316
59
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Cat. No. | Product Name | ||
---|---|---|---|
L6700 | 抗癌天然产物库 | 1772 compounds | |
1772 种已知活性天然产物的独特集合,是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具,可用于HTS 和HCS。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77006 |
Felzartamab
TJ-202,MOR-03087,MOR-202 |
CD38 | Immunology/Inflammation |
Felzartamab(MOR-202) 是一种人源靶向 CD38 的单克隆抗体,可用于研究多发性骨髓瘤和晚期抗体介导的同种异体肾移植排斥反应。 | |||
T77125 |
Otilimab
GSK 3196165,MOR103 |
CSF-1R | Tyrosine Kinase/Adaptors |
Otilimab (GSK 3196165) 是一种人源化抗粒细胞-巨噬细胞集落刺激因子 (GM-CSF) 单克隆抗体。Otilimab 具有抗炎活性,通过阻断 GM-CSF 与其细胞表面受体的相互作用来调节 GM-CSF 的生物学功能,可用于研究治疗重症 COVID-19 肺炎。 | |||
T77135 |
Tafasitamab
MOR00208,XmAb5574,Tafasitamab-cxix |
Apoptosis; Immunology/Inflammation related | Apoptosis; Immunology/Inflammation |
Tafasitamab (XmAb5574) 是一种 Fc 修饰的人源化单克隆抗体,靶向人 B 细胞表面抗原 CD19 ,可用于研究弥漫性大B细胞淋巴瘤。 | |||
T79547 |
MOR agonist-2
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
MOR agonist-2 (Compound 46) 为D3R拮抗剂及MOR激动剂,其Ki值分别为7.26 nM和564 nM。MOR agonist-2潜在以MOR部分激动机制实现镇痛效果,并通过D3R拮抗降低阿片类药物的滥用风险。 | |||
T79060 |
MOR agonist-1
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
MOR agonist-1为一种针对MOR(μ-opioid receptor)的激动剂,展现出优秀的镇痛效果,适用于疼痛及其相关疾病的研究应用。 | |||
T81763 |
MOR agonist-3
|
Others | Others |
MOR Agonist-3 (Compound 84) 是一种双重作用化合物,具有D3R/MOR拮抗活性(Ki值为55.2 nM和382 nM)。该化合物其MOR部分激动性质展现出镇痛潜力,并可能通通过D3R拮抗作用降低阿片类药物的滥用风险。MOR Agonist-3 亦适用于炎症治痈和神经性疼痛的研究领域。 | |||
T12151 |
N-Methylmoranoline
MOR 14,N-Methyl-1-deoxynojirimycin,N-Methylmoranolin |
Others | Others |
N-Methylmoranoline is an inhibitor of α-glucosidase. | |||
T78778 |
D3R/MOR antagonist 1
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
D3R/MOR antagonist 1 (Compound 114) 为D3R/MOR拮抗剂,其对D3R和MOR的Ki值分别为46.5 nM和691 nM。该化合物通过MOR的部分激动作用可能具有镇痛效果,同时通过D3R的拮抗作用有助于降低阿片类药物的滥用风险。 | |||
T78779 |
D3R/MOR antagonist 2
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
D3R/MOR antagonist 2(Compound 121)为一种D3R/MOR拮抗剂,其Ki值分别为46.5 nM及691 nM。该化合物通过MOR部分激动作用可产生镇痛效果,并通过D3R拮抗减少阿片类药物的潜在滥用风险。 | |||
T7748 |
Dermorphin TFA
皮啡肽三氟乙酸盐 |
Others; Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience; Others |
Dermorphin TFA 是在两栖类皮肤中发现的天然七肽,是 μ-阿片受体激动剂,可用于抑制神经痛。 | |||
T7404 |
Dermorphin
皮啡肽 |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Dermorphin 是在两栖类皮肤中发现的天然七肽,是 μ-阿片受体激动剂,可用于抑制神经痛。 | |||
T7218 |
Endomorphin 2
内吗啡肽 2 |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Endomorphin 2 是一种高亲和力和选择性的 μ-阿片受体激动剂,对 kappa3 结合位点具有合理的亲和力 ,Ki 为 20 到 30 nM 之间。 | |||
T40684 |
N-Nitrosomorpholine
|
Others | Others |
N-Nitrosomorpholine 是一种亚硝胺,具有光敏感性。它对动物有强致癌作用。 | |||
T19636 |
Morniflumate
马尼氟酯,Niflam,UP 164,UP-164,Morniflu,UP164 |
Others | Others |
Morniflumate (Niflam) 是一种非甾体抗炎药。它用于治疗炎症。 | |||
T10319 |
Anamorelin
RC-1291,阿拉莫林,ONO-7643 |
GHSR | GPCR/G Protein |
Anamorelin (ONO-7643) 是新型ghrelin receptor 激动剂,根据FLIPR 检测,得到其EC50=0.74 nM。 | |||
