS181
NAS-181 |
Others | Others |
rat 5-HT1B receptor antagonist | |||
T62585 |
NAS-181
|
Others | Others |
NAS-181 是一种选择性大鼠 5-羟色胺 1B (r5-HT1B) 的有效拮抗剂 (Ki: 47 nM)。NAS-181 可以加强大鼠脑区 5-HTP 的积累。 | |||
T0889 |
Saccharin
O-Sulfobenzimide,O-Benzoic sulfimide,Saccharimide,Benzoic sulfimide,糖精 |
Others; Antibacterial | Microbiology/Virology; Others |
Saccharin (O-Sulfobenzimide) 是一种口服有效的人造甜味剂,具有抑菌和微生物调节特性。 | |||
T69958 |
Tofacitinib maleate
|
Others | Others |
Tofacitinib maleate, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib maleate modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs. JAK enzymes transmit cytokine signaling through pairing of JAKs (e.g., JAK1/JAK3, JAK1/JAK2, JAK1/TyK2, JAK2/JAK2). Tofacitinib maleate inhibited the in vitro activities of JAK1/JAK2, JAK1/JAK3, and JAK2/JAK2 combinations with IC50 of 406, 56, and 1377 nM, respectively. | |||
T78362 |
Transglutaminase
TG |
||
Transglutaminase (TG) 是一种硫醇酶,促使蛋白质分子间交联,通过催化谷氨酰胺残基的γ-羧酰胺基团与其他化合物的一级ε-胺基团形成异肽键。该酶在包括凝血、抗菌免疫反应和光合作用在内的多种生理过程中发挥作用。 | |||
T9268 |
Ulinastatin
|
Others | Others |
Ulinastatin 是一种多价 Kunitz 型丝氨酸蛋白酶抑制剂,具有抗炎特性。 | |||
T83627 |
Pim-1 kinase inhibitor 8
|
Pim; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling |
Pim-1 kinase inhibitor 8 是一种高效的 Pim-1 kinase 抑制剂,具有抗癌活性,可有效抑制细胞迁移。Pim-1 kinase inhibitor 8 对 MCF-7 和 HepG2 细胞有细胞毒性,是研究乳腺癌的候选化合物。 | |||
T74671 |
ROS kinases-IN-2
|
ROS Kinase | Tyrosine Kinase/Adaptors |
ROS kinases-IN-2 是一种有效的 ROS kinase 抑制剂,在 10 μM 时测得抑制率为 21.53%。ROS kinases-IN-2 具有潜在的抗癌活性,可用于研究异常细胞生长。 | |||
T9315 |
mTOR kinase Inhibitor 2
|
Others | Others |
2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]- 是有效的mTOR 抑制剂,对于mTOR 和PI3Kα的IC50分别为0.176 μM 和 >30 μM。 | |||
T77648 |
Casein kinase 1δ-IN-14
WAY-637081 |
Others | Others |
Casein kinase 1δ-IN-14(WAY-637081) 可用于研究动脉粥样硬化相关心血管疾病。 | |||
T67755 |
Protein kinase G inhibitor-1
|
PKA | Tyrosine Kinase/Adaptors |
Protein kinase G inhibitor-1是有效的蛋白激酶G 抑制剂,IC50= 0.9 uM。 | |||
T60220 |
ROS kinases-IN-1
|
ROS Kinase | Tyrosine Kinase/Adaptors |
ROS kinases-IN-1 是一种 ROS 酪氨酸激酶抑制剂,IC50 值为 1.22 μM。ROS kinases-IN-1 具有抗肿瘤活性。 | |||
T12721 |
Rho-Kinase-IN-1
|
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
Rho-Kinase-IN-1 是一种 ROCK 抑制剂,对 ROCK1 和 ROCK2 的 Kis 分别为 30.5 nM 和 3.9 nM。 Rho-Kinase-IN-1 可用于细胞过度增殖、重塑、水肿和炎症疾病的研究。 | |||
T15654 |
Ketohexokinase inhibitor 1
PF-06835919 |
Others | Others |
Ketohexokinase inhibitor 1 是一种酮己糖激酶抑制剂(对 KHK-C 和 KHK-A 的 IC50:分别为 8.4 nM 和 66 nM)。 | |||
T12728 |
RIP2 Kinase Inhibitor 3
|
Others; RIP kinase | Apoptosis; NF-κB; Others |
RIP2 Kinase Inhibitor 3 是一种有效的选择性 受体相互作用蛋白2 激酶抑制剂,IC50 为 1 nM。 | |||
T6409 |
ALK kinase inhibitor-1
SAR348830 |
Others | Others |
SAR348830 是间变性淋巴瘤激酶ALK 抑制剂。 | |||
T67944 |
p38 MAP Kinase Inhibitor Ⅵ
|
p38 MAPK | MAPK |
p38 MAP Kinase Inhibitor Ⅵ是一种有效的p38 MAP Kinase 抑制剂,具有抗炎活性。 | |||
T4048 |
Monastrol
(±)-Monastrol |
Apoptosis; Kinesin | Apoptosis; Cytoskeletal Signaling |
Monastrol ((±)-Monastrol) 是一种具有高效性和细胞渗透性的有丝分裂驱动蛋白Eg5的抑制剂,IC50值为 14 μM。 | |||
T5466 |
Tyrosine kinase-IN-1
|
VEGFR; FGFR; FLT; PDGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Tyrosine kinase-IN-1是一种多靶点酪氨酸激酶抑制剂,能够抑制KDR (IC50:4 nM),Flt-1 (IC50:20 nM),FGFR1 (IC50:4 nM) 和 PDGFRα (IC50:2 nM)。 | |||
T2346 |
Enasidenib
恩西地平,AG-221 |
Dehydrogenase; Isocitrate Dehydrogenase (IDH) | Metabolism |
Enasidenib (AG-221) 是口服具有活力的、可逆的、选择性IDH2突变酶抑制剂,抑制IDH2R140Q 和 IDH2R172K 的IC50分别为100 和 400 nM。 | |||
T16987 |
TAO Kinase inhibitor 1
|
Others; MAPK | MAPK; Others |
TAO Kinase inhibitor 1 是一种ATP 竞争性的thousand-and-one amino acid kinases (TAOK)选择性抑制剂,对于 TAOK1 和 TAOK2 的IC50s 分别为 11 nM 和 15 nM。它能够延迟有丝分裂以及诱导有丝分裂细胞死亡。 | |||
T60278 |
Tyrosinase-IN-2
|
Tyrosinase | Proteases/Proteasome |
Tyrosinase-IN-2 (compound 67) 是一种有效的酪氨酸酶抑制剂。酪氨酸酶是一种含铜金属酶,负责黑色素生物合成和酶促褐变中的限速催化步骤。Tyrosinase-IN-2 具有研究皮肤美白剂和食品防腐剂的潜力。 | |||
