首页 工具
登录
购物车

搜索结果

Search Results for " md "
Targets Recommended: Mdm2 NMDAR Others

313

抑制剂 & 化合物

8

天然产物

38

重组蛋白

3

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求,可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

点击图片重新获取验证码
Cat. No. Product Name Target Signaling Pathways
T3475 MD 39-AM

Others Others
MD 39-AM 的活性通过在含有激动素但不含抗细胞分裂素的培养基上 50% 的愈伤组织生长来评估。
T11980 MD-224

Mdm2; E1/E2/E3 Enzyme; PROTACs Apoptosis; PROTAC; Ubiquitination
MD-224是一种基于蛋白水解靶向嵌合体(PROTAC)概念的高效、高效的MDM2降解剂,是一类新型抗癌剂。
T5323 Toloxatone

托洛沙酮,MD 69276

MAO; Monoamine Oxidase Metabolism; Neuroscience
Toloxatone (MD 69276) 是可逆的单胺氧化酶 A (MAOA) 抑制剂,是一种抗抑郁剂。
T37041 MD-222

PROTACs PROTAC
MD-222, a pioneering, highly potent PROTAC degrader targeting MDM2, efficiently mediates the rapid degradation of MDM2 protein and activates wild-type p53 within cells, showcasing significant anticancer effects[1][2].
T68784 MD 780236

Others Others
MD 780236 is a monoamine oxidase-B inhibitor.
T68785 MD 220661

Others Others
MD 220661 is an inhibitor of semicarbazide-sensitive amine oxidase (SSAO), and a substrate of the enzyme.
T0155 Argatroban

MCI-9038,阿加曲班,MD-805,Argipidine

Thrombin Proteases/Proteasome
Argatroban (MCI-9038) 是一种选择性的凝血酶抑制剂。
T0368 Cinepazide maleate

马来酸桂哌齐特,MD-67350,Vasodistal,Brendil

Calcium Channel Membrane transporter/Ion channel; Metabolism
Cinepazide maleate (MD-67350) 是哌嗪衍生物,是一种钙通道阻滞剂,也是一种强效血管扩张剂,可用于脑血管疾病的研究,如缺血性中风和脑梗塞等。
T4231 MD2-IN-1

TLR Immunology/Inflammation
MD2-IN-1 是骨髓分化蛋白 2 (MD2) 的抑制剂,对重组人 MD2 (rhMD2) 的 KD 为 189  μM。
T7672 MD2-TLR4-IN-1

TLR Immunology/Inflammation
MD2-TLR4-IN-1 是一种骨髓分化蛋白 2/toll 样受体 4 (MD2-TLR4) 复合物抑制剂,能够抑制巨噬细胞 LPS 诱导的 TNF-α 和 IL-6 的表达,IC50值分别为 0.89 和 0.53 μM。
T26761 Befloxatone

MD 370503,MD-370,503,MD370503,MD-370503

Others Others
Befloxatone is a potent, selective and reversible inhibitor of monoamine oxidase A.
T41225 MD13

Others Others
MD13 是一种巨噬细胞迁移抑制因子 (MIF) 导向的 PROTAC,Ki 值为 71 nM。MD13 可用于癌症研究。
T25252 Cimoxatone

MD-780515,MD780515,MD 780515

Others Others
Cimoxatone is used as a Monoamine Oxidase Inhibitor.
T70569 MD-230254

Others Others
MD-230254 is an inhibitor of MAO-B.
T35800 MD001

Others Others
MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ.1 It binds to PPARα and PPARγ (Kds = 9.55 and 0.14 μM, respectively) but does not bind to PPARβ/δ at concentrations up to 500 μM. It increases transcriptional activity of PPARα and PPARγ in a cell-based luciferase reporter assay when used at a concentration of 10 μM. MD001 (10 μM) increases expression of PPARα, PPARγ, and retinoid X receptor (RXR), as well as PPARα and PPARγ target genes, in HepG2 cells. It...
T41229 MD15

MD15

Others Others
MD15 is a negative control for MD13.
T40403 Antioxidant 1024

MD 1024

Others Others
Antioxidant 1024 (MD 1024) is an antioxidant agent and metal deactivator.
T84649 CAY10398

MD 85

Others Others
CAY10398 is a compound that serves as an isoform-selective inhibitor of histone deacetylase (HDAC1).
T25503 Hisphen

Synonyms Hisfen,MD 2

Others Others
Hisphen shows antileukemic activity.
T0368L Cinepazide

Brendil,MD67350,Vasodistal,Cinepazide free base,MD-67350,MD 67350,NSC 291562

Others Others
Cinepazide is a vasodilator used for the treatment of cardiovascular, cerebrovascular, and peripheral vascular diseases. Cinepazide acts as a potentiator of adenosine A2 receptors.
T33643 Nepetalactone

MD(sub 1) 84,MDI 84

Others Others
Nepetalactone is found in the plant Nepeta parnassica and has high mosquito repellency properties.
T11852L Linaclotide acetate

MM 416775,MM416775 MD-1100 acetate,Linzess,MM-416775

Others Others
Linaclotide acetate is used as an oral guanylate cyclase C agonist linaclotide; 14 amino acid peptide for the potential treatment of constipation-predominant irritable bowel syndrome and chronic idiopathic constipation.
T22246 Argatroban Monohydrate