T1977 |
Dorsomorphin
Compound C,BML-275 |
AMPK; Autophagy; TGF-beta/Smad | Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Stem Cells |
Dorsomorphin (BML-275) 是一种 AMPK 抑制剂 (Ki=109 nM),具有选择性和 ATP 竞争性。Dorsomorphin 可以抑制 BMP I 型受体 ALK2、ALK3 和 ALK6。Dorsomorphin 可诱导自噬,具有抗肿瘤活性。 | |||
TQ0178 |
Flumorph
氟吗啉,SYP-L190 |
Antifungal | Microbiology/Virology |
Flumorph (SYP-L190) 是一种羧酸酰胺杀菌剂。 | |||
T9046 |
Morpholinylmercaptobenzothiazole
|
Others | Others |
Morpholinylmercaptobenzothiazole 是一种后效快速硫化促进剂。 | |||
T50076 |
Antitumor agent-130
|
Others | Others |
(2E)-3-(3,5-dimethoxyphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one 又称DMPVP,是一种新型的合成化合物,属于卡西酮类,具有精神活性。 | |||
T10341 |
Antitumor agent-19
|
Others | Others |
Antitumor agent-19 是一种肿瘤相关巨噬细胞的调节剂,在 RAW 264.7 细胞和 BMDM 细胞中的 EC50 分别为 17.18 μM 和 18.87 μM。 | |||
T9000 |
Pyrimorph
|
Antifungal | Microbiology/Virology |
Pyrimorph 是一种杀真菌剂,对 oomycetes 具有良好抑菌活性。 | |||
T11013L2 |
Levorotation nimorazole phosphate ester TFA
|
Others | Others |
Levorotation nimorazole phosphate ester TFA 是一种抗厌氧菌和抗原虫感染的试剂。 | |||
T7112 |
Ibutamoren Mesylate
MK-0677,伊布莫仑甲磺酸盐,MK-677 |
GHSR | GPCR/G Protein |
Ibutamoren Mesylate (MK-0677) 是非肽段类生长激素促分泌素受体 (GHSR) 激动剂,也是一种口服有活性的生长激素 (GH) 促分泌素。 | |||
TQ0267 |
Endomorphin 1
内吗啡肽 1,Endomorphin-1 |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Endomorphin 1 是一种高亲和力和选择性的 μ-阿片受体激动剂,对 kappa3 结合位点具有合理的亲和力 ,Ki 为 20 到 30 nM 之间。 | |||
T12096L |
Morinidazole
|
Antibacterial | Microbiology/Virology |
Morinidazole 具有抗菌活性,可用于厌氧菌引起的阑尾炎、盆腔炎等细菌感染研究。 | |||
TQ0022 |
Capromorelin Tartrate
卡普瑞林酒石酸盐,CP 424391-18 |
GHSR | GPCR/G Protein |
Capromorelin Tartrate (CP 424391-18) 是口服有活性的 growth hormone secretagogue receptor 有效激动剂,能够作用于 hGHS-R1a(Ki:7 nM)。 | |||
T79209 |
Ogremorphin
OGM,GPR68-IN-1 |
GPR | Endocrinology/Hormones; GPCR/G Protein |
Ogremorphin (OGM) 为一种具有选择性和高效性的 GPR68 抑制剂(EC50:170 nM),可用于研究自身免疫性慢性炎症疾病。 | |||
T34281 |
Relamorelin
BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131 |
GHSR | GPCR/G Protein |
Relamorelin (RM-131)是一种具有选择性和有效性的生长素释放肽/生长激素促分泌素受体 (GHSR) 激动剂,是一种有效的生长素释放肽模拟物,对 GHS-1a 受体具有很高的亲和力。Relamorelin 是一种具有中枢渗透性的五肽,可增加生长激素水平,加速胃排空,具有研究恶病质的潜力。 | |||
T77687 |
3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one
|
Others | Others |
3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one 在人结肠癌细胞系中显示出抗肿瘤活性,可能用于防治血栓。 | |||
T60162 |
1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl]
|
Others | Others |
1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl]是一种抗纤维化的化合物。 | |||
T9132 |
Emorfazone
依莫法宗,PH011085 |
Others | Others |
Emorfazone (PH011085) 具有抗伤害作用。 | |||
T8415 |
4-Benzyl-2-carboxymorpholine hydrochloride
|
Others | Others |
4-Benzyl-2-carboxymorpholine hydrochloride 是一种用于蛋白质组学研究应用的专业产品,来自 Santa Cruz。 | |||
T0363 |
Morantel tartrate
CP-12009-18 tartrate,UK 296418 tartrate,酒石酸甲噻嘧啶 |
Parasite | Microbiology/Virology |
