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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12398 |
MP7
PDK1 抑制剂,PDK1 inhibitor |
PDK | PI3K/Akt/mTOR signaling |
MP7 (PDK1 inhibitor) 是磷酸肌醇依赖性激酶-1 (PDK1) 抑制剂。 | |||
T11872L |
LMP744 hydrochloride
NSC706744 hydrochloride,MJ-III65 hydrochloride |
Topoisomerase | DNA Damage/DNA Repair |
LMP744 hydrochloride (NSC-706744 hydrochloride) 是一种是拓扑异构酶 1 抑制剂,显示出抗肿瘤的活性。 | |||
T13172 |
TMP780
|
ROR | Metabolism |
TMP780 is an inverse RORγt agonist (IC50: 13 nM). RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders. | |||
T11872 |
LMP744
NSC706744,MJ-III65 |
Others | Others |
LMP744 is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity. | |||
T13172L | TMP778 | Others | Others |
TMP778 is an effective and selective RORγt inverse agonist (IC50: 7 nM in FRET assay). | |||
T81921 |
LMP7-IN-2
|
Others | Others |
LMP7-IN-2, 作为LMP7抑制剂,适用于相关炎症性疾病与失调的治疗。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01081 |
CHMP7 Protein, Human, Recombinant (His)
Charged multivesicular body protein 7,Chromatin-mod... |
Human | E. coli |
ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Plays a role in the endosomal sorting pathway. CHMP7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 56.9 kDa and the accession number is Q8WUX9. |