T37385 |
Glutaminase-IN-3
|
Glutaminase | Proteases/Proteasome |
Glutaminase-IN-3 是一种有效的的 Glutaminase 1 抑制剂,具有潜在的抗肿瘤活性,对 GLS1 具有抑制作用,可用于研究癌症。 | |||
T76177 |
Endo-1,3-β-glucanase
Lyticase |
Endogenous Metabolite | Metabolism |
Endo-1,3-β-glucanase (Lyticase) 是一种来自真菌和扇贝法氏衣原体的葡聚糖酶,在真菌细胞上显示出裂解活性。Endo-1,3-β-glucanase 可沿β-葡聚糖链随机切割β-1-3糖苷键。 | |||
T6797 |
Telaglenastat
CB 839,CB839,CB-839 |
transporter; Glutaminase; Autophagy | Autophagy; Metabolism; Proteases/Proteasome |
Telaglenastat (CB 839) 是一种谷氨酰胺酶 1 (GLS1) 抑制剂,具有选择性、可逆性和口服活性。Telaglenastat 具有抗肿瘤活性,可以诱导细胞自噬。 | |||
T67939 |
Tyrosinase-IN-16
|
Others | Others |
Tyrosinase-IN-16对酪氨酸酶具有抑制作用。 | |||
T79860 |
TIE-2/VEGFR-2 kinase-IN-5
|
VEGFR; Tie-2 | Angiogenesis; Tyrosine Kinase/Adaptors |
TIE-2/VEGFR-2 kinase-IN-5 是一种高效的 TIE-2 和 VEGFR-2 酪氨酸激酶受体抑制剂,具有的抗血管生成活性,常用于血管生成相关的生物医学研究领域。 | |||
T62560 |
Sirpiglenastat
DRP-104 |
Glutaminase | Proteases/Proteasome |
Sirpiglenastat (DRP-104) 是一种谷氨酰胺 (glutamine) 拮抗剂,是DON的前药,具有抗肿瘤活性,通过抑制谷氨酰胺代谢和刺激先天性和适应性免疫系统来发挥作用。 | |||
T50072 |
FLT3 kinase inhibitor 2HCl
|
Others | Others |
3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride 用于多种化合物的合成。 | |||
T77501 |
TAO Kinase inhibitor 2
|
Serine/threonin kinase | Cell Cycle/Checkpoint; Metabolism |
TAO Kinase inhibitor 2 是 TAO 激酶 抑制剂 ,IC50为50-500 nM。TAO Kinase inhibitor 2 对 KIAA1361 和 JIK 具有抑制作用,IC50s 为 50-500 nM。 | |||
T3118 |
Dimethylenastron
|
Kinesin | Cytoskeletal Signaling |
Dimethylenastron 是一种驱动蛋白Eg5抑制剂,IC50值为 200 nM。它可阻止具有单极纺锤体的细胞,所有染色体都以单极纺锤体方式附着在该纺锤体上。 | |||
T4191 |
Multi-kinase inhibitor 1
Multi-kinase inhibitor I |
Others; Bcr-Abl; PDGFR; c-Kit | Angiogenesis; Cytoskeletal Signaling; Others; Tyrosine Kinase/Adaptors |
Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) 是多激酶抑制剂。它有用于导致与酪氨酸激酶活性异常或失控有关的疾病或失调的潜力,特别是与c-Kit,PDGF-R,Bcr-abl 活性相关的疾病。 | |||
T2129 |
Zaprinast
|
PDE | Metabolism |
Zaprinast 是一种 cGMP 选择性的磷酸二酯酶(PDE)抑制剂,是一种 GPR35激动剂,对大鼠 GPR35 有很强的激活作用,对人 GPR35 有一定的激活作用。它通过抗增殖和促凋亡作用,减少血管的重构。 | |||
T10276 |
AKT Kinase Inhibitor
|
Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
AKT Kinase Inhibitor 是一种具有抗肿瘤活性的 Akt 抑制剂,以剂量依赖的方式选择性抑制细胞增殖。 | |||
T10687 |
Casein Kinase II Inhibitor IV
|
Casein Kinase | Metabolism; Stem Cells |
Casein Kinase II Inhibitor IV 是一种小分子诱导剂,可诱导表皮角质形成细胞分化。 | |||
T73616 |
Glutamate dehydrogenase (NAD(P))
GLDH |
Mitochondrial Metabolism | Metabolism |
Glutamate dehydrogenase NAD(P) (GLDH)是一种线粒体酶,广泛存在于生物体内,催化谷氨酸可逆的氧化脱氨生成 α-酮戊二酸 (α-KG),可用于研究谷氨酸代谢异常引起的疾病。 | |||
T10276L |
AKT Kinase Inhibitor HCl
AKT Kinase Inhibitor HCl(842148-40-7 Free base) |
Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
AKT Kinase Inhibitor HCl 是一种 Akt 抑制剂,具有抗肿瘤活性。 | |||
T6335 |
Tie2 kinase inhibitor 1
Tie2 kinase inhibitor |
Tie-2 | Tyrosine Kinase/Adaptors |
Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor) 是Tie2激酶选择性抑制剂9IC50:250 nM),具有抗癌作用。 | |||
T12187L |
Naspm trihydrochloride
1-Naphthylacetyl spermine trihydrochloride |
iGluR | Membrane transporter/Ion channel; Neuroscience |
Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride) 是Joro 蜘蛛毒素的合成类似物,具有拮抗CP-AMPA 受体的活性。 | |||
T8864 |
Thymidylate Kinase Inhibitor, YMU1
|
Others | Others |
YMU1 是一种选择性抑制剂,特异性作用于人胸苷酸激酶 (IC50: 610 nM) 。 | |||
T1848 |
Dynasore
Dynamin Inhibitor I |
Dynamin; Virus Protease; Autophagy; HSV | Autophagy; Cytoskeletal Signaling; Microbiology/Virology |
Dynasore (Dynamin Inhibitor I) 是一种可渗透细胞的化学物质,可逆且非竞争性地抑制 dynamin 1/2 的 GTPase 活性。 它还抑制线粒体动力蛋白 Drp1,对其他小 GTPase 没有影响。 | |||
T0488 |
Finasteride
非那雄胺,MK-906 |
Reductase | Endocrinology/Hormones; Metabolism |
Finasteride (MK-906) 是 5α-还原酶的竞争性抑制剂,对 II 型 5α-还原酶的IC50为 4.2 nM,对 II 型 5α-还原酶的亲和力是 I 型酶的 100 倍。它可用于研究前列腺增生和雄激素性脱发。 | |||
T6488 |
Epinastine hydrochloride
Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat |
5-HT Receptor; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Epinastine hydrochloride (WAL-801CL HCl) 是抗组胺剂和肥大细胞稳定剂,是一种可口服的选择性组胺 H1 受体拮抗剂,可抑制 IL-8 释放,具有抗过敏作用。 | |||
T22831 |
Protein kinase inhibitor H-7 dihydrochloride
H-7 dihydrochloride |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride0) 是一种有效的蛋白激酶 C(PKC)抑制剂。Protein kinase inhibitor H-7 dihydrochloride(100 μM)显著抑制 TPA (皮肤肿瘤启动子,12-O-tetradecanoylphorbol-13-acetate) 和磷脂酶 C 促使的 ODC (鸟氨酸脱羧酶),抑制 PMA 诱导的混杂细胞溶解活性。 | |||
T64376 |
Casein kinase 1δ-IN-9
|
NADPH | Metabolism |
Casein kinase 1δ-IN-9是一种醌还原酶2(Quinone reductase 2)抑制剂,IC50为0.6μM。 | |||
T31792 |
Filaminast
UNII-CDD69JC61J,Way-pda-641,WAY-PDA 641,CDD69JC61J |
PDE | Metabolism |
Filaminast (UNII-CDD69JC61J) 是磷酸二酯酶4抑制剂(PDE4抑制剂)和罗利普兰的类似物,罗利普兰被用作抗哮喘药物。 | |||
T9940 |
Protein kinase G inhibitor-2
|
Others | Others |
Protein kinase G inhibitor-2 具有抗菌、抗病毒和抗肿瘤活性。 | |||
T9564 |
IRE1α kinase-IN-1
|
IRE1 | Cell Cycle/Checkpoint |
IRE1α kinase-IN-1 是IRE1α 的选择性抑制剂(IC50为 77 nM),对 IRE1α 的选择性高于 IRE1β 亚型 100 倍。它抑制内质网诱导的 IRE1α 寡聚和自磷酸化,并抑制 IRE1α RNase 活性 (IC50=80 nM)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T41044 |
Naringinase
|
Glucosidase | Metabolism |
Naringinase 是一种在自然界中广泛存在的水解酶复合物,具有 α-L-鼠李糖苷酶和 β-D-葡萄糖苷酶的活性,主要用于糖苷的水解。 | |||
TQ0036 |
Anemarrhenasaponin I
|
Others | Others |
Anemarrhenasaponin I 是一种对血小板聚集有显著的抑制作用的传统中药。 | |||
TN1377 |
α-Spinasterol
Α-波菜甾醇,alpha-Spinasterol,菠甾醇 |
COX; Antibacterial; TRP/TRPV Channel | Immunology/Inflammation; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience |
α-Spinasterol 是一种从Spinacia oleracea 分离的瞬时受体电位香草酸 1 拮抗剂,具有抗菌、抗炎、抗抑郁、抗氧化和抗伤害作用。它抑制COX-1和COX-2活性,IC50值分别为 16.17 μM 和 7.76 μM。 | |||
T21205 |
Ponasterone A
坡那甾酮A,AI3-44686 |
Others | Others |
Ponasterone A 是一种蜕皮激素,能够高度亲和蜕皮激素受体。它能够使报告基因能够快速打开和关闭,是细胞和转基因动物中基因表达的有效调节剂。 | |||
TN6931 |
Anemarrhenasaponin Ia
知母皂苷IA |
Others | Others |
Anemarrhenasaponin Ia ((2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5R,6R)-4,5-dihydroxy-2-{[(1R,3R,4R,7S,9S,12S,13S,16S,18R)-3-hydroxy-6-methoxy-7,9,13-trimethyl-6-(3-methylbutyl)-5-oxapentacyclo[10.8.0.02,?.0?,?.013,1?]icosan-16-yl]oxy}-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxan) 具有抗炎活性。Anemarrhenasaponin Ia 具有抗炎作用,从知母根茎中分离得到。 Anemarrhenasaponin Ia 抑制 N-甲酰-甲硫氨酰-亮氨酰-苯丙氨酸 (fMLP) 诱导的超氧化物的进一步产生。 | |||
T64812 |
Collagenase Type I
Collagenase I,Collagenase Type I (From microorganisms) |
Others | Others |
Collagenase Type I 是一种蛋白水解酶,能分解胶原蛋白中的肽键(胶原蛋白是结缔组织的主要结构蛋白)。Collagenase 已被探索作为一种潜在的治疗选择来分解突出的椎间盘物质,从而减少对附近神经的压迫。Collagenase 可能有助于过度疤痕组织的分解和重组,潜在地改善组织功能和外观。Collagenase 具有治疗椎间盘突出、瘢痕疙瘩、脂肪团、脂肪瘤以及佩罗尼氏病和手掌纤维瘤病等方面的潜力。 | |||
T13827 |
Pronase E (Activity ≥ 7000 U/g)
Pronase,Pronase E |
Others | Others |
Pronase E 是一种蛋白水解酶混合物,从灰色链霉菌 (Streptomyces griseus) 中获得,能够将蛋白质消化成单个氨基酸。 | |||
T19529 |
Proteinase
|
Others | Others |
Proteinase 是一种催化蛋白质分解的酶。它们通过水解作用来裂解蛋白质内的肽键,将蛋白质分解成更小的多肽或单个氨基酸。Proteinase 参与许多生物功能,包括消化进食的蛋白质、旧蛋白质的分解,以及细胞信号传递。它们同时促进新的蛋白质产物的形成 | |||
T3667 |
Kalii Dehydrographolidi Succinas
Ddhads,穿琥宁,Dehydroandrographolide Succinate Potasium Salt |
Others | Others |
Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) 从中药穿心莲中提取得到,具有免疫刺激、抗感染和抗炎作用,对病毒性肺炎和病毒性上呼吸道感染具有潜在的研究价值。 | |||
TN4489 | Manassantin A | ERK; cAMP; TNF; NF-κB; MAPK; COX; HIF; Prostaglandin Receptor; JNK; STAT | Angiogenesis; Apoptosis; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Stem Cells |
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibition of iNOS production and NF-κB act | |||
TN5766 |
Nandinaside A
|
||
Nandinaside A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5766,CAS号为 1813517-23-5。 | |||
TN3814 |
Delta 5-avenasterol
|
Others | Others |
Delta 5-avenasterol has antioxidant activity. | |||
TN1382 |
Anemarrhenasaponin III
|
Others | Others |
Anemarrhenasaponin III is a natural product | |||
