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Search Results for " mcf-7 cell "

Targets Recommended: Epigenetic Reader Domain

87

抑制剂 & 化合物

67

天然产物

10

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9541	CTB Cholera Toxin B subunit	Epigenetic Reader Domain	Chromatin/Epigenetic
	CTB (Cholera Toxin B subunit) 是一种 p300 组蛋白乙酰转移酶的激活剂，可诱导 MCF-7 细胞凋亡。
T15578	Indotecan NSC-724998,LMP-400	Topoisomerase	DNA Damage/DNA Repair
	Indotecan (LMP-400) 是一种有效的拓扑异构酶 1 抑制剂，对 P388、HCT116和MCF-7 细胞系的IC50值分别为 300、1200和560 nM。
T77718	FAK-IN-10	FAK	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	FAK-IN-10 是一种 FAK 的抑制剂（IC50:76.3 μM)。FAK-IN-10 z MCF-7 和 A431 细胞系中显示出抗肿瘤活性，IC50 分别为 4.23 和 0.78 μM 。
T36970	STD1T	DUB	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
	STD1T 是一种具有选择性和有效性的脱泛素酶 USP2a 抑制剂，具有潜在的抗癌活性，可降低 HCT116 结肠和 MCF-7 乳腺癌细胞中的细胞周期蛋白 D1 蛋白水平。
T21804	GW 610	Others	Others
	GW 610 是一种抗肿瘤剂，能够选择性作用于肺癌、结肠癌和乳腺癌细胞系，具有抗癌活性。
T83627	Pim-1 kinase inhibitor 8	Pim; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling
	Pim-1 kinase inhibitor 8 是一种高效的 Pim-1 kinase 抑制剂，具有抗癌活性，可有效抑制细胞迁移。Pim-1 kinase inhibitor 8 对 MCF-7 和 HepG2 细胞有细胞毒性，是研究乳腺癌的候选化合物。
T5350	JG-98 JG98,JG 98	Apoptosis; HSP	Apoptosis; Cytoskeletal Signaling; Metabolism
	JG-98 是一种热休克蛋白 70 (Hsp70)变构抑制剂，可与 Hsp70 上的保守位点紧密结合，打断 Hsp70-Bag3 相互作用。它影响癌细胞和肿瘤相关巨噬细胞，具有抗癌活性。
T7057	Methylstat	Histone Demethylase; Others	Chromatin/Epigenetic; Others
	Methylstat 是一种含有 Jumonji C 结构域的组蛋白去甲基化酶 (JMJD) 抑制剂的甲酯前药，具有良好的细胞渗透性。在体外试验中，methylstat 的游离酸可抑制 JMJD2A、JMJD2C、JMJD2E、PHF8 和 JMJD3，IC50 值分别约为 4.3、3.4、5.9、10 和 43 µM。 Methylstat 抑制 JMJD2C 敏感的食管癌细胞系 KYSE150 的生长，GI50 为 5.1 µM，而 methylstat 的游离酸在高达 100 µM 时不抑制细胞生长。 Methylstat 以浓度依赖性方式在多个位点诱导组蛋白高甲基化（KYSE150 细胞中 H3K4me3 和 H3K9me3 的 EC50 = 10.3 和 8.6 µM，MCF-7 细胞中的 EC50 分别为 6.7 和 6.3 µM）。
T31988	Govaniadine	Others	Others
	Govaniadine is a natural potent inducer of apoptosis in MCF-7 cell lines.
T10695	CB1151	Others	Others
	CB1151 is a 20-epi analogue of 1,25 dihydroxyvitamin D3 with anti-tumor effects. It inhibits MCF-7 cell growth (IC50: 0.82 nM).
T79109	Estrogen receptor modulator 8	Estrogen Receptor/ERR	Endocrinology/Hormones
	Estrogen receptor modulator8 (compound 4) 为一口服活性化合物，作用为抑制雌激素受体/ERR α（IC50=0.437 nM，MCF-7 细胞）。此化合物能有效抑制MCF-7细胞的增殖，其IC50值仅为0.1 nM。
T63676	Bcl-2-IN-6	Others	Others
	Bcl-2-IN-6 是 Bcl-2 (b 细胞淋巴瘤-2) 的有效抑制剂，可下调 Bcl-2 的表达，并提高 p53、Bax、caspase-7 mRNA 的表达。Bcl-2-IN-7 能够诱导乳腺癌 MCF-7 细胞周期阻滞和凋亡。Bcl-2-IN-7 能够作用于 MCF-7 细胞 (IC50: 20.91 μM)、LoVo 细胞 (IC50: 22.30 μM)、HepG2 细胞 (IC50: 42.29 μM) 和 A549 细胞 (IC50: 48.00 μM) 均显示出良好的抗肿瘤效果。
T83874	S-72	Others	Others
	S-72是一种微管聚合抑制剂，以1, 3, 10 µM的浓度在无细胞测定中抑制微管聚合，并在MCF-7和耐紫杉醇的MCF-7/T乳腺癌细胞中降低细胞活性（IC50分别为15.64和26.32 nM）。50 nM浓度的S-72能抑制MCF-7和MCF-7/T细胞的迁移和侵袭，并减少划痕实验中的伤口闭合百分比。100 nM的S-72在MCF-7/T细胞中诱导G2/M期的细胞周期阻滞以及凋亡，并在同一浓度下抑制这些细胞中干扰素基因激活剂（STING）的激活。以每天15 mg/kg的剂量，S-72抑制了耐紫杉醇的MCF-7/T和MX-1/T小鼠异种移植模型中的肿瘤生长。
T79728	EGFR/CDK2-IN-3	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR/CDK2-IN-3（compound 4b）是一种针对EGFR与CDK-2的双重抑制剂，分别具有71.7 nM和113.7 nM的IC50s。该化合物在MCF-7细胞中能诱导凋亡，导致细胞周期在S期停滞，并显示出对癌细胞的明显毒性，其对MCF-7细胞的IC50值为3.16 μM。