Morantel tartrate (CP-12009-18 tartrate) 是一种主要用于牲畜的杀虫剂。 | |||
T0187 |
Amorolfine hydrochloride
Amorolfin,盐酸阿莫洛芬,Amorolfine HCl,盐酸阿莫罗芬,Ro 14-4767/002 |
Antibiotic; Antifungal | Microbiology/Virology |
Amorolfine hydrochloride (Amorolfine HCl) 是一种抗真菌剂。 | |||
T5027 |
Dimemorfan phosphate
二甲啡烷磷酸盐,3,17-dimethylmorphinan |
Sigma receptor | GPCR/G Protein |
Dimemorfan phosphate (3,17-dimethylmorphinan) 是 sigma 1 受体激动剂,用作强效镇咳药。 | |||
TP1251L |
N-terminally acetylated Endomorphin-1 acetate
Ac-L-Tyr-L-Pro-L-Trp-L-Phe-CONH2 |
Others | Others |
N-terminally acetylated Endomorphin-1 acetate (Ac-L-Tyr-L-Pro-L-Trp-L-Phe-CONH2) 是一种修饰的 Endomorphin-1。 | |||
T7809L |
Ipamorelin 2 Pivalic acid
NNC-26-0161 |
Others | Others |
Ipamorelin 2 Pivalic acid (NNC-26-0161) 是一种生长激素释放肽,可诱导大鼠纵向骨生长。 | |||
T60106 |
2,5-Morpholinedione, 4-methyl-6-(1-methylethyl)-3-(phenylmethyl)-
|
Others | Others |
2,5-Morpholinedione, 4-methyl-6-(1-methylethyl)-3-(phenylmethyl)- 是 Lateritin 的反式结构。 | |||
T10342 |
Antitumor agent-2
|
Others | Others |
Antitumor agent-2 具有抗炎和抗肿瘤活性,可用于研究癌症。 | |||
T0636 |
4-Methylmorpholine N-oxide
|
Others | Others |
4-Methylmorpholine N-oxide 常用作氧化反应中的共氧化剂和牺牲催化剂。 | |||
T77686 |
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone
|
Antifungal | Microbiology/Virology |
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone 具有广谱的抗真菌活性,对白色念珠菌、黑曲霉、铜绿假单胞菌、金黄色葡萄球菌等具有抑制作用。 | |||
T23116 |
Oxotremorine sesquifumarate
|
AChR | Neuroscience |
Oxotremorine sesquifumarate 是一种毒蕈碱受体激动剂,对 M2 的激活作用更强,可用于神经学研究。 | |||
T0090 |
Moroxydine hydrochloride
盐酸吗啉胍,ABOB hydrochloride,病毒灵,Moroxydine HCl |
Antiviral; Influenza Virus | Immunology/Inflammation; Microbiology/Virology |
Moroxydine hydrochloride (ABOB hydrochloride) 是一种合成的杂环双胍类抗病毒药物。 它具有抗病毒活性,有助于预防和治疗流感。 | |||
T4469 |
Nemorubicin
Methoxymorpholinyldoxorubicin,PNU-152243A,PNU 152243,奈莫柔比星 |
Others | Others |
Nemorubicin (PNU 152243) 是一种 Doxorubicin 衍生物,具有抗肿瘤活性。它需要完整的核苷酸切除修复系统才能发挥活性。它对多药耐药表型的多种肿瘤细胞系具有细胞毒性。 | |||
T2613 |
Almorexant
阿莫伦特,ACT 078573 |
OX Receptor | GPCR/G Protein; Neuroscience |
Almorexant (ACT 078573) 是一种有效的竞争性食欲素 1 受体 (OX1)/食欲素 2 受体 (OX2) 双重拮抗剂,OX1 和 OX2 的 Ki 值分别为 1.3 和 0.17 nM。 | |||
T17217 |
Vamorolone
地塞米松EP杂质E,VBP15 |
Glucocorticoid Receptor; NF-κB | Endocrinology/Hormones; NF-κB |
Vamorolone (VBP15) 是一种首创的,具有口服活性的解离性类固醇 (dissociative steroidal) 抗炎药和膜稳定剂。它抑制 (NF-κB) 抑制作用,并降低了激素的影响。它改善肌营养不良,无副作用。 | |||
T12339 |
Oxotremorine M iodide
碘化氧化震颤素M,Oxotremorine methiodide |
AChR | Neuroscience |
Oxotremorine M iodide (Oxotremorine methiodide) 是 mAChR 的激动剂,可增强 NMDA 受体。 | |||
TP1404L |
Hemorphin-7 acetate(152685-85-3 free base)
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Hemorphin-7 acetate(152685-85-3 free base) 是一种 hemorphin 肽,一种源自血红蛋白 β 链的内源性阿片肽。 Hemorphin 肽具有镇痛和抗高血压活性,可激活阿片受体并抑制血管紧张素转换酶 (ACE)。 | |||
T21660L |
b-Casomorphin (1-3) Acetate