T75574 |
Monascorubramine
|
Others | Others |
Monascorubramine,一种由Talaromyces属的红曲素 (Monascus) 产生的微生物着色剂,在不同pH值条件下表现出不同的色调和色度值。 | |||
T75476 |
Monaschromone
|
Others | Others |
Monaschromone 是一种聚酮代谢物,可显著抑制灰霉病菌、茄病菌、稻瘟病菌和索比内蒂菌的生长,MIC 值在 6.25 至 12.5 μM 之间。 | |||
T82533 |
Donasine
|
||
Donasine是一种退热效果的吲哚生物碱天然产物,可从芦竹根茎中提取。 | |||
T12093 |
Monascin
|
Others | Others |
Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice),exhibits anti-tumor-initiating activity and anti-inflammatory activity . | |||
T82300 |
Gluconasturtiin
|
||
Gluconasturtiin 作为P. maculipennis幼虫的摄食诱导剂,但其高浓度会对幼虫产生毒害效应。 | |||
T31371 |
Nasunin
Violanin,Delphanin |
Others | Others |
Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels. | |||
TMA1799 | alpha-Spinasterol glucoside | Others | Others |
alpha-Spinasterol glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TMA1799,CAS号为 1745-36-4。 | |||
TN3815 |
Delta 7-avenasterol
|
||
Delta 7-avenasterol has antioxidant activity. | |||
TN4490 | Manassantin B | ERK; BCL; p38 MAPK; TNF; NF-κB; JNK; STAT; Antifection | Apoptosis; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells |
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in pa... | |||
TN3391 |
alpha-Spinasterol acetate
|
Others | Others |
alpha-Spinasterol has a significant therapeutic potential to modulate the development and/or progression of diabetic nephropathy. | |||
TN2038 |
Panasenoside
|
Others | Others |
Panasenoside is a natural product | |||
T81116 |
Spinasaponin E
|
||
Spinasaponin E 是一种具有研究潜力的化合物,适用于探索炎性疾病的治疗机制。 | |||
T11150 |
Ecteinascidin 770
Ecteinascidine 770,Et-770 |
Others | Others |
Ecteinascidin 770 (ET-770) inhibits U373MG cells and is a 1,2,3, 4-tetrahydroisoquinoline alkaloid with strong anticancer activity.IC50 is 4.83 nM. | |||
T75684 |
Monascorubrin
|
Others | Others |
Monascorubrin 是一种从红曲菌菌丝体中纯化获得的化合物,对枯草芽孢杆菌和拟假丝酵母显示出显著的抗生素活性。 | |||
T11364 |
Ganoderic acid TR
|
Antiviral; Influenza Virus | Immunology/Inflammation; Microbiology/Virology |
Ganoderic acid TR 是一种从药用灵芝中分离出口来的三萜化合物,是 H5N1 和 H1N1 NAs 抑制剂,具有广谱的抗病毒活性。 | |||
TN4105 | Ganoderic acid T-Q | Others | Others |
Ganoderic acid T-Q and TR are two inhibitors of H5N1 and H1N1 NAs. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00904 |
Urokinase/uPA Protein, Human, Recombinant (His)
u-PA,QPD,BDPLT5,ATF,UPA,plasminogen activator, urokinas<... |
Human | HEK293 Cells |
Urokinase/uPA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is A0A024QZM9. | |||
TMPK-01392 |
Tenascin Protein, Human, Recombinant (His)
Tenascin-C,TNC,TN,Hexabrachion,Hxb,TN-C |
Human | HEK293 Cells |
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors. Tena... | |||
TMPY-01355 |
Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)
G-α-h,HEL-S-45,TGC,transglutaminase 2,TG2,GNAH,G-AL... |
Human | Baculovirus Insect Cells |
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. It is a calcium-dependent acyltransferase that also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. TGM2 is a multi-functional protein which... | |||
TMPY-02585 |
Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His)
aSMase,ASM,Zn-SMase,A-SMase,sphingomyelin phosphodiesterase ... |
Mouse | Baculovirus Insect Cells |
Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) in length as the pro form, while Isoform 2 and isoform 3 have lost catalytic activity. The active SMPD1 isoform 1 contains one saposin B-type domain that likely interacts with sphingomyelin, and a catalytic region. Human SMPD1 is 86% aa identical to mouse SMPD1. SMPD1 is a monome... | |||
TMPY-03855 |
DNase I Protein, Human, Recombinant (His)
DRNI,DNL1,deoxyribonuclease I |
Human | HEK293 Cells |
DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. DNaseI binds to the cytoskeletal protein actin. It binds actin monomers with very high (sub-nanomolar) affinity and actin polymers with lower affinity. Mutations i... | |||
