17
7
69
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16409 |
OSMI-1
|
Others; Acyltransferase | Metabolism; Others |
OSMI-1 是一种 O-GlcNAc 转移酶 (OGT) 抑制剂 (IC50=2.7 μM),具有口服活性和细胞渗透性。OSMI-1 可以抑制蛋白质 O-GlcNA 酰化,而不会定性地改变细胞表面 N- 或 O- 连接的聚糖。 | |||
T3161L |
BACE-IN-1 acetate
BACE-IN-1 acetate (350228-37-4,Free base) |
BACE | Neuroscience |
BACE-IN-1 acetate (BACE-IN-1 acetate (350228-37-4,Free base)) 已被用作 BACE1 抑制剂测定中的 β 位淀粉样前体蛋白 (APP) 裂解酶-1 (BACE1) 抑制剂。 β-位点淀粉样前体蛋白 (APP) 切割酶-1 (BACE1)是一种天冬氨酸蛋白酶,属于蛋白酶家族,由六个腔内半胱氨酸残基组成。这些残基有助于形成三个分子间二硫键和 N-连接的糖基化位点。 | |||
T25968 |
PMPA sodium
PMPA sodium salt,PMPA tetrasodium salt,PMPA Na |
Others | Others |
PMPA sodium is a potent and selective glutamate carboxypeptidase 2 (GCP II/N-acetylated a-linked dipeptidase/NAALADase) inhibitor. | |||
T29499 |
A 601
A601,A-601 |
Others | Others |
A 601 is a lipid A analog derived from N-acylated serine-linked nonphosphorylated acylglucosamine. | |||
T12326 |
OSMI-2
|
Others | Others |
OSMI-2 is a cell-permeable inhibitor of O-linked N-acetylglucosamine transferase (OGT). | |||
T63988 |
(Rac)-OSMI-1
|
Others | Others |
(Rac)-OSMI-1 是 OSMI-1 的外消旋体。其中 OSMI-1 是 O-GlcNAc 转移酶 (OGT) 抑制剂 (IC50: 2.7 μM)。OSMI-1 对哺乳动物细胞系中的蛋白 O-连接的 N-乙酰氨基葡萄糖 (O-GlcNAcylation) 具有抑制作用,且不会定性地改变细胞表面 N-或 O-连接的聚糖。 | |||
T76153 |
PNGase F
|
Others | Others |
PNGase F 是一种糖苷酶,可催化寡糖中内部糖苷键的裂解。PNGase F 可从糖蛋白中去除几乎所有的 N-连接寡糖。 | |||
T75412 |
Peptide-N-Glycosidase F (PNGaseF)
|
Others | Others |
Peptide-N-Glycosidase F (PNGaseF) 是一种天冬酰胺酰胺酶。Peptide-N-Glycosidase F 催化来自糖蛋白的高甘露糖、杂合和复杂寡糖的内层 GlcNAc 和天冬酰胺残基之间的 N-连接寡糖裂解。Peptide-N-Glycosidase F 可用于糖蛋白的结构和功能研究。 | |||
T74549 |
N-Acetyl-α-D-glucosamine 1-phosphate disodium
|
Others | Others |
N-acetyl-α-d-glucosamine 1-phosphate disodium (GlcNAc-1-P) 为异位糖磷酸盐,关键中间体于N-糖蛋白生物合成。该化合物同时作为细菌细胞壁组分磷胆酸和鼠胺的代谢前体。 | |||
T37530 |
Glycerophospho-N-Arachidonoyl Ethanolamine
|
Others | Others |
N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. The different types of NAE can be derived from glycerophospho-linked precursors by the activity of glycerophosphodiesterase 1 (GDE1). Glycerophospho-N-arachidonoyl ethanolamine is the precursor of arachidonoyl ethanolamide (AEA), also known as anandamide. AEA is an endogenous cannabinoid neurotransmitter that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. It inhibit... | |||
T37850 |
Chitobiose Octaacetate
|
Others | Others |
Chitobiose is a dimer of β-1,4 linked glucosamine units derived from chitin, which, in turn, is a long chain polymer of N-acetylglucosamine that is a primary component of fungal cell walls and arthropod exoskeletons. Chitobiose octaacetate is a form of chitobiose containing eight acetate groups. It is formed by the acetolysis of chitin. Chitobiose octaacetate can be used for the synthesis of chitobiose oxazoline and other chitin precursors. | |||
T38049 |
Glycerophospho-N-Palmitoyl Ethanolamine
|
Others | Others |
N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. For example, arachidonoyl ethanolamide (AEA) is an endogenous neurotransmitter that evokes cellular responses by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). The different types of NAE are derived from glycerophospho-linked precursors by the activity of glycerophosphodiesterase 1 (GDE1). Glycerophospho-N-palmitoyl ethanolamine (GP-NPEA) is the metabo... | |||
T36577 |
K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt)
K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt) |
Others | Others |