阿加曲班一水合物,阿加曲班

Thrombin Proteases/Proteasome
Argatroban Monohydrate 是一种 thrombin 选择性抑制剂。
T25781 MDL 101146

MDL-101146,MD 101,146,MDL101146,MDL 101,146,MDL-101,146

Others Others
MDL 101146 is an orally active neutrophil elastase inhibitor.
T20032 CI Direct Brown 2

Airedale Brown MD,Brown M,NSC 74701,Direct Brown 2,NSC-74701,NSC74701

CI Direct Brown 2 is a direct dye. It is soluble in water and ionizable to form colored anions. It also can directly dye cellulose fibers or protein fibers.
T68593 Almoxatone

Others Others
Almoxatone, also known as MD 780236, is a monoamine oxidase (MAO) inhibitor.
T70567 CGS 25462

Others Others
CGS 25462 is a neutral endopeptidase (NEP) inhibitor.
T70231 Osanetant HCl

Others Others
Osanetant HCl is the (R)-enantiomer; neurokinin-3 receptor antagonist
T74736 2MD

Others Others
2MD是一种口服活性维生素D类似物,能刺激骨膜骨形成并减少小梁骨吸收,从而恢复小梁和皮质骨的质量与强度。在非人灵长类动物研究中,2MD还可以调节(IOP)相关基因,降低眼压。
T69525 MIF degrader MD13

Others Others
MIF degrader MD13 is involved in protein-protein interactions that play key roles in inflammation and cancer. Current strategies to develop small molecule modulators of MIF functions are mainly restricted to the MIF tautomerase active siteMIF degrader MD13. MD13 also exhibits antiproliferative effect in a 3D tumor spheroid model. In conclusion, we describe the first MIF-directed PROTAC (MD13) as a research tool, which also demonstrates the potential of PROTACs in cancer therapy.
T67698 p53-Mdm2 inhibitor 4

Mdm2; p53 Apoptosis
p53-Mdm2 inhibitor 4 抑制 p53-MDM2 蛋白质-蛋白质相互作用。
T12302 OMDM-1

(Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide

Endogenous Metabolite Metabolism
OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) 是有效选择性的代谢稳定 anandamide 细胞摄取抑制剂,Ki=为2.4 μM。
T72026 p53-MDM2-IN-1

Mdm2; p53 Apoptosis
p53-MDM2-IN-1 (Example 30) 是一种 p53-MDM2/X 蛋白相互作用的抑制剂,Ki 值为 23.35 µM。p53-MDM2-IN-1 能用于抗肿瘤研究。
T1772 MDK83190

Apoptosis Activator 2

Apoptosis; Caspase Apoptosis; Proteases/Proteasome
MDK83190 (Apoptosis Activator 2) 是一种细胞凋亡激活剂,可诱导 caspase-3 激活、Apaf-1 寡聚化、PARP 切割和 DNA 片段化。
T1897 MDL-29951

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
MDL 29951 是一种新颖的 nMDA receptor 拮抗剂,能够抑制体内体外甘氨酸 ([3H]glycine) 的结合,Ki=0.14 μM。
T19765 MDK-4025

Calcium Channel Membrane transporter/Ion channel; Metabolism
MDK-4025 是锥体神经元中高压激活 (HVA) Ca2+ 电流的抑制剂。
T22565 AMD-070 hydrochloride

N-(1H-苯并咪唑-2-基甲基)-N-[(8S)-5,6,7,8-四氢-8-喹啉基]-1,4-丁二胺单盐酸盐

CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation
AMD-070 hydrochloride 是一种 CXCR4 拮抗剂,可用于抗 HIV。
T3710 XMD16-5

Tyrosinase; PPAR DNA Damage/DNA Repair; Metabolism; Proteases/Proteasome
XMD16-5 是TNK2抑制剂,对D163E 和R806Q 突变体的IC50值分别为16和77nM。
T13102 TCMDC-135051

Others Others
TCMDC-135051 是一种高选择性和有效性的蛋白激酶 PfCLK3 抑制剂,具有低的靶外毒性。TCMDC-135051 可以防止滋养体到裂殖体的转变,破坏转录并减少向蚊子载体的传播。TCMDC-135051 具有抗寄生虫活性 (EC50=320 nM)。
T7766 Remdesivir

瑞德西韦,GS-5734

SARS-CoV; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Remdesivir (GS-5734) 是一种核苷类似物,一种广谱的抗病毒化合物,通过抑制病毒的 RNA 依赖性 RNA 聚合酶发挥活性。Remdesivir 对埃博拉病毒、SARS 病毒、MERS病毒等均有活性,对 COVID-19 有潜在治疗价值。
T61270 MDH1-IN-1

Others Others
MDH1-IN-1 (5i) 是一种有效的 MDH1 抑制剂,对 MDH1 的 IC50 为 6.79 μM,对 MDH2 的 IC50 为 >40 μM。MDH1-IN-1 具有潜在的抗癌活性,可用于研究与免疫系统相关的疾病。
T73718 MDCG sodium