TMPK-01393 |
Tenascin Protein, Mouse, Recombinant (His)
Hexabrachion,Hxb,TN-C,TN,TNC,Tenascin-C |
Mouse | HEK293 Cells |
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors. Tena... | |||
TMPY-04412 |
Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST)
mitogen-activated protein kinase kinase ki... |
Human | Baculovirus Insect Cells |
Mitogen-activated protein kinase kinase kinase kinase 2, also known as B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, Rab8-interacting protein, and MAP4K2, is cytoplasm and peripheral membrane protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE2 subfamily. MAP4K2 contains one CNH domain and one protein kinase domain. Although this kinase is found in many tissues, its express... | |||
TMPY-04394 |
Glucokinase Protein, Human, Recombinant
glucokinase (hexokinase 4),HXKP,MODY2,FGQT... |
Human | E. coli |
Glucokinase belongs to the bacterial glucokinase family. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but ... | |||
TMPY-04480 |
UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His)
CMPK,UMPK,UMK,CK,UMP-CMPK,CMK,cytidine monophosphate (UMP-CM... |
Human | Baculovirus Insect Cells |
CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid bi... | |||
TMPY-02769 |
RNASET2 Protein, Human, Recombinant (His)
bA514O12.3,RP11-514O12.3,RNASE6PL,ribonuclease T2 |
Human | Baculovirus Insect Cells |
RNASET2 (ribonuclease T2) is an enzyme that belongs to the RNase T2 family. It is highly expressed in the temporal lobe and fetal brain. RNASET2 gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. Defects in RNASET2 are the cause of leukoencephalopathy cystic without megalencephaly. An infantile-onset syndrome of cerebral leukoencephalopathy.... | |||
TMPY-04385 |
ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST)
death-associated protein kinase 3,DLK,ZIP,ZIPK |
Human | Baculovirus Insect Cells |
Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP kinase subfamily. DAPK3 / ZIPK contains oneprotein kinase domain. It is a serine/threonine kinase which acts as a positive regulator of apoptosis. It phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. DAPK3 / ZIPK is a homodimer or forms heterodimers with AT... | |||
TMPH-00123 |
Endoglucanase D Protein, Aspergillus kawachii, Recombinant (His & SUMOstar)
eglD,cel61A,AA9 family lytic polysaccharide monooxygenas... |
Aspergillus kawachii | P. pastoris (Yeast) |
Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates. Endoglucanase D Protein, Aspergillus kawachii, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 55.7 kDa and the accession number is Q96WQ9. | |||
TMPH-03738 |
Endochitinase B Protein, Zea mays, Recombinant (His & Myc)
ChitB,CHIB,Endochitinase B,Seed chitinase ... |
Zea mays | E. coli |
Defense against chitin-containing fungal pathogens. | |||
TMPH-00603 |
Cytidylate kinase Protein, E. coli, Recombinant (His & SUMO)
Cytidine monophosphate kinase,CMP kinase,y... |
E. coli | E. coli |
ATP, dATP, and GTP are equally effective as phosphate donors. CMP and dCMP are the best phosphate acceptors. | |||
TMPH-03489 |
SARS-CoV-2 3C-like proteinase NSP5 Protein (His)
|
SARS-CoV-2 | E. coli |
SARS-CoV-2 3C-like proteinase NSP5 Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 39.8 kDa and the accession number is YP_009725301.1. | |||
TMPH-00607 |
Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO)
CD,Cytosine deaminase,CDase,CDA,codA,Cytosine amino... |
E. coli | E. coli |
Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.5 kDa and the accession number is P25524. | |||
TMPH-03164 |
Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
Beta-lactamase OXA-10,bla,Beta-lactamase PSE-2,oxa10,pse2 |