Histone H2B (108-125) is a peptide fragment of histone H2B that corresponds to amino acid residues 109-126 of the human histone H2B sequence. It contains an N-terminal biotinylated lysine followed by a tryptophan linker. Histone H2B can be modified by addition of an O-linked N-acetylglucosamine (GlcNAc) moiety to the serine residue at position 112, which promotes monoubiquitination of the lysine at position 120.1 Both of these modifications are associated with active transcription. Histone H2B a... | |||
T37347 |
6'-Sialyllactose Sodium Salt
6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose |
Others | Others |
6'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 6 position. This connection is at the 3 position in the related compound, 3’-sialyllactose. Both are major milk oligosaccharides that avidly bind several viral strains, including strains of influenza, HIV-1, reovirus, and polyomavirus.[1],[2],[3],[4],[5],[6] These compounds can be used to differentiate and characterize the binding domains of viruses that recognize N-acetylne... | |||
TP2260 |
Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens]
|
Others | Others |
Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens] is a fragment (Gly-Val-Ala-Leu-His-Arg-Pro-Asp-Val-Tyr-Leu-Leu-Pro-Pro-Ala-Arg) on the human immunoglobulin micro heavy chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cell | |||
T38292 |
4-(N-Boc-amino)piperidine
|
Others | Others |
4-(N-Boc-amino)piperidine is an organic building block.1,2It has been used in the synthesis of aminopiperidine antiviral chemokine (C-C motif) receptor 5 (CCR5) antagonists and antibacterial agents. 1.Burrows, J.N., Cumming, J.G., Fillery, S.M., et al.Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3,3-diphenylpropyl)-piperidinyl amides and ureasBioorg. Med. Chem. Lett.15(1)25-28(2005) 2.Reck, F., Alm, R., Brassil, P., et al.Novel N-linked aminopiperidine inhibitor... | |||
T83898 |
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine
SFN-Cys,D,L-Sulforaphane-L-cysteine |
Others | Others |
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SFN-Cys) 是一种异硫氰酸酯衍生物及第一类和第二类组蛋白去乙酰化酶(HDAC)抑制剂和抗癌剂硫代硫酸烯醇醚的活性代谢产物。它通过巯基乙酸途径酶从硫代硫酸烯醇醚经DL-硫代硫酸烯醇醚谷胱甘肽和硫代硫酸烯醇醚半胱氨酸甘肽中间体形成。SFN-Cys (20 µM) 通过创伤愈合和腔室分析实验,分别减少了U87MG和U373 MG胶质母细胞瘤细胞的侵袭和迁移。在45 µM的浓度下,它降低了对紫杉醇耐药的A549肺癌细胞(A549/T)中的α-微管蛋白、βIII-微管蛋白、司他敏1和X连锁抑制剂的凋亡(XIAP)的水平,并减少了细胞密度。使用30 µM浓度的SFN-Cys诱导U87MG和U373 MG细胞凋亡和G2/M期细胞周期停滞。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13229 |
Tunicamycin
|
Influenza Virus; Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Tunicamycin 是一种抗生素的混合物,通过阻断 GlcNAc 磷酸转移酶 (GPT),抑制 N-连接糖基化。Tunicamycin 具有抗肿瘤活性,还具有抗细菌、抗真菌和抗病毒活性。 | |||
T22468 |
1-Deoxymannojirimycin hydrochloride
|
Others; Influenza Virus; HIV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
1-Deoxymannojirimycin hydrochloride 是一种选择性的 α1,2-甘露糖苷酶抑制剂,IC50值为 20 μM。它还抑制 HIV-1 毒株,抗病毒活性较差。 | |||
T1715 |
Chitosan (MW 150000)
壳聚糖,Chitosan,Poly(D-glucosamine),Deacetylated chitin |
Antibacterial; Antifungal | Microbiology/Virology |
Chitosan (MW 150000) (Deacetylated chitin) 是衍生自几丁质的聚阳离子线性多糖。它无毒,具有低致敏性,生物相容性和可生物降解性。它还具有抗肿瘤,抗细菌,抗真菌和抗氧化活性。 | |||
T2S1008 |
Oxysophoridine
Sophoridine N-oxide,氧化槐定碱 |
Apoptosis; Antioxidant | Apoptosis; oxidation-reduction |
Oxysophoridine (Sophoridine N-oxide) 是从苦豆子中提取的一种生物碱,具有抗发炎,抗氧化应激和抗凋亡的作用。 | |||
T8053 |
N-Acetyl-L-arginine
N-Α-乙酰-L-精氨酸,Ac-Arg-OH |
Endogenous Metabolite | Metabolism |
N-Acetyl-L-arginine (Ac-Arg-OH) 是一种胍基诺化合物,被发现存在于血液渗析性肾不足儿童患者血清中的。 | |||
T40436 |
N,N'-Diacetylchitobiose
|
Others | Others |
N,N'-Diacetylchitobiose, a dimer of β(1,4) linked N-acetyl-D glucosamine, is derived from the hydrolysis of chitin. This compound serves as an alternative carbon source for E. coli. | |||
T37219 |
N-Palmitoyl Glycine
|
Others | Others |