NOX 100 sodium,N-methyl-N-dithiocarboxyglucamine sodium

Endogenous Metabolite Metabolism
MDCG sodium (N-methyl-N-dithiocarboxyglucamine sodium) 是一种金属螯合剂,可促进Cd的胆道排泄。
T25373 EMD57439

EMD-57439,EMD 57439

PDE Metabolism
EMD57439是一种选择性的PDE-III 抑制剂,对c-AMP 浓度没有显示出明显的增长 且在Ca(50)中产生的变化很小。
T1842 XMD17-109

XMD17 109,ERK5-IN-1

ERK MAPK
XMD17-109 (ERK5-IN-1) 是一种特异性的ERK-5抑制剂,在 HEK293 细胞系中的EC50为 4.2 μM。
T72662 NMDAR/TRPM4-IN-2

ERK; TRP/TRPV Channel; NMDAR; iGluR MAPK; Membrane transporter/Ion channel; Neuroscience
NMDAR/TRPM4-IN-2 是一种有效的 NMDAR/TRPM4 相互作用界面抑制剂。NMDAR/TRPM4-IN-2 保护小鼠免受 MCAO 诱导的脑损伤和 NMDA 诱导的视网膜神经节细胞丢失。NMDAR/TRPM4-IN-2 具有神经保护活性, 可预防 NMDA 诱导的海马神经元细胞死亡和线粒体功能障碍,其 IC50 值为 2.1 μM。
T22359 MDL 100009

5-HT Receptor GPCR/G Protein; Neuroscience
MDL 100009 是 MDL 100151 的 S-对映体和 MDL 100907 的相反对映体,是 5-HT2A 的选择性拮抗剂。
T22965 MDL 72527

N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine dihydrochloride

Others Others
MDL 72527 (N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine dihydrochloride) 是一种多胺氧化酶 (POA) 抑制剂
T7208 AMD 3465 hexahydrobromide

GENZ-644494 (hexahydrobromide)

HIV Protease; CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) 是一种 CXCR4受体拮抗剂,具有潜在的抗癌和抗 HIV 活性。
T62839 Dalzanemdor

SAGE-718

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
Dalzanemdor (SAGE-718) 是 NMDA 受体阳性变构调节剂,可用于研究亨廷顿舞蹈病、阿尔茨海默病和认知功能障碍。
T12306 OMDM-5

Cannabinoid Receptor; Endogenous Metabolite; TRP/TRPV Channel GPCR/G Protein; Membrane transporter/Ion channel; Metabolism
OMDM-5 是有效的、选择性的anandamide 细胞摄取抑制剂,Ki 为 4.8 μM。它是VR1 (TRPV1)激动剂,EC50为 75 nM,显示出对大麻素 1 型受体 (CB1) 的弱配体活性 (Ki=4.9 μM)。

