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Search Results for " linezolid "

Targets Recommended: MAO Antibacterial Antibiotic

13

抑制剂 & 化合物

1

天然产物

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T0391	Linezolid PNU-100766,雷奈佐利	MAO; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology; Neuroscience
	Linezolid (PNU-100766) 是恶唑烷酮类合成抗生素，抑制细菌蛋白质合成的起始阶段，具有抗感染作用。
T39154	Demethyl linezolid	Others	Others
	Demethyl linezolid is an impurity observed in linezolid, an antimicrobial compound. It exhibits effective antimicrobial properties against various human and veterinary pathogens.
T12627	(R)-Linezolid (R)-PNU-100766	Others	Others
	(R)-Linezolid is an impurity of Linezolid . Linezolid acts by inhibiting the initiation of bacterial protein synthesis.
T19645	PNU-100440 (5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮	Others	Others
	PNU-100440 是一种生物活性化合物。它是合成利奈唑胺二聚物的中间体，利奈唑胺二聚物是抗菌剂利奈唑胺的杂质。
T4165	Delpazolid LCB01-0371	Antibacterial; Antibiotic	Microbiology/Virology
	Delpazolid (LCB01-0371) 是一种恶唑烷酮类新型抗生素，能抑制MSSA 和MRSA 的生长，对它们的MIC90值都为 2 μg/mL。
T16718	Radezolid RX-1741,雷得唑来	Antibacterial; Antibiotic	Microbiology/Virology
	Radezolid (RX-1741) 是一种噁唑烷酮类抗生素。它对衣原体，军团菌葡萄球菌，和Linezolid 耐药菌株有活性。
T37841	PNU 142300	Others	Others
	PNU 142300 is an inactive metabolite of the oxazolidinone antibiotic linezolid .
T37465	CAY10742	Others	Others
	CAY10742 is an orally bioavailable oxadiazole antibiotic.1It is active against the Gram-positive bacteriaS. aureus,S. epidermidis,S. haemolyticus,B. cereus,B. licheniformis,E. faecalis, andE. faecium(MICs = 1-4 μg/ml), including laboratory strains and clinical isolates with varying degrees of resistance to methicillin, vancomycin, linezolid, and other antibiotics. CAY10742 (40 mg/kg) reduces the number of bacteria in mouse neutropenic thigh models of linezolid-sensitive or -resistant methicillin...
T69176	YycG inhibitor 16	Others	Others
	YycG inhibitor 16 is a novel YycG inhibitor, inhibiting planktonic cells of E. faecalis, including the vancomycin- or linezolid-resistant strains.
T23947	DA-7867 UNII-491MT9GU8K,DA 7867,DA7867	Others	Others
	DA-7867 is a novel oxazolidinone. DA-7867 had the lowest MIC for 90% of the aerobic gram-positive bacterial strains tested (≤0.25 μg/ml) and it was more potent than linezolid. DA-7867 was the most active drug with a MIC(90) of 0.125 μg/ml.
T27964	Voxvoganan LTX109,Lytixar,LTX-109,LTX 109	Others	Others
	Lytixar is a Synthetic Antimicrobial Peptide, it shows activity against Daptomycin-Nonsusceptible, Methicillin-Resistant, Vancomycin-Intermediate, Vancomycin-Resistant, and Linezolid-Nonsusceptible Staphylococcus aureus. LTX-109 demonstrated a MIC range o
T76990	Suvratoxumab
	Suvratoxumab (MEDI4893) 是一种长效且具有亲和力高的人源化抗 α-毒素单克隆抗体(IgG1κ 型)。Suvratoxumab 能有效中和 α-毒素 (一种关键的金黄色葡萄球菌毒力因子)。Suvratoxumab 可提高免疫功能低下的小鼠肺炎模型的存活率并减少肺损伤。Suvratoxumab 还可增强Vancomycin 或Linezolid 的抗菌活性。
T23451	Tedizolid HCl (856866-72-3 free base) Tedizolid HCl	Others	Others
	Tedizolid HCl is a reversible, novel oxazolidinone antibiotic (IC50: for MAO-A (monoamine oxidase-A), 8.7 uM; for MAO-B, 5.7 uM). It is the first oxazolidinone to be approved since linezolid in 2000. Tedizolid phosphate is the second commercially availabl

化合物

Cat.No: T0391

Synonym: PNU-100766,雷奈佐利

Target: MAO, Antibacterial, Antibiotic

Demethyl linezolid

Cat.No: T39154

Target: Others

(R)-Linezolid

Cat.No: T12627

Synonym: (R)-PNU-100766

Target: Others

Cat.No: T19645

Synonym: (5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮

Target: Others

Cat.No: T4165

Synonym: LCB01-0371

Target: Antibacterial, Antibiotic

Cat.No: T16718

Synonym: RX-1741,雷得唑来

Target: Antibacterial, Antibiotic

Cat.No: T37841

Target: Others

Cat.No: T37465

Target: Others

YycG inhibitor 16

Cat.No: T69176

Target: Others

Cat.No: T23947

Synonym: UNII-491MT9GU8K,DA 7867,DA7867

Target: Others

Cat.No: T27964

Synonym: LTX109,Lytixar,LTX-109,LTX 109

Target: Others

Cat.No: T76990

Tedizolid HCl (856866-72-3 free base)

Cat.No: T23451

Synonym: Tedizolid HCl

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN6603	(S)-N-Glycidylphthalimide (S)-N-缩水甘油邻苯二甲酰亚胺,2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione	Others	Others
	(S)-N-Glycidylphthalimide (2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione) 是一种邻苯二甲酰亚胺衍生物，用作制备抗生素利奈唑胺的中间体。

天然产物

(S)-N-Glycidylphthalimide

Cat.No: TN6603

Synonym: (S)-N-缩水甘油邻苯二甲酰亚胺,2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T11853	Linezolid-d3 Linezolid D3,PNU-100766 D3	Others	Others
	Linezolid D3, a deuterium-labeled version of Linezolid, is a synthetic antibiotic designed to halt the initiation of bacterial protein synthesis.

同位素标记化合物

Cat.No: T11853

Synonym: Linezolid D3,PNU-100766 D3

Target: Others

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