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Search Results for " myosin light chain kinase, smooth muscle "

Targets Recommended: Serine/threonin kinase Myosin YAP PKA PKC

4

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T3050	ML-7 hydrochloride ML-7 HCl,ML-7盐酸盐	Serine/threonin kinase; Myosin; YAP; PKA; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors
	ML-7 hydrochloride (ML-7 HCl) 是一种可渗透细胞的、可逆的、有效的、ATP 竞争性的肌球蛋白轻链激酶(MLCK) 特异性抑制剂，IC50为300 nM。它还抑制平滑肌肌球蛋白轻链激酶、PKA 和 PKC。
T1433	Ritodrine hydrochloride DU21220,盐酸利托君,Ritodrine HCl,NSC 291565	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Ritodrine hydrochloride (NSC 291565) 是一种 β-2肾上腺素受体激动剂。
T16145	MS-444 BE-34776	Others	Others
	MS-444 suppresses the activity of purified smooth muscle myosin light chain kinase (MLCK) (IC50: 10 μM).
TP1710	Calmodulin Binding Peptide 1
	Calmodulin Binding Peptide 1, a potent CaM-binding peptide with picomolar (pM) affinity, originates from smooth muscle myosin light-chain kinase (MLCK peptide). It effectively blocks inositol trisphosphate (IP3)-induced calcium (Ca2+) release [1].

化合物

ML-7 hydrochloride

Cat.No: T3050

Synonym: ML-7 HCl,ML-7盐酸盐

Target: Serine/threonin kinase, Myosin, YAP, PKA, PKC

Ritodrine hydrochloride

Cat.No: T1433

Synonym: DU21220,盐酸利托君,Ritodrine HCl,NSC 291565

Target: Adrenergic Receptor

Cat.No: T16145

Synonym: BE-34776

Target: Others

Calmodulin Binding Peptide 1

Cat.No: TP1710

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00379	MLCK Protein, Chicken, Recombinant (His & Myc & SUMO) Mylk,Telokin,Myosin light chain <...	Chicken	E. coli
	Phosphorylates a specific serine in the N-terminus of a myosin light chain, which leads to the formation of calmodulin/MLCK signal transduction complexes which allow selective transduction of calcium signals. MLCK Protein, Chicken, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 52.9 kDa and the accession number is P11799.
TMPH-03753	MYLK Protein, Human, Recombinant (His) MYLK,Myosin light chain kinas...	Human	E. coli
	Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscl...
TMPY-04385	ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST) death-associated protein kinase 3,DLK,ZIP,ZIPK	Human	Baculovirus Insect Cells
	Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP kinase subfamily. DAPK3 / ZIPK contains oneprotein kinase domain. It is a serine/threonine kinase which acts as a positive regulator of apoptosis. It phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. DAPK3 / ZIPK is a homodimer or forms heterodimers with AT...

重组蛋白

MLCK Protein, Chicken, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-00379

Species: Chicken

Expression System: E. coli

MYLK Protein, Human, Recombinant (His)

Cat.No: TMPH-03753

Species: Human

Expression System: E. coli

ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04385

Species: Human

Expression System: Baculovirus Insect Cells

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