化合物

MD 39-AM
Cat.No: T3475
Synonym:
Target: Others
MD-224
Cat.No: T11980
Synonym:
Target: Mdm2, E1/E2/E3 Enzyme, PROTACs
Toloxatone
Cat.No: T5323
Synonym: 托洛沙酮,MD 69276
Target: MAO, Monoamine Oxidase
MD-222
Cat.No: T37041
Synonym:
Target: PROTACs
MD 780236
Cat.No: T68784
Synonym:
Target: Others
MD 220661
Cat.No: T68785
Synonym:
Target: Others
Argatroban
Cat.No: T0155
Synonym: MCI-9038,阿加曲班,MD-805,Argipidine
Target: Thrombin
Cinepazide maleate
Cat.No: T0368
Synonym: 马来酸桂哌齐特,MD-67350,Vasodistal,Brendil
Target: Calcium Channel
MD2-IN-1
Cat.No: T4231
Synonym:
Target: TLR
MD2-TLR4-IN-1
Cat.No: T7672
Synonym:
Target: TLR
Befloxatone
Cat.No: T26761
Synonym: MD 370503,MD-370,503,MD370503,MD-370503
Target: Others
MD13
Cat.No: T41225
Synonym:
Target: Others
Cimoxatone
Cat.No: T25252
Synonym: MD-780515,MD780515,MD 780515
Target: Others
MD-230254
Cat.No: T70569
Synonym:
Target: Others
MD001
Cat.No: T35800
Synonym:
Target: Others
MD15
Cat.No: T41229
Synonym: MD15
Target: Others
Antioxidant 1024
Cat.No: T40403
Synonym: MD 1024
Target: Others
CAY10398
Cat.No: T84649
Synonym: MD 85
Target: Others
Hisphen
Cat.No: T25503
Synonym: Synonyms Hisfen,MD 2
Target: Others
Cinepazide
Cat.No: T0368L
Synonym: Brendil,MD67350,Vasodistal,Cinepazide free base,MD-67350,MD 67350,NSC 291562
Target: Others
Nepetalactone
Cat.No: T33643
Synonym: MD(sub 1) 84,MDI 84
Target: Others
Linaclotide acetate
Cat.No: T11852L
Synonym: MM 416775,MM416775 MD-1100 acetate,Linzess,MM-416775
Target: Others
Argatroban Monohydrate
Cat.No: T22246
Synonym: 阿加曲班一水合物,阿加曲班
Target: Thrombin
MDL 101146
Cat.No: T25781
Synonym: MDL-101146,MD 101,146,MDL101146,MDL 101,146,MDL-101,146
Target: Others
CI Direct Brown 2
Cat.No: T20032
Synonym: Airedale Brown MD,Brown M,NSC 74701,Direct Brown 2,NSC-74701,NSC74701
Target:
Almoxatone
Cat.No: T68593
Synonym:
Target: Others
CGS 25462
Cat.No: T70567
Synonym:
Target: Others
Osanetant HCl
Cat.No: T70231
Synonym:
Target: Others
2MD
Cat.No: T74736
Synonym:
Target: Others
MIF degrader MD13
Cat.No: T69525
Synonym:
Target: Others
p53-Mdm2 inhibitor 4
Cat.No: T67698
Synonym:
Target: Mdm2, p53
OMDM-1
Cat.No: T12302
Synonym: (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide
Target: Endogenous Metabolite
p53-MDM2-IN-1
Cat.No: T72026
Synonym:
Target: Mdm2, p53
MDK83190
Cat.No: T1772
Synonym: Apoptosis Activator 2
Target: Apoptosis, Caspase
MDL-29951
Cat.No: T1897
Synonym:
Target: NMDAR, iGluR
MDK-4025
Cat.No: T19765
Synonym:
Target: Calcium Channel
AMD-070 hydrochloride
Cat.No: T22565
Synonym: N-(1H-苯并咪唑-2-基甲基)-N-[(8S)-5,6,7,8-四氢-8-喹啉基]-1,4-丁二胺单盐酸盐
Target: CXCR
XMD16-5
Cat.No: T3710
Synonym:
Target: Tyrosinase, PPAR
TCMDC-135051
Cat.No: T13102
Synonym:
Target: Others
Remdesivir
Cat.No: T7766
Synonym: 瑞德西韦,GS-5734
Target: SARS-CoV, DNA/RNA Synthesis
MDH1-IN-1
Cat.No: T61270
Synonym:
Target: Others
MDCG sodium
Cat.No: T73718
Synonym: NOX 100 sodium,N-methyl-N-dithiocarboxyglucamine sodium
Target: Endogenous Metabolite
EMD57439
Cat.No: T25373
Synonym: EMD-57439,EMD 57439
Target: PDE
XMD17-109
Cat.No: T1842
Synonym: XMD17 109,ERK5-IN-1
Target: ERK
NMDAR/TRPM4-IN-2
Cat.No: T72662
Synonym:
Target: ERK, TRP/TRPV Channel, NMDAR, iGluR
MDL 100009
Cat.No: T22359
Synonym:
Target: 5-HT Receptor
MDL 72527
Cat.No: T22965
Synonym: N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine dihydrochloride
Target: Others
AMD 3465 hexahydrobromide
Cat.No: T7208
Synonym: GENZ-644494 (hexahydrobromide)
Target: HIV Protease, CXCR
Dalzanemdor
Cat.No: T62839
Synonym: SAGE-718
Target: NMDAR, iGluR
OMDM-5
Cat.No: T12306
Synonym:
Target: Cannabinoid Receptor, Endogenous Metabolite, TRP/TRPV Channel
Cat. No. Product Name Target Signaling Pathways
T5S0045 Isofraxidin

6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶

MMP; ERK; p38 MAPK; TLR; COX Immunology/Inflammation; MAPK; Neuroscience; Proteases/Proteasome
Isofraxidin (Phytodolor) 是来自刺五加的香豆素成分,抑制MMP-7表达和人肝癌细胞侵袭。它作用于肝癌细胞,抑制ERK1/2磷酸化。它减弱iNOS 和COX-2表达,还抑制TLR4/髓样分化蛋白 2 复合物的形成。
T6608 NMDA

N-甲基-D-天冬氨酸,N-Methyl-D-aspartic acid

Endogenous Metabolite; NMDAR; iGluR Membrane transporter/Ion channel; Metabolism; Neuroscience
NMDA (N-Methyl-D-aspartic acid) 是一种氨基酸,作为 D-异构体,是谷氨酸受体的 NMDA 受体亚型的定义激动剂。
T34611 Semduramicin

UK 61,689,Aviax,UK-61,689,UK61,689

Others Others
Semduramicin is a carboxylic acid ionophore for management of chicken coccidiosis.
T34611L Semduramicin sodium

UK-61,689-2,UK 61,689-2,UK 61689-2,UK-61689-2,UK61689-2

Others Others
Semduramicin sodium is a carboxylic acid ionophore for management of chicken coccidiosis.
TN7520 Circumdatin A

Others Others
Circumdatin A, a benzodiazepine alkaloid derived from the fungus A. ochraceus, is a fungal metabolite.
TQ0205 Procyanidin B1

原花青素B1,原花青素 B1

TLR Immunology/Inflammation
Procyanidin B1 是水果中常见的多酚类黄酮,能够与TLR4/MD-2复合体结合,具有抗炎活性。
T5S0167 Atractylenolide I