Pseudomonas aeruginosa | E. coli |
Hydrolyzes both carbenicillin and oxacillin. Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.5 kDa and the accession number is P14489. | |||
TMPH-02270 |
Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO)
SK29-AB,LB24-AB,TYR,Monophenol monooxygenase,Tyrosi... |
Human | E. coli |
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. | |||
TMPH-00693 |
L-lactate dehydrogenase Protein, E. coli O9:H4, Recombinant (His)
lldD,L-lactate dehydrogenase |
E. coli | E. coli |
Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain. | |||
TMPH-03155 |
Lys-gingipain HG66 Protein, Porphyromonas gingivalis, Recombinant (His & Myc)
Lys-gingipain HG66,kgp |
Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. Lys-gingipain HG66 Protein, Porphyromonas gingivalis, Recombinant (His & Myc) is expressed in E.... | |||
TMPH-00467 |
Hydroxylysine kinase Protein, Danio rerio, Recombinant (His & Myc & SUMO)
hykk,Hydroxylysine kinase |
Danio rerio (Zebrafish) | E. coli |
Hydroxylysine kinase Protein, Danio rerio, Recombinant (His & Myc & SUMO) is expressed in E. coli. | |||
TMPH-03584 |
Shikimate dehydrogenase Protein, S. epidermidis, Recombinant (His & Myc)
Shikimate dehydrogenase (NADP(+)),aroE |
Staphylococcus epidermidis | E. coli |
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). It can also use NAD to oxidize shikimate. Shikimate dehydrogenase Protein, S. epidermidis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.4 kDa and the accession number is Q5HNV1. | |||
TMPH-03187 |
PHT3 Protein, Pseudomonas putida, Recombinant (His & Myc)
pht3,Phthalate 4,5-dioxygenase oxygenase s... |
Pseudomonas putida | E. coli |
N/A. PHT3 Protein, Pseudomonas putida, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 56.7 kDa and the accession number is Q05183. | |||
TMPH-03154 |
Lys-gingipain 381 Protein, Porphyromonas gingivalis, Recombinant (His)
kgp,Lys-gingipain 381 |
Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. Lys-gingipain 381 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli e... | |||
TMPH-03177 |
RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)
Elastase modulator,rhlR,Regulatory protein RhlR,HTH-type quo... |
Pseudomonas aeruginosa | E. coli |
Necessary for transcriptional activation of the rhlAB genes encoding the rhamnosyltransferase. It also functions as a transcriptional activator of elastase structural gene (lasB). Binds to autoinducer molecules BHL (N-butanoyl-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone). RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 47.6 kDa and the accession n... | |||
TMPH-00163 |
Levanase Protein, Bacillus sp., Recombinant (His & SUMO)
2,6-beta-D-fructan fructanohydrolase,Endo-levanase,... |
Bacillus | E. coli |
Catalyzes the hydrolysis of levan with endo-type specificity. The products of levan hydrolysis are a mixture of fructose and a series of fructooligosaccharides up to 12-mer, with levantriose being the major oligosaccharide obtained. Is not active towards sucrose. Levanase Protein, Bacillus sp., Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.3 kDa and the accession number is O31411. | |||
TMPY-06666 |
Fra a 1 Protein, Fragaria Ananassa, Recombinant
|
Fragaria Ananassa | P. pastoris (Yeast) |
Fra a 1 Protein, Fragaria Ananassa, Recombinant is expressed in P. pastoris yeast expression system. The predicted molecular weight is 27.5 kDa. | |||
TMPY-04432 |
Sphingosine Kinase 1/SPHK1 Protein, Human, Recombinant
SPHK,SPHK1,sphingosine kinase 1,SPK |
Human | Baculovirus Insect Cells |
Sphingosine Kinase 1/SPHK1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.7 kDa and the accession number is Q9NYA1-1. | |||
TMPJ-01147 |
Cld Protein, Dechloromonas aromatica, Recombinant (His)