b-Casomorphin (1-3) Acetate (72122-59-9 Free base) |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
b-Casomorphin (1-3) Acetate 是一种具有阿片样物质作用的三肽。 | |||
T12097 |
Morphothiadin
GLS4,莫非赛定 |
HBV | Microbiology/Virology |
Morphothiadin (GLS4) 是一种有效的抑制野生型和阿德福韦耐药 HBV 复制的抑制剂,IC50值为 12 nM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1949 |
Moracin C
桑辛素 C,5-(6-羟基-2-苯并呋喃基)-2-(3-甲基-2-丁烯基)-1,3-苯二醇 |
ROS; NO Synthase | Immunology/Inflammation |
Moracin C 是一种发现于Morus mesozygia、Morus alba var. multicaulis 中的天然化合物,是一种抗炎剂。Moracin C 可抑制细胞中的一氧化氮(NO)释放和LPS 激活的活性氧(ROS)。 | |||
TN1253 |
3-hydroxymorindone
|
Others | Others |
3-hydroxymorindone 是一种来自海巴戟 Morinda citrifolia 的天然产物。 3-hydroxymorindone 是一种色素。 | |||
T5S1607 |
Morusin
Mulberrochromene,桑辛素 |
NF-κB; Antibacterial; STAT | JAK/STAT signaling; Microbiology/Virology; NF-κB; Stem Cells |
Morusin (Mulberrochromene) 是从M. australis 分离的去乙烯基化黄酮,可抑制NF-κB 和STAT3的活性,具有抗菌、抗肿瘤、抗氧化等各种生物活性。 | |||
T2835 |
Morin
桑色素,Toxylon pomiferum,Aurantica,Calico Yellow,Al-Morin |
Others | Others |
Morin (Calico Yellow) 是植物性黄酮类化合物,具有较弱的抗氧化活性,是用于铝物种形成的荧光螯合剂。 | |||
T3410 |
Momordin Ic
地肤子皂苷Ic,地肤子皂苷 Ic,Momordin 1c |
Apoptosis; MAPK; PI3K | Apoptosis; MAPK; PI3K/Akt/mTOR signaling |
Momordin Ic (Momordin 1c) 是山茱萸的主要皂苷成分,通过氧化应激调控线粒体功能障碍诱导细胞凋亡,具有抗癌活性。 | |||
TN1950 |
Moracin M
|
PDE | Metabolism |
Moracin M 是桑白皮中的一种酚类成分,有效的磷酸二酯酶 4 (PDE4) 抑制剂,对于 PDE4D2,PDE4B2,PDE5A1 和 PDE9A2 的 IC50 分别为 2.9 μM,4.5 μM,> 40 μM 和 > 100 μM。Moracin M 具有抗炎活性。 | |||
T3414 |
Morroniside
莫诺苷,奎宁树 |
Apoptosis; MMP; Pyroptosis | Apoptosis; Immunology/Inflammation; Proteases/Proteasome |
Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用,可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。 | |||
TN1112 |
Morellic acid
|
Others | Others |
Morellic acid 提取于 Garcinia Morella 中,具有抗血管生成作用。 | |||
TN4583 |
Moringin
|
gp120/CD4; IL Receptor; BCL; GSK-3; TNF; Wnt/beta-catenin; Caspase; COX; Nrf2; PPAR; p53 | Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells |
Moringin 是一种异硫氰酸酯,由 Moringa oleifera 种子中存在的硫代葡萄糖苷前体 glucoMoringin 通过黑芥子酶介导水解获得。Moringin 具有抗炎和抗氧化特性。 | |||
T15355 |
Fumitremorgin C
烟曲霉毒素c,12α-Fumitremorgin C |
BCRP; Antibacterial; Antibiotic; ABC | Membrane transporter/Ion channel; Microbiology/Virology |
Fumitremorgin C (12α-Fumitremorgin C) 是ABCG2/BRCP 的选择性抑制剂。 | |||
TN2500 |
1,5,15-Tri-O-methylmorindol
|
Others | Others |
1,5,15-Tri-O-methylmorindol has effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA. | |||
TN4631 |
Nemorensine
|
Others | Others |
Nemorensine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4631,CAS号为 50906-96-2。 | |||
TN4630 |
Nemoralisin
|
Others | Others |
Nemoralisin exhibits weak cytotoxicities (IC50>10 uM) against HepG2, AGS, MCF-7, and A-549 cancer cell lines. | |||
TN4629 |
Nemoralisin C
|
Others | Others |
Nemoralisin C shows antiproliferative activity against HepG2, AGS, MCF-7, and A-549 cancer cell lines. | |||
TN1583 |
Dihydromorin
|