T63917	Anticancer agent 67	Others	Others
	Anticancer agent 67 是环丙沙星类似物，是一种抗癌剂，在 MCF-7 细胞中能够诱导细胞凋亡 (apoptosis) 并增加亚 G1 细胞群。
T63521	Bcl-2-IN-7	Others	Others
	Bcl-2-IN-7 是 Bcl-2(b 细胞淋巴瘤 -2) 的有效抑制剂，能够下调 Bcl-2 的表达，提高 p53、Bax、caspase-7 mRNA 的表达，能够诱导乳腺癌 MCF-7 细胞周期阻滞和凋亡。Bcl-2-IN-7 对 MCF-7 细胞 (IC50: 20.17 μM)、LoVo 细胞 (IC50: 22.64 μM)、HepG2 细胞 (IC50:45.57 μM) 和 A549 细胞 (IC50: 51.50 μM)均表现出良好的抗肿瘤活性。
T72479	Anticancer agent 66	Others	Others
	Anticancer agent 66 是一种抗癌剂。Anticancer agent 66 在 MCF-7 细胞中诱导细胞凋亡 (apoptosis) 并增加亚 G1 细胞群。Anticancer agent 66 是一种环丙沙星类似物。
T84968	Indium (III) thiosemicarbazone 5b	Others	Others
	Indium (III) thiosemicarbazone 5b is an anticancer compound demonstrating cytotoxicity against various cancer cell lines including A549, MCF-7 breast, cisplatin-resistant MCF-7/DDP breast, and Hl 7702 liver cancer cells, with IC50 values of 2.41, 1.97, 2.11, and 8.95 µM, respectively. It effectively lowers PI3K, Akt, mTOR, P-gp, and GSH levels in MCF-7/DDP cells. In vivo studies show that at a dosage of 2.5 µmol/kg, indium (III) thiosemicarbazone 5b significantly reduces tumor weight and volume ...
T61823	Anticancer agent 63	Others	Others
	Anticancer agent 63 (compound 3h) exhibits significant cytotoxic activity against multiple cancer cell lines, including SW480, HeLa, A549, and MCF-7, with IC 50 values of 4.9, 11.5, 9.4, and 3.4 μM, respectively, after 24 hours of treatment. In particular, Anticancer agent 63 induces apoptosis in MCF-7 cells by down-regulating Bcl-2 expression and up-regulating IL-2 and Caspase-3 expression. Additionally, Anticancer agent 63 demonstrates antioxidative properties [1].
T63205	HSP90-IN-13	Others	Others
	HSP90-IN-13（compound 5k）是一种有效的HSP90抑制剂，具有25.07 nM的IC50值，并对EGFR、VEGFR-2以及Topoisomerase-2展现出多靶点作用。此外，HSP90-IN-13能够在G2/M期阻滞MCF-7细胞周期，并通过线粒体途径诱导细胞凋亡(apoptosis)。
T82715	Cisplatin-resistant cells-IN-1	Others	Others
	Cisplatin-resistant cells-IN-1（化合物8）对顽固的铂类药物抗性细胞具有较高的细胞毒性。在低纳摩尔浓度范围内（IC50：0.14–1.79 μM in A549/A549-R, K562/K562-R, and MCF-7/MCF-7TamR cells），该化合物能有效降低代谢活性。
T36744	CDK9 Antagonist-1 CDK9 Antagonist-1	Others	Others
	CDK9 Antagonist-1 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form PROTAC[1]. CDK9\|17 μM (IC50, MCF-7 cells) [1]. Bian J , et al. Discovery of Wogonin-based PROTACs against CDK9 and capable of achieving antitumor activity. Bioorg Chem. 2018 Dec;81:373-381.
T78051	Necrocide 1	Others	Others
	Necrocide 1（化合物(S)-38）是一款有效的抗癌药物，具备显著的抗增殖效果，针对MCF-7和PC3细胞株的IC50值分别为0.48 nM及2 nM。
T83018	Antiproliferative agent-39	Others	Others
	Antiproliferative agent-39 (Compound 12)于 A549、SNU-638、Col2、HT1080、MCF-7 细胞系展现抑制增殖作用，其 IC50 值分别为 11、25、14、11, 6.3 μM。
T79727	EGFR/CDK2-IN-2	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR/CDK2-IN-2（compound 6a）是一种针对EGFR和CDK-2的双重抑制剂，具有19.6 nM和87.9 nM的IC50s。该化合物能在MCF-7细胞内诱导凋亡，并在S期引发细胞周期停滞。此外，EGFR/CDK2-IN-2展现出IC50为0.39 μM的显著抗癌活性，对MCF-7细胞具有强效的细胞毒性。
T79400	VEGFR-2-IN-35	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	VEGFR-2-IN-35（compound 7）作为 VEGFR-2 抑制剂，展示出37 nM 的IC50值；同时，该化合物对MCF-7 和 HCT 116 癌细胞的抑制效果显著，IC50值分别为10.56 μM 和7.07 μM。
