Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70288 |
Methophenazine diethanesulfonate
|
Others | Others |
Methophenazine diethanesulfonate is a Calmodulin antagonist. | |||
T70287 |
BMS-186511
|
Others | Others |
BMS-186511 is a Farnesyltransferase (FT) inhibitor with potential anticancer activity. BMS-186511 is a bisubstrate analogue inhibitor of FT, would inhibit the malignant growth properties of a cell line established from malignant schwannoma of an NF1 patient. Following treatment with BMS-186511 , ST88-14 cells became flat, nonrefractile, were contact-inhibited, and lost their ability to grow in soft agar. BMS-186511 was found to specifically inhibit FT, but not geranylgeranyltransferase I, a clos... |