TRP/TRPV Channel | Membrane transporter/Ion channel |
trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma system may not be effective on normal melanocytes, indicating that a non-tumor melanocyte system is more suitable for the screening o | |||
TN3744 |
Cyclomorusin
|
NOS; AChR | Immunology/Inflammation; Neuroscience |
Cyclomorusin exhibits competitive inhibition toward monophenolase activity of mushroom tyrosinase, the IC50 value of 0.092 microM. It evokes the stimulation of superoxide anion generation in fMLP-stimulated rat neutrophils. Cyclomorusin , neocyclomorusin | |||
TN1945 |
Momordicoside K
|
Others | Others |
Momordicoside K has antidiabetic activity. | |||
TN4581 |
Moracin D
|
c-Myc; TNF; COX; Antifection | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; Microbiology/Virology; Neuroscience |
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis. | |||
TN5515 |
Morelloflavone
|
||
Morelloflavone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5515,CAS号为 16851-21-1。 | |||
T79940 |
Moracin N
|
Glutathione Peroxidase | Metabolism |
Moracin N, 一种可从桑叶中分离的铁死亡抑制剂,通过抑制氧化应激以发挥神经保护作用。 | |||
TN1940 |
Momordicine I
|
Others | Others |
Momordicine I has anti-diabetic and antifeedant activities. | |||
TN6863 |
Momordin IIc
|
||
Momordin IIc is a natural product. | |||
TN1942 |
Momordicoside F1
苦瓜皂苷 F1 |
Others | Others |
Momordicoside F1 may have antiproliferative activities against MCF-7, WiDr, HEp-2, and Doay human tumor cell lines. | |||
TN6323 |
7α-O-Methylmorroniside
|
||
7α-O-Methylmorroniside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6323,CAS号为 119943-45-2。 | |||
TN6544 |
24-Hydroxymomordicine III
|
||
24-Hydroxymomordicine III 可用于生命科学领域的相关研究,其产品编号为 TN6544。 | |||
TN1944 |
Momordicoside I aglycone
|
Others | Others |
Momordicoside I aglycone is a natural product | |||
TN4312 |
Isomorellic acid
|
Others | Others |
Isomorellic acid is a cytotoxic caged xanthone. | |||
TN4084 |
Fumitremorgin B
|
Antifection | Microbiology/Virology |
Fumitremorgen B is a mycotoxin, it exhibits a certain degree of genotoxicity, it can cause DNA damage in human lymphocytes; it shows an inhibitory activity on the cell cycle progression of mouse tsFT210 cells in the M phase, with the MIC value of 26.1 mic | |||
TN4585 |
Moronic acid
|
HIV Protease; Antifection; HSV | Microbiology/Virology; Proteases/Proteasome |
Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186) and was modified to develop more potent anti-AIDS agents. Moronic acid is a new structural lead for anti-EBV drug development, can substantially reduce the numbers of EBV particles produced by the cells after lytic induction. Morolic and moronic acids have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an... | |||
T79937 |
Mortatarin F
|
Glucosidase | Metabolism |
Mortatarin F (Compound 1) 是一种具有戊烯基化类黄酮结构的葡萄糖苷酶抑制剂,其IC50值为8.7 μΜ。该化合物可从桑叶中提取,并应用于研究降低血糖效果。 | |||