T74340	DNA crosslinker 4 dihydrochloride	Others	Others
	DNA crosslinker 4 (dihydrochloride) 作为高效的DNA小沟结合剂，对NCI-H460、A2780和MCF-7癌细胞表现出显著抑制活性，适用于抗癌研究。
T79729	EGFR/CDK2-IN-4	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR/CDK2-IN-4（化合物4c）是一种EGFR与CDK-2的双重抑制剂，其IC50值分别为89.6 nM和165.4 nM。该化合物在MCF-7细胞中能诱导(apoptosis)凋亡，并导致细胞周期在S期停滞。EGFR/CDK2-IN-4显示出显著的抗癌细胞毒性，对MCF-7细胞的IC50为2.74 μM。
T79651	EGFR-IN-83	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-83（化合物9）为EGFR抑制剂，IC50为2.53 nM。该化合物对MCF-7及MDA-MB-231细胞显示出抗增殖作用，其IC50值分别为2.50 μM及1.96 μM。此外，EGFR-IN-83能够诱导细胞凋亡。
T64026	ERα antagonist 1	Others	Others
	ERα antagonist 1 是选择性的、有效的、共价雌激素受体 α (ERα)拮抗剂。ERα antagonist 1 能够将 MCF-7 细胞的细胞周期阻滞在 G0/G1 期，并诱导其凋亡 (apoptosis)。
T79383	ER degrader 7	Others	Others
	ER degrader 7 (Compound 35t) 是一种既能降解ERα又能降解ERβ的化合物。该化合物具有抑制微管蛋白聚合的功能，并能有效降低多种细胞系（包括MCF-7、T47D、MCF-10A、LCC2、T47D D538G与T47D Y537S）的细胞活性，相应IC50s值分别为0.06、2.56、15.84、1.59、1.67、1.37 μM。此外，ER degrader 7 对乳腺癌肿瘤生长同样有抑制作用。
T63455	PI3K/Akt/mTOR-IN-3	Others	Others
	PI3K/Akt/mTOR-IN-3 是 PI3K/Akt/mTOR 的有效抑制剂。PI3K/Akt/mTOR-IN-3 能够抑制 MCF-7 细胞 (IC50: 0.77 μM)、HeLa 细胞 (IC50: 1.23 μM) 和 HepG2 细胞(IC50: 4.57 μM)。PI3K/Akt/mTOR-IN-3 在 4 μM 浓度下可抑制 MCF-7 和 HeLa 细胞的迁移。PI3K/Akt/mTOR-IN-3 能够将细胞周期阻滞在 S 期，并诱导细胞凋亡 (apoptosis)。
T69888	SB02024	Others	Others
	SB02024 is a VPS34 inhibitor. SB02024 activates cGAS-STING signaling and sensitizes tumors to STING agonist. SB02024 blocked autophagy in vitro and reduced xenograft growth of two breast cancer cell lines, MDA-MB-231 and MCF-7, in vivo. Vps34 inhibitor significantly potentiated cytotoxicity of Sunitinib and Erlotinib in MCF-7 and MDA-MB-231 in vitro in monolayer cultures and when grown as multicellular spheroids. Our data suggests that inhibition of autophagy significantly improves sensitivity...
T13685	ERD-308	Others; PROTACs	Others; PROTAC
	ERD-308 induces >95% of ER degradation at concentrations as low as 5 nM in both cell lines (DC50 (concentration causing 50% of protein degradation) of 0.17 nM and 0.43 nM in MCF-7 and T47D ER+ cells, respectively).ERD-308 is a highly potent PROTAC degrade
T83078	Anticancer agent 33	Others	Others
	Anticanceragent 33 (compound 3) 为Squamocin与Bullatacin衍生物，展现出有效的抗癌特性。本化合物对4T1乳腺癌细胞系（包括A549、HeLa、HepG2和MCF-7细胞）的生长抑制作用显著，其IC50范围为1.9-5.4 µM。
T37027	MHAPC-Chol	Others	Others
	MHAPC-Chol is a cationic cholesterol. MHAPC-Chol, as part of a lipoplex with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells in a luciferase assay without affecting cell viability. It has also been used to deliver siRNA into mice via intravenous injection, resulting in MHAPC-chol accumulation in the liver.
T61032	Carbonic anhydrase inhibitor 10	Others	Others
	Carbonic anhydrase inhibitor 10 可用于研究癌症，它对 MCF-7 癌细胞表现出抗增殖活性， IC50值为 11.9 μM。Carbonic anhydrase inhibitor 10 是 hCA IX 的有效抑制剂，Ki 值为 6.2 nM。
T17728	PROTAC CDK9 degrader-2	Others	Others
	PROTAC CDK9 degrader-2 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form PROTAC[1].
T61717	Topoisomerase I inhibitor 4	Others	Others
