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Search Results for " lrr "
Targets Recommended: LRRK2 Others

29

抑制剂 & 化合物

40

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T37011 Boc-LRR-AMC

Others Others
Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
T8956 BC-​1258

BC-1258

Apoptosis Apoptosis
BC-1258 是一种 F-box/LRR-重复蛋白 2激活剂,可诱导致瘤细胞凋亡,并显著抑制小鼠的肿瘤形成,还可以稳定和上调 FBXL2 水平。
T11878 LRRK2 inhibitor 1

LRRK2; CDK Autophagy; Cell Cycle/Checkpoint
LRRK2 inhibitor 1 是一种具有选择性和高效性的 LRRK2 抑制剂,IC50 为 13 nM。LRRK2 inhibitor 1 对 DCLK1 激酶具有抑制作用,IC 50 值为 2.61 nM。
T2246 LRRK2-IN-1

5,11-二氢-2-[[2-甲氧基-4-[[4-(4-甲基-1-哌嗪基)-1-哌啶基]羰基]苯基]氨基]-5,11-二甲基-6H-嘧啶并[4,5-B][1,4]苯并二氮杂卓-6-酮

Apoptosis; LRRK2; CDK Apoptosis; Autophagy; Cell Cycle/Checkpoint
LRRK2-IN-1 是一种选择性的LRRK2有效抑制剂,作用于 LRRK2 (G2019S) 和 LRRK2 (WT),IC50值分别为 6 nM 和 13 nM。
T73176 LRRK2-IN-7

LRRK2 Autophagy
LRRK2-IN-7 是一种具有选择性、CNS 渗透性和高效性的 LRRK2 激酶抑制剂(IC50:0.9 nM),可用于研究帕金森疾病。
T80550 N-myristoyl-RKRTLRRL

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
N-myristoyl-RKRTLRRL 抑制 PKC 底物结合,亦阻碍 Ca2+ 和磷脂酰丝氨酸(PS)依赖性组蛋白磷酸化,其中 IC50 为 5 μM;同样,N-myristoyl-RKRTLRRL 对组蛋白磷酸化的抑制作用中,IC50 为 80 μM。
TMAZ-0308A5 Anti-LRRC3 Monoclonal Antibody-AF555

Anti-LRRC3 Monoclonal Antibody-AF555 is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-AF555 can be used FACS.
TMAZ-0076P Anti-LRRN1 Monoclonal Antibody-PE

Anti-LRRN1 Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-PE can be used FACS.
TMAZ-0076B Anti-LRRN1 Monoclonal Antibody-Biotin

Anti-LRRN1 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-Biotin can be used FACS.
T83737 LRRKtide TFA

Moesin (550-564),Membrane-organizing Extension Spike Protein (550-564)

LRRKtide是一个针对富含亮氨酸重复激酶2 (LRRK2)的肽基底物,LRRK2是在帕金森病患者中频繁发生突变的酶,对应于膜组织扩展刺突蛋白(moesin)的550-564氨基酸。该化合物用于识别LRRK2的抑制剂。
T82929 AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG

AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG 促进骨化作用。该化合物适用于研究成骨缺陷或骨矿物质密度(BMD)降低相关疾病,如骨质疏松症。
T63620 LRRK2-IN-3

Others Others
LRRK2-IN-3 是有效的、选择性的、口服具有活力的、能够透过血脑屏障的 LRRK2 抑制剂,在 hPBMCs 中的 IC50 值为 0.6 nM。LRRK2-IN-3 能够用于研究帕金森氏病。
TMAZ-0308A4 Anti-LRRC3 Monoclonal Antibody-AF488

Anti-LRRC3 Monoclonal Antibody-AF488 is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-AF488 can be used FACS.
TMAZ-0076A5 Anti-LRRN1 Monoclonal Antibody-AF555

Anti-LRRN1 Monoclonal Antibody-AF555 is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-AF555 can be used FACS.
T63057 LRRK2-IN-5

