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Search Results for " microvasculature "

Targets Recommended: Integrin

4

抑制剂 & 化合物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6812L	Cyclo(-RGDfK) TFA	Integrin	Cytoskeletal Signaling
	Cyclo(-RGDfK) TFA 是一种选择性整合素αvβ3的有效抑制剂，其IC50值为 0.94 nM。它通过与细胞表面的 αvβ3 整合素结合，特异性靶向肿瘤微血管和癌细胞。
T6812	Cyclo(-RGDfK) Cyclo (-RGDfK)	Integrin	Cytoskeletal Signaling
	Cyclo(-RGDfK) (Cyclo (-RGDfK)) 是一种选择性整合素αvβ3的有效抑制剂，IC50值为 0.94 nM。它通过与细胞表面的 αvβ3 整合素结合，特异性靶向肿瘤微血管和癌细胞。
T2064	Semaxinib 司马沙尼,SU5416	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Semaxinib (SU5416) 是一种选择性的 VEGFR(Flk-1/KDR) 抑制剂，其 IC50=1.23 μM。
T68400	STA-9584	Others	Others
	STA-9584 is a potent vascular disrupting agent, which exhibits potent antitumor activity by selectively targeting microvasculature at both the center and periphery of tumors. In vitro, 2-methoxy-5-(5-(3,4,5-trimethoxyphenyl)isoxazol-4-yl)aniline (STA-9122) (active metabolite of STA-9584 ) displayed increased potency relative to other tubulin-binding agents and was highly cytotoxic to tumor cells. STA-9584 induced significant tumor regressions in prostate and breast xenograft models in vivo and, ...

化合物

Cyclo(-RGDfK) TFA

Cat.No: T6812L

Target: Integrin

Cat.No: T6812

Synonym: Cyclo (-RGDfK)

Target: Integrin

Cat.No: T2064

Synonym: 司马沙尼,SU5416

Target: VEGFR

Cat.No: T68400

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02574	Chymase 1 Protein, Human, Recombinant (His) MCT1,chymase 1, mast cell,chymase,CYH	Human	Baculovirus Insect Cells
	The STR polymorphism in the CMA1 gene is associated with asthma and that this association is even stronger with atopic asthma. CMA1 and IL-4 in atopic asthma and for IL-4 in atopy in general. The local angiotensin II system (LAS) has numerous functions, including the regulation of growth and differentiation in the gastrointestinal tract. Angiotensin II (AngII) may be generated by angiotensin-I-converting enzyme (ACE) or mast cell chymase (CMA1) and plays an important role in inflammatory process...
TMPY-01996	SorCS1 Protein, Human, Recombinant (His) hSorCS,RP11-446H13.1,sortilin-related VPS10 domain containin...	Human	HEK293 Cells
	VPS1 domain-containing receptor SorCS1, also known as SORCS1 and SORCS, is a single-pass type I membrane protein that belongs to the SORCS family and SORCS1 subfamily. SORCS1 contains five BNR repeats and one PKD domain. SorCS1 is a member of the Vps1p-domain receptor family comprised of Sortilin, SorCS1, SorCS2, SorCS3, and SorLA. The common characteristic of these receptors is an N-terminal Vps1p domain, which either represents the only module of the luminal/extracellular moiety or is combined...

重组蛋白

Chymase 1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02574

Species: Human

Expression System: Baculovirus Insect Cells

SorCS1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01996

Species: Human

Expression System: HEK293 Cells

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