	Topoisomerase I inhibitor 4 (compound 7a) is a potent inhibitor of topoisomerase I activity. It effectively inhibits the proliferation of various cancer cell lines including HepG2, A549, MCF-7, and HeLa, with IC50 values of 1.20 μM, 2.09 μM, 1.56 μM, and 1.92 μM, respectively. Thus, Topoisomerase I inhibitor 4 holds promise for cancer research applications [1].
T81249	Ru3	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Ru3是一种poly(ADP-ribose)polymerase 1抑制剂，能够通过诱导DNA损伤、抑制DNA修复机制、扰乱细胞周期、降低线粒体膜电位及增加reactive oxygen species水平来诱导MCF-7细胞的apoptosis。
T82931	Aurora A inhibitor 3	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Aurora A inhibitor3 (Compound 5h) 是一种抑制Aurora-A激酶活性的化合物，IC50为0.78 μM。该化合物同时对MCF-7和MDA-MB-231细胞线表现出细胞毒性，其GI50值分别为0.12 μM和0.63 μM。
T36458	CAY10701 CAY10701	Others	Others
	CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively). It also inhibits the growth of several different colorectal cancer cell lines (GI50 values range from 9 to 17 nM), while being at least 1,500-fold less effective against normal human fibroblast WI38 cells. CAY10701 is effective in vivo, reducing tumor volume in colorectal cell xenografts in mice without significantly altering body ...
T74338	DNA crosslinker 2 dihydrochloride	Others	Others
	DNA crosslinker 2 (dihydrochloride)为一种高效DNA小沟结合剂，其结合亲和力(ΔTm)达1.2°C。该化合物对NCI-H460、A2780及MCF-7癌细胞展示出抑制活性，适用于抗癌研究。
T72200	Antiproliferative agent-11	Others	Others
	Antiproliferative agent-11 是一种具有抗增殖活性和选择性的 Ruthenium(II)-Tris-pyrazolylmethane 复合物。Antiproliferative agent-11 对 MCF-7，HeLa，518A2，HCT116 和 RD 细胞具有抗增殖活性，其 IC50值分别为 6，10，6.8，6.7 和 6 μM。Antiproliferative agent-11 可用于癌症的研究。
T36868	4-oxo Docosahexaenoic Acid	Others	Others
	4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 μM.
T37035	HAPC-Chol	Others	Others
	HAPC-Chol is a cationic cholesterol. HAPC-Chol, as part of a lipoplex with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells in a luciferase assay without affecting cell viability. It has also been used to deliver siRNA into mice via intravenous injection, resulting in HAPC-chol accumulation in the lungs.
T36449	(S)-α-Methylbenzyl Ricinoleamide	Others	Others
	(S)-α-Methylbenzyl ricinoleamide is a fatty acid amide derived from ricinoleic acid and methyl benzylamine. It demonstrates potent growth inhibition of glioma (U251), breast (MCF-7), ovarian (NCI-ADR/RES and OVCAR-3), kidney (786-0), non-small cell lung (NCI-H460), and prostate (PC-3) cancer cells with a mean GI50 value of 6.9 μM.
T78980	Pim-1 kinase inhibitor 5	Pim	Chromatin/Epigenetic; JAK/STAT signaling
	Pim-1 kinase inhibitor 5 (Compound 4c)是一种选择性Pim-1激酶抑制剂，具有0.61 μM的半抑制浓度(IC50)。该化合物对HepG2、MCF-7、PC3和HCT-116癌细胞系表现出细胞毒性，其IC50s值介于6.95至20.19 μM之间。
T79367	CDK9-IN-27	CDK	Cell Cycle/Checkpoint
	CDK9-IN-27（Compound 6a）是一款针对CDK9的抑制剂，其IC50s为0.424 μM。该化合物可诱导细胞凋亡（apoptosis）及S期细胞周期停滞，并对HepG2、HCT-116及MCF-7细胞系展现出细胞毒性，其IC50s介于10.31至40.34 μM之间。CDK9-IN-27主要应用于癌症相关研究领域。
T82759	CDK2-IN-20	CDK	Cell Cycle/Checkpoint
	CDK2-IN-20 是一种对CDK2具有抑制作用的化合物。该化合物对肿瘤细胞表现出细胞毒性，其半抑制浓度(IC50)介于5.52至17.09 µM之间。CDK2-IN-20 作用于MCF-7细胞，能够引起细胞周期在S期的阻滞，并诱导细胞发生凋亡。

