Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11992 |
Mefuparib hydrochloride
MPH |
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Mefuparib hydrochloride induces apoptosis and possesses prominent anticancer activity in vitro and in vivo. Mefuparib hydrochloride (MPH) is an orally active, substrate-competitive and selective PARP1/2 inhibitor with IC50s of 3.2 nM and 1.9 nM, respectively. | |||
T70785 |
Mefuparib Free Base
|
Others | Others |
Mefuparib Free Base is a potent, highly selective, competitive PARP1/2 inhibitor with IC50 of 3.2/1.9 nM, respectively. Mefuparib (CVL218), has been shown to have promising antiviral activity against the virus that causes COVID-19. |