The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolamide (AEA; anandamide). N-palmitoyl glycine (PalGly) contains an 18-carbon saturated fatty acid that is amide-linked to glycine and is structurally similar to the phospholipid-derived N-acyl ethanolamines. Endogenously produced in rat skin and spinal cord, PalGly is present in 100... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00009 |
OGT Protein, Human, Recombinant (His & SUMO)
OGT,O-GlcNAc transferase subunit ... |
Human | E. coli |
OGT Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 62.5 kDa and the accession number is O15294. | |||
TMPY-02668 |
NAALADL1 Protein, Mouse, Recombinant (His)
N-acetylated alpha-linked acidic dipeptida... |
Mouse | HEK293 Cells |
NAALADL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80 kDa and the accession number is Q7M758. | |||
TMPY-01215 |
NAALADL1 Protein, Human, Recombinant (His)
N-acetylated alpha-linked acidic dipeptida... |
Human | HEK293 Cells |
NAALADL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80 kDa and the accession number is Q9UQQ1-1. | |||
TMPH-01527 |
NAALADL2 Protein, Human, Recombinant (His)
Inactive N-acetylated-alpha-linke... |
Human | E. coli |
May be catalytically inactive. | |||
TMPJ-01251 |
POMGNT1 Protein, Human, Recombinant (His)
2-N-Acetylglucosaminyltransferase... |
Human | HEK293 Cells |
Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystr... | |||
TMPY-00828 |
Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
MPS2,IDS,SIDS,iduronate 2-sulfatase |
Human | HEK293 Cells |
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, an... | |||
TMPH-03198 |
MGAT1 Protein, Rabbit, Recombinant (His & Myc)
MGAT1,Alpha-1,3-mannosyl-glycoprotein<... |
Rabbit | E. coli |
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. MGAT1 Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.2 kDa and the accession number is P27115. | |||
TMPH-02117 |
SPRR3 Protein, Human, Recombinant (His & SUMO)
Cornifin beta,Esophagin,SPRR3,Sma... |
Human | E. coli |
Cross-linked envelope protein of keratinocytes. SPRR3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 34.0 kDa and the accession number is Q9UBC9. | |||
TMPH-00130 |
Mannosyl-oligosaccharide alpha-1,2-mannosidase 1B Protein, Aspergillus phoenicis, Recombinant (His & Myc)
mns1B,Class I alpha-mannosidase 1... |
Aspergillus phoenicis | E. coli |
Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). Mannosyl-oligosaccharide alpha-1,2-mannosidase 1B Protein, Aspergillus phoenicis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 61.3 kDa and the accession number is Q12563. | |||
TMPH-02936 |
FUCA1 Protein, Mouse, Recombinant (His & SUMO)
Alpha-L-fucosidase I,Alpha-L-fucoside fucohydrolase 1,Tissue... |
Mouse | E. coli |
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. FUCA1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 66.6 kDa and the accession number is Q99LJ1. | |||
TMPH-02287 |
ZRANB1 Protein, Human, Recombinant (His & Myc)
TRAF-binding domain-cont... |
Human | E. coli |
Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling. ZRANB1 Prot... | |||
TMPH-02116 |
SPRR2B Protein, Human, Recombinant (His & Myc)
Small proline-rich protein 2B,SPRR2B |
Human | P. pastoris (Yeast) |
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. SPRR2B Protein, Human, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 12.0 kDa and the accession number is P35325. | |||
TMPH-03435 |
MNT3 Protein, S. cerevisiae, Recombinant (E. coli, His)
Alpha-1,3-mannosyltransferase M |
Saccharomyces cerevisiae | E. coli |
Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans. MNT3 Protein, S. cerevisiae, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 74.7 kDa and the accession number is P40549. | |||