化合物

Cat.No: T9541

Synonym: Cholera Toxin B subunit

Target: Epigenetic Reader Domain

Cat.No: T15578

Synonym: NSC-724998,LMP-400

Target: Topoisomerase

Cat.No: T77718

Target: FAK

Cat.No: T36970

Target: DUB

Cat.No: T21804

Target: Others

Pim-1 kinase inhibitor 8

Cat.No: T83627

Target: Pim, PKC

Cat.No: T5350

Synonym: JG98,JG 98

Target: Apoptosis, HSP

Cat.No: T7057

Target: Histone Demethylase, Others

Cat.No: T31988

Target: Others

Cat.No: T10695

Target: Others

Estrogen receptor modulator 8

Cat.No: T79109

Target: Estrogen Receptor/ERR

Cat.No: T63676

Target: Others

Cat.No: T83874

Target: Others

Cat.No: T79728

Target: EGFR

Anticancer agent 67

Cat.No: T63917

Target: Others

Cat.No: T63521

Target: Others

Anticancer agent 66

Cat.No: T72479

Target: Others

Indium (III) thiosemicarbazone 5b

Cat.No: T84968

Target: Others

Anticancer agent 63

Cat.No: T61823

Target: Others

Cat.No: T63205

Target: Others

Cisplatin-resistant cells-IN-1

Cat.No: T82715

Target: Others

CDK9 Antagonist-1

Cat.No: T36744

Synonym: CDK9 Antagonist-1

Target: Others

Cat.No: T78051

Target: Others

Antiproliferative agent-39

Cat.No: T83018

Target: Others

Cat.No: T79727

Target: EGFR

Cat.No: T79400

Target: VEGFR

DNA crosslinker 4 dihydrochloride

Cat.No: T74340

Target: Others

Cat.No: T79729

Target: EGFR

Cat.No: T79651

Target: EGFR

ERα antagonist 1

Cat.No: T64026

Target: Others

Cat.No: T79383

Target: Others

PI3K/Akt/mTOR-IN-3

Cat.No: T63455

Target: Others

Cat.No: T69888

Target: Others

Cat.No: T13685

Target: Others, PROTACs

Anticancer agent 33

Cat.No: T83078

Target: Others

Cat.No: T37027

Target: Others

Carbonic anhydrase inhibitor 10

Cat.No: T61032

Target: Others

PROTAC CDK9 degrader-2

Cat.No: T17728

Target: Others

Topoisomerase I inhibitor 4

Cat.No: T61717

Target: Others

Cat.No: T81249

Target: PARP

Aurora A inhibitor 3

Cat.No: T82931

Target: Aurora Kinase

Cat.No: T36458

Synonym: CAY10701

Target: Others

DNA crosslinker 2 dihydrochloride

Cat.No: T74338

Target: Others

Antiproliferative agent-11

Cat.No: T72200

Target: Others

4-oxo Docosahexaenoic Acid

Cat.No: T36868

Target: Others

Cat.No: T37035

Target: Others

(S)-α-Methylbenzyl Ricinoleamide

Cat.No: T36449

Target: Others

Pim-1 kinase inhibitor 5

Cat.No: T78980

Target: Pim

Cat.No: T79367

Target: CDK

Cat.No: T82759

Target: CDK

Cat. No.	Product Name	Target	Signaling Pathways
TN2105	Proscillaridin A	Topoisomerase	DNA Damage/DNA Repair
	Proscillaridin A 是从Drimia robusta 中提取的一种天然产物。是强力的拓扑异构酶 I 和 II 的抑制剂，IC50值分别为 30 nM 和 100 nM。
TN3049	4-Methoxycinnamyl alcohol	Others	Others
	4-Methoxycinnamyl alcohol 对MCF-7、HeLa 和DU145癌症细胞系显示出毒性，IC50值分别为14.24、7.82和22.10μg/mL。4-methoxycinnamyl alcohol 是从Foeniculum vulgare 中分离出来的。4-Methoxycinnamyl alcohol 没有显示出凋亡作用，却在10μg/mL DNA 碎片研究显示48小时后发生了坏死。
TMS0879	Asiaticoside B 积雪草苷 B,积雪草苷B	Others	Others
	Asiaticoside B 是一种从类叶升麻中分离得到的三萜糖苷，具有抗肿瘤作用。它对 HepG2 和 MCF-7 癌细胞系具有显著的细胞毒性。
T1166	Ellipticine 玫瑰树碱,NSC 71795,Elliptisine	Topoisomerase	DNA Damage/DNA Repair
	Ellipticine (Elliptisine) 是一种有效的抗肿瘤剂，抑制 DNA 拓扑异构酶 II 活性，对白血病、神经母细胞瘤和胶质母细胞瘤有部分活性。
T8724	6-Methoxydihydrosanguinarine	Others	Others
	6-Methoxydihydrosanguinarine 是一种从M. cordata 果实中分离出的生物碱，它对 MCF-7 细胞系(IC50:0.61 μM)和 SF-268 细胞系(IC50:0.54 μM)具有强的细胞毒性。
T4519	Alisol A Alisol-A,泽泻醇 A	Autophagy	Autophagy
	Alisol A (Alisol-A) 是泽泻中的一种三萜类天然产物，可能是一种自噬诱导剂，具有抗癌活性。
T2S0265	Robinin NSC 9222,刺槐素	TLR	Immunology/Inflammation
	Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LRP was explored by monitoring their uptake of Rhodamine 123, but was shown to have minimal effect. Robinin (NSC-9222) was detected in lysates of the human breast cancer cell line MCF-7 using liquid chromatography-tandem maβ spectrometry.
T5724	Neogambogic acid neo-gambogic acid,新藤黄酸	Apoptosis; Others; Antibacterial	Apoptosis; Microbiology/Virology; Others
	Neogambogic acid 是藤黄的有效成分，可诱导细胞凋亡并具有抗癌作用。它有效抑制耐甲氧西林的金黄色葡萄球菌。
TN1727	Helichrysetin 4,2',4'-三羟基-6'-甲氧基查耳酮,蜡菊亭	Apoptosis; HIV Protease	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Helichrysetin 是从豆蔻果实中分离出的一种天然产物，是一种 DNA 结合抑制剂，可抑制原位导管癌DCIS 的形成。它抑制细胞生长，可诱导 A549 细胞凋亡。
T5S1607	Morusin Mulberrochromene,桑辛素	NF-κB; Antibacterial; STAT	JAK/STAT signaling; Microbiology/Virology; NF-κB; Stem Cells