白术内酯 I,白术内酯I;苍术内酯I

IL Receptor; TNF; TLR; JAK; STAT Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells
Atractylenolide I 是从白术根中得到的一种倍半萜烯,具有神经保护、抗过敏、抗炎和抗癌等多种生物活性。它是一种TLR4拮抗剂,在 A375 细胞中,能够降低JAK2和STAT3的磷酸化水平。
TMA1944 Protopine hydrochloride

EGFR; cAMP Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Protopine has antiplatelet effects,which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracellular calcium concentration.Protopine seems to inhibit the heterotypic cell adhesion between MD

天然产物

Isofraxidin
Cat.No: T5S0045
Synonym: 6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶
Target: MMP, ERK, p38 MAPK, TLR, COX
NMDA
Cat.No: T6608
Synonym: N-甲基-D-天冬氨酸,N-Methyl-D-aspartic acid
Target: Endogenous Metabolite, NMDAR, iGluR
Semduramicin
Cat.No: T34611
Synonym: UK 61,689,Aviax,UK-61,689,UK61,689
Target: Others
Semduramicin sodium
Cat.No: T34611L
Synonym: UK-61,689-2,UK 61,689-2,UK 61689-2,UK-61689-2,UK61689-2
Target: Others
Circumdatin A
Cat.No: TN7520
Synonym:
Target: Others
Procyanidin B1
Cat.No: TQ0205
Synonym: 原花青素B1,原花青素 B1
Target: TLR
Atractylenolide I
Cat.No: T5S0167
Synonym: 白术内酯 I,白术内酯I;苍术内酯I
Target: IL Receptor, TNF, TLR, JAK, STAT
Protopine hydrochloride
Cat.No: TMA1944
Synonym:
Target: EGFR, cAMP
Cat. No. Product Name Species Expression System
TMPY-00878 MD1 Protein, Mouse, Recombinant (His)

lymphocyte antigen 86,MD-1,MD1

Mouse HEK293 Cells
MD1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is O88188.
TMPK-00632 MD2/LY96 Protein, Cynomolgus, Recombinant (His)

ESOP-1,LY96,Lymphocyte antigen 96,ESOP1,MD-2

Cynomolgus E. coli
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 17.97 kDa and the accession number is B3Y6B0.
TMPY-03188 MD1 Protein, Human, Recombinant (hFc)

MMD-1,lymphocyte antigen 86,MD-1,dJ80N2.1,...

Human HEK293 Cells
MD1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is O95711.
TMPY-03999 MD2/LY96 Protein, Mouse, Recombinant (hFc)

lymphocyte antigen 96,ESOP-1,MD2,MD-2

Mouse HEK293 Cells
LY96 (Lymphocyte Antigen 96, also known as ESOP-1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a protein that associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccharide (LPS), thus providing a link between the receptor and LPS signaling. LY-96 also cooperates with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. It enhances the TLR4-dependent activa...
TMPK-01242 MD2/LY96 Protein, Human, Recombinant (His)

MD-2,Ly-96,ESOP-1,Lymphocyte antigen 96,LY96,ESOP1

Human E. coli
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.07 kDa and the accession number is Q9Y6Y9-1.
TMPH-00002 PSMD3 Protein, Human, Recombinant (His)

PSMD3,26S proteasome regulatory subunit S3,26S prot...

Human P. pastoris (Yeast)
PSMD3 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 63 kDa; 70 kDa, reducing conditions and the accession number is O43242.
TMPY-05581 TIM-4/TIMD4 Protein, Human, Recombinant (His), Biotinylated

T-cell immunoglobulin and mucin domain containing 4,SMUCKLER...

Human HEK293 Cells
TIM-4/TIMD4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.7 kDa and the accession number is AAH08988.1.
TMPY-01375 TIM-4/TIMD4 Protein, Mouse, Recombinant (His)

T-cell immunoglobulin and mucin domain containing 4,TIM-4,Ti...

Mouse HEK293 Cells
TIM-4/TIMD4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.3 kDa and the accession number is Q6U7R4.
TMPY-00305 MDC Protein, Mouse, Recombinant (His)

DCBCK,MDC,ABCD-1,Scya22,chemokine (C-C motif) ligan...

Mouse E. coli
MDC Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.9 kDa and the accession number is O88430.
TMPJ-00832 Granzyme D/GZMD Protein, Mouse, Recombinant (His)

Granzyme D,Gzmd

Mouse HEK293 Cells
Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, but the function of granzyme D is unknown. Previous studies reported that granzyme D is developmentally regulated during pregnancy together with granzymes E, F, and G in granulated metrial gland cells and is upregulated by IL-2 and IL-15. Granzyme D was also suggested to have a ro...
TMPH-01125 COMMD4 Protein, Human, Recombinant (GST)

COMM domain-containing protein 4,COMMD4

Human E. coli
COMMD4 Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPH-00161 MDH Protein, Bacillus methanolicus, Recombinant (His)

Type 3 alcohol dehydrogenase,mdh,NAD-dependent meth...

Bacillus methanolicus P. pastoris (Yeast)
Catalyzes the oxidation of methanol to yield formaldehyde. It possesses a NADH-dependent formaldehyde reductase activity and cannot use NADP. MDH Protein, Bacillus methanolicus, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 42.4 kDa and the accession number is P31005.
TMPY-01620 MDGA2 Protein, Mouse, Recombinant (His)

6720489L24Rik,Adp,MAM domain containing glycosylphosphatidyl...

