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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T38443 Methoctramine tetrahydrochloride

Others Others
Methoctramine tetrahydrochloride is a potent and cardioselective antagonist of the M2 muscarinic receptor, capable of inhibiting Muscarine-induced bradycardia in vivo.
T37728 Methoctramine (hydrate)

Others Others
Methoctramine is a selective antagonist of M2 muscarinic acetylcholine receptors (IC50 = 6.1 nM in CHO-K1 cell membranes).[1] It is selective for M2 over M1, M3, M4, and M5 receptors (IC50s = 92, 770, 260, and 217 nM, respectively). In vitro, methoctramine inhibits acetylcholine-induced reductions in isolated guinea pig tracheal tube contractions when used at a concentration of 1 μM.[2] In vivo, methoctramine inhibits bradycardia and bronchoconstriction induced by acetylcholinein guinea pigs wit...

化合物

Methoctramine tetrahydrochloride
Cat.No: T38443
Synonym:
Target: Others
Methoctramine (hydrate)
Cat.No: T37728
Synonym:
Target: Others
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