Others Others
LRRK2-IN-5 (compound 25) 是一种口服具有活力的、能透过血脑屏障的、选择性富含亮氨酸重复蛋白激酶 2 基因 (LRRK2) 抑制剂,对 GS LRRK2 (IC50: 1.2 μM) 和 WT LRRK2 (IC50: 16 μM) 具有抑制作用。LRRK2-IN-5 能够抑制 LRRK2 Ser1292 和 Ser925 的自磷酸化。
T72421 LRRK2/NUAK1/TYK2-IN-1

Others Others
LRRK2/NUAK1/TYK2-IN-1 (conpound 226) 显示出对 LRRK2(Wt)、LRRK2(G2019)、TYK2和 NUAK1的抑制活性,其IC50值小于 10 nM。LRRK2/NUAK1/TYK2-IN-1 可用于自身免疫性疾病研究。
TMAZ-0308A Anti-LRRC3 Monoclonal Antibody-APC

Anti-LRRC3 Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-APC can be used FACS.
TMAZ-0076A Anti-LRRN1 Monoclonal Antibody-APC

Anti-LRRN1 Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-APC can be used FACS.
T82170 HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2

HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2 为一种抗炎活性肽类化合物。
T62871 LRRK2-IN-6

Others Others
LRRK2-IN-6 (compound 22) 是一种具有血脑屏障通透性的、口服具有活力的、选择性富含亮氨酸重复蛋白激酶 2 基因 (LRRK2) 抑制剂,能够抑制 GS LRRK2 (IC50: 4.6 μM) 和 WT LRRK2 (IC50: 49 μM)。LRRK2-IN-6 对 LRRK2 Ser1292 和 Ser925 的自磷酸化表现出抑制作用。
T63621 LRRK2-IN-4

Others Others
LRRK2-IN-4 是有效的、选择性的、口服具有活力的、能够透过血脑屏障的富含亮氨酸的重复激酶 2 (LRRK2) 抑制剂,其 IC50 值为 2.6 nM。LRRK2-IN-3 对帕金森氏病表现出研究潜力。
T63824 LRRK2-IN-2

Others Others
LRRK2-IN-2 是选择性的、有效的、能够透过血脑屏障的、口服具有活力的 LRRK2 抑制剂 (IC50: 0.6 nM)。LRRK2-IN-2 能够用于研究帕金森氏病。
TMAZ-0308P Anti-LRRC3 Monoclonal Antibody-PE

Anti-LRRC3 Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-PE can be used FACS.
TMAZ-0076A4 Anti-LRRN1 Monoclonal Antibody-AF488

Anti-LRRN1 Monoclonal Antibody-AF488 is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-AF488 can be used FACS.
TMAZ-0076A6 Anti-LRRN1 Monoclonal Antibody-AF647

Anti-LRRN1 Monoclonal Antibody-AF647 is a biotin-conjugated humanized rabbit antibody targeting LRRN1. Anti-LRRN1 Monoclonal Antibody-AF647 can be used FACS.
TMAZ-0308A6 Anti-LRRC3 Monoclonal Antibody-AF647

Anti-LRRC3 Monoclonal Antibody-AF647 is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-AF647 can be used FACS.
T79746 LRRK2-IN-10

LRRK2 Autophagy
LRRK2-IN-10 (compound 34) 是一款高效、选择性针对G2019S突变的、可以穿透血脑屏障的G2019S-LRRK2激酶抑制剂,对G2019S-LRRK2 pS935和G2019S-LRRK2 pS1292显示出强效的抑制作用,其半抑制浓度(IC50)分别为11 nM和5.2 nM。该化合物对于帕金森病研究具备重要的应用价值。
TMAZ-0308B Anti-LRRC3 Monoclonal Antibody-Biotin

Anti-LRRC3 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting LRRC3. Anti-LRRC3 Monoclonal Antibody-Biotin can be used FACS.
T8553 BC-1471