Mouse HEK293 Cells
MAM domain-containing glycosylphosphatidylinositol anchor protein 2, also known as MAM domain-containing protein 1, MDGA2, and MAMDC1, is a cell membrane protein that contains six Ig-like (immunoglobulin-like) domains and one MAM domain. Analyses of the full-length coding region of MDGA1 and MDGA2 indicate that they encode proteins that comprise a novel subgroup of the Ig superfamily and have a unique structural organization consisting of six immunoglobulin (Ig)-like domains followed by a single...
TMPY-03613 COMMD8 Protein, Human, Recombinant (His)

COMM domain containing 8

Human E. coli
COMMD8 is a member of the COMMD family. Members of this family are a group of evolutionary conserved proteins that share a common COMM domain at the extreme C-terminus, which provides an interface for protein-protein interactions. Most COMMD proteins play a role in the regulation of NF˚B and, despite their similarities, seem to function in unique and non-redundant pathways. COMMD proteins may also play a role in the function of epithelial sodium channels, cell proliferation, copper homeostasis a...
TMPY-02756 MDC Protein, Human, Recombinant (His)

A-152E5.1,MDC,ABCD-1,SCYA22,STCP-1,DC/B-CK,chemokin...

Human E. coli
MDC Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.7 kDa and the accession number is O00626.
TMPY-01125 MDMX Protein, Human, Recombinant (His)

MRP1,MDM4, p53 regulator,HDMX,MDMX

Human E. coli
MDM4 (MDM4 Regulator Of P53, also known as MDMX) is a Protein Coding gene. This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus and shows structural similarity to p53-binding protein MDM2. MDM4 is a promising target for cancer therapy, as it is undetectable in most normal adult tissues but often upregulated in cancer cells to dampen p53 tumor-suppressor function. MDM4, an essential negative regulator of the P53 tumor ...
TMPK-01205 MDL-1/CLEC5A Protein, Human, Recombinant (hFc)

DAP12-associating lectin 1,MDL-1,MDL1,CLEC...

Human HEK293 Cells
MDL-1/CLEC5A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 46 kDa and the accession number is Q9NY25-1.
TMPH-01127 COMMD5 Protein, Human, Recombinant (His)

Hypertension-related calcium-regulated gene protein,COMM dom...

Human E. coli
COMMD5 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-00849 PSMD14 Protein, Human, Recombinant (His & MBP)

26S proteasome non-ATPase regulatory subunit 14,PSMD

Human Baculovirus Insect Cells
PSMD14 Protein, Human, Recombinant (His & MBP) is expressed in Baculovirus insect cells with N-MBP and C-6xHis tag. The predicted molecular weight is 79.2 kDa and the accession number is O00487.
TMPY-03505 COMMD9 Protein, Human, Recombinant (His)

HSPC166,COMM domain containing 9

Human E. coli
COMMD9 is a COMM domain-containing or COMMD protein. COMMD family is comprised of ten members which are widely conserved throughout evolution and share certain functional properties. They represent a recently discovered set of evolutionarily conserved factors characterized by the presence of a defining carboxy-terminal motif. COMMD protein functions in the control of the transcription factor NFkappaB. NFkappaB plays a critical role in a number of homeostatic processes in multicellular orga...
TMPY-02124 TIM-4/TIMD4 Protein, Human, Recombinant (His)

SMUCKLER,T-cell immunoglobulin and mucin domain containing 4...

Human HEK293 Cells
TIM-4/TIMD4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.7 kDa and the accession number is AAH08988.1.
TMPY-02599 MDH1 Protein, Rat, Recombinant (His)

malate dehydrogenase 1, NAD (soluble)

Rat E. coli
Malate dehydrogenases 1(MDH1 / MDHA) is a soluble form of malate dehydrogenases. Malate dehydrogenases (MDH) is a group of multimeric enzymes consisting of identical subunits usually organized as either dimer or tetramers with subunit molecular weights of 30-35 kDa. MDH has been isolated from different sources including archaea, eubacteria, fungi, plants, and mammals. MDH catalyzes the NAD/NADH-dependent interconversion of the substrates malate and oxaloacetate. This reaction plays a key part in...
TMPK-01141 TIM-4/TIMD4 Protein, Human, Recombinant (aa 25-314, His)

TIMD-4,TIMD4,TIM-4,TIM4

Human HEK293 Cells
Tim4 is a transmembrane protein as the phosphatidylserine (PS) receptor, known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed highly in macrophages, and macrophage Tim-4 inhibits inflammation under various conditions of immune activation. TIM-4/TIMD4 Protein, Human, Recombinant (aa 25-314, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 32.43 kDa and the accession number is Q96H15-1.
TMPK-01272 TIM-4/TIMD4 Protein, Cynomolgus, Recombinant (His)

TIMD4,TIMD-4,TIM-4

Cynomolgus HEK293 Cells
Tim4 is a transmembrane protein as the phosphatidylserine (PS) receptor, known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed highly in macrophages, and macrophage Tim-4 inhibits inflammation under various conditions of immune activation. TIM-4/TIMD4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 31.55 kDa and the accession number is XP_005558436.2.
TMPK-01218 MDL-1/CLEC5A Protein, Mouse, Recombinant (hFc)

MDL1,DAP12-associating lectin 1,MDL-1,CLEC...

