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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T84382 LY303511 hydrochloride

Others Others
LY303511, a structural analog of LY294002, selectively inhibits mTOR-dependent phosphorylation of S6K, unlike its counterpart, which acts as a phosphatidylinositol 3-kinase (PI3K) inhibitor. It effectively reduces cell proliferation in human lung epithelial adenocarcinoma cells by hindering G2/M phase progression and suppressing casein kinase 2 activity. Additionally, LY303511 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sensitivity in HeLa cells resistant to TRAIL-in...
T4423 LY 303511 hydrochloride

LY303511 hydrochloride

Potassium Channel; TNF; mTOR Apoptosis; Membrane transporter/Ion channel; PI3K/Akt/mTOR signaling
LY 303511 hydrochlorideLY294002 的一种结构类似物。LY 303511 hydrochloride 可增强 SHEP-1 神经母细胞瘤细胞的TRAIL 敏感性,还可逆地阻断 MIN6 胰岛瘤细胞中的K+电流。

化合物

LY303511 hydrochloride
Cat.No: T84382
Synonym:
Target: Others
LY 303511 hydrochloride
Cat.No: T4423
Synonym: LY303511 hydrochloride
Target: Potassium Channel, TNF, mTOR
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