Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39545 |
MK-6884
|
Others | Others |
MK-6884, a positive allosteric modulator (PAM) of M4 muscarinic receptors, exhibits a high affinity (Ki = 0.19 nM). It is a valuable compound for the investigation of neurodegenerative diseases. Additionally, MK-6884 can be efficiently radiolabeled with carbon-11, enabling its use as a PET imaging agent. | |||
T61878 |
N-Demethyl MK-6884
|
Others | Others |
N-Demethyl MK-6884 (compound 34) is an influential allosteric modulator of the M4 mAChR, which finds applicability in Alzheimer's disease research as well as the study of other diseases influenced by the M4 mAChR [1]. |