Mouse HEK293 Cells
MDL-1/CLEC5A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 46.2 kDa and the accession number is Q9R007-1.
TMPH-03139 MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO)

Chloroquine resistance protein,MDR1,Multidrug resis...

Plasmodium falciparum E. coli
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.2 kDa and the accession number is P13568.
TMPH-00162 MDH Protein, Bacillus methanolicus, Recombinant (His & Myc & SUMO)

NAD-dependent methanol dehydrogenase,Type 3 alcohol dehydrog...

Bacillus methanolicus E. coli
Catalyzes the oxidation of methanol to yield formaldehyde. It possesses a NADH-dependent formaldehyde reductase activity and cannot use NADP. MDH Protein, Bacillus methanolicus, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 59.9 kDa and the accession number is P31005.
TMPY-04668 Influenza A H3N2 (A/Philippines/472/2002) (MDCK) Hemagglutinin/HA1 Protein (His)

Harvey rat sarcoma viral oncogene homolog

H3N2 HEK293 Cells
Influenza A H3N2 (A/Philippines/472/2002) (MDCK) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.9 kDa and the accession number is A0A097PF18.
TMPJ-00955 MDH1 Protein, Human, Recombinant (His)

Cytosolic Malate Dehydrogenase,MDH1,MDHA,D...

Human E. coli
Malate Dehydrogenase, Cytoplasmic (MDH1) is an enzyme which belongs to the MDH Type 2 sub-family of LDH/MDH superfamily. MDH1 is involved in the Citric Acid Cycle that catalyzes the conversion of Malate into Oxaloacetate (using NAD+) and vice versa. MDH1 should not be confused with Malic Enzyme, which catalyzes the conversion of Malate to Pyruvate, producing NADPH. MDH1 also participates in Gluconeogenesis, the synthesis of Glucose from smaller molecules. Pyruvate in the mitochondria is acted up...
TMPJ-00665 ADAMDEC1 Protein, Human, Recombinant (His)

a disintegrin and metalloproteinase domain-like protein decy...

Human HEK293 Cells
ADAM DEC1 protein is expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. ADAM DEC1 is induced during DC maturation and up-regulated in response to T-cell signals. It may play an important role in the control of the immune response and during pregnancy.
TMPH-02493 ADAMDEC1 Protein, Mouse, Recombinant (His)

A disintegrin and metalloproteinase domain-like protein decy...

Mouse E. coli
May play an important role in the control of the immune response and during pregnancy. ADAMDEC1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.9 kDa and the accession number is Q9R0X2.
TMPH-03269 COMMD5 Protein, Rat, Recombinant (His & Myc)

COMM domain-containing protein 5,COMMD5,Hypertensio...

Rat E. coli
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.
TMPH-02630 MDM2 Protein, Mouse, Recombinant (His)

E3 ubiquitin-protein ligase Mdm2,RING-type E3 ubiqu...

Mouse E. coli
MDM2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.6 kDa and the accession number is P23804.
TMPJ-01205 MDP1 Protein, Human, Recombinant (His)

Magnesium-dependent phosphatase 1,MDP-1,EC=3.1.3.48

Human HEK293 Cells
MDP1, which is short for nesium-dependent phosphatase 1, is a 176 aa. protein. It has 3 forms by different alternative splicing. This protein belongs to the HAD-like hydrolase superfamily, and usually takes its function with Magnesium. It can be inhibited by vanadate and zinc, and slightly by calcium. MDP1 is a Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.
TMPJ-00956 MDH2 Protein, Human, Recombinant (His)

MDH2,Malate dehydrogenase,mitochondrial

Human HEK293 Cells
Malate dehydrogenase, mitochondrial is a 338 amino acids protein that belongs to the LDH/MDH superfamily. MDH type 1 family. MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highly expressed in the adrenal system, small intestine, heart and panc...
TMPH-01126 COMMD5 Protein, Human, Recombinant (His & Myc)

Hypertension-related calcium-regulated gene protein,HCaRG,CO...

Human Baculovirus Insect Cells
COMMD5 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPJ-00527 SP-D Protein, Human, Recombinant (His)

Lung Surfactant Protein D,SFTP4,COLEC7,SFTPD,PSP-D,SP-D,Pulm...

Human HEK293 Cells
Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognition domain (CRD), a structure that places it in a subset of pattern recognition proteins termed defense collagens. SP-D is constitutively secreted by alveolar lining cells and epithelium associated with tubular structures and induced in cardiac smooth muscle and endothelial cells. ...
TMPY-02122 IFNGR2 Protein, Mouse, Recombinant (His)

interferon γ receptor 2 (interferon γ transducer 1),interfer...

Mouse HEK293 Cells
Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2. IFNGR2 is a component of the IFNgamma receptor complex al...