TMPH-01615 |
OPN1LW Protein, Human, Recombinant (His)
Red cone photoreceptor pigment,Lon |
Human | E. coli |
Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. OPN1LW Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.4 kDa and the accession number is P04000. | |||
TMPH-01868 |
FUCA2 Protein, Human, Recombinant (GST)
Plasma alpha-L-fucosidase,FUCA2,Alpha-L-fucoside fucohydrola... |
Human | E. coli |
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. FUCA2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 77.7 kDa and the accession number is Q9BTY2. | |||
TMPH-02909 |
Sprr2a1 Protein, Mouse, Recombinant (His)
small proline-rich protein 2A,Small proli<... |
Mouse | E. coli |
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Sprr2a1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 13.4 kDa and the accession number is Q9CQK8. | |||
TMPH-00074 |
GlcNAcT-I Protein, Arabidopsis thaliana, Recombinant (His)
N-acetylglucosaminyltransferase I... |
Arabidopsis thaliana | Baculovirus Insect Cells |
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. Required for normal root growth and morphology. GlcNAcT-I Protein, Arabidopsis thaliana, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 51.6 kDa and the accession number is Q9XGM8. | |||
TMPY-01856 |
MGAT5 Protein, Human, Recombinant (His)
mannosyl (alpha-1,6-)-glycoprotein |
Human | HEK293 Cells |
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, also known as Alpha-mannoside beta-1,6-N-acetylglucosaminyl-transferase, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferase V, MGAT5, and GGNT5, is a single-pass type II membrane protein that belongs to the glycosyltransferase 18 family. MGAT5 / GGNT5 catalyzes the addition of N-acetylglucosamine in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of t... | |||
TMPH-03436 |
MNT3 Protein, S. cerevisiae, Recombinant (His)
Alpha-1,3-mannosyltransferase M |
Saccharomyces cerevisiae | Baculovirus Insect Cells |
Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans. MNT3 Protein, S. cerevisiae, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 71.2 kDa and the accession number is P40549. | |||
TMPY-03810 |
GALNT2 Protein, Human, Recombinant (His)
GalNAc-T2,polypeptide N-acetylgalactosami<... |
Human | HEK293 Cells |
GALNT2, also known as GalNAc-T2, is a member of the GalNAc-transferases family. Members of this family transfer an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. GALNT2 may play a role in lipid metabolism. It catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GALNT2 has a broa... | |||
TMPH-00701 |
PBP1b Protein, E. coli, Recombinant (His & Myc)
Penicillin-binding prote... |
E. coli | E. coli |
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). PBP1b Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.6 kDa and the accession number is P02919... | |||
TMPH-03044 |
PBP1a Protein, MenB, Recombinant (His & SUMO)
mrcA,Penicillin-binding ... |
MenB | E. coli |
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). | |||
TMPH-01696 |
SLC16A4 Protein, Human, Recombinant (His)
SLC16A4,Monocarboxylate transporter 5,Solu... |
Human | E. coli |
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. SLC16A4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 17.7 kDa and the accession number is O15374. | |||
TMPY-03972 |
Aspartylglucosaminidase/AGA Protein, Human, Recombinant (His)
GA,AGU,ASRG,aspartylglucosaminidase |
Human | HEK293 Cells |
AGA (Aspartylglucosaminidase) is an amidohydrolase enzyme involved in the catabolism of N-linked oligosaccharides of glycoproteins. This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. Diseases associated with AGA include Aspartylglucosaminuria and Lysosomal Storage Disease. An important paralog of this gene is ASRGL1. | |||
