29
40
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37011 |
Boc-LRR-AMC
|
Others | Others |
Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. | |||
T8956 |
BC-1258
BC-1258 |
Apoptosis | Apoptosis |
BC-1258 是一种 F-box/LRR-重复蛋白 2激活剂,可诱导致瘤细胞凋亡,并显著抑制小鼠的肿瘤形成,还可以稳定和上调 FBXL2 水平。 | |||
T11878 |
LRRK2 inhibitor 1
|
LRRK2; CDK | Autophagy; Cell Cycle/Checkpoint |
LRRK2 inhibitor 1 是一种具有选择性和高效性的 LRRK2 抑制剂,IC50 为 13 nM。LRRK2 inhibitor 1 对 DCLK1 激酶具有抑制作用,IC 50 值为 2.61 nM。 | |||
T2246 |
LRRK2-IN-1
5,11-二氢-2-[[2-甲氧基-4-[[4-(4-甲基-1-哌嗪基)-1-哌啶基]羰基]苯基]氨基]-5,11-二甲基-6H-嘧啶并[4,5-B][1,4]苯并二氮杂卓-6-酮 |
Apoptosis; LRRK2; CDK | Apoptosis; Autophagy; Cell Cycle/Checkpoint |
LRRK2-IN-1 是一种选择性的LRRK2有效抑制剂,作用于 LRRK2 (G2019S) 和 LRRK2 (WT),IC50值分别为 6 nM 和 13 nM。 | |||
T73176 |
LRRK2-IN-7
|
LRRK2 | Autophagy |
LRRK2-IN-7 是一种具有选择性、CNS 渗透性和高效性的 LRRK2 激酶抑制剂(IC50:0.9 nM),可用于研究帕金森疾病。 | |||
T80550 |
N-myristoyl-RKRTLRRL
|
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
N-myristoyl-RKRTLRRL 抑制 PKC 底物结合,亦阻碍 Ca2+ 和磷脂酰丝氨酸(PS)依赖性组蛋白磷酸化,其中 IC50 为 5 μM;同样,N-myristoyl-RKRTLRRL 对组蛋白磷酸化的抑制作用中,IC50 为 80 μM。 | |||
TMAZ-0308A5 |
Anti-LRRC3 Monoclonal Antibody-AF555
|
||
Anti-LRRC3 Monoclonal Antibody-AF555 is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-AF555 can be used FACS. | |||
TMAZ-0076P |
Anti-LRRN1 Monoclonal Antibody-PE
|
||
Anti-LRRN1 Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-PE can be used FACS. | |||
TMAZ-0076B |
Anti-LRRN1 Monoclonal Antibody-Biotin
|
||
Anti-LRRN1 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-Biotin can be used FACS. | |||
T83737 |
LRRKtide TFA
Moesin (550-564),Membrane-organizing Extension Spike Protein (550-564) |
||
LRRKtide是一个针对富含亮氨酸重复激酶2 (LRRK2)的肽基底物,LRRK2是在帕金森病患者中频繁发生突变的酶,对应于膜组织扩展刺突蛋白(moesin)的550-564氨基酸。该化合物用于识别LRRK2的抑制剂。 | |||
T82929 |
AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG
|
||
AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG 促进骨化作用。该化合物适用于研究成骨缺陷或骨矿物质密度(BMD)降低相关疾病,如骨质疏松症。 | |||
T63620 |
LRRK2-IN-3
|
Others | Others |
LRRK2-IN-3 是有效的、选择性的、口服具有活力的、能够透过血脑屏障的 LRRK2 抑制剂,在 hPBMCs 中的 IC50 值为 0.6 nM。LRRK2-IN-3 能够用于研究帕金森氏病。 | |||
TMAZ-0308A4 |
Anti-LRRC3 Monoclonal Antibody-AF488
|
||
Anti-LRRC3 Monoclonal Antibody-AF488 is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-AF488 can be used FACS. | |||
TMAZ-0076A5 |
Anti-LRRN1 Monoclonal Antibody-AF555
|
||
Anti-LRRN1 Monoclonal Antibody-AF555 is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-AF555 can be used FACS. | |||
T63057 |
LRRK2-IN-5
|
Others | Others |
LRRK2-IN-5 (compound 25) 是一种口服具有活力的、能透过血脑屏障的、选择性富含亮氨酸重复蛋白激酶 2 基因 (LRRK2) 抑制剂,对 GS LRRK2 (IC50: 1.2 μM) 和 WT LRRK2 (IC50: 16 μM) 具有抑制作用。LRRK2-IN-5 能够抑制 LRRK2 Ser1292 和 Ser925 的自磷酸化。 | |||
T72421 |
LRRK2/NUAK1/TYK2-IN-1
|
Others | Others |
LRRK2/NUAK1/TYK2-IN-1 (conpound 226) 显示出对 LRRK2(Wt)、LRRK2(G2019)、TYK2和 NUAK1的抑制活性,其IC50值小于 10 nM。LRRK2/NUAK1/TYK2-IN-1 可用于自身免疫性疾病研究。 | |||
TMAZ-0308A |
Anti-LRRC3 Monoclonal Antibody-APC
|
||
Anti-LRRC3 Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-APC can be used FACS. | |||
TMAZ-0076A |
Anti-LRRN1 Monoclonal Antibody-APC
|
||
Anti-LRRN1 Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-APC can be used FACS. | |||
T82170 |
HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2
|
||
HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2 为一种抗炎活性肽类化合物。 | |||
T62871 |
LRRK2-IN-6
|
Others | Others |
LRRK2-IN-6 (compound 22) 是一种具有血脑屏障通透性的、口服具有活力的、选择性富含亮氨酸重复蛋白激酶 2 基因 (LRRK2) 抑制剂,能够抑制 GS LRRK2 (IC50: 4.6 μM) 和 WT LRRK2 (IC50: 49 μM)。LRRK2-IN-6 对 LRRK2 Ser1292 和 Ser925 的自磷酸化表现出抑制作用。 | |||
