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Targets Recommended: CaMK Dopamine Receptor 5-HT Receptor Adrenergic Receptor Histamine Receptor

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抑制剂 & 化合物

1

化合物库

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重组蛋白

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Cat. No. Product Name
L2300 离子通道库

931 compounds
931 种与离子通道相关的生物活性小分子化合物的特有集合,用于离子通道相关的疾病和药物研究,可用于高通量筛选和高内涵筛选;

化合物库

离子通道库
Cat.No: L2300
Compounds: 931
Cat. No. Product Name Target Signaling Pathways
T1090 Perphenazine

Perphenazin,Etaperazine,Trilafon,奋乃静

CaMK; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Perphenazine (Trilafon) 是吩噻嗪衍生物和多巴胺拮抗剂,具有止吐和抗精神病特性。它能够抑制5-HT2A 受体,α1A 肾上腺素能受体,多巴胺D2、D3、D2L 受体,以及组胺H1受体,对应的Ki 值分别为5.6、10、0.765、0.13、3.4 和 8 nM。
T11043 Dihydroergocristine mesylate

甲磺酸双氢麦角汀,DHEC (mesylate)

Beta Amyloid Neuroscience
Dihydroergocristine mesylate (DHEC (mesylate)) 是一种 γ-secretase (GSI) 的抑制剂,能够阿尔茨海默氏病淀粉样蛋白 β 肽 (amyloid-β) 的产生,与 γ-secretase 和 Nicastrin 结合的平衡解离常数 (Kd) 值分别为 25.7 nM 和 9.8 μM。
T37768 β-Amyloid (1-37) (human)

β-Amyloid (1-37) (human) 与阿尔茨海默病的精神状态有潜在关联。

化合物

Perphenazine
Cat.No: T1090
Synonym: Perphenazin,Etaperazine,Trilafon,奋乃静
Target: CaMK, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
Dihydroergocristine mesylate
Cat.No: T11043
Synonym: 甲磺酸双氢麦角汀,DHEC (mesylate)
Target: Beta Amyloid
β-Amyloid (1-37) (human)
Cat.No: T37768
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00732 ASS1 Protein, Human, Recombinant (His)

Citrulline--Aspartate Ligase,Argininosuccinate Synthase,ASS1...

Human E. coli
Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullin...

重组蛋白

ASS1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00732
Species: Human
Expression System: E. coli
TargetMol Loading
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