T79938 |
Mortatarin G
|
Glucosidase | Metabolism |
Mortatarin G (compound 3),一种桑叶中分离得到的异戊二烯化黄酮类化合物,显示出显著的α-葡萄糖苷酶抑制效果,其IC50值为20.4±1.4 μM。 | |||
TN4577 |
Momordicoside X
|
Others | Others |
Momordicoside X displays moderate insulin secretion activity. | |||
TN1943 |
Momordicoside G
|
Others | Others |
Momordicosides K and L, the main bitter taste triterpene glycosides in Bitter melon; and bitter melon has been reported to have hypoglycemic, anti atherogenic and anti HIV activities. | |||
TN1330 |
7-O-Ethylmorroniside
7-乙氧基莫诺苷,7-O-ethyl-morroniside,7-氧乙基莫诺苷,金银花 |
Others | Others |
7-O-ethyl-morroniside is a natural product from Lonicera morrowii. | |||
TN4582 |
Moracin T
|
c-Myc; COX | Cell Cycle/Checkpoint; Immunology/Inflammation; Neuroscience |
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, including leucocyte infiltration, hyperplasia and cell proliferation; moracin treatment furthermo | |||
TN1331 |
7-O-Methyl morroniside
金银花,7-O-甲基莫诺甙 |
Others | Others |
7-O-Methyl morroniside is a natural product from Lonicera morrowii. | |||
TN6241 |
Momordicin IV
|
||
Momordicin IV 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6241,CAS号为 894412-35-2。 | |||
T6596 |
Morin monohydrate
Aurantica,桑色素.桑黄素,Morin Hydrate |
Others | Others |
Morin monohydrate(Aurantica)是一种植物源黄酮类天然产物,抗氧化作用较弱。Morin作为一种荧光螯合剂,可应用于铝物种的生成过程 | |||
TN1941 |
Momordicoside A
|
Others | Others |
Momordicoside A has the inhibition effect on PIP1B. | |||
T75646 |
Moroidin
|
Others | Others |
Moroidin是一种双环八肽,隶属于荨麻疹科环肽科,有效抑制纯化的微管蛋白聚合,表现为微管蛋白聚合抑制剂。此外,Moroidin对包括A549人肺癌细胞在内的多种癌细胞显示出细胞毒性作用,能诱导细胞凋亡。 | |||
TN4580 |
Morachalcone A
|
Tyrosinase | Proteases/Proteasome |
Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM); it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 uM. Morachalcone A exhibits neuroprotective effects on HT22-immortalized hippocampal cells agai | |||
TN1939 |
Momor-cerebroside I
|
Others | Others |
Momor-cerebroside I is a natural product from Sesamum indicum L. | |||
TN4576 |
Momordicine II
|
Others | Others |
Momordicine II may have antidiabetic activity, it significantly stimulated insulin secretion. It also can deter oviposition by L. trifolii significantly. | |||
T83000 |
Antitumor agent-89
|
||
Antitumor agent-89(Compd OTS-5)为源自天然的化合物,其活性表现为轻度抑制fMLP诱导的超氧化物生成。 | |||
T81761 |
Morusignin L
|
||
Morusignin L为一种表现出抗骨质疏松症效应的化学物质。 | |||
TN1946 |
Momordicoside L
|
Others | Others |
Momordicoside L has hypoglycaemic / antihyperglycaemic activities. | |||
TN6059 |
Demethoxyfumitremorgin C
|
||
Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and ex | |||
TN3245 |
7-O-Methylmorroniside
|
TNF | Apoptosis |
7-O-Methylmorroniside exhibits anti-inflammatory activity. | |||
T36954 |
Nemorosone
|
Others | Others |
Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nem... | |||
TN7421 |
Beta-Dimorphecolic acid (9(S)-HODE)
|
Others | Others |