TMPH-01059 |
Cathepsin B Protein, Human, Recombinant (GST)
Cathepsin B1,APPS,Cathepsin B,CPSB,APP sec... |
Human | E. coli |
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis. Cathepsin B Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.6 kDa and the accession number is P07858. | |||
TMPJ-00686 |
B4GALT3 Protein, Human, Recombinant (His)
β-1,4-galactosyltransferase 3,Beta-1,B4GALT3 |
Human | HEK293 Cells |
Beta-1,4-galactosyltransferase 3 (B4GALT3) belongs to the glycosyltransferase 7 family. It is responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. It is highest expression in placenta, prostate, testis, ovary, intestine and muscle, and in fetal brain. | |||
TMPH-02539 |
MGAT3 Protein, Mouse, Recombinant (His & Myc)
Mgat3,Beta-1,4-mannosyl-glycoprotein |
Mouse | E. coli |
It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains, called bisecting N-acetylglucosamine (GlcNAc). It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. The addition of this bisecting GlcNAc residue alters not only the composition,... | |||
TMPJ-01223 |
GALNTL1 Protein, Human, Recombinant (His)
UDP-GalNAc:Polypeptide N-,Polypeptide Gal<... |
Human | HEK293 Cells |
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1, also known as Polypeptide GalNAc transferase-like protein 1, Protein-UDP acetylgalactosaminyltransferase-like protein 1, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1, GalNAC-T-like protein 1, pp-GaNTase-like protein 1 and GALNTL1, belongs to the glycosyltransferase 2 family. GALNTL1 plays an important role in the protein modification and protein glycosylation process. GALNTL1 uses the manganese and ... | |||
TMPH-00170 |
PBP 4 Protein, Bacillus subtilis, Recombinant (His & SUMO)
pbpD,Penicillin-binding ... |
Bacillus subtilis | E. coli |
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (Probable). Has a partially redundant function with PBP-2A (pbpA) during spore outgrowth. PBP 4 Protein, Bacillus subtilis, Recombinant (His & SUMO) is expressed in E. coli expression system with N... | |||
TMPJ-00687 |
B4GALT4 Protein, Human, Recombinant (His)
UDP-Gal:β-GlcNAc β-1,β4Gal-T4,4-Galactosyltran<... |
Human | HEK293 Cells |
β-1,4-galactosyltransferase 4 (B4GALT4) is a single-pass type II membrane protein that belongs to the Glycosyltransferase 7 family. B4GALT4 consist of the following 2 domains: N-Acetyllactosamine Synthase and β-N-Acetylglucosaminyl-Glycolipid β-1,4-Galactosyltransferase. B4GALT4 is highly expressed in the heart, placenta, kidney, and pancreas; it is lowly expressed in the brain, colon, lung, muscle, ovary, testis, and uterus. B4GALT4 function is responsible for the synthesis of complex-type N-li... | |||
TMPH-03536 |
FabI Protein, S. aureus, Recombinant (His & SUMO)
Enoyl-[acyl-carrier-protein] reductase [ |
Staphylococcus aureus | E. coli |
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism. FabI Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.0 kDa and the accession number is Q6GI75. | |||
TMPH-03584 |
Shikimate dehydrogenase Protein, S. epidermidis, Recombinant (His & Myc)
Shikimate dehydrogenase (NADP(+)),aroE |
Staphylococcus epidermidis | E. coli |
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). It can also use NAD to oxidize shikimate. Shikimate dehydrogenase Protein, S. epidermidis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.4 kDa and the accession number is Q5HNV1. | |||
TMPY-02480 |
Chymotrypsin C Protein, Human, Recombinant (His)
ELA4,CLCR,chymotrypsin C (caldecrin) |
Human | HEK293 Cells |
