Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T41225 |
MD13
|
Others | Others |
MD13 是一种巨噬细胞迁移抑制因子 (MIF) 导向的 PROTAC,Ki 值为 71 nM。MD13 可用于癌症研究。 | |||
T69525 |
MIF degrader MD13
|
Others | Others |
MIF degrader MD13 is involved in protein-protein interactions that play key roles in inflammation and cancer. Current strategies to develop small molecule modulators of MIF functions are mainly restricted to the MIF tautomerase active siteMIF degrader MD13. MD13 also exhibits antiproliferative effect in a 3D tumor spheroid model. In conclusion, we describe the first MIF-directed PROTAC (MD13) as a research tool, which also demonstrates the potential of PROTACs in cancer therapy. | |||
T41229 |
MD15
MD15 |
Others | Others |
MD15 is a negative control for MD13. |