T63621 |
LRRK2-IN-4
|
Others | Others |
LRRK2-IN-4 是有效的、选择性的、口服具有活力的、能够透过血脑屏障的富含亮氨酸的重复激酶 2 (LRRK2) 抑制剂,其 IC50 值为 2.6 nM。LRRK2-IN-3 对帕金森氏病表现出研究潜力。 | |||
T63824 |
LRRK2-IN-2
|
Others | Others |
LRRK2-IN-2 是选择性的、有效的、能够透过血脑屏障的、口服具有活力的 LRRK2 抑制剂 (IC50: 0.6 nM)。LRRK2-IN-2 能够用于研究帕金森氏病。 | |||
TMAZ-0308P |
Anti-LRRC3 Monoclonal Antibody-PE
|
||
Anti-LRRC3 Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-PE can be used FACS. | |||
TMAZ-0076A4 |
Anti-LRRN1 Monoclonal Antibody-AF488
|
||
Anti-LRRN1 Monoclonal Antibody-AF488 is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-AF488 can be used FACS. | |||
TMAZ-0076A6 |
Anti-LRRN1 Monoclonal Antibody-AF647
|
||
Anti-LRRN1 Monoclonal Antibody-AF647 is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-AF647 can be used FACS. | |||
TMAZ-0308A6 |
Anti-LRRC3 Monoclonal Antibody-AF647
|
||
Anti-LRRC3 Monoclonal Antibody-AF647 is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-AF647 can be used FACS. | |||
T79746 |
LRRK2-IN-10
|
LRRK2 | Autophagy |
LRRK2-IN-10 (compound 34) 是一款高效、选择性针对G2019S突变的、可以穿透血脑屏障的G2019S-LRRK2激酶抑制剂,对G2019S-LRRK2 pS935和G2019S-LRRK2 pS1292显示出强效的抑制作用,其半抑制浓度(IC50)分别为11 nM和5.2 nM。该化合物对于帕金森病研究具备重要的应用价值。 | |||
TMAZ-0308B |
Anti-LRRC3 Monoclonal Antibody-Biotin
|
||
Anti-LRRC3 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-Biotin can be used FACS. | |||
T8553 |
BC-1471
|
Others | Others |
BC-1471 是STAM 结合蛋白(STAMBP)去泛素酶抑制剂。BC-1471 抑制 NALP7(NACHT, LRR 和 PYD 结构域蛋白 7)的炎症小体活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00470 |
PSKR Protein, Daucus carota, Recombinant (His)
PSKR,Phytosulfokine LRR receptor kinase 1,Phytosulf... |
Daucus carota | P. pastoris (Yeast) |
PSKR Protein, Daucus carota, Recombinant (His) is expressed in Yeast. | |||
TMPH-01328 |
FBXL2 Protein, Human, Recombinant (His & SUMO)
FBXL2,F-box and leucine-rich repeat protein 2,F-box/LRR<... |
Human | E. coli |
FBXL2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.1 kDa and the accession number is Q9UKC9. | |||
TMPH-02131 |
SKP2 Protein, Human, Recombinant (His & SUMO)
S-phase kinase-associated protein 2,SKP2,F-box protein Skp2,... |
Human | E. coli |
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UB... | |||
TMPH-01739 |
NLRP3 Protein, Human, Recombinant (His)
PYRIN-containing APAF1-like protein 1,Caterpiller protein 1.... |
Human | E. coli |
NLRP3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.7 kDa and the accession number is Q96P20. | |||
TMPH-02796 |
NLRP3 Protein, Mouse, Recombinant (His & SUMO)
Nlrp3,Cold autoinflammatory syndrome 1 protein homolog,Mast ... |
Mouse | E. coli |
NLRP3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 34.2 kDa and the accession number is Q8R4B8. | |||
TMPH-01738 |
NLRP1 Protein, Human, Recombinant (GST)
Caspase recruitment domain-containing protein 7,Nucleotide-b... |
Human | E. coli |
NLRP1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.9 kDa and the accession number is Q9C000. | |||
TMPY-05085 |
LRRC32 Protein, Human, Recombinant (His)
leucine rich repeat containing 32,GARP,D11S833E |
Human | HEK293 Cells |
LRRC32 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7. | |||
TMPY-04333 |
LRRC15 Protein, Human, Recombinant (hFc)
leucine rich repeat containing 15,LIB |
Human | HEK293 Cells |
LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1. | |||
TMPJ-00338 |
LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated
Leucine-rich repeat-containing protein 15,LIB,LRRC1... |
Human | HEK293 Cells |
The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions used for molecular recognition process such as cell adhesion, signal transduction, DNA repair, and RNA processing. The LRRC15 is also a transmembrane protein demonstrated to play important roles in cancer. LRRC15 expression was notably increased 4.6-fold in cariesdiseased pulpal t... | |||
TMPJ-01222 |
LRRC25 Protein, Human, Recombinant (His)
Leucine-rich repeat-containing protein 25,MAPA,Monocyte and ... |
Human | HEK293 Cells |
Leucine-rich repeat-containing protein 25(LRRC25) is a single-pass type I membrane protein and contains 3 LRR (leucine-rich) repeats. The protein expressed in plasmacytoid dendritic cells (PDC), monocyte-derived dendritic cells (MDDC), granulocytes, monocytes, B-lymphocytes, peripheral blood leukocytes, spleen, bone marrow, and, to a lesser extent, lymph nodes, fetal liver, and appendix but not in thymus. The protein may be involved in the activation of cells of innate and acquired immunity. | |||
TMPY-02491 |
LRRN3 Protein, Human, Recombinant (His)
NLRR3,FIGLER5,leucine rich repeat neuronal 3,NL... |
Human | Baculovirus Insect Cells |
Leucine-rich repeat neuronal protein 3, also known as neuronal leucine-rich repeat protein 3 (NLRR-3), is a member of the leucine-rich (LRR) family whose members have significant functions in neural development. Leucine-rich repeats are short sequence motifs present in some proteins with diverse functions and cellular locations. All proteins containing these repeats are thought to be involved in protein-protein interactions. The crystal structure of ribonuclease inhibitor protein has revealed th... | |||
TMPY-06148 |
LRRC15 Protein, Human, Recombinant (His)
leucine rich repeat containing 15,LIB |
Human | HEK293 Cells |
LRRC15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is Q8TF66-1. | |||
TMPY-05375 |
LRRC32 Protein, Human, Recombinant (His), Biotinylated
leucine rich repeat containing 32,D11S833E,GARP |
Human | HEK293 Cells |
LRRC32 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7. | |||
TMPK-01070 |
LRRC15 Protein, Mouse, Recombinant (His)
LIB,LRRC15 |
Mouse | HEK293 Cells |
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote... | |||
TMPK-00338 |
LRRC15 Protein, Human, Recombinant (His & Avi)
LRRC15,LIB |
Human | CHO Cells |
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote... | |||
TMPK-01309 |
LRRC15 Protein, Canine, Recombinant (His)
LIB,LRRC15 |
Canine | HEK293 Cells |
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote... | |||
TMPK-01030 |
LRRN1 Protein, Mouse, Recombinant (His)
Neuronal leucine-rich repeat protein 1,LRN,NLRR1,N<... |
Mouse | HEK293 Cells |
Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction between midbrain and hindbrain compartments. Lrrn1 also regulates the glycosyltransferase Lunatic Fringe, a modulator of Notch signalling, maintaining its expression in midbrain cells which is instrumental in MHB boundary formation. | |||
TMPY-00088 |
LRRC3B Protein, Human, Recombinant (His)
leucine rich repeat containing 3B,LRP15 |
Human | HEK293 Cells |
LRRC3B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is A1LNH5. | |||
TMPY-05803 |
NGL-1/LRRC4C Protein, Human, Recombinant (His)
NGL-1,leucine rich repeat containing 4C,NGL1 |
Human | HEK293 Cells |
NGL-1/LRRC4C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.51 kDa and the accession number is Q9HCJ2. | |||
TMPY-06910 |