	Morusin (Mulberrochromene) 是从M. australis 分离的去乙烯基化黄酮，可抑制NF-κB 和STAT3的活性，具有抗菌、抗肿瘤、抗氧化等各种生物活性。
T5S0506	Rotundic acid Rutundic acid,铁冬青酸	Apoptosis; Others; p38 MAPK; Akt; mTOR	Apoptosis; Cytoskeletal Signaling; MAPK; Others; PI3K/Akt/mTOR signaling
	Rotundic acid (Rutundic acid) 是一种从圆形肠球菌中获得的三萜类天然产物，具有抗炎和保护心脏的能力。它可通过 AKT/mTOR 和 MAPK 途径在肝细胞癌中诱导 DNA 损伤和细胞凋亡。
TN2755	2-Desoxy-4-epi-pulchellin	Anti-infection	Microbiology/Virology
	2-Desoxy-4-epi-pulchellin 是分离自 Polygonum hydropiper 的二氯甲烷可溶部分的一种化合物。
TN3972	Epimedokoreanin B	Apoptosis; Others; Antibacterial	Apoptosis; Microbiology/Virology; Others
	Epimedokoreanin B （EKB）是一种从韩国淫羊藿中分离出的异戊烯化类黄酮，在人非小细胞肺癌（NSCLC）A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性，可有清除 DPPH 自由基的活性，能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -（羧甲基）赖氨酸（CML）和 N (Ï) -（羧甲基）精氨酸（CMA）的形成，可通过抑制高级糖化终产物（AGEs）预防糖尿病的临床并发症。
T5S2358	Dehydrocorydaline Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine	BCL; PARP; p38 MAPK; Caspase; Parasite; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Proteases/Proteasome
	Dehydrocorydaline (13-Methylpalmatine) 是一种生物碱。它调节Bax，Bcl-2蛋白表达，激活caspase-7，caspase-8，并使PARP 失活。它能增强p38 MAPK 活化，具有抗炎、抗癌等功效。它具有强大的抗疟疾作用，并具低细胞毒性。
T6S1315	Oroxylin A 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease; HIF/HIF Prolyl-Hydroxylase; Autophagy	Autophagy; Chromatin/Epigenetic; Metabolism; Microbiology/Virology
	Oroxylin A (Baicalein 6-methyl ether) 是一种有活性的黄酮，具有较强的抗癌作用。
T3729	Ethyl gallate Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯	MMP; NF-κB; Akt; Antibacterial	Cytoskeletal Signaling; Microbiology/Virology; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Ethyl gallate (gallic acid ethyl ester) 是一种非类黄酮酚过氧化氢清除剂。
T17155	Trabectedin Ecteinascidin 743,曲贝替定,ET-743	Apoptosis; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	Trabectedin (Ecteinascidin 743) 是一种四氢异喹啉生物碱，有抗肿瘤的活性，通过与 DNA 的小沟结合，阻断应激诱导的蛋白质的转录，诱导 DNA 骨架裂解和癌细胞凋亡，并增加 MCF-7 和 MDA-MB-453 细胞中 ROS 的生成。Trabectedin 在软组织肉瘤和卵巢癌中具有的研究价值。
TN4307	Isolimonexic acid	BCL; Caspase; COX; p53	Apoptosis; Immunology/Inflammation; Neuroscience; Proteases/Proteasome
	Isolimonexic acid exhibits cytotoxicity on MCF-7 cell lines, it also inhibits Panc-28 cancer cell growth.
T13551	Araliadiol	Others	Others
	Araliadiol is a polyacetylenic compound isolated from the leaves of Aralia cordata Thunb. Araliadiol inhibits MCF-7 cell growth (IC50: 6.41 µg/mL).
TN5287	3β,5α-Dihydroxyergosta-7,22-dien-6-one
	3β,5α-Dihydroxy-(22E,24R)-ergosta-7,22-dien-6-one exhibits strong or moderate cytotoxic activities against MCF-7, A549, Hela and KB cell lines with IC50 values 4.98 (MCF-7), 1.95 (A549), 0.68(Hela), and 1.50 uM (KB), respectively.
TN5676	Musellarin B
	Musellarin B is cytotoxic toward several of the human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW480).
T40940	7,3′,5′-Trihydroxyflavanone	Others	Others
	7,3′,5′-Trihydroxyflavanone, a flavanoid derivative, promotes apoptotic cell death in MCF-7 cells by augmenting Bax expression. Additionally, this compound demonstrates antioxidant properties.
TN3250	7-Prenyljacareubin	Others	Others
	7-Prenyljacareubin shows moderate cytotoxic activity against HL-60, SMMC-7721, A549, MCF-7, and SW480 cell lines.
T83301	5,7-Dimethoxy-2,3-phenanthrenediol
	5,7-Dimethoxy-2,3-phenanthrenediol 表现出雌激素活性，能够促进MCF-7细胞的增殖，并增强ERβ在MCF-7细胞系中的表达。
TN4629	Nemoralisin C	Others	Others
	Nemoralisin C shows antiproliferative activity against HepG2, AGS, MCF-7, and A-549 cancer cell lines.
TN4116	Garjasmin	Others	Others
	Garjasmine exhibits weak cytotoxic activity against KB and MCF-7 cell lines.
TN4630	Nemoralisin	Others	Others
	Nemoralisin exhibits weak cytotoxicities (IC50>10 uM) against HepG2, AGS, MCF-7, and A-549 cancer cell lines.
TN1942	Momordicoside F1 苦瓜皂苷 F1	Others	Others
	Momordicoside F1 may have antiproliferative activities against MCF-7, WiDr, HEp-2, and Doay human tumor cell lines.
TN1523	Conicasterol	Others	Others
	Conicasterol displays marked cytotoxic activity against human breast adenocarcinoma cell line (MCF-7) with the IC50 value of 6.23 ug/mL.
TN2825	25-Anhydrocimigenol 3-O-beta-D-xyloside	Others	Others
	25-Anhydrocimigenol 3-O-beta-D-xyloside has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.
TN2828	25-O-ethylcimigenol-3-O-beta-D-xylopyranoside	Others	Others
