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Search Results for " monomethyl dolastatin-10 "

Targets Recommended: Microtubule Associated ADC Cytotoxin

抑制剂 & 化合物

重组蛋白

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T4677	MMAD Monomethylauristatin D,Demethyldolastatin 10,单甲基澳瑞他汀 D,Monomethyl Dolastatin 10	Microtubule Associated; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	MMAD (Demethyldolastatin 10) 是一种有效的微管蛋白抑制剂，是抗体药物偶联物中的一种毒素有效载荷。
T18869	Vat-Cit-PAB-Monomethyl Dolastatin 10	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	Vat-Cit-PAB-Monomethyl Dolastatin 10 is an ADC linker-conjugated drug designed to deliver potent antitumor activity. It achieves this through Monomethyl Dolastatin 10, a potent tubulin inhibitor, connected via the Vat-Cit-PAB ADC linker.

化合物

MMAD

Cat.No: T4677

Synonym: Monomethylauristatin D,Demethyldolastatin 10,单甲基澳瑞他汀 D,Monomethyl Dolastatin 10

Target: Microtubule Associated, ADC Cytotoxin

Vat-Cit-PAB-Monomethyl Dolastatin 10

Cat.No: T18869

Synonym:

Target: Others, Drug-Linker Conjugates for ADC

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02300	BIN1 Protein, Human, Recombinant (His) AMPHL,bridging integrator 1,AMPH2,SH3P9	Human	E. coli
	Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicated in rare and common diseases affecting different tissues and physiological functions. BIN1 downregulation is linked to cancer progression and also correlates with ventricular cardiomyopathy and arrhythmia preceding heart failure. Increased BIN1 expression is linked to increased...
TMPY-01751	DR3/TNFRSF25 Protein, Human, Recombinant (hFc) TRAMP,TR3,WSL-1,TNFRSF12,DR3,WSL-LR,tumor necrosis factor re...	Human	HEK293 Cells
	DR3/TNFRSF25 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.
TMPY-05760	DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated TRAMP,tumor necrosis factor receptor superfamily, member 25,...	Human	HEK293 Cells
	DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.
TMPY-00961	ADAM15 Protein, Human, Recombinant (His) MDC15,ADAM metallopeptidase domain 15	Human	HEK293 Cells
	ADAM15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is Q13444-10.

重组蛋白

BIN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02300

Species: Human

Expression System: E. coli

DR3/TNFRSF25 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01751

Species: Human

Expression System: HEK293 Cells

DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05760

Species: Human

Expression System: HEK293 Cells

ADAM15 Protein, Human, Recombinant (His)

Cat.No: TMPY-00961

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T10947	D8-MMAD Monomethylauristatin D D8,Demethyldolastatin 10 D8,Monomethyl Dolastatin 10 D8	Others	Others
	D8-MMAD is a deuterated form of MMAD, which is a microtubule destroyer.