Others Others
BC-1471 是STAM 结合蛋白(STAMBP)去泛素酶抑制剂。BC-1471 抑制 NALP7(NACHT, LRR 和 PYD 结构域蛋白 7)的炎症小体活性。

化合物

Boc-LRR-AMC
Cat.No: T37011
Synonym:
Target: Others
BC-​1258
Cat.No: T8956
Synonym: BC-1258
Target: Apoptosis
LRRK2 inhibitor 1
Cat.No: T11878
Synonym:
Target: LRRK2, CDK
LRRK2-IN-1
Cat.No: T2246
Synonym: 5,11-二氢-2-[[2-甲氧基-4-[[4-(4-甲基-1-哌嗪基)-1-哌啶基]羰基]苯基]氨基]-5,11-二甲基-6H-嘧啶并[4,5-B][1,4]苯并二氮杂卓-6-酮
Target: Apoptosis, LRRK2, CDK
LRRK2-IN-7
Cat.No: T73176
Synonym:
Target: LRRK2
N-myristoyl-RKRTLRRL
Cat.No: T80550
Synonym:
Target: PKC
Anti-LRRC3 Monoclonal Antibody-AF555
Cat.No: TMAZ-0308A5
Synonym:
Target:
Anti-LRRN1 Monoclonal Antibody-PE
Cat.No: TMAZ-0076P
Synonym:
Target:
Anti-LRRN1 Monoclonal Antibody-Biotin
Cat.No: TMAZ-0076B
Synonym:
Target:
LRRKtide TFA
Cat.No: T83737
Synonym: Moesin (550-564),Membrane-organizing Extension Spike Protein (550-564)
Target:
AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG
Cat.No: T82929
Synonym:
Target:
LRRK2-IN-3
Cat.No: T63620
Synonym:
Target: Others
Anti-LRRC3 Monoclonal Antibody-AF488
Cat.No: TMAZ-0308A4
Synonym:
Target:
Anti-LRRN1 Monoclonal Antibody-AF555
Cat.No: TMAZ-0076A5
Synonym:
Target:
LRRK2-IN-5
Cat.No: T63057
Synonym:
Target: Others
LRRK2/NUAK1/TYK2-IN-1
Cat.No: T72421
Synonym:
Target: Others
Anti-LRRC3 Monoclonal Antibody-APC
Cat.No: TMAZ-0308A
Synonym:
Target:
Anti-LRRN1 Monoclonal Antibody-APC
Cat.No: TMAZ-0076A
Synonym:
Target:
HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2
Cat.No: T82170
Synonym:
Target:
LRRK2-IN-6
Cat.No: T62871
Synonym:
Target: Others
LRRK2-IN-4
Cat.No: T63621
Synonym:
Target: Others
LRRK2-IN-2
Cat.No: T63824
Synonym:
Target: Others
Anti-LRRC3 Monoclonal Antibody-PE
Cat.No: TMAZ-0308P
Synonym:
Target:
Anti-LRRN1 Monoclonal Antibody-AF488
Cat.No: TMAZ-0076A4
Synonym:
Target:
Anti-LRRN1 Monoclonal Antibody-AF647
Cat.No: TMAZ-0076A6
Synonym:
Target:
Anti-LRRC3 Monoclonal Antibody-AF647
Cat.No: TMAZ-0308A6
Synonym:
Target:
LRRK2-IN-10
Cat.No: T79746
Synonym:
Target: LRRK2
Anti-LRRC3 Monoclonal Antibody-Biotin
Cat.No: TMAZ-0308B
Synonym:
Target:
BC-1471
Cat.No: T8553
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-00470 PSKR Protein, Daucus carota, Recombinant (His)

PSKR,Phytosulfokine LRR receptor kinase 1,Phytosulf...