Chymotrypsin C (abbreviated for CTRC), also known as caldecrin or elastase4, is a digestive enzyme of the peptidase S1 family. This enzyme is synthesized as an inactivate chymotrypsinogen. On cleavage by trypsin into two parts that activate each other by removing two small peptides in a trans-proteolysis, chymotrypsin C produced. N-linked glycosylation of human CTRC is required for efficient folding and secretion, however, the N-linked glycan is unimportant for enzyme activity or inhibitor bindi... | |||
TMPJ-00724 |
LDHA Protein, Human, Recombinant (His)
LDH-M,Renal Carcinoma Antigen... |
Human | E. coli |
L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria. | |||
TMPK-00043 |
IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-21,白介素,Interleukin-21,白细胞介素,CVID11,Za11 |
Human | E. coli |
Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cytokines. It has been implicated in many immunological processes and has been linked to autoimmune diseases, allergies and other inflammatory diseases. IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 18.30 kDa and the accession number... | |||
TMPK-01172 |
IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated
白介素,Interleukin-21,IL-21,Za11,CVID11,白细胞介素 |
Mouse | E. coli |
Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cytokines. It has been implicated in many immunological processes and has been linked to autoimmune diseases, allergies and other inflammatory diseases. IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 17.9 kDa and the accession number ... | |||
TMPK-00729 |
Siglec-6 Protein, Human, Recombinant (His & Avi)
SIGLEC6,OBBP1,CD327,CD33L1,CD33 antigen-li... |
Human | HEK293 Cells |
Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains.Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. | |||
TMPH-01265 |
PELI3 Protein, Human, Recombinant (His)
PELI3,E3 ubiquitin-protein ligase pelli |
Human | E. coli |
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation. PELI3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.8 kDa and the access... | |||
TMPJ-00330 |
GPC1 Protein, Human, Recombinant (His)
Glypican-1,GPC1 |
Human | HEK293 Cells |
The Glypicans are a small multigene family of GPI-linked proteoglycans that play a key role in growth factor signaling. Human Glypican 1 (GPC1) is synthesized as a 558 amino acid (aa) preproprecursor that contains a 23 aa signal sequence, a 507 aa mature segment, and a 28 aa C-terminal prosegment. There are two potential N-linked and four potential O-linked sites for glycosylation or glycanation. There are potentially two heparan sulfate (HS) modifications on GPC1 that could contribute to a nati... | |||
TMPY-02430 |
BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx)
BCL5,ZNF51,B-cell CLL/lymphoma 6,LAZ3,ZBTB27,BCL6A |
Human | E. coli |
The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon... | |||
TMPJ-01350 |
XPNPEP3 Protein, Human, Recombinant (His)
XPNPEP3,X-Pro Aminopeptidase 3,Amin |
Human | E. coli |
Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-s... | |||
TMPY-02718 |
Doublecortin/DCX Protein, Human, Recombinant (aa 45-150, GST)
XLIS,doublecortin,LISX,DBCN,DC,SCLH |
Human | E. coli |
DCX (doublecortin, N-GST chimera)contains 2 doublecortin domains and belongs to the doublecortin family. It is highly expressed in neuronal cells of fetal brain, but not expressed in other fetal tissues. In the adult, it is highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas. DCX is a microtubule-associated protein required for initial steps of neuronal dispersion an... | |||
TMPJ-00565 |
Mucin-15/MUC15 Protein, Human, Recombinant (His)
MUC15,Mucin-15,MUC-15 |
Human | HEK293 Cells |
