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Targets Recommended: Potassium Channel Calcium Channel GABA Receptor Sodium Channel GluR Carbonic Anhydrase iGluR

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Cat. No. Product Name Target Signaling Pathways
T0675 Topiramate

RWJ 17021,McN 4853,托吡酯

Potassium Channel; Calcium Channel; GABA Receptor; Sodium Channel; GluR; Carbonic Anhydrase; iGluR Membrane transporter/Ion channel; Metabolism; Neuroscience
Topiramate (RWJ 17021) 是一种GluR5受体拮抗剂,可通过增强GABAergic 活性,抑制kainate/AMPA 受体,抑制钠和钙通道的电压敏感,增加钾电导并抑制碳酸酐酶来产生抗癫痫作用,用于治疗部分性和全身性癫痫发作。
T61145 Topiramate lithium

Others Others
Topiramate lithium (McN 4853) is a wide-ranging antiepileptic compound with GluR5 receptor antagonistic properties. Its mechanism of action involves enhancing GABAergic activity, inhibiting kainate/AMPA receptors, voltage-sensitive sodium and calcium channels, and increasing potassium conductance. Additionally, this compound inhibits carbonic anhydrase. [1][2][3]

化合物

Topiramate
Cat.No: T0675
Synonym: RWJ 17021,McN 4853,托吡酯
Target: Potassium Channel, Calcium Channel, GABA Receptor, Sodium Channel, GluR, Carbonic Anhydrase, iGluR
Topiramate lithium
Cat.No: T61145
Synonym:
Target: Others
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