Daucus carota P. pastoris (Yeast)
PSKR Protein, Daucus carota, Recombinant (His) is expressed in Yeast.
TMPH-01328 FBXL2 Protein, Human, Recombinant (His & SUMO)

FBXL2,F-box and leucine-rich repeat protein 2,F-box/LRR<...

Human E. coli
FBXL2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.1 kDa and the accession number is Q9UKC9.
TMPH-02131 SKP2 Protein, Human, Recombinant (His & SUMO)

S-phase kinase-associated protein 2,SKP2,F-box protein Skp2,...

Human E. coli
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UB...
TMPH-01739 NLRP3 Protein, Human, Recombinant (His)

PYRIN-containing APAF1-like protein 1,Caterpiller protein 1....

Human E. coli
NLRP3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.7 kDa and the accession number is Q96P20.
TMPH-02796 NLRP3 Protein, Mouse, Recombinant (His & SUMO)

Nlrp3,Cold autoinflammatory syndrome 1 protein homolog,Mast ...

Mouse E. coli
NLRP3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 34.2 kDa and the accession number is Q8R4B8.
TMPH-01738 NLRP1 Protein, Human, Recombinant (GST)

Caspase recruitment domain-containing protein 7,Nucleotide-b...

Human E. coli
NLRP1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.9 kDa and the accession number is Q9C000.
TMPY-05085 LRRC32 Protein, Human, Recombinant (His)

leucine rich repeat containing 32,GARP,D11S833E

Human HEK293 Cells
LRRC32 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7.
TMPY-04333 LRRC15 Protein, Human, Recombinant (hFc)

leucine rich repeat containing 15,LIB

Human HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPJ-00338 LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated

Leucine-rich repeat-containing protein 15,LIB,LRRC1...

Human HEK293 Cells
The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions used for molecular recognition process such as cell adhesion, signal transduction, DNA repair, and RNA processing. The LRRC15 is also a transmembrane protein demonstrated to play important roles in cancer. LRRC15 expression was notably increased 4.6-fold in cariesdiseased pulpal t...
TMPJ-01222 LRRC25 Protein, Human, Recombinant (His)

Leucine-rich repeat-containing protein 25,MAPA,Monocyte and ...

Human HEK293 Cells
Leucine-rich repeat-containing protein 25(LRRC25) is a single-pass type I membrane protein and contains 3 LRR (leucine-rich) repeats. The protein expressed in plasmacytoid dendritic cells (PDC), monocyte-derived dendritic cells (MDDC), granulocytes, monocytes, B-lymphocytes, peripheral blood leukocytes, spleen, bone marrow, and, to a lesser extent, lymph nodes, fetal liver, and appendix but not in thymus. The protein may be involved in the activation of cells of innate and acquired immunity.
TMPY-02491 LRRN3 Protein, Human, Recombinant (His)

NLRR3,FIGLER5,leucine rich repeat neuronal 3,NL...

Human Baculovirus Insect Cells
Leucine-rich repeat neuronal protein 3, also known as neuronal leucine-rich repeat protein 3 (NLRR-3), is a member of the leucine-rich (LRR) family whose members have significant functions in neural development. Leucine-rich repeats are short sequence motifs present in some proteins with diverse functions and cellular locations. All proteins containing these repeats are thought to be involved in protein-protein interactions. The crystal structure of ribonuclease inhibitor protein has revealed th...
TMPY-06148 LRRC15 Protein, Human, Recombinant (His)

leucine rich repeat containing 15,LIB

Human HEK293 Cells
LRRC15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is Q8TF66-1.
TMPY-05375 LRRC32 Protein, Human, Recombinant (His), Biotinylated

leucine rich repeat containing 32,D11S833E,GARP

Human HEK293 Cells
LRRC32 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7.
TMPK-01070 LRRC15 Protein, Mouse, Recombinant (His)

LIB,LRRC15

Mouse HEK293 Cells
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation.  LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote...
TMPK-00338 LRRC15 Protein, Human, Recombinant (His & Avi)

LRRC15,LIB

Human CHO Cells
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation.  LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote...
TMPK-01309 LRRC15 Protein, Canine, Recombinant (His)

LIB,LRRC15

Canine HEK293 Cells
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation.  LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote...
TMPK-01030 LRRN1 Protein, Mouse, Recombinant (His)

Neuronal leucine-rich repeat protein 1,LRN,NLRR1,N<...

