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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21550 |
Blebbistatin
(±)-Blebbistatin |
ATPase; Myosin | Cytoskeletal Signaling; Membrane transporter/Ion channel |
Blebbistatin ((±)-Blebbistatin) 是一种选择性的非肌肉肌球蛋白 II 抑制剂,可促进角膜内皮细胞 (CEC) 的定向迁移并加速伤口愈合,并保留了细胞连接的完整性和屏障功能。Blebbistatin 是 MYH9 抑制剂。 | |||
T12503 |
(+)-Blebbistatin
|
Others | Others |
(+)-Blebbistatin 是 (–)-Blebbistatin 的非活性对映异构体。 (–)-Blebbistatin 是一种选择性肌球蛋白 II ATPase 抑制剂。 | |||
T6038 |
(-)-Blebbistatin
(S)-(-)-Blebbistatin |
ATPase; Myosin | Cytoskeletal Signaling; Membrane transporter/Ion channel |
(-)-Blebbistatin ((S)-(-)-Blebbistatin) 是 blebbistatin 的 S 对映异构体。(-)-Blebbistatin 是一种肌球蛋白 II 抑制剂 (IC50=0.5-5 μM),具有有效性和选择性。(-)-Blebbistatin 可以用于抑制心肌肌球蛋白、非肌肉肌球蛋白II和骨骼肌肌球蛋白。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01729 |
Myosin-9/MYH9 Protein, Human, Recombinant (GST)
Myosin-9,MYH9,Myosin heavy chain ... |
Human | E. coli |
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Required for cortical actin clearance prior to oocyte exocytosis. Promotes cell motility in conjunction with S100A4. During cell spreading, plays an important role in cytoskeleton reorganization, focal contact formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10. Myosin-... | |||
TMPJ-01456 |
Mucin-17/MUC17 Protein, Human, Recombinant (His)
Mucin-17, MUC-17, MUC17, MUC3, MUC-3 |
Human | HEK293 Cells |
Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favourable prognosis for patients. And that p38 signalling is a key factor involved in MUC17-mediated inhibition of GC cell proliferation and protection against inflammatory stimulation, MUC17 upregulates the expression ... |