重组蛋白

MD1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00878
Species: Mouse
Expression System: HEK293 Cells
MD2/LY96 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00632
Species: Cynomolgus
Expression System: E. coli
MD1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03188
Species: Human
Expression System: HEK293 Cells
MD2/LY96 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03999
Species: Mouse
Expression System: HEK293 Cells
MD2/LY96 Protein, Human, Recombinant (His)
Cat.No: TMPK-01242
Species: Human
Expression System: E. coli
PSMD3 Protein, Human, Recombinant (His)
Cat.No: TMPH-00002
Species: Human
Expression System: P. pastoris (Yeast)
TIM-4/TIMD4 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05581
Species: Human
Expression System: HEK293 Cells
TIM-4/TIMD4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01375
Species: Mouse
Expression System: HEK293 Cells
MDC Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00305
Species: Mouse
Expression System: E. coli
Granzyme D/GZMD Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00832
Species: Mouse
Expression System: HEK293 Cells
COMMD4 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01125
Species: Human
Expression System: E. coli
MDH Protein, Bacillus methanolicus, Recombinant (His)
Cat.No: TMPH-00161
Species: Bacillus methanolicus
Expression System: P. pastoris (Yeast)
MDGA2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01620
Species: Mouse
Expression System: HEK293 Cells
COMMD8 Protein, Human, Recombinant (His)
Cat.No: TMPY-03613
Species: Human
Expression System: E. coli
MDC Protein, Human, Recombinant (His)
Cat.No: TMPY-02756
Species: Human
Expression System: E. coli
MDMX Protein, Human, Recombinant (His)
Cat.No: TMPY-01125
Species: Human
Expression System: E. coli
MDL-1/CLEC5A Protein, Human, Recombinant (hFc)
Cat.No: TMPK-01205
Species: Human
Expression System: HEK293 Cells
COMMD5 Protein, Human, Recombinant (His)
Cat.No: TMPH-01127
Species: Human
Expression System: E. coli
PSMD14 Protein, Human, Recombinant (His & MBP)
Cat.No: TMPH-00849
Species: Human
Expression System: Baculovirus Insect Cells
COMMD9 Protein, Human, Recombinant (His)
Cat.No: TMPY-03505
Species: Human
Expression System: E. coli
TIM-4/TIMD4 Protein, Human, Recombinant (His)
Cat.No: TMPY-02124
Species: Human
Expression System: HEK293 Cells
MDH1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02599
Species: Rat
Expression System: E. coli
TIM-4/TIMD4 Protein, Human, Recombinant (aa 25-314, His)
Cat.No: TMPK-01141
Species: Human
Expression System: HEK293 Cells
TIM-4/TIMD4 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01272
Species: Cynomolgus
Expression System: HEK293 Cells
MDL-1/CLEC5A Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01218
Species: Mouse
Expression System: HEK293 Cells
MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO)
Cat.No: TMPH-03139
Species: Plasmodium falciparum
Expression System: E. coli
MDH Protein, Bacillus methanolicus, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-00162
Species: Bacillus methanolicus
Expression System: E. coli
Influenza A H3N2 (A/Philippines/472/2002) (MDCK) Hemagglutinin/HA1 Protein (His)
Cat.No: TMPY-04668
Species: H3N2
Expression System: HEK293 Cells
MDH1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00955
Species: Human
Expression System: E. coli
ADAMDEC1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00665
Species: Human
Expression System: HEK293 Cells
ADAMDEC1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02493
Species: Mouse
Expression System: E. coli
COMMD5 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03269
Species: Rat
Expression System: E. coli
MDM2 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02630
Species: Mouse
Expression System: E. coli
MDP1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01205
Species: Human
Expression System: HEK293 Cells
MDH2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00956
Species: Human
Expression System: HEK293 Cells
COMMD5 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01126
Species: Human
Expression System: Baculovirus Insect Cells
SP-D Protein, Human, Recombinant (His)
Cat.No: TMPJ-00527
Species: Human
Expression System: HEK293 Cells
IFNGR2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02122
Species: Mouse
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
TMIH-0491 Remdesivir Impurity 5-d5

Remdesivir Impurity 5-d5 是 Remdesivir Impurity 5 的氘代化合物。
T12702 Remdesivir-D5

GS-5734-D5

Others Others
Remdesivir-D5 is a deuterium labeled Remdesivir. Remdesivir is a nucleoside analogue, with effective antiviral activity.
TMIJ-0254 Remdesivir-d4

Remdesivir-d4 是 Remdesivir 的氘代化合物。Remdesivir 的 CAS 号为 1809249-37-3。Remdesivir是一种核苷类似物,具有抗病毒活性,在 HAE 细胞中,对SARS-CoV和MERS-CoV的EC50值为 74 nM,有潜力用于 2019-nCoV (COVID-19) 研究。

同位素标记化合物

Remdesivir Impurity 5-d5
Cat.No: TMIH-0491
Synonym:
Target:
Remdesivir-D5
Cat.No: T12702
Synonym: GS-5734-D5
Target: Others
Remdesivir-d4
Cat.No: TMIJ-0254
Synonym:
Target:
共313条,每页50条 1 2 3 4 5 6 7
TargetMol Loading
联系我们
400-820-0310

上海市静安区江场三路238号8楼