Mouse HEK293 Cells
Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction between midbrain and hindbrain compartments. Lrrn1 also regulates the glycosyltransferase Lunatic Fringe, a modulator of Notch signalling, maintaining its expression in midbrain cells which is instrumental in MHB boundary formation.
TMPY-00088 LRRC3B Protein, Human, Recombinant (His)

leucine rich repeat containing 3B,LRP15

Human HEK293 Cells
LRRC3B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is A1LNH5.
TMPY-05803 NGL-1/LRRC4C Protein, Human, Recombinant (His)

NGL-1,leucine rich repeat containing 4C,NGL1

Human HEK293 Cells
NGL-1/LRRC4C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.51 kDa and the accession number is Q9HCJ2.
TMPY-06910 LRRC15 Protein, Cynomolgus, Recombinant (His)

leucine rich repeat containing 15

Cynomolgus HEK293 Cells
LRRC15 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.28 kDa and the accession number is G7NYR2.
TMPY-06703 LRRC32 Protein, Mouse, Recombinant (hFc)

leucine rich repeat containing 32,D11S833Eh,Garp,D7H11S833E,...

Mouse HEK293 Cells
LRRC32 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.38 kDa and the accession number is G3XA59.
TMPY-04823 LRRTM2 Protein, Human, Recombinant (His)

leucine rich repeat transmembrane neuronal 2

Human HEK293 Cells
LRRTM2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is O43300.
TMPJ-00364 LRRC32 Protein, Human, Recombinant (hFc)

D11S833E,GARPGarpin,GARP,Garpin

Human HEK293 Cells
Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naïve T cell proliferation. LRRC32 is widely expressed during embryogenesis and on adult platelets. Human LRR...
TMPY-05437 NGL-1/LRRC4C Protein, Mouse, Recombinant (His)

NGL-1,leucine rich repeat containing 4C,6430556C10Rik

Mouse HEK293 Cells
NGL-1/LRRC4C Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.5 kDa and the accession number is BAC27884.1.
TMPY-04856 LRRTM2 Protein, Human, Recombinant (hFc)

leucine rich repeat transmembrane neuronal 2

Human HEK293 Cells
LRRTM2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.2 kDa and the accession number is O43300.
TMPY-06705 LRRC32 Protein, Mouse, Recombinant (His)

Garp,AI426318,leucine rich repeat containing 32,D11S833Eh,D7...

Mouse HEK293 Cells
LRRC32 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68.10 kDa and the accession number is G3XA59.
TMPK-01380 LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

LIB,EGM_11224,LRRC15

Cynomolgus,Rhesus HEK293 Cells
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation.  LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Prote...
TMPY-06919 LRRC15 Protein, Mouse, Recombinant (His & Avi), Biotinylated

LIB,leucine rich repeat containing 15,5430427N11Rik

Mouse HEK293 Cells
LRRC15 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 60.74 kDa and the accession number is NP_083249.1.
TMPY-01655 LRRTM4 Protein, Human, Recombinant (His)

leucine rich repeat transmembrane neuronal 4

Human HEK293 Cells
LRRTM4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q86VH4-1.
TMPY-00353 LRRC3B Protein, Human, Recombinant (hFc)

LRP15,leucine rich repeat containing 3B

Human HEK293 Cells
LRRC3B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.7 kDa and the accession number is A1LNH5.
TMPY-00068 LRRTM4 Protein, Mouse, Recombinant (His)

leucine rich repeat transmembrane neuronal 4,A230052N11,7530...

