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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T71067 |
MK-1775 hemihydrate
|
Others | Others |
MK-1775 hemihydrate is a WEE1 inhibitor with potential antineoplastic sensitizing activity. | |||
T2077 |
Adavosertib
AZD1775,MK-1775,Adavosertib (MK-1775) |
Wee1 | Cell Cycle/Checkpoint |
Adavosertib (MK-1775) 是一种细胞周期调节蛋白 Wee1 的抑制剂 (IC50=5.2 nM),具有选择性。Adavosertib 具有抗肿瘤活性,可以阻滞细胞周期,抑制肿瘤细胞增殖。 | |||
T0805 |
Quinapril hydrochloride
CI-906,PD-109452-2,盐酸喹那普利,Quinapril HCl |
RAAS | Endocrinology/Hormones |
Quinapril hydrochloride (PD-109452-2) 是一种血管紧张素转化酶(ACE) 抑制剂的原药。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T71065 |
Quinapril-d5
|
||
Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapril reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats. It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations con... |