LRRC15 Protein, Cynomolgus, Recombinant (His)
leucine rich repeat containing 15 |
Cynomolgus | HEK293 Cells |
LRRC15 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.28 kDa and the accession number is G7NYR2. | |||
TMPY-06703 |
LRRC32 Protein, Mouse, Recombinant (hFc)
leucine rich repeat containing 32,D11S833Eh,Garp,D7H11S833E,... |
Mouse | HEK293 Cells |
LRRC32 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.38 kDa and the accession number is G3XA59. | |||
TMPY-04823 |
LRRTM2 Protein, Human, Recombinant (His)
leucine rich repeat transmembrane neuronal 2 |
Human | HEK293 Cells |
LRRTM2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is O43300. | |||
TMPJ-00364 |
LRRC32 Protein, Human, Recombinant (hFc)
D11S833E,GARPGarpin,GARP,Garpin |
Human | HEK293 Cells |
Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naïve T cell proliferation. LRRC32 is widely expressed during embryogenesis and on adult platelets. Human LRR... | |||
TMPY-05437 |
NGL-1/LRRC4C Protein, Mouse, Recombinant (His)
NGL-1,leucine rich repeat containing 4C,6430556C10Rik |
Mouse | HEK293 Cells |
NGL-1/LRRC4C Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.5 kDa and the accession number is BAC27884.1. | |||
TMPY-04856 |
LRRTM2 Protein, Human, Recombinant (hFc)
leucine rich repeat transmembrane neuronal 2 |
Human | HEK293 Cells |
LRRTM2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.2 kDa and the accession number is O43300. | |||
TMPY-06705 |
LRRC32 Protein, Mouse, Recombinant (His)
Garp,AI426318,leucine rich repeat containing 32,D11S833Eh,D7... |
Mouse | HEK293 Cells |
LRRC32 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68.10 kDa and the accession number is G3XA59. | |||
TMPK-01380 |
LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
LIB,EGM_11224,LRRC15 |
Cynomolgus,Rhesus | HEK293 Cells |
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote... | |||
TMPY-06919 |
LRRC15 Protein, Mouse, Recombinant (His & Avi), Biotinylated
LIB,leucine rich repeat containing 15,5430427N11Rik |
Mouse | HEK293 Cells |
LRRC15 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 60.74 kDa and the accession number is NP_083249.1. | |||
TMPY-01655 |
LRRTM4 Protein, Human, Recombinant (His)
leucine rich repeat transmembrane neuronal 4 |
Human | HEK293 Cells |
LRRTM4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q86VH4-1. | |||
TMPY-00353 |
LRRC3B Protein, Human, Recombinant (hFc)
LRP15,leucine rich repeat containing 3B |
Human | HEK293 Cells |
LRRC3B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.7 kDa and the accession number is A1LNH5. | |||
TMPY-00068 |
LRRTM4 Protein, Mouse, Recombinant (His)
leucine rich repeat transmembrane neuronal 4,A230052N11,7530... |
Mouse | HEK293 Cells |
LRRTM4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.4 kDa and the accession number is Q80XG9-2. | |||
TMPJ-00231 |
LRG1 Protein, Human, Recombinant (hFc & His)
LRG and LRG1,Leucine-rich alpha-2-glycoprotein,Leucine-rich ... |
Human | HEK293 Cells |
LRG1 is a secreted protein and contains eight LRR repeats and one LRRCT domain, It can be expressed during granulocyte differentiation. LRG1 has been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Levels of the LRG protein are markedly elevated in acute appendicitis and therefore could be used as a diagnostic aid. | |||
TMPY-03063 |
SLITRK6 Protein, Human, Recombinant (His)
SLIT and NTRK like family member 6,SLITRK6,DFNMYP |
Human | HEK293 Cells |