Mouse HEK293 Cells
LRRTM4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.4 kDa and the accession number is Q80XG9-2.
TMPJ-00231 LRG1 Protein, Human, Recombinant (hFc & His)

LRG and LRG1,Leucine-rich alpha-2-glycoprotein,Leucine-rich ...

Human HEK293 Cells
LRG1 is a secreted protein and contains eight LRR repeats and one LRRCT domain, It can be expressed during granulocyte differentiation. LRG1 has been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Levels of the LRG protein are markedly elevated in acute appendicitis and therefore could be used as a diagnostic aid.
TMPY-03063 SLITRK6 Protein, Human, Recombinant (His)

SLIT and NTRK like family member 6,SLITRK6,DFNMYP

Human HEK293 Cells
SLITRK6 belongs to the SLITRK family. Members of this family share two conserved leucine-rich repeat domains in the extracellular domain. SLITRK6 contains 11 LRR (leucine-rich) repeats, 2 LRRCT domains and 2 LRRNT domains. Expression of SlITRK proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. SLITRK6 is highly expressed in putamen with no expression in cerebral cortex. It also can be detected in adult and fetal lung and fetal liver. It can sup...
TMPJ-00924 Decorin Protein, Mouse, Recombinant (His)

PG40,Bone proteoglycan II,Decorin,Dcn,PG-S2

Mouse HEK293 Cells
Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a guardian from the matrix. Mature human Decorin contains 12 tandem LRR and shares 80% and 78% aa sequence identity with mouse and rat Decorin, respectively. Decorin embraces numerous functions including: regulation of collagen fibrillogenesis, hepatic carcinogenesis, fetal membrane a...
TMPY-03058 SLITL2/VASN Protein, Human, Recombinant (His)

SLITL2,vasorin

Human HEK293 Cells
Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular smooth muscle cells, and that its expression is developmentally regulated. vasorin It directly binds to transforming growth factor (TGF)-β and attenuates TGF-β signaling in vitro. This suggests that down-regulation of vasorin expression contributes to neointimal formation after ...
TMPY-02484 SLITRK4 Protein, Human, Recombinant (His)

DKFZp547M2010,SLIT and NTRK like family member 4

Human HEK293 Cells
SLIT and NTRK-like family proteins 4 is a member of the SLIT and NTRK-like family. This protein is characterized as an integral membrane protein that has two leucine-rich repeat (LRR) domains and a carboxy-terminal domain that is partially similar to SLIT protein and TRK Neurotrophin There are six members in this family: SLITRK1, SLITRK2, SLITRK3, SLITRK4, SLITRK5, and SLITRK6. Their expression was detected mainly in the brain, but the expression profile of each SLITRK was unique. Each of these ...
TMPJ-00277 NgR3 Protein, Human, Recombinant (His)

NGRL2,Nogo Receptor-Like 2,Reticulon-4 Receptor-Like 1,NgR3,...

Human HEK293 Cells
Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration ...
TMPY-01438 FLRT3 Protein, Human, Recombinant (His)

fibronectin leucine rich transmembrane protein 3,HH21

Human HEK293 Cells
Leucine-rich repeat transmembrane protein FLRT3, also known as Fibronectin-like domain-containing leucine-rich transmembrane protein 3, and FLRT3, is a single-pass type I membrane protein which belongs to the fibronectin leucine rich transmembrane protein (FLRT) family. FLRT3 contains one fibronectin type-III domain and ten LRR (leucine-rich) repeats and is expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart. It has a provocative expression pattern during somi...
TMPJ-00320 AMIGO2 Protein, Human, Recombinant (hFc)

DEGA,AMIGO-2,AMIGO2,ALI1,Alivin-1,Amphoterin-Induced Protein...