Mucin-15 is a single-pass type I membrane protein member of the Mucin family. Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most metazoans. A key characteristic of Mucins is their ability to form gels. Therefore they are a key component in most gel-like secretions, serving functions from lubrication to cell signalling to forming chemical barriers. Mucin-15 is expressed in many tissues. Mucin-15 is highly glycosylat... | |||
TMPJ-00923 |
Calnexin Protein, Human, Recombinant (His)
p90,Calnexin,CANX,Major Histocomp... |
Human | HEK293 Cells |
Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may ... | |||
TMPJ-01397 |
Siglec-7 Protein,Human,Recombinant(aa 19-353, His)
AIRM1,p75/AIRM1,CD328 antigen,CD328,AIRM-1... |
Human | HEK293 Cells |
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Eleven human Siglecs have been cloned and characterized. Human Siglec-7 encodes a 467 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N-terminal Ig-like V-type domain, two Ig-like C2-type domains, a transmembrane region ... | |||
TMPY-02300 |
BIN1 Protein, Human, Recombinant (His)
AMPHL,bridging integrator 1,AMPH2,SH3P9 |
Human | E. coli |
Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicated in rare and common diseases affecting different tissues and physiological functions. BIN1 downregulation is linked to cancer progression and also correlates with ventricular cardiomyopathy and arrhythmia preceding heart failure. Increased BIN1 expression is linked to increased... | |||
TMPJ-00060 |
IL-25/IL17E Protein, Human, Recombinant (His)
白细胞介素,IL17E,白介素,IL-17E,IL-25,IL25,Interleukin |
Human | HEK293 Cells |
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a non-covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are pro-inflammator... | |||
TMPH-00813 |
Hepatitis E virus genotype 1 (HEV-1) Secreted protein ORF2 (His)
Protein ORF2,Pro-secreted protein ORF2 |
HEV-1 | Baculovirus Insect Cells |
Plays a role in the inhibition of host antibody-mediated neutralization without blocking viral cell entry.; Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter. The capsid is composed of 60 copies linked to each other. Binds to the 5' end of the genomic RNA to mediate genome encapsidation. Binds to heparin surface proteoglycans (HSPGs) to mediate viral entry. Additionally, the interactions with host ASGR1 and ASGR2 facilitate viral infection of hepatocytes. Hepatitis E virus gen... | |||
TMPJ-01254 |
Siglec-F Protein, Mouse, Recombinant (His)
sialic acid binding Ig like lectin |
Mouse | HEK293 Cells |
Siglec 5 to 11 share a high degree of sequence similarity with CD33/Siglec-3 both in their extracellular and intracellular regions. They are collectively referred to as CD33-related Siglecs. One remarkable feature of the CD33-related Siglecs is their differential expression pattern within the hematopoietic system. This fact, together with the presence of two conserved immunoreceptor tyrosine-based inhibition motifs (ITIMs) in their cytoplasmic tails, suggests that CD33-related Siglecs are involv... | |||
TMPY-04270 |
GPR133 Protein, Human, Recombinant (His)
PGR25,GPR133 |
Human | HEK293 Cells |
ADGRD1 (Adhesion G Protein-Coupled Receptor D1, also known as GPR133) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. ADGRD1, an orphan member of the adhesion family of G-protein-coupled receptors, is a critical regulator of the response to hypoxia and tumor growth in Glioblastoma (GBM). ADGRD1 represents a novel molecular target in GBM and possibly other malignancies where hypoxia is fundamental to pathogenesis. Variations in the ADGRD1 locus are linked with... | |||
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