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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9102 |
WM-3835
|
Apoptosis; Histone Methyltransferase; Histone Acetyltransferase | Apoptosis; Chromatin/Epigenetic |
WM-3835 是一种高特异性 HBO1(KAT7orMYST2) 抑制剂,可直接与 HBO1 33 的乙酰辅酶 A 结合位点结合 WM-3835 激活细胞凋亡,抑制骨肉瘤细胞的增殖,迁移和侵袭。它抑制小鼠中骨肉瘤异种移植物的生长,有抗肿瘤活性。 | |||
T8681 |
HA-1004 dihydrochloride
|
Calcium Channel; PKA; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism; Tyrosine Kinase/Adaptors |
HA-1004 dihydrochloride 是 PKA、PKC、cGKI、MYLK 和钙通道蛋白的抑制剂。 | |||
T27525 |
HA-1004
|
Serine/threonin kinase; PKA; PKC | Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Tyrosine Kinase/Adaptors |
HA-1004是一种 PKG,PKA,PKC 和 MLC 的激酶抑制剂。 | |||
T68329 |
HA-1004 HCl
|
Others | Others |
HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03753 |
MYLK Protein, Human, Recombinant (His)
MYLK,Myosin light chain kinase, smooth muscle,Telok... |
Human | E. coli |
Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscl... | |||
TMPH-00379 |
MLCK Protein, Chicken, Recombinant (His & Myc & SUMO)
Mylk,Telokin,Myosin light chain kinase, smooth musc... |
Chicken | E. coli |
Phosphorylates a specific serine in the N-terminus of a myosin light chain, which leads to the formation of calmodulin/MLCK signal transduction complexes which allow selective transduction of calcium signals. MLCK Protein, Chicken, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 52.9 kDa and the accession number is P11799. |