Human HEK293 Cells
Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2...
TMPY-02032 FLRT1 Protein, Human, Recombinant (His)

SPG68,fibronectin leucine rich transmembrane protein 1

Human HEK293 Cells
The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT1 is expressed in kidney and brain, which is a target for tyrosine phosphorylation mediated by FGFR1 and implicates a non-receptor Src family kinase (SFK). All FLRTs can interact with FGFR1 and FLRTs can be induced by the activation of FGF signalling by FGF-2. The phosphorylation ...

重组蛋白

PSKR Protein, Daucus carota, Recombinant (His)
Cat.No: TMPH-00470
Species: Daucus carota
Expression System: P. pastoris (Yeast)
FBXL2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01328
Species: Human
Expression System: E. coli
SKP2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02131
Species: Human
Expression System: E. coli
NLRP3 Protein, Human, Recombinant (His)
Cat.No: TMPH-01739
Species: Human
Expression System: E. coli
NLRP3 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02796
Species: Mouse
Expression System: E. coli
NLRP1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01738
Species: Human
Expression System: E. coli
LRRC32 Protein, Human, Recombinant (His)
Cat.No: TMPY-05085
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04333
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00338
Species: Human
Expression System: HEK293 Cells
LRRC25 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01222
Species: Human
Expression System: HEK293 Cells
LRRN3 Protein, Human, Recombinant (His)
Cat.No: TMPY-02491
Species: Human
Expression System: Baculovirus Insect Cells
LRRC15 Protein, Human, Recombinant (His)
Cat.No: TMPY-06148
Species: Human
Expression System: HEK293 Cells
LRRC32 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05375
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01070
Species: Mouse
Expression System: HEK293 Cells
LRRC15 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00338
Species: Human
Expression System: CHO Cells
LRRC15 Protein, Canine, Recombinant (His)
Cat.No: TMPK-01309
Species: Canine
Expression System: HEK293 Cells
LRRN1 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01030
Species: Mouse
Expression System: HEK293 Cells
LRRC3B Protein, Human, Recombinant (His)
Cat.No: TMPY-00088
Species: Human
Expression System: HEK293 Cells
NGL-1/LRRC4C Protein, Human, Recombinant (His)
Cat.No: TMPY-05803
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-06910
Species: Cynomolgus
Expression System: HEK293 Cells
LRRC32 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-06703
Species: Mouse
Expression System: HEK293 Cells
LRRTM2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04823
Species: Human
Expression System: HEK293 Cells
LRRC32 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00364
Species: Human
Expression System: HEK293 Cells
NGL-1/LRRC4C Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05437
Species: Mouse
Expression System: HEK293 Cells
LRRTM2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04856
Species: Human
Expression System: HEK293 Cells
LRRC32 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06705
Species: Mouse
Expression System: HEK293 Cells
LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Cat.No: TMPK-01380
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
LRRC15 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06919
Species: Mouse
Expression System: HEK293 Cells
LRRTM4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01655
Species: Human
Expression System: HEK293 Cells
LRRC3B Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00353
Species: Human
Expression System: HEK293 Cells
LRRTM4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00068
Species: Mouse
Expression System: HEK293 Cells
LRG1 Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00231
Species: Human
Expression System: HEK293 Cells
SLITRK6 Protein, Human, Recombinant (His)
Cat.No: TMPY-03063
Species: Human
Expression System: HEK293 Cells
Decorin Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00924
Species: Mouse
Expression System: HEK293 Cells
SLITL2/VASN Protein, Human, Recombinant (His)
Cat.No: TMPY-03058
Species: Human
Expression System: HEK293 Cells
SLITRK4 Protein, Human, Recombinant (His)
Cat.No: TMPY-02484
Species: Human
Expression System: HEK293 Cells
NgR3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00277
Species: Human
Expression System: HEK293 Cells
FLRT3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01438
Species: Human
Expression System: HEK293 Cells
AMIGO2 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00320
Species: Human
Expression System: HEK293 Cells
FLRT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02032
Species: Human
Expression System: HEK293 Cells
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