	25-O-ethylcimigenol-3-O-beta-D-xylopyranoside has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.
TN4355	Jolkinol A	Others	Others
	Jolkinol A can inhibit both MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) cell lines, with GI50 values ranging between 40.9 microM and 95.3 microM.
TN1679	Genistein 7,4'-di-O-β-D-glucoside 染料木素-7,4'-二-O-Β-D-葡萄糖苷,Genistein 7,4'-di-O-beta-D-glucopyranoside,鲁冰花	Others; Estrogen/progestogen Receptor	Endocrinology/Hormones; Others
	Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range.
TN4299	Isoiridogermanal	Others	Others
	Isoiridogermanal shows similar cytotoxicity with IG(50) around 11 microM and 23 microM against MCF-7 and C32 cell lines, respectively.
TN3371	Albatrelin G	Others	Others
	Albatrelin G shows weak cytotoxic activity to cell lines HL-60, SMMC-7721, A-549, and MCF-7, in vitro.
TN2184	Schisanlactone E 五内脂	Others	Others
	Schisanlactone E may show moderate cytotoxic activity against the human tumor cell lines Bel-7402, BGC-823, MCF-7 and HL-60.
TN1392	Anhydrosecoisolariciresinol	Others	Others
	Anhydrosecoisolariciresinol can significantly decrease the growth of human breast cancer MCF-7 and MDA-MB-231 cell lines at 50 and 100 microM.
TN7378	Alopecurone A	Others	Others
	Alopecurone A demonstrates potent inhibitory effects on MRP1, exhibits cytotoxic activity against DU145 (prostate cancer cell line) and MCF-7 (breast cancer cell line) with IC50 values of 2.44 and 5.44 μg/mL, respectively, and possesses antibacterial activity against methicillin-resistant Staphylococcus aureus.
T81686	Neotriptonoterpene
	Neotriptonoterpene 是一种从 T. regelii 分离得到的化合物，在 A2780、HepG2 和 MCF-7 细胞上具有较弱的细胞毒活性，其 IC50 值分别为 65.80 µM、35.45 µM 和 64.80 µM。
TN4963	Scillascillin	Others	Others
	Scillascillin has anticancer activity, it is significantly active against human cancer cell lines MCF-7 (breast cancer) and DU-145 (prostate cancer) with inhibitory concentration (IC)50 values 9.59 and 11.32 ug/ml respectively.
TN1139	Dehydrocavidine Dehydrocorydaline,岩黄连碱	BCL; PARP	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Dehydrocavidine (Dehydrocorydaline) 具有抗肿瘤活性，它通过诱导调节 Bax/Bcl-2 介导的细胞凋亡、激活半胱天冬酶以及切割 PARP 来抑制 MCF-7 细胞增殖。
TN2752	2-Deacetoxytaxinine J	Others	Others
	2-Deacetoxytaxinine J shows significant in vitro activity against breast cancer cell line at a concentration of 20 microM and 10 microM in MCF-7 and MDA-MB-231 respectively.
TN3237	7-Isopentenyloxy-gamma-fagarine	Others	Others
	7-Isopentenyloxy-gamma-fagarine has highly cytotoxicity against the MCF-7and Jurkat cell line. It has been used as a precursor for the chemical asymmetric synthesis of the enantiopure alkaloids: evoxine, anhydroevoxine and evodine.
TN2052	Periplocoside M	Others	Others
	Periplocoside M possesses observably antitumor activity against SMMC-7721( IC 50=12.9 ng/L),Hela( IC 50=8.63 ng/L) and MCF-7( IC 50=18.5 ng/L) cancer cell lines.
T83578	(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol
	(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol 是一种葫芦烷型三萜。该化合物在 MTT 法检测中对癌细胞系 MCF-7、HepG2、Du145、Colon205 以及 HL-60 均未表现出抑制效果。
T75490	27-O-(tert-Butyldimethylsilyl)withaferin A	Others	Others
	27-O-(tert-Butyldimethylsilyl)withaferin A (compound 9a) 为一种天然茄内酯类化合物，具备诱导细胞凋亡 (apoptosis) 的能力。该化合物对人类癌细胞系HeLa、A-549、MCF-7以及正常Vero细胞展现出抗增殖活性。
TN6062	1,3,9-Trimethyluric acid
	1,3,9-Trimethyluric acid exhibits in vitro cytotoxic activity against breast cancer (MCF-7), human neuroblastoma (SHSY5Y), human non-small cell lung cancer (A549) and human liver cancer (HEPG2) with IC50 value in the range of 1-3 uM. 1,3,9-Trimethyluric a
TN2979	3-Oxotirucalla-7,24-dien-21-oic acid	Others	Others
	3-Oxotirucalla-7,24-dien-21-oic acid 是首次从蓼属植物中分离得到的已知化合物，可从黑参根中分离得到。3-Oxotirucalla-7,24-dien-21-oic acid 对 MCF-7细胞系显示出强大的细胞毒性。
T81540	Parthenosin Quercetin 3-O-β-D-glucuronide butyl ester
	Parthenosin (Quercetin 3-O-β-D-glucuronide butester) 是从Calligoum foamoides地上部分分离得到的黄酮类化合物，对HepG2和MCF-7细胞系表现出明显的细胞毒性，其IC50值分别为60.46μg/mL和61.4μg/mL。
TN4264	Isoapetalic acid 胡桐，海棠木	HIV Protease; Antifection	Microbiology/Virology; Proteases/Proteasome
	Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell lines) and both Gram-positive bacteria(two Gram-positive bacteria, S. aureus and B. subtilis a
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天然产物