Daro_2580,Chlorite O(2)-lyase,Chlorite dismutase,Cld |
Dechloromonas aromatica | E. coli |
Chlorite dismutase (Cld) found in prokaryotic organisms, also known as Chlorite O2-lyase, is a b-type heme containing enzyme that catalyzes the reduction of chlorite into chloride plus dioxygen. The subunit of chlorite dismutase consists of a heme free N-terminal and a heme b containing C-terminal ferredoxin-like fold with high structural homology to the dye-decolorizing peroxidases (DyPs). The physiological role of Cld in prokaryote has been shown that some microorganisms can use perchlorate or... | |||
TMPH-00031 |
Aerolysin Protein, Aeromonas sobria, Recombinant (His & Myc)
Hemolysin |
Aeromonas sobria | E. coli |
Secreted, cytolytic toxin that forms pores in host membranes after proteolytic removal of a C-terminal propeptide, leading to destruction of the membrane permeability barrier and cell death. The pores are formed by transmembrane beta-strands and are approximately 3 nm in diameter. | |||
TMPH-00847 |
2-5A-dependent Rnase Protein, Human, Recombinant (Myc)
Ribonuclease L,RNASEL,Ribonuclease 4,2-5A-dependent... |
Human | E. coli |
2-5A-dependent Rnase Protein, Human, Recombinant (Myc) is expressed in E. coli expression system with C-Myc tag. The predicted molecular weight is 85.1 kDa and the accession number is Q05823. | |||
TMPH-03185 |
4-OT Protein, Pseudomonas putida, Recombinant (His)
tdnL,4-oxalocrotonate tautomerase,2-hydroxymuconate tautomer... |
Pseudomonas putida | E. coli |
Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate. 4-OT Protein, Pseudomonas putida, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 10.9 kDa and the accession number is Q93JW0. | |||
TMPH-00135 |
Endochitinase Protein, Avena sativa, Recombinant (His)
|
Avena sativa | E. coli |
This protein functions as a defense against chitin-containing fungal pathogens. Endochitinase Protein, Avena sativa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.7 kDa and the accession number is P86181. | |||
TMPH-03166 |
Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
PAE,lasB,Pseudolysin,Neutral metalloproteinase,Elas... |
Pseudomonas aeruginosa | E. coli |
Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase. Autocatalyses processing of its pro-peptide. Processes the pro-peptide of pro-chitin-binding protein (cbpD). Involved in the pathogenesis of P.aeruginosa infections. Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.1 kDa and the accession number is P14756. | |||
TMPH-03165 |
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
Beta-lactamase,ampC,ampA,Cephalosporinase |
Pseudomonas aeruginosa | E. coli |
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.7 kDa and the accession number is P24735. | |||
TMPH-03503 |
Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO)
ATP-AMP transphosphorylase,AK,Adenylate monophosphate ki... |
Shigella flexneri | E. coli |
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 43.6 kDa and the accession number is Q83M40. | |||
TMPH-00576 |
Agmatinase Protein, E. coli, Recombinant (His & SUMO)
Agmatine ureohydrolase,AUH |
E. coli | E. coli |
Catalyzes the formation of putrescine from agmatine. Agmatinase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.5 kDa and the accession number is B7LFJ6. | |||
TMPH-00168 |
Levanase Protein, Bacillus subtilis, Recombinant (His)
sacC,Exo-beta-D-fructosidase,Beta-D-fructofuranosidase,Leva<... |
Bacillus subtilis | E. coli |
Exo-fructosidase that can hydrolyze both levan and inulin, leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose, but not melezitose, stachylose, cellobiose, maltose, and lactose. Levanase Protein, Bacillus subtilis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 77.2 kDa and the accession number is P05656. | |||
TMPH-00713 |
Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc)
Polyphosphoric acid kinase,ATP-polyphosphate phosph... |
E. coli | E. coli |
Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 87.7 kDa and the accession number is P0A7B1. | |||
TMPH-03179 |
LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)
UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetyla... |
Pseudomonas aeruginosa | E. coli |
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 53.4 kDa and the accession number is A6VB79. | |||
TMPH-03136 |
L-lactate dehydrogenase Protein, Plasmodium berghei, Recombinant (His & Myc)
LDH,L-lactate dehydrogenase |
Plasmodium berghei | E. coli |
N/A. L-lactate dehydrogenase Protein, Plasmodium berghei, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.4 kDa and the accession number is Q7SI97. | |||
TMPH-03178 |
TusA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
tusA,Sulfur carrier protein TusA |
Pseudomonas aeruginosa | E. coli |
Sulfur carrier protein which probably makes part of a sulfur-relay system. TusA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 21.8 kDa and the accession number is Q9I3F3. | |||
TMPH-03151 |
Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (His)
Gingipain 1,Gingipain R1,RGP-1,Arg-gingipain,rgpA |
Porphyromonas gingivalis | P. pastoris (Yeast) |
Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable). Gingipain R1 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 56.0 kDa and the accession number is P28784. | |||
TMPH-03580 |
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc)
Staphylococcus aureus neutral proteinase,aur,Zinc m... |
Staphylococcus aureus | E. coli |
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.2 kDa and the accession number is P81177. | |||
TMPH-01459 |
Human herpesvirus 7 (HHV-7) (strain JI) Probable ganciclovir kinase (His & Myc)
Probable ganciclovir kinase,U69 |
HHV-7 | E. coli |
Human herpesvirus 7 (HHV-7) (strain JI) Probable ganciclovir kinase (His & Myc) is expressed in E. coli. | |||
TMPH-01779 |
RNASE2 Protein, Human, Recombinant (His)
Ribonuclease US,Eosinophil-derived neurotoxin,Non-secretory ... |
Human | E. coli |
This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. RNASE2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.5 kDa and the accession number is P10153. | |||
TMPH-03167 |
toxR Protein, Pseudomonas aeruginosa, Recombinant (His)
toxR,Exotoxin A regulatory protein |
Pseudomonas aeruginosa | E. coli |
Positive regulation of toxA gene transcription. toxR Protein, Pseudomonas aeruginosa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.9 kDa and the accession number is P09852. | |||
TMPY-02418 |
kynureninase/KYNU Protein, Mouse, Recombinant (His)
kynureninase,4432411A05Rik |
Mouse | Baculovirus Insect Cells |
kynureninase/KYNU Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.7 kDa and the accession number is Q9CXF0. | |||
TMPY-02413 |
Isocitrate dehydrogenase/IDH1 Protein, Human, Recombinant (His)
HEL-S-26,HEL-216,IDP,IDCD,PICD,IDH,isocitrate dehydrogen... |
Human | E. coli |
Isocitrate dehydrogenase/IDH1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 48 kDa and the accession number is O75874. | |||
TMPY-04685 |
Arginase 1/ARG1 Protein, Human, Recombinant (His & MYC)
arginase 1,ARG1 |
Human | HEK293 Cells |
Arginase 1/ARG1 Protein, Human, Recombinant (His & MYC) is expressed in HEK293 mammalian cells with His and MYC tag. The predicted molecular weight is 36.7 kDa and the accession number is P05089-1. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMIJ-0225 |
Finasteride-d9
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Finasteride-d9 是 Finasteride 的氘代化合物。Finasteride 的 CAS 号为 98319-26-7。Finasteride 是 5α-还原酶的竞争性抑制剂,对 II 型 5α-还原酶的IC50为 4.2 nM,对 II 型 5α-还原酶的亲和力是 I 型酶的 100 倍。它可用于研究前列腺增生和雄激素性脱发。 |