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Search Results for " mef2d "
Targets Recommended: GSK-3 CDK JNK

2

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9138 Indirubin-3′-oxime

Indirubin-3'-monoxime

GSK-3; CDK; JNK Cell Cycle/Checkpoint; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
Indirubin-3′-oxime 是一种有效的细胞周期蛋白依赖性蛋白激酶抑制剂,是 indirubin 的合成衍生物。它可通过激活软骨细胞中的 Wnt/β-catenin 信号来促进身高增长,可能在阿尔茨海默病的神经元凋亡中发挥作用。
T5535 ERK5-IN-2

ERK MAPK
ERK5-IN-2 是具有口服活性,亚微摩尔效力,选择性ERK5抑制剂,对ERK5和ERK5 MEF2D 的IC50s 分别是 0.82 和 3 μM。它抑制肿瘤异种移植生长和碱性成纤维细胞生长因子驱动的基质胶塞血管生成。

化合物

Indirubin-3′-oxime
Cat.No: T9138
Synonym: Indirubin-3'-monoxime
Target: GSK-3, CDK, JNK
ERK5-IN-2
Cat.No: T5535
Synonym:
Target: ERK
Cat. No. Product Name Species Expression System
TMPY-03431 HDAC4 Protein, Human, Recombinant (aa 612-1084)

histone deacetylase 4,HA6116,HDAC-4,HD4,BDMR,HDAC-A,AHO3,HDA...

Human Baculovirus Insect Cells
HDAC4 (histone deacetylase 4), belongs to class II of the histone deacetylase/AcuC/APhA family. Histone Deacetylases (HDACs) are a group of enzymes closely related to sirtuins. They catalyze the removal of acetyl groups from lysine residues in histones and non-histone proteins, resulting in transcriptional repression. In general, they do not act autonomously but as components of large multiprotein complexes, such as pRb-E2F and mSin3A, that mediate important transcription regulatory pathways. Th...

重组蛋白

HDAC4 Protein, Human, Recombinant (aa 612-1084)
Cat.No: TMPY-03431
Species: Human
Expression System: Baculovirus Insect Cells
TargetMol Loading
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