Proscillaridin A

Cat.No: TN2105

Target: Topoisomerase

4-Methoxycinnamyl alcohol

Cat.No: TN3049

Target: Others

Cat.No: TMS0879

Synonym: 积雪草苷 B,积雪草苷B

Target: Others

Cat.No: T1166

Synonym: 玫瑰树碱,NSC 71795,Elliptisine

Target: Topoisomerase

6-Methoxydihydrosanguinarine

Cat.No: T8724

Target: Others

Cat.No: T4519

Synonym: Alisol-A,泽泻醇 A

Target: Autophagy

Cat.No: T2S0265

Synonym: NSC 9222,刺槐素

Target: TLR

Neogambogic acid

Cat.No: T5724

Synonym: neo-gambogic acid,新藤黄酸

Target: Apoptosis, Others, Antibacterial

Cat.No: TN1727

Synonym: 4,2',4'-三羟基-6'-甲氧基查耳酮,蜡菊亭

Target: Apoptosis, HIV Protease

Cat.No: T5S1607

Synonym: Mulberrochromene,桑辛素

Target: NF-κB, Antibacterial, STAT

Cat.No: T5S0506

Synonym: Rutundic acid,铁冬青酸

Target: Apoptosis, Others, p38 MAPK, Akt, mTOR

2-Desoxy-4-epi-pulchellin

Cat.No: TN2755

Target: Anti-infection

Epimedokoreanin B

Cat.No: TN3972

Target: Apoptosis, Others, Antibacterial

Dehydrocorydaline

Cat.No: T5S2358

Synonym: Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Cat.No: T6S1315

Synonym: 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Cat.No: T3729

Synonym: Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯

Target: MMP, NF-κB, Akt, Antibacterial

Cat.No: T17155

Synonym: Ecteinascidin 743,曲贝替定,ET-743

Target: Apoptosis, Reactive Oxygen Species

Isolimonexic acid

Cat.No: TN4307

Target: BCL, Caspase, COX, p53

Cat.No: T13551

Target: Others

3β,5α-Dihydroxyergosta-7,22-dien-6-one

Cat.No: TN5287

Cat.No: TN5676

7,3′,5′-Trihydroxyflavanone

Cat.No: T40940

Target: Others

7-Prenyljacareubin

Cat.No: TN3250

Target: Others

5,7-Dimethoxy-2,3-phenanthrenediol

Cat.No: T83301

Cat.No: TN4629

Target: Others

Cat.No: TN4116

Target: Others

Cat.No: TN4630

Target: Others

Momordicoside F1

Cat.No: TN1942

Synonym: 苦瓜皂苷 F1

Target: Others

Cat.No: TN1523

Target: Others

25-Anhydrocimigenol 3-O-beta-D-xyloside

Cat.No: TN2825

Target: Others

25-O-ethylcimigenol-3-O-beta-D-xylopyranoside

Cat.No: TN2828

Target: Others

Cat.No: TN4355

Target: Others

Genistein 7,4'-di-O-β-D-glucoside

Cat.No: TN1679

Synonym: 染料木素-7,4'-二-O-Β-D-葡萄糖苷,Genistein 7,4'-di-O-beta-D-glucopyranoside,鲁冰花

Target: Others, Estrogen/progestogen Receptor

Isoiridogermanal

Cat.No: TN4299

Target: Others

Cat.No: TN3371

Target: Others

Schisanlactone E

Cat.No: TN2184

Synonym: 五内脂

Target: Others

Anhydrosecoisolariciresinol

Cat.No: TN1392

Target: Others

Cat.No: TN7378

Target: Others

Neotriptonoterpene

Cat.No: T81686

Cat.No: TN4963

Target: Others

Dehydrocavidine

Cat.No: TN1139

Synonym: Dehydrocorydaline,岩黄连碱

Target: BCL, PARP

2-Deacetoxytaxinine J

Cat.No: TN2752

Target: Others

7-Isopentenyloxy-gamma-fagarine

Cat.No: TN3237

Target: Others

Periplocoside M

Cat.No: TN2052

Target: Others

(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol

Cat.No: T83578

27-O-(tert-Butyldimethylsilyl)withaferin A

Cat.No: T75490

Target: Others

1,3,9-Trimethyluric acid

Cat.No: TN6062

3-Oxotirucalla-7,24-dien-21-oic acid

Cat.No: TN2979

Target: Others

Cat.No: T81540

Synonym: Quercetin 3-O-β-D-glucuronide butyl ester

Isoapetalic acid

Cat.No: TN4264

Synonym: 胡桐，海棠木

Target: HIV Protease, Antifection

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00655	TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His） TRAIL-R1,TNFRSF10A,cytotoxic TRAIL receptor,APO2,CD261 antig...	Human	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TNFRSF10A / DR4 is widely expressed and high levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells. APO2 / TNFRSF10A is receptor for the cytotoxic ligand TNFSF...
TMPY-02763	DEP-1 Protein, Human, Recombinant (aa 997-1337, His) HPTPeta,SCC1,protein tyrosine phosphatase, receptor type, J,...	Human	E. coli
	DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. DEP1 / PTPRJ possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-...
TMPY-06036	FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) FGFR-1,FLG,CD331,HH2,FLT2,KAL2,FGFBR,HBGFR,CEK,HRTFDS,fibrob...	Human	HEK293 Cells
	FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7.
TMPK-00828	Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc) PEMT,Episialin,Mucin1,PUM,KL-6,MUC-1,Mucin-1,H23AG,PEM,CA 15...	Human	HEK293 Cells
	MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers.
TMPK-00392	FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) CD331,FGFR-1,FLT-2,BFGFR,N-sam,FGFR1 β (IIIc),bFGF-R-1	Human	HEK293 Cells
	Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession numb...
TMPK-01371	IGFBP-7 Protein, Human, Recombinant (hFc) RAMSVPS,TAF,IGFBPRP1,AGM,IBP7,MAC25,IGFBP-7	Human	HEK293 Cells
	IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Human, Recombinant (hFc) is expres...
TMPK-00394	FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,bFGF-R-1,CD331,FGFR-1	Human	HEK293 Cells
	Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the ...
TMPY-06035	FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) KAL2,OGD,N-SAM,CEK,FLT2,HH2,FLG,CD331,BFGFR,HBGFR,FLT-2,FGFB...	Human	HEK293 Cells
	FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is P11362-7.
TMPK-00395	FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated FGF R1a,FGFR1 α,FGFR1 alpha,FGFR1 α (IIIc)	Human	HEK293 Cells
	FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
TMPK-00393	FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) FGFR1 α,FGFR1 alpha,FGF R1a,FGFR1 α (IIIc)	Human	HEK293 Cells
	FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.

重组蛋白

TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His）

Cat.No: TMPJ-00655

Species: Human

Expression System: HEK293 Cells

DEP-1 Protein, Human, Recombinant (aa 997-1337, His)

Cat.No: TMPY-02763

Species: Human

Expression System: E. coli

FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)

Cat.No: TMPY-06036

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00828

Species: Human

Expression System: HEK293 Cells

FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00392

Species: Human

Expression System: HEK293 Cells

IGFBP-7 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-01371

Species: Human

Expression System: HEK293 Cells

FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00394

Species: Human

Expression System: HEK293 Cells

FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)

Cat.No: TMPY-06035

Species: Human

Expression System: HEK293 Cells

FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00395

Species: Human

Expression System: HEK293 Cells

FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00393

Species: Human

Expression System: HEK293 Cells

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