Dexamethasone exhibits anti-inflammatory activity. | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00428 |
Conotoxin mr3e Protein, Conus marmoreus, Recombinant (His & KSI)
Mr3.4,Conotoxin mr3e,Mr3.7 |
Conus marmoreus | E. coli |
Conotoxin mr3e Protein, Conus marmoreus, Recombinant (His & KSI) is expressed in E. coli. | |||
TMPH-01698 |
MORC4 Protein, Human, Recombinant (His & Myc)
MORC4,Zinc finger CW-type domain protein 4,MOR<... |
Human | E. coli |
Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0. | |||
TMPH-00764 |
Trypsin-1 Protein, Gadus morhua, Recombinant (His)
Trypsin-1,Trypsin I |
Gadus morhua | E. coli |
Trypsin-1 Protein, Gadus morhua, Recombinant (His) is expressed in E. coli. | |||
TMPH-02214 |
Tomoregulin-1 Protein, Human, Recombinant (His)
TMEFF2,Tomoregulin-2,Transmembrane protein with EGF... |
Human | HEK293 Cells |
May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. | |||
TMPY-00112 |
Tomoregulin-1 Protein, Human, Recombinant (hFc)
TR-1,C9orf2,transmembrane protein with EGF-like and two foll... |
Human | HEK293 Cells |
TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. Tomoregul... | |||
TMPH-00930 |
Anamorsin Protein, Human, Recombinant (His & SUMO)
CIAPIN1,Fe-S cluster assembly protein DRE2 homolog,Cytokine-... |
Human | E. coli |
Anamorsin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa and the accession number is Q6FI81. | |||
TMPH-00762 |
Parvalbumin beta Protein, Gadus morhua, Recombinant (His & SUMO)
Parvalbumin beta |
Gadus morhua | E. coli |
In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Parvalbumin beta Protein, Gadus morhua, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.4 kDa and the accession number is Q90YK9. | |||
TMPH-02468 |
Mo-CBP3 Protein, Moringa oleifera, Recombinant (GST)
Chitin-binding protein 3 |
Moringa oleifera | E. coli |
Chitin-binding protein. Has antifungal activity against F.solani, F.oxysporum, C.musae and C.gloesporoides but not against P.oligandrum. Depending on concentration the antifungal activity can be fungistatic or fungicidal. Inhibits both spore germination and mycelial growth in F.solani at a concentration of 0.1 mg/ml. Has antifungal activity against C.krusei, C.albicans, C.tropicalis and C.parapsilosis. Has no chitinase, beta-glucanase or hemagglutinating activity. Acts as a flocculent. Mo-CBP3 P... | |||
TMPH-02466 |
Ribonuclease MC Protein, Momordica charantia, Recombinant (His & Myc)
MC1,Ribonuclease MC |
Momordica charantia | E. coli |
Ribonuclease MC Protein, Momordica charantia, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.7 kDa and the accession number is P23540. | |||
TMPH-01697 |
MORC3 Protein, Human, Recombinant (His & SUMO)
Zinc finger CW-type coiled-coil domain protein 3,MOR |
Human | E. coli |
Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs. Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. Binds RNA in vitro. May be required for influenza A transcription during viral infection. Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is ... | |||
TMPH-02467 |
Fimbrial protein Q Protein, Moraxella bovis, Recombinant (His)
Q pilin,Beta pilin,Fimbrial protein Q,tfpQ |
Moraxella bovis | E. coli |
Fimbrial protein Q Protein, Moraxella bovis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.9 kDa and the accession number is P07640. | |||
TMPH-02213 |
Tomoregulin-1 Protein, Human, Recombinant (E. coli, His)
H7365,TMEFF1,Tomoregulin-1,Transmembrane protein wi... |
Human | E. coli |
May inhibit NODAL and BMP signaling during neural patterning. May be a tumor suppressor in brain cancers. | |||
TMPY-06925 |
Gad m 1 Protein, Gadus morhua, Recombinant
|
Gadus morhua | E. coli |
Gad m 1 Protein, Gadus morhua, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.28 kDa. | |||
TMPY-04202 |
Tomoregulin-1 Protein, Mouse, Recombinant (hFc)
M7365,transmembrane protein with EGF-like and two follistati... |
Mouse | HEK293 Cells |
TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. Tomoregul... | |||
TMPH-02975 |
Wilms tumor protein homolog Protein, Mouse, Recombinant (His & Myc)
Wt1,Wilms tumor protein homolog |
Mouse | E. coli |
Wilms tumor protein homolog Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 56.7 kDa and the accession number is P22561. | |||
TMPH-00763 |
Parvalbumin beta Protein, Gadus morhua subsp. callarias, Recombinant (His)
Allergen Gad c I,Parvalbumin beta,Allergen M |
Gadus callarias | E. coli |
In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Parvalbumin beta Protein, Gadus morhua subsp. callarias, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.1 kDa and the accession number is P02622. | |||
TMPY-06883 |
Gad c 1 Protein, Gadus morhua, Recombinant
|
Gadus morhua | E. coli |
Gad c 1 Protein, Gadus morhua, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.06 kDa. | |||
TMPJ-01121 |
MORF4L2 Protein, Human, Recombinant (His)
MORF4L2,Transcription Factor-Like Protein MRGX,Prot... |
Human | E. coli |
Mortality Factor 4-Like Protein 2 (MORF4L2) is a member of the mortality factor (MORF) family. MORF4L2 localizes in the nucleus, possessing a protein kinase C phosphorylation site and a tyrosine phosphorylation site. MORF4L2 interacts with the Rb tumor suppressor and it has histone deacetylase activity which can either repress or promote the activity of the B-Myb promoter depending on the tissue. In addition, MORF4L2 is involved in cell growth, regulation, and senescence. | |||
TMPH-02312 |
Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO)
WT1,WT33,Wilms tumor protein |
Human | E. coli |
Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may b... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIH-0129 |
Bupropion Morpholinol-d8
|
||
Bupropion Morpholinol-d8 是 Bupropion Morpholinol 的氘代化合物。 |