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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6967 |
RHPS4
RHPS 4 methosulfate,NSC714187 |
Apoptosis; Telomerase | Apoptosis; DNA Damage/DNA Repair |
RHPS4 (RHPS 4 methosulfate) 是 DNA 损伤诱导剂,是一种有效的亚微摩尔端粒酶抑制剂,IC50为0.33 μM。 | |||
T9901A-017 |
AM14
|
Others | Others |
AM14 是一种强效的人源 RSV 抗体,有效地中和来自 A 和 B 亚型的 RSV 的实验室菌株和临床分离株。 | |||
T9598 |
NCATS-SM1441
|
||
NCATS-SM1441 在生命科学相关研究中具有广泛的应用。 | |||
T25141 |
BDM14471
BDM-14471,BDM 14471 |
Others | Others |
BDM14471 is a selective inhibitor of hydroxamate PfAM1. | |||
T62916 |
GEM144
|
Others | Others |
GEM144 是一种有效的、口服具有活力的 DNA polymerase α(POLA1) 和HDAC 11 双重抑制剂。GEM144 能够诱导 p53 乙酰化、激活 p21,将细胞周期阻滞在 G1/S 期,并诱导细胞凋亡。 | |||
T70033 |
NCATS-SM1440
|
Others | Others |
NCATS-SM1440 is a Lactate Dehydrogenase Inhibitor with Optimized Cell Activity and Pharmacokinetic Properties. | |||
T8791 |
HlyU inhibitor CM14 (1025E12)
|
Others | Others |
HlyU inhibitor CM14 (1025E12) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T8791,CAS号为 588678-13-1。 | |||
T36468 |
ARN14988
|
Others | Others |
ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme). It inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361 melanoma cells (EC50s = 41.8 and 67.7 μM, respectively). |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02053 |
RBM14 Protein, Human, Recombinant (His & SUMO)
RNA-binding protein 14,RRM-containing coactivator activator/... |
Human | E. coli |
RBM14 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPJ-01087 |
TIM14 Protein, S. cerevisiae, Recombinant
Mitochondrial import inner membrane translocase subunit TI |
S. cerevisiae | E. coli |
Mitochondrial import inner membrane translocase subunit TIM14 (TIM14) is an essential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM14 is required to stimulate activity of mtHSP70 (SSC1). TIM14 belongs to the DnaJ family, which has been involved in Hsp40/Hsp70 chaperone systems. As a mitochondrial chaperone, TIM14 functions as p... | |||
TMPH-01690 |
TIM14 Protein, Human, Recombinant (GST)
Mitochondrial import inner membrane translocase subunit TI |
Human | E. coli |
Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling. May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity. | |||
TMPJ-01184 |
CPA4 Protein, Mouse, Recombinant (His)
CPA4,Carboxypeptidase A4 |
Mouse | HEK293 Cells |
Carboxypeptidase A4 (CPA4) is a member of the peptidase M14 family. CPA4 is metalloprotease that could be involved in the histone hyperacetylation pathway. CPA4 binds one zinc ion per subunit and could catalyze to release of a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val.They have distinct expression patterns and different specificities for example, preferentially cleaving aromatic (carboxypeptidase As) or basic (carboxypeptidase Bs) residues. Several, such as... | |||
TMPJ-00649 |
CPB2 Protein, Human, Recombinant (His)
CPB2,CPU,TAFI,pCPB,Carboxypeptidase B2,Plasma Carboxypeptida... |
Human | HEK293 Cells |
Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen by the liver and circulates in the plasma as a plasminogen-bound zymogen. CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides, such as kinins or anaphylatoxins, in the circulation regulating their activities. CPB2 also down-regulates fibrinolysis by removing C-terminal lysine residu... |