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Targets Recommended: Microtubule Associated ADC Cytotoxin

抑制剂 & 化合物

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T4677	MMAD Monomethylauristatin D,Demethyldolastatin 10,单甲基澳瑞他汀 D,Monomethyl Dolastatin 10	Microtubule Associated; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	MMAD (Demethyldolastatin 10) 是一种有效的微管蛋白抑制剂，是抗体药物偶联物中的一种毒素有效载荷。
T18870	Vc-MMAD	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	Vc-MMAD 由 linker (Val-Cit) 和微管抑制剂 MMAD 组成。Vc-MMAD 可用于偶联抗体。
T18311	Mc-MMAD	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	Mc-MMAD, a drug-linker conjugate for antibody-drug conjugates (ADCs), incorporates the protective group maleimidocaproyl (Mc) conjugated to monomethyl auristatin D (MMAD), a potent inhibitor of tubulin.
T74075	MC-VC-PAB-MMAD	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	MC-VC-PAB-MMAD为一种抗体-活性分子偶联物，连接了微管抑制剂MMAD与可降解的ADC linker MC-VC-PAB。
T74074	OSu-Glu-VC-PAB-MMAD	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	OSu-Glu-VC-PAB-MMAD是由微管抑制剂MMAD与可降解的ADC linker OSu-Glu-VC-PAB通过一种高度特异性的连接方式构成，作为抗体-活性分子偶联物（antibody-drug conjugates, ADCs）中的关键组成部分。
T5326	Sugammadex sodium Org25969,Sugammadex (sodium),舒更葡糖钠	Others	Others
	Sugammadex sodium (Org25969) 是合成的 γ 环糊精衍生物，是一种新型的神经肌肉阻断逆转剂。
T17741	Cys-mcMMAD	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	Cys-mcMMAD is a drug-linker conjugate for ADC. MMAD is a potent tubulin inhibitor.
T5326L	Sugammadex Org-25969,Org25969,Org 25969,361LPM2T56	Others	Others
	Sugammadex is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA). Sugammadex is a modified γ-cyclodextrin, with a lipophilic core and a hydrophilic periph

化合物

MMAD

Cat.No: T4677

Synonym: Monomethylauristatin D,Demethyldolastatin 10,单甲基澳瑞他汀 D,Monomethyl Dolastatin 10

Target: Microtubule Associated, ADC Cytotoxin

Vc-MMAD

Cat.No: T18870

Synonym:

Target: Others, Drug-Linker Conjugates for ADC

Mc-MMAD

Cat.No: T18311

Synonym:

Target: Others, Drug-Linker Conjugates for ADC

MC-VC-PAB-MMAD

Cat.No: T74075

Synonym:

Target: Others, Drug-Linker Conjugates for ADC

OSu-Glu-VC-PAB-MMAD

Cat.No: T74074

Synonym:

Target: Others, Drug-Linker Conjugates for ADC

Sugammadex sodium

Cat.No: T5326

Synonym: Org25969,Sugammadex (sodium),舒更葡糖钠

Target: Others, Drug-Linker Conjugates for ADC

Sugammadex

Cat.No: T5326L

Synonym: Org-25969,Org25969,Org 25969,361LPM2T56

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T10947	D8-MMAD Monomethylauristatin D D8,Demethyldolastatin 10 D8,Monomethyl Dolastatin 10 D8	Others	Others
	D8-MMAD is a deuterated form of MMAD, which is a microtubule destroyer.