SLITRK6 belongs to the SLITRK family. Members of this family share two conserved leucine-rich repeat domains in the extracellular domain. SLITRK6 contains 11 LRR (leucine-rich) repeats, 2 LRRCT domains and 2 LRRNT domains. Expression of SlITRK proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. SLITRK6 is highly expressed in putamen with no expression in cerebral cortex. It also can be detected in adult and fetal lung and fetal liver. It can sup... | |||
TMPJ-00924 |
Decorin Protein, Mouse, Recombinant (His)
PG40,Bone proteoglycan II,Decorin,Dcn,PG-S2 |
Mouse | HEK293 Cells |
Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a guardian from the matrix. Mature human Decorin contains 12 tandem LRR and shares 80% and 78% aa sequence identity with mouse and rat Decorin, respectively. Decorin embraces numerous functions including: regulation of collagen fibrillogenesis, hepatic carcinogenesis, fetal membrane a... | |||
TMPY-03058 |
SLITL2/VASN Protein, Human, Recombinant (His)
SLITL2,vasorin |
Human | HEK293 Cells |
Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular smooth muscle cells, and that its expression is developmentally regulated. vasorin It directly binds to transforming growth factor (TGF)-β and attenuates TGF-β signaling in vitro. This suggests that down-regulation of vasorin expression contributes to neointimal formation after ... | |||
TMPY-02484 |
SLITRK4 Protein, Human, Recombinant (His)
DKFZp547M2010,SLIT and NTRK like family member 4 |
Human | HEK293 Cells |
SLIT and NTRK-like family proteins 4 is a member of the SLIT and NTRK-like family. This protein is characterized as an integral membrane protein that has two leucine-rich repeat (LRR) domains and a carboxy-terminal domain that is partially similar to SLIT protein and TRK Neurotrophin There are six members in this family: SLITRK1, SLITRK2, SLITRK3, SLITRK4, SLITRK5, and SLITRK6. Their expression was detected mainly in the brain, but the expression profile of each SLITRK was unique. Each of these ... | |||
TMPJ-00277 |
NgR3 Protein, Human, Recombinant (His)
NGRL2,Nogo Receptor-Like 2,Reticulon-4 Receptor-Like 1,NgR3,... |
Human | HEK293 Cells |
Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration ... | |||
TMPY-01438 |
FLRT3 Protein, Human, Recombinant (His)
fibronectin leucine rich transmembrane protein 3,HH21 |
Human | HEK293 Cells |
Leucine-rich repeat transmembrane protein FLRT3, also known as Fibronectin-like domain-containing leucine-rich transmembrane protein 3, and FLRT3, is a single-pass type I membrane protein which belongs to the fibronectin leucine rich transmembrane protein (FLRT) family. FLRT3 contains one fibronectin type-III domain and ten LRR (leucine-rich) repeats and is expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart. It has a provocative expression pattern during somi... | |||
TMPJ-00320 |
AMIGO2 Protein, Human, Recombinant (hFc)
DEGA,AMIGO-2,AMIGO2,ALI1,Alivin-1,Amphoterin-Induced Protein... |
Human | HEK293 Cells |
Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2... | |||
TMPY-02032 |
FLRT1 Protein, Human, Recombinant (His)
SPG68,fibronectin leucine rich transmembrane protein 1 |
Human | HEK293 Cells |
The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT1 is expressed in kidney and brain, which is a target for tyrosine phosphorylation mediated by FGFR1 and implicates a non-receptor Src family kinase (SFK). All FLRTs can interact with FGFR1 and FLRTs can be induced by the activation of FGF signalling by FGF-2. The phosphorylation ... |